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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of autophagy of mitochondrion
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Accession:GO:1903146 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of mitochondrion degradation by an autophagic process.
Synonyms:broad_synonym: regulation of mitochondrion degradation


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negative regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC16A C-type lectin domain containing 16A acts_upstream_of_or_within ISO (PMID:24949970) MGI PMID:24949970 NCBI chr 6:31,560,940...31,757,100
Ensembl chr 6:31,562,834...31,757,678 		JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:78,276,091...78,293,761
Ensembl chr 2:78,277,077...78,294,123 		JBrowse link
G RNF41 ring finger protein 41 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24949970) Ensembl
MGI		 PMID:24949970 GO_REF:0000107 NCBI chr10:512,650...521,293
Ensembl chr10:514,635...542,395 		JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22044588) Ensembl
MGI		 PMID:22044588 GO_REF:0000107 NCBI chr27:40,521,751...40,549,304
Ensembl chr27:40,523,314...40,549,332 		JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22044588) Ensembl
MGI		 PMID:22044588 GO_REF:0000107 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109 		JBrowse link
G TSPO translocator protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:22,388,498...22,399,329
Ensembl chr10:22,274,405...22,399,297 		JBrowse link
G USP30 ubiquitin specific peptidase 30 ISO RGD PMID:24896179 RGD:13208875 NCBI chr26:17,918,852...17,981,947
Ensembl chr26:17,919,512...17,981,846 		JBrowse link
negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VPS13C vacuolar protein sorting 13 homolog C involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:26,600,181...26,776,347
Ensembl chr30:26,601,513...26,776,763 		JBrowse link
positive regulation of autophagy of mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BNIP3 BCL2 interacting protein 3 ISO RGD PMID:23698117 RGD:11561968 NCBI chr28:40,037,681...40,050,499
Ensembl chr28:40,038,643...40,049,797 		JBrowse link
G FBXO7 F-box protein 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:30,928,059...30,948,858
Ensembl chr10:30,928,329...30,948,977 		JBrowse link
positive regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMBRA1 autophagy and beclin 1 regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:42,903,815...43,073,918
Ensembl chr18:42,932,513...43,072,827 		JBrowse link
G CERS1 ceramide synthase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:44,216,568...44,231,820 JBrowse link
G DELE1 DAP3 binding cell death enhancer 1 involved_in ISO (PMID:38340717) UniProt PMID:38340717 NCBI chr 2:36,865,275...36,880,304
Ensembl chr 2:36,865,289...36,879,840 		JBrowse link
G EIF2AK1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in ISO (PMID:38340717) UniProt PMID:38340717 NCBI chr 6:11,447,225...11,478,611
Ensembl chr 6:11,447,081...11,478,658 		JBrowse link
G FBXO7 F-box protein 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:30,928,059...30,948,858
Ensembl chr10:30,928,329...30,948,977 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692 		JBrowse link
G HTT huntingtin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:61,076,934...61,221,462
Ensembl chr 3:61,079,904...61,330,290 		JBrowse link
G LOC481473 immunity-related GTPase family M protein involved_in ISO (PMID:21102437), (PMID:32939830) UniProt PMID:21102437 PMID:32939830 NCBI chr11:793,416...795,373
Ensembl chr11:793,424...794,617 		JBrowse link
G LOC606863 immunity-related GTPase family M protein-like involved_in ISO (MGI:6705154|PMID:33510463) UniProt PMID:33510463 MGI:6705154 NCBI chr11:506,981...523,338
Ensembl chr11:509,636...510,829 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:64,636,850...64,667,232
Ensembl chr 2:64,635,519...64,667,232 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA		 RGD
Ensembl		 PMID:28608965 GO_REF:0000107 RGD:13432560 NCBI chr 1:49,886,887...51,201,930
Ensembl chr 1:49,889,005...51,201,764 		JBrowse link
G SLC25A4 solute carrier family 25 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:45,454,660...45,458,606
Ensembl chr16:45,411,810...45,542,162 		JBrowse link
G SLC25A5 solute carrier family 25 member 5 involved_in ISO (MGI:6407583|PMID:31618756) UniProt PMID:31618756 MGI:6407583 NCBI chr  X:91,523,649...91,526,447
Ensembl chr  X:91,523,643...91,526,479 		JBrowse link
G UBE2A ubiquitin conjugating enzyme E2 A involved_in ISO (PMID:23685073) UniProt PMID:23685073 NCBI chr  X:91,608,936...91,617,993
Ensembl chr  X:91,529,855...91,617,086 		JBrowse link
G VPS13D vacuolar protein sorting 13 homolog D involved_in ISO (PMID:29307555) UniProt PMID:29307555 NCBI chr 2:83,898,620...84,132,453
Ensembl chr 2:83,901,018...84,132,529 		JBrowse link
positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VDAC1 voltage dependent anion channel 1 involved_in ISO (PMID:32047033) UniProt PMID:32047033 NCBI chr11:22,197,814...22,212,924
Ensembl chr11:22,197,949...22,212,924 		JBrowse link
regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY10 adenylate cyclase 10 ISO RGD PMID:31172217 RGD:329403053 NCBI chr 7:30,576,445...30,660,926
Ensembl chr 7:30,577,591...30,660,926 		JBrowse link
G BNIP3L BCL2 interacting protein 3 like involved_in ISO (MGI:5616312|PMID:20200478) ParkinsonsUK-UCL PMID:20200478 MGI:5616312 NCBI chr25:31,133,512...31,149,750
Ensembl chr25:31,136,168...31,148,905 		JBrowse link
G CSNK2A2 casein kinase 2 alpha 2 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 2:58,361,328...58,441,701
Ensembl chr 2:58,360,838...58,432,371 		JBrowse link
G CTTN cortactin involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:47,932,367...47,960,732
Ensembl chr18:47,916,632...47,960,674 		JBrowse link
G DNM1L dynamin 1 like involved_in ISO (PMID:19279012) ParkinsonsUK-UCL PMID:19279012 NCBI chr27:16,161,855...16,211,983
Ensembl chr27:16,163,357...16,211,957 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:50,187,579...50,417,188
Ensembl chr15:50,189,240...50,417,195 		JBrowse link
G FKBP8 FKBP prolyl isomerase 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:44,494,856...44,504,084
Ensembl chr20:44,489,219...44,598,497 		JBrowse link
G FZD5 frizzled class receptor 5 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr37:16,123,788...16,126,634
Ensembl chr37:16,123,798...16,125,567 		JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:112,129,116...112,138,714
Ensembl chr 1:112,103,825...112,138,559 		JBrowse link
G PARL presenilin associated rhomboid like involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:16,790,049...16,837,557
Ensembl chr34:16,781,139...16,837,545 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:41,663,809...41,686,764
Ensembl chr 5:41,663,773...41,686,776 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr10:23,451,923...23,532,765
Ensembl chr10:23,452,561...23,518,689
Ensembl chr10:23,452,561...23,518,689 		JBrowse link
G USP36 ubiquitin specific peptidase 36 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 9:2,547,316...2,587,360
Ensembl chr 9:2,550,452...2,585,108 		JBrowse link
G VDAC1 voltage dependent anion channel 1 involved_in ISO (MGI:5689082|PMID:25470454) ParkinsonsUK-UCL PMID:25470454 MGI:5689082 NCBI chr11:22,197,814...22,212,924
Ensembl chr11:22,197,949...22,212,924 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    cellular process 16926
      process utilizing autophagic mechanism 517
        autophagy 517
          autophagy of mitochondrion 78
            regulation of autophagy of mitochondrion 38
              negative regulation of autophagy of mitochondrion + 7
              positive regulation of autophagy of mitochondrion + 17
              regulation of mitophagy + 37
Path 2
Term Annotations click to browse term
  biological_process 17917
    cellular process 16926
      cellular component organization or biogenesis 6943
        cellular component organization 6705
          organelle organization 3760
            mitochondrion organization 543
              regulation of mitochondrion organization 153
                regulation of autophagy of mitochondrion 38
                  negative regulation of autophagy of mitochondrion + 7
                  positive regulation of autophagy of mitochondrion + 17
                  regulation of mitophagy + 37
paths to the root