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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of autophagy of mitochondrion
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Accession:GO:1903146 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of mitochondrion degradation by an autophagic process.
Synonyms:broad_synonym: regulation of mitochondrion degradation



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regulation of autophagy of mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP13A2 ATPase cation transporting 13A2 involved_in TAS (PMID:25548531) ParkinsonsUK-UCL PMID:25548531 NCBI chr 1:16,985,958...17,011,928
Ensembl chr 1:16,985,958...17,011,928
JBrowse link
G HAX1 HCLS1 associated protein X-1 involved_in TAS (PMID:24522549) ParkinsonsUK-UCL PMID:24522549 NCBI chr 1:154,272,629...154,275,875
Ensembl chr 1:154,272,355...154,275,875
JBrowse link
G HDAC6 histone deacetylase 6 involved_in TAS (PMID:25548531) ParkinsonsUK-UCL PMID:25548531 NCBI chr  X:48,801,398...48,824,982
Ensembl chr  X:48,801,377...48,824,982
JBrowse link
G HTRA2 HtrA serine peptidase 2 involved_in TAS (PMID:24522549) ParkinsonsUK-UCL PMID:24522549 NCBI chr 2:74,529,405...74,533,556
Ensembl chr 2:74,529,596...74,533,350
JBrowse link
G PINK1 PTEN induced kinase 1 involved_in TAS (PMID:21563316) ParkinsonsUK-UCL PMID:21563316 NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511
JBrowse link
G VDAC1 voltage dependent anion channel 1 involved_in NAS (PMID:20098416) ParkinsonsUK-UCL PMID:20098416 NCBI chr 5:133,971,871...134,114,540
Ensembl chr 5:133,971,871...134,004,975
JBrowse link
negative regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC16A C-type lectin domain containing 16A acts_upstream_of_or_within ISO (PMID:24949970) MGI PMID:24949970 NCBI chr16:10,944,564...11,182,186
Ensembl chr16:10,944,539...11,182,186
JBrowse link
G FBXL4 F-box and leucine rich repeat protein 4 involved_in IDA (PMID:38992176) UniProt PMID:38992176 NCBI chr 6:98,868,535...98,947,946
Ensembl chr 6:98,868,535...98,948,006
JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IMP (PMID:19279012) ParkinsonsUK-UCL PMID:19279012 NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511
JBrowse link
G PPTC7 protein phosphatase targeting COQ7 involved_in IDA (PMID:38992176) UniProt PMID:38992176 NCBI chr12:110,533,245...110,583,318
Ensembl chr12:110,533,245...110,583,318
JBrowse link
G RBX1 ring-box 1 involved_in IC (PMID:17636018) UniProt PMID:17636018 NCBI chr22:40,951,378...40,973,309
Ensembl chr22:40,951,347...40,973,309
JBrowse link
G RNF41 ring finger protein 41 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24949970) Ensembl
MGI
PMID:24949970 GO_REF:0000107 NCBI chr12:56,202,179...56,221,969
Ensembl chr12:56,202,179...56,221,933
JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22044588) Ensembl
MGI
PMID:22044588 GO_REF:0000107 NCBI chr12:4,321,213...4,360,028
Ensembl chr12:4,307,763...4,360,028
JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22044588) Ensembl
MGI
PMID:22044588 GO_REF:0000107 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
JBrowse link
G TSC2 TSC complex subunit 2 involved_in NAS (PMID:26735435) ParkinsonsUK-UCL PMID:26735435 NCBI chr16:2,047,985...2,089,491
Ensembl chr16:2,047,967...2,089,491
JBrowse link
G TSPO translocator protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:43,151,559...43,163,242
Ensembl chr22:43,151,547...43,163,242
JBrowse link
G USP30 ubiquitin specific peptidase 30 involved_in ISO
IEA
RGD
Ensembl
PMID:24896179 GO_REF:0000107 RGD:13208875 NCBI chr12:109,023,089...109,088,023
Ensembl chr12:109,023,089...109,088,023
JBrowse link
negative regulation of type 2 mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HTRA2 HtrA serine peptidase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:74,529,405...74,533,556
Ensembl chr 2:74,529,596...74,533,350
JBrowse link
G VPS13C vacuolar protein sorting 13 homolog C involved_in IMP (PMID:26942284) ParkinsonsUK-UCL PMID:26942284 NCBI chr15:61,852,389...62,060,447
Ensembl chr15:61,852,389...62,060,473
JBrowse link
positive regulation of autophagy of mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BNIP3 BCL2 interacting protein 3 involved_in ISO
IEA
RGD
Ensembl
PMID:23698117 GO_REF:0000107 RGD:11561968 NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,967,684...131,981,967
JBrowse link
G CAMKK2 calcium/calmodulin dependent protein kinase kinase 2 involved_in IC (PMID:26103054) ParkinsonsUK-UCL PMID:26103054 NCBI chr12:121,237,692...121,297,819
Ensembl chr12:121,237,675...121,298,308
JBrowse link
G FBXO7 F-box protein 7 involved_in IBA GO_Central GO_REF:0000033 NCBI chr22:32,474,811...32,498,829
Ensembl chr22:32,474,676...32,498,829
JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in NAS (PMID:24531622) ParkinsonsUK-UCL PMID:24531622 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505
JBrowse link
positive regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMBRA1 autophagy and beclin 1 regulator 1 involved_in IDA (PMID:30217973) UniProt PMID:30217973 NCBI chr11:46,396,412...46,594,023
Ensembl chr11:46,396,414...46,594,125
JBrowse link
G ATG7 autophagy related 7 ISO RGD PMID:37042059 RGD:407532700 NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665
JBrowse link
G CERS1 ceramide synthase 1 involved_in IDA (PMID:22922758) UniProt PMID:22922758 NCBI chr19:18,868,545...18,896,982
Ensembl chr19:18,868,545...18,896,727
JBrowse link
G DELE1 DAP3 binding cell death enhancer 1 involved_in IDA (PMID:38340717) UniProt PMID:38340717 NCBI chr 5:141,923,871...141,942,047
Ensembl chr 5:141,923,855...141,942,047
JBrowse link
G EIF2AK1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in IDA (PMID:38340717) UniProt PMID:38340717 NCBI chr 7:6,022,247...6,059,175
Ensembl chr 7:6,022,247...6,059,175
JBrowse link
G FBXO7 F-box protein 7 involved_in IEA
IDA
(PMID:26310625) Ensembl
ParkinsonsUK-UCL
PMID:26310625 GO_REF:0000107 NCBI chr22:32,474,811...32,498,829
Ensembl chr22:32,474,676...32,498,829
JBrowse link
G HTT huntingtin involved_in IMP (PMID:25686248) ParkinsonsUK-UCL PMID:25686248 NCBI chr 4:3,074,681...3,243,960
Ensembl chr 4:3,041,363...3,243,957
JBrowse link
G IRGM immunity related GTPase M involved_in IDA (PMID:21102437), (PMID:32939830) UniProt PMID:21102437 PMID:32939830 NCBI chr 5:150,846,521...150,902,402
Ensembl chr 5:150,846,521...150,900,736
JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in ISO
IDA
(PMID:26310625) RGD
ParkinsonsUK-UCL
PMID:26310625 PMID:28608965 RGD:13432560 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775
JBrowse link
G SLC25A4 solute carrier family 25 member 4 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 4:185,143,266...185,150,382
Ensembl chr 4:185,143,266...185,150,382
JBrowse link
G SLC25A5 solute carrier family 25 member 5 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr  X:119,468,444...119,471,396
Ensembl chr  X:119,468,422...119,471,396
JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr16:680,410...682,801
Ensembl chr16:680,224...682,870
JBrowse link
G UBE2A ubiquitin conjugating enzyme E2 A involved_in IDA (PMID:23685073) UniProt PMID:23685073 NCBI chr  X:119,574,563...119,584,423
Ensembl chr  X:119,474,802...119,591,083
JBrowse link
G VPS13D vacuolar protein sorting 13 homolog D involved_in IMP (PMID:29307555) UniProt PMID:29307555 NCBI chr 1:12,230,030...12,512,047
Ensembl chr 1:12,230,030...12,512,047
JBrowse link
positive regulation of type 2 mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP5IF1 ATP synthase inhibitory factor subunit 1 involved_in IMP (PMID:24005319) ParkinsonsUK-UCL PMID:24005319 NCBI chr 1:28,236,124...28,238,100
Ensembl chr 1:28,236,109...28,246,906
JBrowse link
G CDC37 cell division cycle 37, HSP90 cochaperone involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:10,391,133...10,403,542
Ensembl chr19:10,391,090...10,420,121
JBrowse link
G GBA1 glucosylceramidase beta 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:23707074) ARUK-UCL
Ensembl
PMID:23707074 GO_REF:0000107 NCBI chr 1:155,234,452...155,244,627
Ensembl chr 1:155,234,452...155,244,699
JBrowse link
G HDAC6 histone deacetylase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:48,801,398...48,824,982
Ensembl chr  X:48,801,377...48,824,982
JBrowse link
G HK2 hexokinase 2 involved_in IMP (PMID:23962723) ParkinsonsUK-UCL PMID:23962723 NCBI chr 2:74,834,127...74,893,359
Ensembl chr 2:74,834,127...74,893,359
JBrowse link
G HUWE1 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 involved_in IDA (PMID:30217973) CACAO PMID:30217973 NCBI chr  X:53,532,096...53,686,719
Ensembl chr  X:53,532,096...53,686,752
JBrowse link
G MUL1 mitochondrial E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:20,499,448...20,508,151
Ensembl chr 1:20,499,448...20,508,151
JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IMP (PMID:20871098) ParkinsonsUK-UCL PMID:20871098 NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IDA
IMP
(PMID:20457763)
(PMID:20871098), (PMID:23212910)
ParkinsonsUK-UCL PMID:20457763 PMID:20871098 PMID:23212910 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775
JBrowse link
G TOMM7 translocase of outer mitochondrial membrane 7 involved_in IMP (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 7:22,812,974...22,822,849
Ensembl chr 7:22,812,628...22,822,849
JBrowse link
G VDAC1 voltage dependent anion channel 1 involved_in IMP (PMID:32047033) UniProt PMID:32047033 NCBI chr 5:133,971,871...134,114,540
Ensembl chr 5:133,971,871...134,004,975
JBrowse link
regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY10 adenylate cyclase 10 involved_in ISO
IEA
RGD
Ensembl
PMID:31172217 GO_REF:0000107 RGD:329403053 NCBI chr 1:167,809,386...167,914,134
Ensembl chr 1:167,809,386...167,914,215
JBrowse link
G BNIP3L BCL2 interacting protein 3 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:26,383,054...26,413,127
Ensembl chr 8:26,383,054...26,505,636
JBrowse link
G CSNK2A2 casein kinase 2 alpha 2 involved_in HMP (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr16:58,157,907...58,198,106
Ensembl chr16:58,157,907...58,198,106
JBrowse link
G CTTN cortactin involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:70,398,529...70,436,575
Ensembl chr11:70,398,404...70,436,584
JBrowse link
G DNM1L dynamin 1 like involved_in IGI (PMID:19279012) ParkinsonsUK-UCL PMID:19279012 NCBI chr12:32,679,301...32,745,650
Ensembl chr12:32,679,200...32,745,650
JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 involved_in IMP (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 4:152,320,544...152,536,092
Ensembl chr 4:152,320,544...152,536,092
JBrowse link
G FKBP8 FKBP prolyl isomerase 8 involved_in IDA (PMID:28381481), (PMID:31908024) DisProt PMID:28381481 PMID:31908024 NCBI chr19:18,531,763...18,543,573
Ensembl chr19:18,531,751...18,544,077
JBrowse link
G FZD5 frizzled class receptor 5 involved_in HMP (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 2:207,762,598...207,769,906
Ensembl chr 2:207,762,598...207,769,906
JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in IMP (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr19:42,230,190...42,242,602
Ensembl chr19:42,226,225...42,242,625
JBrowse link
G PARL presenilin associated rhomboid like involved_in ISS
IEA
(PMID:21355049) ParkinsonsUK-UCL
Ensembl
PMID:21355049 GO_REF:0000107 NCBI chr 3:183,826,489...183,884,880
Ensembl chr 3:183,829,271...183,884,933
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in IMP (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002
JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 involved_in HMP (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr22:41,833,105...41,907,305
Ensembl chr22:41,833,105...41,907,306
JBrowse link
G USP36 ubiquitin specific peptidase 36 involved_in HMP (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr17:78,787,381...78,841,439
Ensembl chr17:78,787,381...78,841,441
JBrowse link
G VDAC1 voltage dependent anion channel 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:133,971,871...134,114,540
Ensembl chr 5:133,971,871...134,004,975
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20486
    cellular process 19728
      process utilizing autophagic mechanism 638
        autophagy 638
          regulation of autophagy 384
            regulation of autophagy of mitochondrion 55
              negative regulation of autophagy of mitochondrion + 13
              positive regulation of autophagy of mitochondrion + 28
              regulation of mitophagy + 50
Path 2
Term Annotations click to browse term
  biological_process 20486
    biological regulation 13634
      regulation of biological process 13232
        regulation of cellular process 12846
          regulation of metabolic process 7662
            regulation of catabolic process 1255
              regulation of autophagy 384
                regulation of autophagy of mitochondrion 55
                  negative regulation of autophagy of mitochondrion + 13
                  positive regulation of autophagy of mitochondrion + 28
                  regulation of mitophagy + 50
paths to the root