ONTOLOGY REPORT - ANNOTATIONS
Term: negative regulation of proteolysis involved in protein catabolic process
Accession: GO:1903051
browse the term
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of proteolysis involved in protein catabolic process.
Comment: Overexpression of cathepsin C propeptide significantly increased the degradation of intestinal alkaline phosphatase (IAP).
Synonyms: exact_synonym: down regulation of peptidolysis involved in cellular protein catabolic process; down regulation of peptidolysis involved in cellular protein catabolism; down regulation of proteolysis involved in cellular protein catabolic process; downregulation of peptidolysis involved in cellular protein catabolic process; downregulation of peptidolysis involved in cellular protein catabolism; downregulation of proteolysis involved in cellular protein catabolic process; negative regulation of peptidolysis involved in cellular protein catabolic process; negative regulation of peptidolysis involved in cellular protein catabolism; negative regulation of proteolysis involved in cellular protein catabolic process
narrow_synonym: inhibition of peptidolysis involved in cellular protein catabolic process; inhibition of peptidolysis involved in cellular protein catabolism; inhibition of proteolysis involved in cellular protein catabolic process
related_synonym: down regulation of peptidolysis during cellular protein catabolic process; down regulation of peptidolysis during cellular protein catabolism; down regulation of proteolysis during cellular protein catabolic process; down regulation of proteolysis during cellular protein catabolism; downregulation of peptidolysis during cellular protein catabolic process; downregulation of peptidolysis during cellular protein catabolism; downregulation of proteolysis during cellular protein catabolic process; downregulation of proteolysis during cellular protein catabolism; inhibition of peptidolysis during cellular protein catabolic process; inhibition of peptidolysis during cellular protein catabolism; inhibition of proteolysis during cellular protein catabolic process; inhibition of proteolysis during cellular protein catabolism; negative regulation of peptidolysis during cellular protein catabolic process; negative regulation of peptidolysis during cellular protein catabolism; negative regulation of proteolysis during cellular protein catabolic process; negative regulation of proteolysis during cellular protein catabolism
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Cdkn2a
cyclin-dependent kinase inhibitor 2A
involved_in acts_upstream_of_or_within
ISO
UniProtKB:Q9BXM7 (PMID:25217637) (MGI:5468878|PMID:23277542)
RGD
PMID:23277542 PMID:25217637
MGI:5468878
NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
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Efna1
ephrin A1
involved_in
ISO
UniProtKB:P54764 (PMID:24217950)
RGD
PMID:24217950
NCBI chr 2:174,681,676...174,690,306
Ensembl chr 2:174,681,682...174,690,866
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Epha4
Eph receptor A4
involved_in
ISO
UniProtKB:P20827 (PMID:24217950)
RGD
PMID:24217950
NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139
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Sgta
small glutamine rich tetratricopeptide repeat co-chaperone alpha
involved_in
ISO ISS
(PMID:23129660) GO_REF:0000024
RGD UniProt
PMID:23129660
GO_REF:0000024
NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458
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Svip
small VCP interacting protein
involved_in
IBA ISO IC
PMID:21873635 (PMID:17872946) PMID:17000876
RGD
PMID:17872946 PMID:21873635 PMID:17000876
RGD:13792537 , RGD:10047192
NCBI chr 1:101,587,128...101,592,818
Ensembl chr 1:101,587,128...101,593,116
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Usp14
ubiquitin specific peptidase 14
involved_in
ISO
(PMID:19135427)
RGD
PMID:19135427
NCBI chr18:1,018,111...1,057,727
Ensembl chr18:1,019,400...1,057,519
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Aqp11
aquaporin 11
involved_in
ISS ISO
GO_REF:0000024 (MGI:3813160|PMID:18606867)
UniProt RGD
PMID:18606867
GO_REF:0000024 MGI:3813160
NCBI chr 1:152,046,515...152,056,675
Ensembl chr 1:152,046,517...152,056,725
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Ubxn1
UBX domain protein 1
involved_in
ISO
(PMID:21135095)
RGD
PMID:21135095
NCBI chr 1:205,765,212...205,769,236
Ensembl chr 1:205,745,120...205,816,520
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Usp25
ubiquitin specific peptidase 25
involved_in
ISO
(PMID:22590560)
RGD
PMID:22590560
NCBI chr11:15,603,654...15,711,356
Ensembl chr11:15,603,881...15,711,348
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Alad
aminolevulinate dehydratase
involved_in
ISO
(PMID:8175643)
RGD
PMID:8175643
NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
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F8a1
coagulation factor VIII-associated 1
involved_in
ISO ISS
(PMID:27815841) GO_REF:0000024
RGD UniProt
PMID:27815841
GO_REF:0000024
NCBI chr X:150,957,357...150,958,871
Ensembl chr X:150,916,679...150,960,168
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Gabarapl2
GABA type A receptor associated protein like 2
involved_in
ISO
(PMID:21669198)
RGD
PMID:21669198
NCBI chr19:39,910,572...39,921,408
Ensembl chr19:39,910,534...39,924,628
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Hsp90ab1
heat shock protein 90 alpha family class B member 1
involved_in
IMP ISO
PMID:17517623 (MGI:6148636|PMID:17517623)
RGD
PMID:17517623 PMID:17517623
MGI:6148636 , RGD:13514081
NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
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Lamp3
lysosomal-associated membrane protein 3
involved_in
ISO
(PMID:25681212)
RGD
PMID:25681212
NCBI chr11:81,153,491...81,224,643
Ensembl chr11:81,193,649...81,221,784
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Marchf7
membrane associated ring-CH-type finger 7
involved_in
ISS ISO
GO_REF:0000024 (PMID:29295817)
UniProt RGD
PMID:29295817
GO_REF:0000024
NCBI chr 3:44,680,229...44,720,172
Ensembl chr 3:44,681,632...44,720,168
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Ophn1
oligophrenin 1
involved_in
ISO IBA
(MGI:5303043|PMID:21874017) PMID:21873635
RGD
PMID:21874017 PMID:21873635
MGI:5303043 , RGD:13792537
NCBI chr X:63,599,746...63,976,678
Ensembl chr X:63,603,042...63,976,633
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Prkcg
protein kinase C, gamma
involved_in
ISS ISO
GO_REF:0000024 (MGI:5467682|PMID:23185022)
UniProt RGD
PMID:23185022
GO_REF:0000024 MGI:5467682
NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384
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Psme3ip1
proteasome activator subunit 3 interacting protein 1
involved_in
ISO
(PMID:29934401)
RGD
PMID:29934401
NCBI chr19:10,401,400...10,430,059
Ensembl chr19:10,401,532...10,429,987
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Psmf1
proteasome inhibitor subunit 1
involved_in
IEA ISO ISS
GO_REF:0000107 (PMID:10764772) GO_REF:0000024
Ensembl RGD UniProt
PMID:10764772
GO_REF:0000024 GO_REF:0000107
NCBI chr 3:140,235,371...140,260,546
Ensembl chr 3:140,235,373...140,260,546
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Sco1
synthesis of cytochrome C oxidase 1
acts_upstream_of_or_within
ISO
MGI:2176228|MGI:5758867 (MGI:5643882|PMID:25683716)
RGD
PMID:25683716
MGI:5643882
NCBI chr10:51,744,656...51,757,246
Ensembl chr10:51,744,656...51,757,237
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Usp19
ubiquitin specific peptidase 19
involved_in
ISO
(MGI:5614537|PMID:25088257)
RGD
PMID:25088257
MGI:5614537
NCBI chr 8:109,190,727...109,201,761
Ensembl chr 8:109,190,724...109,201,741
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Bag5
BAG cochaperone 5
involved_in
ISO
(PMID:24475098)
RGD
PMID:24475098
NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970
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Bag6
BAG cochaperone 6
involved_in
ISS IEA ISO
GO_REF:0000024 GO_REF:0000107 (MGI:3808636|PMID:18678708)
UniProt Ensembl RGD
PMID:18678708
GO_REF:0000024 GO_REF:0000107 MGI:3808636
NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657
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Camlg
calcium modulating ligand
involved_in
ISO
UniProtKB:Q9H9V4 (PMID:20553626)
RGD
PMID:20553626
NCBI chr17:8,992,697...9,003,576
Ensembl chr17:8,992,696...9,003,552
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Ccar2
cell cycle and apoptosis regulator 2
involved_in
ISO
(PMID:23398316)
RGD
PMID:23398316
NCBI chr15:45,212,797...45,228,001
Ensembl chr15:45,212,803...45,227,636
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Clec16a
C-type lectin domain containing 16A
acts_upstream_of_or_within
ISO
MGI:5648633 (MGI:5603233|PMID:24949970)
RGD
PMID:24949970
MGI:5603233
NCBI chr10:4,927,804...5,123,749
Ensembl chr10:4,928,030...5,123,578
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Ddrgk1
DDRGK domain containing 1
involved_in
ISO
(PMID:28263186)
RGD
PMID:28263186
NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680
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Eif3h
eukaryotic translation initiation factor 3, subunit H
involved_in
ISO
(PMID:32269044)
RGD
PMID:32269044
NCBI chr 7:83,091,045...83,174,436
Ensembl chr 7:83,091,039...83,174,451
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Fhit
fragile histidine triad diadenosine triphosphatase
involved_in
ISO ISS IBA
(PMID:15313915) GO_REF:0000024 PMID:21873635
RGD UniProt
PMID:15313915 PMID:21873635
GO_REF:0000024, RGD:13792537
NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340
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Gipc1
GIPC PDZ domain containing family, member 1
involved_in
ISO
(MGI:3807767|PMID:11546783)
RGD
PMID:11546783
MGI:3807767
NCBI chr19:24,474,291...24,487,083
Ensembl chr19:24,453,123...24,486,997
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Hsp90ab1
heat shock protein 90 alpha family class B member 1
involved_in acts_upstream_of_or_within
ISS ISO
GO_REF:0000024 (PMID:16280321) (PMID:24613385)
UniProt MGI RGD
PMID:16280321 PMID:24613385
GO_REF:0000024
NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
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Klhl40
kelch-like family member 40
involved_in acts_upstream_of_or_within
IBA ISO
PMID:21873635 (MGI:5586592|PMID:24960163)
RGD
PMID:24960163 PMID:21873635
MGI:5586592 , RGD:13792537
NCBI chr 8:121,441,275...121,446,806
Ensembl chr 8:121,441,287...121,446,800
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Map1a
microtubule-associated protein 1A
involved_in
ISO
(MGI:5703671|PMID:26609151)
RGD
PMID:26609151
MGI:5703671
NCBI chr 3:108,263,217...108,283,936
Ensembl chr 3:108,263,151...108,282,899
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Mtm1
myotubularin 1
acts_upstream_of_or_within
ISO
MGI:2450997 (MGI:5510937|PMID:23695157)
RGD
PMID:23695157
MGI:5510937
NCBI chr 6:488,691...506,964
Ensembl chr 6:488,969...506,860
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N4bp1
Nedd4 binding protein 1
involved_in
IBA ISO
PMID:21873635 (MGI:3829128|PMID:17592138)
RGD
PMID:17592138 PMID:21873635
MGI:3829128 , RGD:13792537
NCBI chr19:20,222,811...20,273,570
Ensembl chr19:20,222,776...20,273,570
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Nop53
NOP53 ribosome biogenesis factor
involved_in
ISO
(PMID:22522597)
RGD
PMID:22522597
NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902
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Ogt
O-linked N-acetylglucosamine (GlcNAc) transferase
involved_in
IEA ISO
GO_REF:0000107 (PMID:26678539)
Ensembl RGD
PMID:26678539
GO_REF:0000107
NCBI chr X:66,771,278...66,816,148
Ensembl chr X:66,771,349...66,816,146
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Park7
Parkinsonism associated deglycase
involved_in
ISO
(PMID:17015834)
RGD
PMID:17015834
NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
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Pbk
PDZ binding kinase
acts_upstream_of_or_within
ISO
MGI:5293435 (MGI:5293269|PMID:21715333)
RGD
PMID:21715333
MGI:5293269
NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014
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Phf20l1
PHD finger protein 20-like 1
involved_in
ISS ISO
GO_REF:0000024 (PMID:24492612)
UniProt RGD
PMID:24492612
GO_REF:0000024
NCBI chr 7:98,330,580...98,396,526
Ensembl chr 7:98,330,580...98,396,526
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Rpl11
ribosomal protein L11
involved_in
ISS ISO
GO_REF:0000024 (MGI:5897550|PMID:21804542)
UniProt RGD
PMID:21804542
GO_REF:0000024 MGI:5897550
NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599
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Rybp
RING1 and YY1 binding protein
involved_in
ISO
(PMID:27060496)
RGD
PMID:27060496
NCBI chr 4:132,876,361...132,927,580 NCBI chr 4:132,876,260...132,929,075
Ensembl chr 4:132,876,361...132,928,316
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Sdcbp
syndecan binding protein
involved_in
ISO ISS
(PMID:25893292) GO_REF:0000024
RGD UniProt
PMID:25893292
GO_REF:0000024
NCBI chr 5:19,473,499...19,517,188
Ensembl chr 5:19,489,961...19,527,572
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Senp1
SUMO specific peptidase 1
acts_upstream_of_or_within
ISO
MGI:3818522 (MGI:3818351|PMID:17981124)
RGD
PMID:17981124
MGI:3818351
NCBI chr 7:129,163,173...129,226,766
Ensembl chr 7:129,165,774...129,221,598
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Shh
sonic hedgehog signaling molecule
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 (MGI:3624046|PMID:16611981)
Ensembl RGD
PMID:16611981
GO_REF:0000107 MGI:3624046
NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
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Smarcc1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
acts_upstream_of_or_within
ISO
(MGI:5310666|PMID:22285184)
RGD
PMID:22285184
MGI:5310666
NCBI chr 8:110,111,097...110,214,727
Ensembl chr 8:110,111,122...110,214,720
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Taf9
TATA-box binding protein associated factor 9
involved_in
ISO IEA
(PMID:11278372) GO_REF:0000107
RGD Ensembl
PMID:11278372
GO_REF:0000107
NCBI chr 2:31,794,316...31,798,324
Ensembl chr 2:31,794,142...31,798,769
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Tlk2
tousled-like kinase 2
involved_in
ISO
(PMID:20016786)
RGD
PMID:20016786
NCBI chr10:90,154,449...90,248,562
Ensembl chr10:90,156,813...90,248,561
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Trim39
tripartite motif-containing 39
involved_in
IBA IEA ISS ISO
PMID:21873635 GO_REF:0000107 GO_REF:0000024 (PMID:23213251)
Ensembl UniProt RGD
PMID:23213251 PMID:21873635
GO_REF:0000024 GO_REF:0000107, RGD:13792537
NCBI chr20:2,003,320...2,017,175
Ensembl chr20:1,983,533...2,020,117
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Ttc36
tetratricopeptide repeat domain 36
acts_upstream_of_or_within
ISO
MGI:5588394 (MGI:6362140|PMID:31537781)
RGD
PMID:31537781
MGI:6362140
NCBI chr 8:45,112,737...45,116,345
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Ubxn1
UBX domain protein 1
involved_in
ISS IBA ISO
GO_REF:0000024 PMID:21873635 (PMID:20351172)
UniProt RGD
PMID:20351172 PMID:21873635
GO_REF:0000024, RGD:13792537
NCBI chr 1:205,765,212...205,769,236
Ensembl chr 1:205,745,120...205,816,520
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Uchl5
ubiquitin C-terminal hydrolase L5
involved_in
ISO
(PMID:23770237)
RGD
PMID:23770237
NCBI chr13:55,520,722...55,556,503
Ensembl chr13:55,520,729...55,556,502
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Usp7
ubiquitin specific peptidase 7
involved_in
ISO
(PMID:26678539)
RGD
PMID:26678539
NCBI chr10:6,880,684...6,925,033
Ensembl chr10:6,828,795...6,925,355
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Usp9x
ubiquitin specific peptidase 9, X-linked
involved_in
ISO
(PMID:33378666)
RGD
PMID:33378666
NCBI chr X:9,588,825...9,726,993
Ensembl chr X:9,588,825...9,696,711
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Wac
WW domain containing adaptor with coiled-coil
involved_in
ISO
(PMID:22354037)
RGD
PMID:22354037
NCBI chr17:55,922,686...55,984,286
Ensembl chr17:55,923,123...55,982,301
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Pabpn1l
PABPN1 like
acts_upstream_of_or_within
ISO
(MGI:6509513|PMID:32558204)
RGD
PMID:32558204
MGI:6509513
NCBI chr19:50,669,965...50,673,409
Ensembl chr19:50,669,967...50,673,366
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Styx
serine/threonine/tyrosine interacting protein
involved_in
IBA ISO
PMID:21873635 (PMID:28007894)
RGD
PMID:28007894 PMID:21873635
RGD:13792537
NCBI chr15:18,565,214...18,595,797
Ensembl chr15:18,564,633...18,593,524
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Anks1a
ankyrin repeat and sterile alpha motif domain containing 1A
acts_upstream_of_or_within
ISO
(MGI:4461099|PMID:20100865)
RGD
PMID:20100865
MGI:4461099
NCBI chr20:5,963,658...6,117,139
Ensembl chr20:5,963,678...6,117,148
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Cdkn2a
cyclin-dependent kinase inhibitor 2A
involved_in acts_upstream_of_or_within
ISO
(PMID:16173922) (PMID:18560357) (MGI:5468878|PMID:23277542)
RGD
PMID:16173922 PMID:18560357 PMID:23277542
MGI:5468878
NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
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Csnk2a1
casein kinase 2 alpha 1
involved_in
ISO
UniProtKB:P19784|UniProtKB:P25686|UniProtKB:P67870 (PMID:28031292)
RGD
PMID:28031292
NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696
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Csnk2a2
casein kinase 2 alpha 2
involved_in
ISO
UniProtKB:P25686|UniProtKB:P67870|UniProtKB:P68400 (PMID:28031292)
RGD
PMID:28031292
NCBI chr19:9,556,443...9,596,080
Ensembl chr19:9,556,260...9,596,080
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Hfe
homeostatic iron regulator
involved_in
ISO
(PMID:24904118)
RGD
PMID:24904118
NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502
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Hipk2
homeodomain interacting protein kinase 2
involved_in
ISO
(PMID:21628596)
RGD
PMID:21628596
NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223
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Pdcl3
phosducin-like 3
acts_upstream_of_or_within
ISO
(PMID:23792958)
RGD
PMID:23792958
NCBI chr 9:41,234,322...41,243,769
Ensembl chr 9:41,234,234...41,243,735
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Pml
PML nuclear body scaffold
involved_in
ISO
(PMID:15195100)
RGD
PMID:15195100
NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
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Prmt6
protein arginine methyltransferase 6
involved_in
ISO
(MGI:5688415|PMID:26070566)
RGD
PMID:26070566
MGI:5688415
NCBI chr 2:197,927,750...197,932,980
Ensembl chr 2:197,927,220...197,933,648
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Psen1
presenilin 1
involved_in
ISO
(MGI:4887523|PMID:20208556)
RGD
PMID:20208556
MGI:4887523
NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650
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Psen2
presenilin 2
involved_in
ISO
(MGI:4887523|PMID:20208556)
RGD
PMID:20208556
MGI:4887523
NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174
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Qrich2
glutamine rich 2
involved_in
ISO
(PMID:30683861) (MGI:6277293|PMID:30683861)
RGD
PMID:30683861
MGI:6277293
NCBI chr10:101,669,235...101,685,281 NCBI chr10:101,685,289...101,686,370 NCBI chr10:101,686,862...101,688,070 NCBI chr10:101,688,451...101,697,637
Ensembl chr10:101,669,224...101,697,656
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Rpl11
ribosomal protein L11
involved_in
ISO
(PMID:18560357)
RGD
PMID:18560357
NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599
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Rpl23
ribosomal protein L23
involved_in
ISO
(PMID:15314173)
RGD
PMID:15314173
NCBI chr10:82,771,878...82,775,840
Ensembl chr10:82,771,538...82,775,870
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Rpl5
ribosomal protein L5
involved_in
ISO
(PMID:18560357)
RGD
PMID:18560357
NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290
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Rps7
ribosomal protein S7
involved_in
ISO
(PMID:17310983)
RGD
PMID:17310983
NCBI chr 6:45,266,200...45,271,064
Ensembl chr 6:45,223,980...45,271,145
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Sgta
small glutamine rich tetratricopeptide repeat co-chaperone alpha
involved_in
ISS ISO
GO_REF:0000024 (PMID:23129660)
UniProt RGD
PMID:23129660
GO_REF:0000024
NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458
G
Sufu
SUFU negative regulator of hedgehog signaling
acts_upstream_of_or_within
ISO
MGI:1343085 (MGI:4355593|PMID:19684112)
RGD
PMID:19684112
MGI:4355593
NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577
G
Taf1
TATA-box binding protein associated factor 1
involved_in
ISO
(PMID:17237821)
RGD
PMID:17237821
NCBI chr X:66,640,915...66,716,543
Ensembl chr X:66,640,982...66,716,543
G
Trim39
tripartite motif-containing 39
involved_in
ISO
(PMID:19100260)
RGD
PMID:19100260
NCBI chr20:2,003,320...2,017,175
Ensembl chr20:1,983,533...2,020,117
G
Wnt1
Wnt family member 1
acts_upstream_of_or_within
ISO
(MGI:3628833|PMID:16601693)
RGD
PMID:16601693
MGI:3628833
NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all