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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of autophagy of mitochondrion
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Accession:GO:1903146 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of mitochondrion degradation by an autophagic process.
Synonyms:broad_synonym: regulation of mitochondrion degradation



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negative regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC16A C-type lectin domain containing 16A acts_upstream_of_or_within ISO (PMID:24949970) MGI PMID:24949970 NCBI chr16:9,887,877...10,124,500
Ensembl chr16:11,109,869...11,343,512
JBrowse link
G FBXL4 F-box and leucine rich repeat protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:96,717,103...96,790,932
Ensembl chr 6:100,599,390...100,661,249
JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:19,583,330...19,601,248
Ensembl chr 1:20,627,693...20,645,560
JBrowse link
G PPTC7 protein phosphatase targeting COQ7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:108,103,217...108,152,088
Ensembl chr12:111,499,419...111,548,285
JBrowse link
G RNF41 ring finger protein 41 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24949970) Ensembl
MGI
PMID:24949970 GO_REF:0000107 NCBI chr12:32,693,349...32,710,866
Ensembl chr12:32,944,814...32,962,584
JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22044588) Ensembl
MGI
PMID:22044588 GO_REF:0000107 NCBI chr12:4,429,945...4,462,142
Ensembl chr12:4,353,272...4,385,380
JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22044588) Ensembl
MGI
PMID:22044588 GO_REF:0000107 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
G TSPO translocator protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:24,034,918...24,046,370
Ensembl chr22:42,233,619...42,244,930
JBrowse link
G USP30 ubiquitin specific peptidase 30 ISO RGD PMID:24896179 RGD:13208875 NCBI chr12:106,629,106...106,664,512
Ensembl chr12:110,022,959...110,058,335
JBrowse link
negative regulation of type 2 mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HTRA2 HtrA serine peptidase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:74,596,020...74,599,790
Ensembl chr2A:76,102,240...76,106,152
JBrowse link
G VPS13C vacuolar protein sorting 13 homolog C involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:40,819,512...41,020,644
Ensembl chr15:59,119,001...59,319,619
JBrowse link
positive regulation of autophagy of mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BNIP3 BCL2 interacting protein 3 ISO RGD PMID:23698117 RGD:11561968 NCBI chr10:128,671,663...128,685,952
Ensembl chr10:132,858,211...132,871,634
JBrowse link
G FBXO7 F-box protein 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr22:13,481,255...13,505,301
Ensembl chr22:31,335,423...31,359,224
JBrowse link
positive regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMBRA1 autophagy and beclin 1 regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:46,355,026...46,556,091
Ensembl chr11:46,905,454...47,103,205
JBrowse link
G ATG7 autophagy related 7 ISO RGD PMID:37042059 RGD:407532700 NCBI chr 3:11,208,600...11,488,757
Ensembl chr 3:11,554,100...11,833,398
JBrowse link
G CERS1 ceramide synthase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:18,308,265...18,334,892
Ensembl chr19:19,317,173...19,342,487
JBrowse link
G DELE1 DAP3 binding cell death enhancer 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:137,283,938...137,302,203
Ensembl chr 5:143,394,554...143,412,532
JBrowse link
G EIF2AK1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:7,382,669...7,418,469
Ensembl chr 7:6,222,187...6,256,252
JBrowse link
G FBXO7 F-box protein 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:13,481,255...13,505,301
Ensembl chr22:31,335,423...31,359,224
JBrowse link
G HTT huntingtin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:3,215,081...3,388,587
Ensembl chr 4:3,128,718...3,283,730
JBrowse link
G IRGM immunity related GTPase M involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:146,274,097...146,329,979
Ensembl chr 5:152,278,581...152,308,182
JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:30,955,976...30,995,451
Ensembl chr16:49,837,891...49,873,773
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA
RGD
Ensembl
PMID:28608965 GO_REF:0000107 RGD:13432560 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770
JBrowse link
G SLC25A4 solute carrier family 25 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:177,310,982...177,315,016
Ensembl chr 4:189,531,914...189,534,549
JBrowse link
G SLC25A5 solute carrier family 25 member 5 involved_in ISO (PMID:31618756) UniProt PMID:31618756 NCBI chr  X:108,501,654...108,504,591
Ensembl chr  X:118,926,743...118,929,624
JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 involved_in ISO PMID:29934347 UniProt PMID:29934347 RGD:405650300 Ensembl chr16:694,414...696,682 JBrowse link
G UBE2A ubiquitin conjugating enzyme E2 A involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:108,606,271...108,617,000
Ensembl chr  X:119,034,235...119,049,655
JBrowse link
G VPS13D vacuolar protein sorting 13 homolog D involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:10,978,555...11,260,839
Ensembl chr 1:12,197,389...12,476,612
JBrowse link
positive regulation of type 2 mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP5IF1 ATP synthase inhibitory factor subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:27,495,250...27,497,255
Ensembl chr 1:28,532,091...28,542,607
JBrowse link
G CDC37 cell division cycle 37, HSP90 cochaperone involved_in ISO (PMID:21855797) ParkinsonsUK-UCL PMID:21855797 NCBI chr19:9,942,644...9,955,112
Ensembl chr19:10,606,246...10,618,702
JBrowse link
G GBA1 glucosylceramidase beta 1 acts_upstream_of_or_within ISO (PMID:23707074) ARUK-UCL PMID:23707074 NCBI chr 1:130,579,300...130,589,560
Ensembl chr 1:134,185,385...134,194,851
JBrowse link
G HDAC6 histone deacetylase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:41,099,539...41,122,650
Ensembl chr  X:48,960,430...48,982,642
JBrowse link
G HK2 hexokinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:74,897,914...74,957,234
Ensembl chr2A:76,400,240...76,460,874
JBrowse link
G HUWE1 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:45,746,228...45,897,250
Ensembl chr  X:53,855,404...54,005,366
JBrowse link
G MUL1 mitochondrial E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:19,454,792...19,463,527
Ensembl chr 1:20,496,356...20,505,281
JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:19,583,330...19,601,248
Ensembl chr 1:20,627,693...20,645,560
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770
JBrowse link
G TOMM7 translocase of outer mitochondrial membrane 7 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 7:23,501,438...23,511,321
Ensembl chr 7:23,112,630...23,122,195
JBrowse link
G VDAC1 voltage dependent anion channel 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:129,375,267...129,408,230
Ensembl chr 5:135,529,173...135,560,005
JBrowse link
regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY10 adenylate cyclase 10 ISO RGD PMID:31172217 RGD:329403053 NCBI chr 1:143,239,576...143,404,038
Ensembl chr 1:147,023,671...147,129,705
JBrowse link
G BNIP3L BCL2 interacting protein 3 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:25,661,629...25,685,878
Ensembl chr 8:22,567,428...22,593,004
JBrowse link
G CSNK2A2 casein kinase 2 alpha 2 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr16:38,426,399...38,466,575
Ensembl chr16:57,557,270...57,596,218
JBrowse link
G CTTN cortactin involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:65,500,074...65,539,158
Ensembl chr11:68,794,162...68,823,857
JBrowse link
G DNM1L dynamin 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:53,476,553...53,541,421
Ensembl chr12:56,077,504...56,142,376
JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:144,660,676...144,874,404
Ensembl chr 4:156,312,274...156,402,351
JBrowse link
G FKBP8 FKBP prolyl isomerase 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:18,009,505...18,021,772
Ensembl chr19:18,980,269...18,992,170
JBrowse link
G FZD5 frizzled class receptor 5 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr2B:95,003,246...95,010,577
Ensembl chr2B:213,133,017...213,134,774
JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:39,118,330...39,130,768
Ensembl chr19:47,710,197...47,726,948
JBrowse link
G PARL presenilin associated rhomboid like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:180,862,434...180,921,197
Ensembl chr 3:189,032,816...189,088,036
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:33,458,196...33,484,643
Ensembl chr17:38,405,794...38,432,045
JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr22:22,725,790...22,799,749
Ensembl chr22:40,811,459...40,884,947
JBrowse link
G USP36 ubiquitin specific peptidase 36 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr17:72,871,379...72,916,560
Ensembl chr17:78,416,541...78,461,683
JBrowse link
G VDAC1 voltage dependent anion channel 1 involved_in ISO (PMID:25470454) ParkinsonsUK-UCL PMID:25470454 NCBI chr 5:129,375,267...129,408,230
Ensembl chr 5:135,529,173...135,560,005
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19447
    cellular process 19000
      process utilizing autophagic mechanism 525
        autophagy 525
          regulation of autophagy 312
            regulation of autophagy of mitochondrion 49
              negative regulation of autophagy of mitochondrion + 11
              positive regulation of autophagy of mitochondrion + 26
              regulation of mitophagy + 48
Path 2
Term Annotations click to browse term
  biological_process 19447
    biological regulation 11900
      regulation of biological process 11518
        regulation of cellular process 11168
          regulation of metabolic process 6637
            regulation of catabolic process 1018
              regulation of autophagy 312
                regulation of autophagy of mitochondrion 49
                  negative regulation of autophagy of mitochondrion + 11
                  positive regulation of autophagy of mitochondrion + 26
                  regulation of mitophagy + 48
paths to the root