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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of proteolysis involved in protein catabolic process
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Accession:GO:1903050 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of proteolysis involved in cellular catabolic process.
Comment:overexpression of cathepsin C propeptide significantly increased the degradation of intestinal alkaline phosphatase (IAP)
Synonyms:exact_synonym: regulation of peptidolysis involved in cellular protein catabolic process;   regulation of peptidolysis involved in cellular protein catabolism;   regulation of proteolysis involved in cellular protein catabolic process
 related_synonym: regulation of peptidolysis during cellular protein catabolic process;   regulation of peptidolysis during cellular protein catabolism;   regulation of proteolysis during cellular protein catabolic process;   regulation of proteolysis during cellular protein catabolism


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negative regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IDA (PMID:23129660) UniProt PMID:23129660 NCBI chr19:2,754,715...2,783,273
Ensembl chr19:2,754,715...2,783,362 		JBrowse link
G SVIP small VCP interacting protein involved_in IMP
IBA		 (PMID:17872946)
(PMID:21873635)		 UniProt
GO_Central		 PMID:17872946 PMID:21873635 NCBI chr11:22,818,927...22,829,801
Ensembl chr11:22,813,799...22,830,299 		JBrowse link
G USP14 ubiquitin specific peptidase 14 involved_in IMP (PMID:19135427) ParkinsonsUK-UCL PMID:19135427 NCBI chr18:158,557...214,629
Ensembl chr18:158,383...214,629 		JBrowse link
negative regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP11 aquaporin 11 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:77,589,953...77,610,356
Ensembl chr11:77,589,391...77,610,356 		JBrowse link
G UBXN1 UBX domain protein 1 involved_in IMP (PMID:21135095) ParkinsonsUK-UCL PMID:21135095 NCBI chr11:62,676,500...62,679,073
Ensembl chr11:62,676,498...62,679,117 		JBrowse link
G USP25 ubiquitin specific peptidase 25 involved_in IMP (PMID:22590560) ParkinsonsUK-UCL PMID:22590560 NCBI chr21:15,729,982...15,880,064
Ensembl chr21:15,729,982...15,880,064 		JBrowse link
negative regulation of proteasomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALAD aminolevulinate dehydratase involved_in IDA (PMID:8175643) CAFA PMID:8175643 NCBI chr 9:113,386,312...113,401,284
Ensembl chr 9:113,386,312...113,401,290 		JBrowse link
G F8A1 coagulation factor VIII associated 1 involved_in IMP (PMID:27815841) UniProt PMID:27815841 NCBI chr  X:154,886,355...154,888,061
Ensembl chr  X:154,886,355...154,888,061 		JBrowse link
G F8A2 coagulation factor VIII associated 2 involved_in IMP (PMID:27815841) UniProt PMID:27815841 NCBI chr  X:155,382,095...155,383,801
Ensembl chr  X:155,382,095...155,383,801 		JBrowse link
G F8A3 coagulation factor VIII associated 3 involved_in IMP (PMID:27815841) UniProt PMID:27815841 NCBI chr  X:155,456,914...155,458,620
Ensembl chr  X:155,456,914...155,458,620 		JBrowse link
G GABARAPL2 GABA type A receptor associated protein like 2 involved_in IMP (PMID:21669198) BHF-UCL PMID:21669198 NCBI chr16:75,566,379...75,577,881
Ensembl chr16:75,566,375...75,577,881 		JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 involved_in ISS
IEA		 (PMID:17517623) ARUK-UCL
Ensembl		 PMID:17517623 GO_REF:0000107 NCBI chr 6:44,246,194...44,253,883
Ensembl chr 6:44,246,166...44,253,888 		JBrowse link
G LAMP3 lysosomal associated membrane protein 3 involved_in IMP (PMID:25681212) ParkinsonsUK-UCL PMID:25681212 NCBI chr 3:183,122,215...183,163,813
Ensembl chr 3:183,122,215...183,163,839 		JBrowse link
G MARCHF7 membrane associated ring-CH-type finger 7 involved_in IMP (PMID:29295817) UniProt PMID:29295817 NCBI chr 2:159,712,506...159,771,027
Ensembl chr 2:159,712,457...159,771,027 		JBrowse link
G OPHN1 oligophrenin 1 involved_in IEA
IBA		 (PMID:21873635) Ensembl
GO_Central		 PMID:21873635 GO_REF:0000107 NCBI chr  X:68,042,344...68,433,841
Ensembl chr  X:67,949,349...68,433,913 		JBrowse link
G PRKCG protein kinase C gamma involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr19:53,881,094...53,907,652
Ensembl chr19:53,879,190...53,907,652 		JBrowse link
G PSME3IP1 proteasome activator subunit 3 interacting protein 1 involved_in IMP (PMID:29934401) UniProt PMID:29934401 NCBI chr16:57,152,466...57,186,116
Ensembl chr16:57,152,466...57,186,116 		JBrowse link
G PSMF1 proteasome inhibitor subunit 1 involved_in IDA (PMID:10764772) UniProt PMID:10764772 NCBI chr20:1,113,263...1,172,246
Ensembl chr20:1,113,240...1,189,415 		JBrowse link
G SCO1 synthesis of cytochrome C oxidase 1 acts_upstream_of_or_within ISO (MGI:5643882|PMID:25683716) MGI PMID:25683716 MGI:5643882 NCBI chr17:10,672,474...10,697,533
Ensembl chr17:10,672,474...10,698,375 		JBrowse link
G USP19 ubiquitin specific peptidase 19 involved_in ISO (MGI:5614537|PMID:25088257) ParkinsonsUK-UCL PMID:25088257 MGI:5614537 NCBI chr 3:49,108,050...49,120,823
Ensembl chr 3:49,108,046...49,120,938 		JBrowse link
negative regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG5 BAG cochaperone 5 involved_in IDA (PMID:24475098) ParkinsonsUK-UCL PMID:24475098 NCBI chr14:103,556,551...103,562,657
Ensembl chr14:103,556,545...103,562,657 		JBrowse link
G BAG6 BAG cochaperone 6 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:31,639,028...31,652,661
Ensembl chr 6:31,639,028...31,652,705 		JBrowse link
G CAMLG calcium modulating ligand involved_in IMP (PMID:20553626) UniProt PMID:20553626 NCBI chr 5:134,738,548...134,752,157
Ensembl chr 5:134,738,495...134,752,157 		JBrowse link
G CCAR2 cell cycle and apoptosis regulator 2 involved_in IDA (PMID:23398316) UniProt PMID:23398316 NCBI chr 8:22,604,757...22,621,514
Ensembl chr 8:22,604,757...22,620,964 		JBrowse link
G CLEC16A C-type lectin domain containing 16A acts_upstream_of_or_within ISO (MGI:5603233|PMID:24949970) MGI PMID:24949970 MGI:5603233 NCBI chr16:10,944,564...11,182,186
Ensembl chr16:10,944,539...11,182,186 		JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IMP (PMID:28263186) UniProt PMID:28263186 NCBI chr20:3,190,350...3,204,682
Ensembl chr20:3,190,350...3,204,685 		JBrowse link
G EIF3H eukaryotic translation initiation factor 3 subunit H involved_in IDA (PMID:32269044) FlyBase PMID:32269044 NCBI chr 8:116,642,130...116,766,374
Ensembl chr 8:116,642,130...116,766,925 		JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase involved_in IMP
IBA		 (PMID:15313915)
(PMID:21873635)		 UniProt
GO_Central		 PMID:15313915 PMID:21873635 NCBI chr 3:59,747,277...61,251,452
Ensembl chr 3:59,747,277...61,251,459 		JBrowse link
G GIPC1 GIPC PDZ domain containing family member 1 involved_in IEA
ISS		 Ensembl
BHF-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr19:14,477,762...14,496,127
Ensembl chr19:14,477,760...14,496,149 		JBrowse link
G HFE homeostatic iron regulator involved_in IC (PMID:24904118) BHF-UCL PMID:24904118 NCBI chr 6:26,087,429...26,098,343
Ensembl chr 6:26,087,281...26,098,343 		JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 involved_in IDA (PMID:24613385) UniProt PMID:24613385 NCBI chr 6:44,246,194...44,253,883
Ensembl chr 6:44,246,166...44,253,888 		JBrowse link
G KLHL40 kelch like family member 40 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:5586592|PMID:24960163)
(PMID:21873635)		 MGI
GO_Central		 PMID:21873635 PMID:24960163 MGI:5586592 NCBI chr 3:42,685,537...42,692,544
Ensembl chr 3:42,685,537...42,692,544 		JBrowse link
G MAP1A microtubule associated protein 1A involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr15:43,510,954...43,531,611
Ensembl chr15:43,510,958...43,531,620 		JBrowse link
G MTM1 myotubularin 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5510937|PMID:23695157) MGI
Ensembl		 PMID:23695157 GO_REF:0000107 MGI:5510937 NCBI chr  X:150,562,653...150,673,143
Ensembl chr  X:150,568,417...150,673,143 		JBrowse link
G N4BP1 NEDD4 binding protein 1 involved_in IEA
ISS
IBA		 (PMID:21873635) Ensembl
UniProt
GO_Central		 PMID:21873635 GO_REF:0000024 GO_REF:0000107 NCBI chr16:48,538,726...48,610,180
Ensembl chr16:48,538,726...48,620,148 		JBrowse link
G NOP53 NOP53 ribosome biogenesis factor involved_in IMP (PMID:22522597) UniProt PMID:22522597 NCBI chr19:47,745,546...47,757,058
Ensembl chr19:47,745,546...47,757,058 		JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IMP (PMID:26678539) UniProt PMID:26678539 NCBI chr  X:71,533,104...71,575,892
Ensembl chr  X:71,533,087...71,575,892 		JBrowse link
G PANO1 proapoptotic nucleolar protein 1 involved_in IMP (PMID:22094112) UniProt PMID:22094112 NCBI chr11:797,626...799,192
Ensembl chr11:797,511...799,190 		JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in IDA (PMID:17015834) ParkinsonsUK-UCL PMID:17015834 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505 		JBrowse link
G PBK PDZ binding kinase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5293269|PMID:21715333) MGI
Ensembl		 PMID:21715333 GO_REF:0000107 MGI:5293269 NCBI chr 8:27,809,624...27,837,817
Ensembl chr 8:27,809,624...27,838,082 		JBrowse link
G PHF20L1 PHD finger protein 20 like 1 involved_in IMP (PMID:24492612) UniProt PMID:24492612 NCBI chr 8:132,775,388...132,848,807
Ensembl chr 8:132,775,358...132,848,807 		JBrowse link
G RPL11 ribosomal protein L11 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:23,691,779...23,696,835
Ensembl chr 1:23,691,742...23,696,835 		JBrowse link
G RYBP RING1 and YY1 binding protein involved_in IMP (PMID:27060496) UniProt PMID:27060496 NCBI chr 3:72,374,593...72,446,623
Ensembl chr 3:72,371,825...72,446,621 		JBrowse link
G SDCBP syndecan binding protein involved_in IMP (PMID:25893292) UniProt PMID:25893292 NCBI chr 8:58,553,261...58,582,858
Ensembl chr 8:58,552,924...58,582,859 		JBrowse link
G SENP1 SUMO specific peptidase 1 acts_upstream_of_or_within ISO (MGI:3818351|PMID:17981124) MGI PMID:17981124 MGI:3818351 NCBI chr12:48,042,897...48,106,079
Ensembl chr12:48,042,897...48,106,079 		JBrowse link
G SHH sonic hedgehog signaling molecule acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3624046|PMID:16611981) MGI
Ensembl		 PMID:16611981 GO_REF:0000107 MGI:3624046 NCBI chr 7:155,799,980...155,812,463
Ensembl chr 7:155,799,980...155,812,463 		JBrowse link
G SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5310666|PMID:22285184) MGI
Ensembl		 PMID:22285184 GO_REF:0000107 MGI:5310666 NCBI chr 3:47,585,269...47,781,893
Ensembl chr 3:47,585,269...47,782,106 		JBrowse link
G TAF9 TATA-box binding protein associated factor 9 involved_in IDA (PMID:11278372) BHF-UCL PMID:11278372 NCBI chr 5:69,364,743...69,369,824
Ensembl chr 5:69,362,026...69,370,013 		JBrowse link
G TLK2 tousled like kinase 2 involved_in IMP (PMID:20016786) UniProt PMID:20016786 NCBI chr17:62,470,914...62,615,481
Ensembl chr17:62,458,658...62,615,481 		JBrowse link
G TRIM39 tripartite motif containing 39 involved_in IBA
IMP		 (PMID:21873635)
(PMID:23213251)		 GO_Central
UniProt		 PMID:21873635 PMID:23213251 NCBI chr 6:30,326,469...30,343,729
Ensembl chr 6:30,326,479...30,343,729 		JBrowse link
G TTC36 tetratricopeptide repeat domain 36 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:6362140|PMID:31537781) MGI
Ensembl		 PMID:31537781 GO_REF:0000107 MGI:6362140 NCBI chr11:118,527,474...118,530,993
Ensembl chr11:118,527,472...118,531,197 		JBrowse link
G UBXN1 UBX domain protein 1 involved_in IDA
IBA		 (PMID:20351172)
(PMID:21873635)		 UniProt
GO_Central		 PMID:20351172 PMID:21873635 NCBI chr11:62,676,500...62,679,073
Ensembl chr11:62,676,498...62,679,117 		JBrowse link
G UCHL5 ubiquitin C-terminal hydrolase L5 involved_in IMP (PMID:23770237) UniProt PMID:23770237 NCBI chr 1:193,012,254...193,060,076
Ensembl chr 1:193,012,250...193,060,080 		JBrowse link
G USP7 ubiquitin specific peptidase 7 involved_in IMP (PMID:26678539) UniProt PMID:26678539 NCBI chr16:8,892,097...8,963,906
Ensembl chr16:8,892,097...8,975,328 		JBrowse link
G USP9X ubiquitin specific peptidase 9 X-linked involved_in IMP (PMID:33378666) UniProt PMID:33378666 NCBI chr  X:41,085,445...41,236,579
Ensembl chr  X:41,085,445...41,236,579 		JBrowse link
G WAC WW domain containing adaptor with coiled-coil involved_in IMP (PMID:22354037) BHF-UCL PMID:22354037 NCBI chr10:28,532,779...28,623,112
Ensembl chr10:28,532,493...28,623,112 		JBrowse link
negative regulation of proteolysis involved in protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN2A cyclin dependent kinase inhibitor 2A acts_upstream_of_or_within
involved_in		 ISO
IMP		 (MGI:5468878|PMID:23277542)
(PMID:25217637)		 MGI
ParkinsonsUK-UCL		 PMID:23277542 PMID:25217637 MGI:5468878 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301 		JBrowse link
G EFNA1 ephrin A1 involved_in IGI (PMID:24217950) ARUK-UCL PMID:24217950 NCBI chr 1:155,127,876...155,134,899
Ensembl chr 1:155,127,876...155,134,899 		JBrowse link
G EPHA4 EPH receptor A4 involved_in IGI (PMID:24217950) ARUK-UCL PMID:24217950 NCBI chr 2:221,418,027...221,574,202
Ensembl chr 2:221,418,027...221,574,202 		JBrowse link
negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PABPN1L PABPN1 like, cytoplasmic acts_upstream_of_or_within ISO (MGI:6509513|PMID:32558204) MGI PMID:32558204 MGI:6509513 NCBI chr16:88,863,333...88,870,135
Ensembl chr16:88,863,333...88,866,660 		JBrowse link
G STYX serine/threonine/tyrosine interacting protein involved_in IBA
IMP		 (PMID:21873635)
(PMID:28007894)		 GO_Central
UniProt		 PMID:21873635 PMID:28007894 NCBI chr14:52,730,166...52,774,989
Ensembl chr14:52,730,166...52,774,989 		JBrowse link
negative regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A acts_upstream_of_or_within ISO (MGI:4461099|PMID:20100865) MGI PMID:20100865 MGI:4461099 NCBI chr 6:34,889,255...35,097,990
Ensembl chr 6:34,889,255...35,091,406 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A acts_upstream_of_or_within
involved_in		 ISO
IDA		 (MGI:5468878|PMID:23277542)
(PMID:16173922), (PMID:18560357)		 MGI
UniProt		 PMID:16173922 PMID:18560357 PMID:23277542 MGI:5468878 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301 		JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 involved_in IGI (PMID:28031292) ARUK-UCL PMID:28031292 NCBI chr20:472,498...543,790
Ensembl chr20:472,498...543,835 		JBrowse link
G CSNK2A2 casein kinase 2 alpha 2 involved_in IGI (PMID:28031292) ARUK-UCL PMID:28031292 NCBI chr16:58,157,907...58,198,106
Ensembl chr16:58,157,907...58,198,106 		JBrowse link
G HFE homeostatic iron regulator involved_in IDA (PMID:24904118) BHF-UCL PMID:24904118 NCBI chr 6:26,087,429...26,098,343
Ensembl chr 6:26,087,281...26,098,343 		JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 involved_in IMP (PMID:21628596) FlyBase PMID:21628596 NCBI chr 7:139,561,570...139,777,998
Ensembl chr 7:139,561,570...139,777,998 		JBrowse link
G PDCL3 phosducin like 3 acts_upstream_of_or_within IMP (PMID:23792958) MGI PMID:23792958 NCBI chr 2:100,562,993...100,576,739
Ensembl chr 2:100,562,993...100,576,739 		JBrowse link
G PML PML nuclear body scaffold involved_in IMP (PMID:15195100) UniProt PMID:15195100 NCBI chr15:73,994,716...74,047,827
Ensembl chr15:73,994,673...74,047,827 		JBrowse link
G PRMT6 protein arginine methyltransferase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:107,056,674...107,059,294
Ensembl chr 1:107,056,674...107,067,636 		JBrowse link
G PSEN1 presenilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:73,136,417...73,223,691
Ensembl chr14:73,136,418...73,223,691 		JBrowse link
G PSEN2 presenilin 2 involved_in ISO (MGI:4887523|PMID:20208556) BHF-UCL PMID:20208556 MGI:4887523 NCBI chr 1:226,870,616...226,903,668
Ensembl chr 1:226,870,184...226,927,726 		JBrowse link
G QRICH2 glutamine rich 2 involved_in IMP (PMID:30683861) UniProt PMID:30683861 NCBI chr17:76,274,049...76,310,964
Ensembl chr17:76,274,049...76,308,276 		JBrowse link
G RPL11 ribosomal protein L11 involved_in IMP (PMID:18560357) CAFA PMID:18560357 NCBI chr 1:23,691,779...23,696,835
Ensembl chr 1:23,691,742...23,696,835 		JBrowse link
G RPL23 ribosomal protein L23 involved_in IDA (PMID:15314173) CAFA PMID:15314173 NCBI chr17:38,847,860...38,853,721
Ensembl chr17:38,847,860...38,853,764 		JBrowse link
G RPL5 ribosomal protein L5 involved_in IDA (PMID:18560357) CAFA PMID:18560357 NCBI chr 1:92,831,986...92,841,924
Ensembl chr 1:92,832,013...92,841,924 		JBrowse link
G RPS7 ribosomal protein S7 involved_in IDA (PMID:17310983) CAFA PMID:17310983 NCBI chr 2:3,575,260...3,580,920
Ensembl chr 2:3,575,260...3,580,920 		JBrowse link
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IDA (PMID:23129660) UniProt PMID:23129660 NCBI chr19:2,754,715...2,783,273
Ensembl chr19:2,754,715...2,783,362 		JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4355593|PMID:19684112) MGI
Ensembl		 PMID:19684112 GO_REF:0000107 MGI:4355593 NCBI chr10:102,502,819...102,633,535
Ensembl chr10:102,503,972...102,633,535 		JBrowse link
G TAF1 TATA-box binding protein associated factor 1 involved_in IMP (PMID:17237821) ParkinsonsUK-UCL PMID:17237821 NCBI chr  X:71,366,357...71,530,525
Ensembl chr  X:71,366,222...71,532,374 		JBrowse link
G TRIM39 tripartite motif containing 39 involved_in IDA (PMID:19100260) BHF-UCL PMID:19100260 NCBI chr 6:30,326,469...30,343,729
Ensembl chr 6:30,326,479...30,343,729 		JBrowse link
G WNT1 Wnt family member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3628833|PMID:16601693) MGI
Ensembl		 PMID:16601693 GO_REF:0000107 MGI:3628833 NCBI chr12:48,978,322...48,982,620
Ensembl chr12:48,978,322...48,982,620 		JBrowse link
positive regulation of anaphase-promoting complex-dependent catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC20 cell division cycle 20 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:43,358,981...43,363,203
Ensembl chr 1:43,358,981...43,363,203 		JBrowse link
G CDC20B cell division cycle 20B involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:55,112,971...55,173,177
Ensembl chr 5:55,112,971...55,173,177 		JBrowse link
G FZR1 fizzy and cell division cycle 20 related 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr19:3,506,311...3,538,334
Ensembl chr19:3,506,311...3,538,334 		JBrowse link
positive regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCAP31 B cell receptor associated protein 31 involved_in IGI (PMID:18555783) ParkinsonsUK-UCL PMID:18555783 NCBI chr  X:153,700,492...153,724,387
Ensembl chr  X:153,700,492...153,724,565 		JBrowse link
G CAV1 caveolin 1 involved_in IMP (PMID:24089527) ParkinsonsUK-UCL PMID:24089527 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179 		JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in IDA
IMP		 (PMID:22045699)
(PMID:18307982)		 ParkinsonsUK-UCL
UniProt		 PMID:18307982 PMID:22045699 NCBI chr16:56,932,142...56,944,864
Ensembl chr16:56,932,142...56,944,864 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 involved_in TAS (PMID:23800989) ParkinsonsUK-UCL PMID:23800989 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IMP (PMID:23246001) ParkinsonsUK-UCL PMID:23246001 NCBI chr19:2,754,715...2,783,273
Ensembl chr19:2,754,715...2,783,362 		JBrowse link
G UBQLN1 ubiquilin 1 involved_in IMP (PMID:18307982) UniProt PMID:18307982 NCBI chr 9:83,659,968...83,707,958
Ensembl chr 9:83,659,968...83,707,958 		JBrowse link
G UBQLN2 ubiquilin 2 involved_in IMP (PMID:18307982) UniProt PMID:18307982 NCBI chr  X:56,563,627...56,567,868
Ensembl chr  X:56,563,627...56,567,868 		JBrowse link
G XBP1 X-box binding protein 1 involved_in TAS (PMID:22013210) ParkinsonsUK-UCL PMID:22013210 NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597 		JBrowse link
positive regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATXN3 ataxin 3 involved_in IMP (PMID:17000876) ParkinsonsUK-UCL PMID:17000876 NCBI chr14:92,058,552...92,106,582
Ensembl chr14:92,044,496...92,106,621 		JBrowse link
G BAG6 BAG cochaperone 6 involved_in IMP (PMID:24424410) ParkinsonsUK-UCL PMID:24424410 NCBI chr 6:31,639,028...31,652,661
Ensembl chr 6:31,639,028...31,652,705 		JBrowse link
G RNF185 ring finger protein 185 involved_in IMP (PMID:27485036) UniProt PMID:27485036 NCBI chr22:31,160,182...31,207,019
Ensembl chr22:31,160,182...31,207,019 		JBrowse link
G RNFT1 ring finger protein, transmembrane 1 involved_in IBA
IEA
IMP		 (PMID:21873635)
(PMID:27485036)		 GO_Central
InterPro
UniProt		 PMID:21873635 PMID:27485036 GO_REF:0000002 NCBI chr17:59,952,240...59,964,740
Ensembl chr17:59,952,240...59,964,761 		JBrowse link
G RNFT2 ring finger protein, transmembrane 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr12:116,738,315...116,853,631
Ensembl chr12:116,738,178...116,853,631 		JBrowse link
G TMEM259 transmembrane protein 259 involved_in IBA
IEA		 (PMID:21873635) GO_Central
Ensembl		 PMID:21873635 GO_REF:0000107 NCBI chr19:1,009,653...1,021,123
Ensembl chr19:1,009,648...1,021,179 		JBrowse link
G TMEM67 transmembrane protein 67 ISO RGD PMID:19815549 RGD:8554391 NCBI chr 8:93,754,844...93,832,653
Ensembl chr 8:93,754,844...93,819,234 		JBrowse link
G USP13 ubiquitin specific peptidase 13 involved_in IMP (PMID:24424410) ParkinsonsUK-UCL PMID:24424410 NCBI chr 3:179,653,040...179,789,401
Ensembl chr 3:179,653,032...179,804,366 		JBrowse link
G WFS1 wolframin ER transmembrane glycoprotein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:6,269,850...6,303,265
Ensembl chr 4:6,269,849...6,303,265 		JBrowse link
positive regulation of proteasomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG2 BAG cochaperone 2 involved_in ISS
IEA		 (PMID:19228967) ARUK-UCL
Ensembl		 PMID:19228967 GO_REF:0000107 NCBI chr 6:57,172,326...57,189,833
Ensembl chr 6:57,172,326...57,189,833 		JBrowse link
G DAB2IP DAB2 interacting protein involved_in IMP (PMID:20080667) UniProt PMID:20080667 NCBI chr 9:121,567,074...121,785,530
Ensembl chr 9:121,567,057...121,785,530 		JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IMP (PMID:23675531) UniProt PMID:23675531 NCBI chr20:3,190,350...3,204,682
Ensembl chr20:3,190,350...3,204,685 		JBrowse link
G ECSCR endothelial cell surface expressed chemotaxis and apoptosis regulator acts_upstream_of_or_within
involved_in		 IMP
IBA		 (PMID:19416853)
(PMID:21873635)		 MGI
GO_Central		 PMID:19416853 PMID:21873635 NCBI chr 5:139,448,560...139,462,743
Ensembl chr 5:139,448,560...139,462,743 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 involved_in IEA
IDA		 (PMID:23858059) Ensembl
ParkinsonsUK-UCL		 PMID:23858059 GO_REF:0000107 NCBI chr 4:152,320,544...152,536,092
Ensembl chr 4:152,320,544...152,536,092 		JBrowse link
G FMR1 fragile X messenger ribonucleoprotein 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr  X:147,911,919...147,951,125
Ensembl chr  X:147,911,919...147,951,125 		JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in IDA (PMID:22180649) BHF-UCL PMID:22180649 NCBI chr21:34,364,006...34,371,381
Ensembl chr21:34,364,006...34,371,381 		JBrowse link
G NUPR1 nuclear protein 1, transcriptional regulator involved_in IMP (PMID:16300740) UniProt PMID:16300740 NCBI chr16:28,532,708...28,538,974
Ensembl chr16:28,532,708...28,539,008 		JBrowse link
G OSBPL7 oxysterol binding protein like 7 involved_in IMP (PMID:21669198) BHF-UCL PMID:21669198 NCBI chr17:47,807,372...47,821,794
Ensembl chr17:47,807,372...47,821,834 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IGI (PMID:23858059) ParkinsonsUK-UCL PMID:23858059 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G PSMC1 proteasome 26S subunit, ATPase 1 involved_in IEA GOC GO_REF:0000108 NCBI chr14:90,256,553...90,275,429
Ensembl chr14:90,256,527...90,275,429 		JBrowse link
G PSMC2 proteasome 26S subunit, ATPase 2 involved_in IEA
IC		 (PMID:9464850) GOC
UniProt		 PMID:9464850 GO_REF:0000108 NCBI chr 7:103,347,524...103,369,395
Ensembl chr 7:103,328,570...103,370,346 		JBrowse link
G PSMC3 proteasome 26S subunit, ATPase 3 involved_in IC
IEA		 (PMID:9464850) UniProt
GOC		 PMID:9464850 GO_REF:0000108 NCBI chr11:47,418,775...47,426,439
Ensembl chr11:47,418,769...47,426,473 		JBrowse link
G PSMC4 proteasome 26S subunit, ATPase 4 involved_in IEA GOC GO_REF:0000108 NCBI chr19:39,971,165...39,981,764
Ensembl chr19:39,971,165...39,981,764 		JBrowse link
G PSMC5 proteasome 26S subunit, ATPase 5 involved_in IC
IEA		 (PMID:9464850) UniProt
GOC		 PMID:9464850 GO_REF:0000108 NCBI chr17:63,827,431...63,832,019
Ensembl chr17:63,827,152...63,832,026 		JBrowse link
G PSMC6 proteasome 26S subunit, ATPase 6 involved_in IEA
IC		 (PMID:9464850) GOC
UniProt		 PMID:9464850 GO_REF:0000108 NCBI chr14:52,707,200...52,728,590
Ensembl chr14:52,707,178...52,728,590 		JBrowse link
G RNF40 ring finger protein 40 ISO RGD PMID:12121982 RGD:633892 NCBI chr16:30,761,612...30,776,307
Ensembl chr16:30,761,745...30,776,307 		JBrowse link
G TMTC3 transmembrane O-mannosyltransferase targeting cadherins 3 involved_in IMP (PMID:21603654) UniProt PMID:21603654 NCBI chr12:88,142,307...88,199,887
Ensembl chr12:88,142,296...88,199,887 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISS
IEA		 (PMID:29518356) ARUK-UCL
Ensembl		 PMID:29518356 GO_REF:0000107 NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186 		JBrowse link
G XBP1 X-box binding protein 1 acts_upstream_of_or_within ISO (MGI:4946566|PMID:21317886) MGI PMID:21317886 MGI:4946566 NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597 		JBrowse link
positive regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 acts_upstream_of_or_within
involved_in		 ISO
IDA
IEA		 (MGI:3589701|PMID:15937334)
(PMID:23512198)		 MGI
UniProt
Ensembl		 PMID:15937334 PMID:23512198 GO_REF:0000107 MGI:3589701 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G ANKIB1 ankyrin repeat and IBR domain containing 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:92,245,974...92,401,383
Ensembl chr 7:92,245,974...92,401,383 		JBrowse link
G ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:72,474,330...72,602,987
Ensembl chr15:72,474,330...72,602,987 		JBrowse link
G ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:48,918,842...48,986,382
Ensembl chr 3:48,918,821...48,986,382 		JBrowse link
G ATG7 autophagy related 7 acts_upstream_of_or_within ISO (MGI:5465208|PMID:23152632) MGI PMID:23152632 MGI:5465208 NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665 		JBrowse link
G AURKA aurora kinase A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3697244|PMID:17060449) MGI
Ensembl		 PMID:17060449 GO_REF:0000107 MGI:3697244 NCBI chr20:56,369,390...56,392,215
Ensembl chr20:56,369,389...56,392,337 		JBrowse link
G AXIN1 axin 1 acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 (MGI:3628833|PMID:16601693)
(PMID:21873635)		 MGI
GO_Central
Ensembl		 PMID:16601693 PMID:21873635 GO_REF:0000107 MGI:3628833 NCBI chr16:287,440...352,723
Ensembl chr16:287,440...352,723 		JBrowse link
G AXIN2 axin 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:65,528,563...65,561,648
Ensembl chr17:65,528,563...65,561,648 		JBrowse link
G BAG2 BAG cochaperone 2 NOT|involved_in ISS (PMID:19228967) ARUK-UCL PMID:19228967 NCBI chr 6:57,172,326...57,189,833
Ensembl chr 6:57,172,326...57,189,833 		JBrowse link
G BBS7 Bardet-Biedl syndrome 7 acts_upstream_of_or_within IPI (PMID:22302990) MGI PMID:22302990 NCBI chr 4:121,824,329...121,870,474
Ensembl chr 4:121,824,329...121,870,487 		JBrowse link
G CBFA2T3 CBFA2/RUNX1 partner transcriptional co-repressor 3 involved_in IMP (PMID:25974097) UniProt PMID:25974097 NCBI chr16:88,874,858...88,977,207
Ensembl chr16:88,874,858...88,977,207 		JBrowse link
G CEBPA CCAAT enhancer binding protein alpha involved_in TAS (PMID:14685163) ParkinsonsUK-UCL PMID:14685163 NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534 		JBrowse link
G CHFR checkpoint with forkhead and ring finger domains acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5310666|PMID:22285184) MGI
Ensembl		 PMID:22285184 GO_REF:0000107 MGI:5310666 NCBI chr12:132,832,356...132,887,618
Ensembl chr12:132,822,187...132,956,304 		JBrowse link
G CLU clusterin involved_in IMP
IBA		 (PMID:20068069)
(PMID:21873635)		 UniProt
GO_Central		 PMID:20068069 PMID:21873635 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700 		JBrowse link
G COP1 COP1 E3 ubiquitin ligase involved_in IMP (PMID:19805145) UniProt PMID:19805145 NCBI chr 1:175,944,831...176,207,286
Ensembl chr 1:175,944,831...176,207,286 		JBrowse link
G CSNK1A1 casein kinase 1 alpha 1 involved_in IDA
IMP		 (PMID:19364825)
(PMID:11955436)		 FlyBase
ParkinsonsUK-UCL		 PMID:11955436 PMID:19364825 NCBI chr 5:149,492,982...149,551,439
Ensembl chr 5:149,492,982...149,551,471 		JBrowse link
G CSNK1D casein kinase 1 delta involved_in ISS
IBA		 (PMID:21873635) UniProt
GO_Central		 PMID:21873635 GO_REF:0000024 NCBI chr17:82,239,019...82,273,750
Ensembl chr17:82,239,023...82,273,700 		JBrowse link
G CSNK1E casein kinase 1 epsilon involved_in ISS
IBA
IEA		 (PMID:21873635) UniProt
GO_Central
Ensembl		 PMID:21873635 GO_REF:0000024 GO_REF:0000107 NCBI chr22:38,290,691...38,318,084
Ensembl chr22:38,290,691...38,318,084 		JBrowse link
G DAB2 DAB adaptor protein 2 involved_in IMP (PMID:12805222) BHF-UCL PMID:12805222 NCBI chr 5:39,371,677...39,424,980
Ensembl chr 5:39,371,675...39,462,300 		JBrowse link
G DDA1 DET1 and DDB1 associated 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr19:17,309,563...17,323,298
Ensembl chr19:17,309,518...17,323,298 		JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IMP (PMID:23675531) ParkinsonsUK-UCL PMID:23675531 NCBI chr20:3,190,350...3,204,682
Ensembl chr20:3,190,350...3,204,685 		JBrowse link
G DET1 DET1 partner of COP1 E3 ubiquitin ligase involved_in IPI
IBA		 (PMID:14739464)
(PMID:21873635)		 UniProt
GO_Central		 PMID:14739464 PMID:21873635 NCBI chr15:88,501,919...88,546,703
Ensembl chr15:88,494,440...88,546,681 		JBrowse link
G DNAJB2 DnaJ heat shock protein family (Hsp40) member B2 involved_in IDA
IBA
TAS		 (PMID:15936278)
(PMID:21873635)
(PMID:28031292)		 BHF-UCL
GO_Central
ARUK-UCL		 PMID:15936278 PMID:21873635 PMID:28031292 NCBI chr 2:219,279,366...219,286,895
Ensembl chr 2:219,279,342...219,286,898 		JBrowse link
G DVL1 dishevelled segment polarity protein 1 involved_in IMP (PMID:20177058) BHF-UCL PMID:20177058 NCBI chr 1:1,335,278...1,349,418
Ensembl chr 1:1,335,276...1,349,418 		JBrowse link
G ELOB elongin B involved_in ISS FlyBase GO_REF:0000024 NCBI chr16:2,771,414...2,777,280
Ensembl chr16:2,771,414...2,777,289 		JBrowse link
G FBXO22 F-box protein 22 acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 (MGI:3840749|PMID:19319192)
(PMID:21873635)		 MGI
GO_Central
Ensembl		 PMID:19319192 PMID:21873635 GO_REF:0000107 MGI:3840749 NCBI chr15:75,903,878...75,942,511
Ensembl chr15:75,903,876...75,942,511 		JBrowse link
G GABARAP GABA type A receptor-associated protein involved_in IMP (PMID:25684205) UniProt PMID:25684205 NCBI chr17:7,240,008...7,242,449
Ensembl chr17:7,240,008...7,242,449 		JBrowse link
G GBA1 glucosylceramidase beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:155,234,452...155,244,627
Ensembl chr 1:155,234,452...155,244,699 		JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3695876|PMID:17189825) MGI
Ensembl		 PMID:17189825 GO_REF:0000107 MGI:3695876 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970 		JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in IMP (PMID:25897075) ARUK-UCL PMID:25897075 NCBI chr19:42,230,190...42,242,602
Ensembl chr19:42,226,225...42,242,625 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta acts_upstream_of_or_within
involved_in		 ISO
IDA
IC
IMP		 (MGI:5437589|PMID:22660580)
(PMID:19364825), (PMID:22660580)
(PMID:11955436)
(PMID:25897075)		 MGI
UniProt
ParkinsonsUK-UCL
ARUK-UCL		 PMID:11955436 PMID:19364825 PMID:22660580 PMID:25897075 MGI:5437589 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G HECTD1 HECT domain E3 ubiquitin protein ligase 1 involved_in ISS FlyBase GO_REF:0000024 NCBI chr14:31,100,117...31,207,793
Ensembl chr14:31,100,117...31,207,804 		JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A involved_in IDA
IBA		 (PMID:24613385)
(PMID:21873635)		 UniProt
GO_Central		 PMID:21873635 PMID:24613385 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946 		JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B involved_in IDA
IBA		 (PMID:24613385)
(PMID:21873635)		 UniProt
GO_Central		 PMID:21873635 PMID:24613385 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254 		JBrowse link
G HSPBP1 HSPA (Hsp70) binding protein 1 involved_in IDA (PMID:16831871) BHF-UCL PMID:16831871 NCBI chr19:55,262,223...55,280,383
Ensembl chr19:55,262,223...55,280,381 		JBrowse link
G IL33 interleukin 33 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5437589|PMID:22660580) MGI
Ensembl		 PMID:22660580 GO_REF:0000107 MGI:5437589 NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 involved_in TAS (PMID:17015834) ParkinsonsUK-UCL PMID:17015834 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558 		JBrowse link
G KLHL40 kelch like family member 40 involved_in ISS UniProt GO_REF:0000024 NCBI chr 3:42,685,537...42,692,544
Ensembl chr 3:42,685,537...42,692,544 		JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in IEA
ISS		 Ensembl
BHF-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:40,224,997...40,369,285
Ensembl chr12:40,196,744...40,369,285 		JBrowse link
G MDM2 MDM2 proto-oncogene involved_in IDA (PMID:11278372) BHF-UCL PMID:11278372 NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544 		JBrowse link
G NKD2 NKD inhibitor of WNT signaling pathway 2 involved_in IMP (PMID:20177058) BHF-UCL PMID:20177058 NCBI chr 5:1,008,802...1,038,943
Ensembl chr 5:1,008,802...1,038,943 		JBrowse link
G NOP53 NOP53 ribosome biogenesis factor involved_in IMP
IEA		 (PMID:25818168), (PMID:27323397) UniProt
Ensembl		 PMID:25818168 PMID:27323397 GO_REF:0000107 NCBI chr19:47,745,546...47,757,058
Ensembl chr19:47,745,546...47,757,058 		JBrowse link
G NUB1 negative regulator of ubiquitin like proteins 1 involved_in IMP (PMID:16707496) UniProt PMID:16707496 NCBI chr 7:151,341,812...151,378,449
Ensembl chr 7:151,341,772...151,378,449 		JBrowse link
G PABIR1 PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 involved_in IMP (PMID:27588481) UniProt PMID:27588481 NCBI chr 9:68,780,065...68,785,566
Ensembl chr 9:68,780,065...68,785,566 		JBrowse link
G PIAS1 protein inhibitor of activated STAT 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr15:68,054,315...68,193,847
Ensembl chr15:68,054,309...68,198,603 		JBrowse link
G PLK1 polo like kinase 1 involved_in IMP (PMID:19473992) UniProt PMID:19473992 NCBI chr16:23,678,889...23,690,367
Ensembl chr16:23,677,656...23,690,367 		JBrowse link
G PLK2 polo like kinase 2 ISO RGD PMID:18723513 RGD:7241135 NCBI chr 5:58,453,982...58,460,086
Ensembl chr 5:58,453,982...58,460,139 		JBrowse link
G PRICKLE1 prickle planar cell polarity protein 1 involved_in IDA (PMID:17030191) BHF-UCL PMID:17030191 NCBI chr12:42,456,757...42,589,746
Ensembl chr12:42,456,757...42,590,355 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in TAS
IEA
IBA		 (PMID:24115276)
(PMID:21873635)		 ParkinsonsUK-UCL
Ensembl
GO_Central		 PMID:21873635 PMID:24115276 GO_REF:0000107 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G PSEN1 presenilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:73,136,417...73,223,691
Ensembl chr14:73,136,418...73,223,691 		JBrowse link
G PSEN2 presenilin 2 involved_in ISO (MGI:4887523|PMID:20208556) BHF-UCL PMID:20208556 MGI:4887523 NCBI chr 1:226,870,616...226,903,668
Ensembl chr 1:226,870,184...226,927,726 		JBrowse link
G PSMD10 proteasome 26S subunit, non-ATPase 10 involved_in TAS
IDA		 (PMID:10613832)
(PMID:16023600)		 UniProt PMID:10613832 PMID:16023600 NCBI chr  X:108,084,207...108,091,542
Ensembl chr  X:108,084,207...108,091,549 		JBrowse link
G RACK1 receptor for activated C kinase 1 involved_in IDA (PMID:19785988) UniProt PMID:19785988 NCBI chr 5:181,236,897...181,243,906
Ensembl chr 5:181,236,897...181,248,096 		JBrowse link
G RAD23A RAD23 homolog A, nucleotide excision repair protein involved_in IMP (PMID:26296656) CAFA PMID:26296656 NCBI chr19:12,945,862...12,953,642
Ensembl chr19:12,945,855...12,953,642 		JBrowse link
G RBX1 ring-box 1 involved_in IPI (PMID:14739464) UniProt PMID:14739464 NCBI chr22:40,951,378...40,973,309
Ensembl chr22:40,951,347...40,973,309 		JBrowse link
G RCHY1 ring finger and CHY zinc finger domain containing 1 involved_in IDA (PMID:19483087) UniProt PMID:19483087 NCBI chr 4:75,479,033...75,514,715
Ensembl chr 4:75,479,033...75,514,764 		JBrowse link
G RFPL1 ret finger protein like 1 involved_in IMP (PMID:20725088) UniProt PMID:20725088 NCBI chr22:29,387,909...29,442,455
Ensembl chr22:29,438,583...29,442,455 		JBrowse link
G RNF14 ring finger protein 14 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:141,949,337...141,990,292
Ensembl chr 5:141,958,328...141,990,292 		JBrowse link
G RNF144A ring finger protein 144A involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:6,917,412...7,076,367
Ensembl chr 2:6,917,412...7,068,286 		JBrowse link
G RNF144B ring finger protein 144B involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:18,387,350...18,468,870
Ensembl chr 6:18,387,350...18,468,870 		JBrowse link
G RNF180 ring finger protein 180 acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 (MGI:3819024|PMID:18363970), (MGI:5505713|PMID:23926250)
(PMID:21873635)		 MGI
GO_Central
Ensembl		 PMID:18363970 PMID:21873635 PMID:23926250 GO_REF:0000107 MGI:3819024 MGI:5505713 NCBI chr 5:64,165,351...64,372,869
Ensembl chr 5:64,165,843...64,372,869 		JBrowse link
G RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:100,257,067...100,336,204
Ensembl chr 8:100,257,060...100,336,218 		JBrowse link
G RNF19B ring finger protein 19B involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:32,929,036...32,964,809
Ensembl chr 1:32,936,445...32,964,809 		JBrowse link
G RNF217 ring finger protein 217 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:124,962,437...125,092,634
Ensembl chr 6:124,962,437...125,092,633 		JBrowse link
G SH3RF1 SH3 domain containing ring finger 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:169,094,259...169,270,956
Ensembl chr 4:169,094,259...169,270,956 		JBrowse link
G SH3RF2 SH3 domain containing ring finger 2 involved_in IBA
IMP
IEA		 (PMID:21873635)
(PMID:22128169)		 GO_Central
UniProt
Ensembl		 PMID:21873635 PMID:22128169 GO_REF:0000107 NCBI chr 5:145,936,578...146,081,773
Ensembl chr 5:145,936,578...146,081,791 		JBrowse link
G SH3RF3 SH3 domain containing ring finger 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:109,129,205...109,504,634
Ensembl chr 2:109,129,205...109,504,634 		JBrowse link
G SIRT2 sirtuin 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr19:38,878,555...38,899,618
Ensembl chr19:38,878,555...38,899,862 		JBrowse link
G SMAD7 SMAD family member 7 involved_in IDA (PMID:11278251) BHF-UCL PMID:11278251 NCBI chr18:48,919,853...48,950,965
Ensembl chr18:48,919,853...48,950,965 		JBrowse link
G SOCS4 suppressor of cytokine signaling 4 involved_in IEA InterPro GO_REF:0000002 NCBI chr14:55,027,236...55,049,489
Ensembl chr14:55,027,230...55,049,489 		JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in IMP
IEA		 (PMID:15590694) UniProt
InterPro		 PMID:15590694 GO_REF:0000002 NCBI chr 2:46,698,937...46,763,129
Ensembl chr 2:46,698,952...46,780,245 		JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 involved_in IDA (PMID:11146632) HGNC-UCL PMID:11146632 NCBI chr16:680,410...682,801
Ensembl chr16:680,224...682,870 		JBrowse link
G SUMO1 small ubiquitin like modifier 1 involved_in IDA (PMID:18408734) UniProt PMID:18408734 NCBI chr 2:202,206,171...202,238,597
Ensembl chr 2:202,206,182...202,238,599 		JBrowse link
G SUMO2 small ubiquitin like modifier 2 involved_in IDA (PMID:18408734) UniProt PMID:18408734 NCBI chr17:75,165,586...75,182,959
Ensembl chr17:75,165,586...75,182,959 		JBrowse link
G TAF1 TATA-box binding protein associated factor 1 involved_in IDA (PMID:15053879) BHF-UCL PMID:15053879 NCBI chr  X:71,366,357...71,530,525
Ensembl chr  X:71,366,222...71,532,374 		JBrowse link
G TPTEP2-CSNK1E TPTEP2-CSNK1E readthrough involved_in ISS
IBA
IEA		 (PMID:21873635) UniProt
GO_Central
Ensembl		 PMID:21873635 GO_REF:0000024 GO_REF:0000107 NCBI chr22:38,290,691...38,398,915
Ensembl chr22:38,291,918...38,398,522 		JBrowse link
G TRIB1 tribbles pseudokinase 1 involved_in IEA
IBA
ISS		 (PMID:21873635)
(PMID:20410507)		 Ensembl
GO_Central
BHF-UCL		 PMID:20410507 PMID:21873635 GO_REF:0000107 NCBI chr 8:125,430,358...125,438,403
Ensembl chr 8:125,430,358...125,438,403 		JBrowse link
G TRIB2 tribbles pseudokinase 2 involved_in ISS
IBA
IEA		 (PMID:20410507)
(PMID:21873635)		 BHF-UCL
GO_Central
Ensembl		 PMID:20410507 PMID:21873635 GO_REF:0000107 NCBI chr 2:12,716,936...12,742,734
Ensembl chr 2:12,716,910...12,742,734 		JBrowse link
G TRIB3 tribbles pseudokinase 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr20:380,760...397,559
Ensembl chr20:362,835...397,559 		JBrowse link
G UBE2V2 ubiquitin conjugating enzyme E2 V2 ISO RGD PMID:12750002 RGD:1299567 NCBI chr 8:47,997,437...48,064,708
Ensembl chr 8:48,008,415...48,064,708 		JBrowse link
G USP5 ubiquitin specific peptidase 5 involved_in IMP (PMID:19098288) UniProt PMID:19098288 NCBI chr12:6,852,150...6,866,632
Ensembl chr12:6,852,148...6,866,632 		JBrowse link
G VCP valosin containing protein involved_in IDA (PMID:9452483) BHF-UCL PMID:9452483 NCBI chr 9:35,056,064...35,072,625
Ensembl chr 9:35,053,928...35,072,668 		JBrowse link
G ZER1 zyg-11 related cell cycle regulator involved_in IMP (PMID:31273098) UniProt PMID:31273098 NCBI chr 9:128,729,786...128,772,486
Ensembl chr 9:128,729,786...128,772,414 		JBrowse link
G ZFAND2A zinc finger AN1-type containing 2A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3663213|PMID:16973439) MGI
Ensembl		 PMID:16973439 GO_REF:0000107 MGI:3663213 NCBI chr 7:1,148,850...1,160,196
Ensembl chr 7:1,152,071...1,160,759 		JBrowse link
G ZYG11B zyg-11 family member B, cell cycle regulator involved_in IMP (PMID:31273098) UniProt PMID:31273098 NCBI chr 1:52,726,453...52,827,336
Ensembl chr 1:52,726,453...52,827,336 		JBrowse link
positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLK3 polo like kinase 3 involved_in IDA (PMID:20889502) UniProt PMID:20889502 NCBI chr 1:44,800,377...44,805,990
Ensembl chr 1:44,800,377...44,805,990 		JBrowse link
G SIRT2 sirtuin 2 involved_in IMP (PMID:24681946) UniProt PMID:24681946 NCBI chr19:38,878,555...38,899,618
Ensembl chr19:38,878,555...38,899,862 		JBrowse link
positive regulation of proteolysis involved in protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP5IF1 ATP synthase inhibitory factor subunit 1 involved_in IMP (PMID:24005319) ParkinsonsUK-UCL PMID:24005319 NCBI chr 1:28,236,124...28,238,100
Ensembl chr 1:28,236,109...28,246,906 		JBrowse link
G CTSC cathepsin C involved_in ISS
IEA		 (PMID:18307834) BHF-UCL
Ensembl		 PMID:18307834 GO_REF:0000107 NCBI chr11:88,293,592...88,337,736
Ensembl chr11:88,265,069...88,359,684 		JBrowse link
G GBA1 glucosylceramidase beta 1 involved_in IEA
IMP		 (PMID:21700325) Ensembl
ParkinsonsUK-UCL		 PMID:21700325 GO_REF:0000107 NCBI chr 1:155,234,452...155,244,627
Ensembl chr 1:155,234,452...155,244,699 		JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in ISO (MGI:5444793|PMID:22949502) ARUK-UCL PMID:22949502 MGI:5444793 NCBI chr 1:30,732,469...30,757,774
Ensembl chr 1:30,732,469...30,757,774 		JBrowse link
G RGN regucalcin involved_in ISO
IEA		 RGD
Ensembl		 PMID:1513338 GO_REF:0000107 RGD:9590188 NCBI chr  X:47,078,443...47,093,313
Ensembl chr  X:47,078,355...47,093,314 		JBrowse link
positive regulation of transcription factor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBXW8 F-box and WD repeat domain containing 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:116,910,950...117,031,148
Ensembl chr12:116,910,950...117,031,148 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 involved_in ISO (MGI:6148490|PMID:29153991) UniProt PMID:29153991 MGI:6148490 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099 		JBrowse link
G SIRT6 sirtuin 6 involved_in IMP (PMID:27457971) CACAO PMID:27457971 NCBI chr19:4,174,109...4,182,563
Ensembl chr19:4,174,109...4,182,566 		JBrowse link
positive regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGBL4 AGBL carboxypeptidase 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:6149282|PMID:29593216) MGI
Ensembl		 PMID:29593216 GO_REF:0000107 MGI:6149282 NCBI chr 1:48,522,511...50,023,954
Ensembl chr 1:48,532,854...50,023,954 		JBrowse link
G AGTPBP1 ATP/GTP binding carboxypeptidase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:6149282|PMID:29593216) MGI
Ensembl		 PMID:29593216 GO_REF:0000107 MGI:6149282 NCBI chr 9:85,546,539...85,805,483
Ensembl chr 9:85,546,539...85,742,029 		JBrowse link
G AXIN1 axin 1 acts_upstream_of_or_within
involved_in		 ISO
IEA
ISS		 (MGI:3628833|PMID:16601693) MGI
Ensembl
BHF-UCL		 PMID:16601693 GO_REF:0000024 GO_REF:0000107 MGI:3628833 NCBI chr16:287,440...352,723
Ensembl chr16:287,440...352,723 		JBrowse link
G CAV3 caveolin 3 involved_in NAS (PMID:22879586) BHF-UCL PMID:22879586 NCBI chr 3:8,733,802...8,746,758
Ensembl chr 3:8,733,802...8,841,808 		JBrowse link
G CCDC22 coiled-coil domain containing 22 involved_in IBA
IMP		 (PMID:21873635)
(PMID:23563313)		 GO_Central
UniProt		 PMID:21873635 PMID:23563313 NCBI chr  X:49,235,470...49,250,520
Ensembl chr  X:49,235,470...49,250,520 		JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 NOT|involved_in IDA (PMID:16173922) UniProt PMID:16173922 NCBI chr17:47,967,904...47,981,781
Ensembl chr17:47,967,810...47,981,781 		JBrowse link
G CLU clusterin involved_in IMP (PMID:20068069) UniProt PMID:20068069 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700 		JBrowse link
G DISC1 DISC1 scaffold protein acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4837265|PMID:20880836) MGI
Ensembl		 PMID:20880836 GO_REF:0000107 MGI:4837265 NCBI chr 1:231,626,790...232,041,272
Ensembl chr 1:231,626,790...232,041,272 		JBrowse link
G EGF epidermal growth factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G FBXO22 F-box protein 22 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3840749|PMID:19319192) MGI
Ensembl		 PMID:19319192 GO_REF:0000107 MGI:3840749 NCBI chr15:75,903,878...75,942,511
Ensembl chr15:75,903,876...75,942,511 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 involved_in IEA
IMP
IDA		 (PMID:27238018)
(PMID:20208556)		 Ensembl
UniProt
BHF-UCL		 PMID:20208556 PMID:27238018 GO_REF:0000107 NCBI chr 4:152,320,544...152,536,092
Ensembl chr 4:152,320,544...152,536,092 		JBrowse link
G L3MBTL3 L3MBTL histone methyl-lysine binding protein 3 involved_in IMP (PMID:29691401) UniProt PMID:29691401 NCBI chr 6:130,018,581...130,141,438
Ensembl chr 6:130,013,699...130,141,449 		JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in ISS (PMID:8661146) ARUK-UCL PMID:8661146 NCBI chr 1:30,732,469...30,757,774
Ensembl chr 1:30,732,469...30,757,774 		JBrowse link
G MAGEF1 MAGE family member F1 involved_in IDA (PMID:29225034) UniProt PMID:29225034 NCBI chr 3:184,710,364...184,712,064
Ensembl chr 3:184,710,364...184,712,064 		JBrowse link
G PTEN phosphatase and tensin homolog involved_in IDA (PMID:21241890) BHF-UCL PMID:21241890 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,563...87,971,930 		JBrowse link
G PTK2 protein tyrosine kinase 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:27,310,506...27,459,391
Ensembl chr 8:27,311,482...27,459,391 		JBrowse link
G PYHIN1 pyrin and HIN domain family member 1 involved_in IMP
IDA		 (PMID:16479015)
(PMID:18247378)		 UniProt PMID:16479015 PMID:18247378 NCBI chr 1:158,931,552...158,990,870
Ensembl chr 1:158,930,796...158,977,059 		JBrowse link
G RNF139 ring finger protein 139 involved_in IMP (PMID:25239945) UniProt PMID:25239945 NCBI chr 8:124,474,880...124,488,618
Ensembl chr 8:124,474,880...124,488,618 		JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 involved_in IMP (PMID:21454619) CACAO PMID:21454619 NCBI chr 7:99,027,440...99,144,108
Ensembl chr 7:99,027,440...99,144,108 		JBrowse link
G SUMO3 small ubiquitin like modifier 3 acts_upstream_of_or_within ISO (MGI:3813414|PMID:18644859) MGI PMID:18644859 MGI:3813414 NCBI chr21:44,805,617...44,818,062
Ensembl chr21:44,805,617...44,818,779 		JBrowse link
G TRIM67 tripartite motif containing 67 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5427306|PMID:22337885) MGI
Ensembl		 PMID:22337885 GO_REF:0000107 MGI:5427306 NCBI chr 1:231,162,058...231,221,565
Ensembl chr 1:231,162,058...231,221,565 		JBrowse link
G VCP valosin containing protein involved_in ISO
IEA		 RGD
Ensembl		 PMID:16103111 GO_REF:0000107 RGD:1599730 NCBI chr 9:35,056,064...35,072,625
Ensembl chr 9:35,053,928...35,072,668 		JBrowse link
regulation of anaphase-promoting complex-dependent catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDK2 cyclin dependent kinase 2 involved_in TAS Reactome Reactome:R-HSA-176408 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789 		JBrowse link
G PLK1 polo like kinase 1 involved_in TAS Reactome Reactome:R-HSA-176408 NCBI chr16:23,678,889...23,690,367
Ensembl chr16:23,677,656...23,690,367 		JBrowse link
regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in IBA
IEA		 (PMID:21873635) GO_Central
Ensembl		 PMID:21873635 GO_REF:0000107 NCBI chr16:56,932,142...56,944,864
Ensembl chr16:56,932,142...56,944,864 		JBrowse link
regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G USP19 ubiquitin specific peptidase 19 involved_in IMP (PMID:25088257) ParkinsonsUK-UCL PMID:25088257 NCBI chr 3:49,108,050...49,120,823
Ensembl chr 3:49,108,046...49,120,938 		JBrowse link
regulation of proteasomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in IMP (PMID:28111074) UniProt PMID:28111074 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G BTRC beta-transducin repeat containing E3 ubiquitin protein ligase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3835892|PMID:19103752) MGI
Ensembl		 PMID:19103752 GO_REF:0000107 MGI:3835892 NCBI chr10:101,354,048...101,557,313
Ensembl chr10:101,354,033...101,557,321 		JBrowse link
G DLGAP1 DLG associated protein 1 involved_in ISO PMID:15496675 BHF-UCL PMID:15496675 RGD:8553458 NCBI chr18:3,496,032...4,455,307
Ensembl chr18:3,496,032...4,455,307 		JBrowse link
G DNAAF4 dynein axonemal assembly factor 4 involved_in IDA (PMID:19423554) UniProt PMID:19423554 NCBI chr15:55,417,755...55,508,234
Ensembl chr15:55,410,525...55,508,234 		JBrowse link
G EPM2A EPM2A glucan phosphatase, laforin acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5793002|PMID:27107699) MGI
Ensembl		 PMID:27107699 GO_REF:0000107 MGI:5793002 NCBI chr 6:145,383,353...145,736,023
Ensembl chr 6:145,382,535...145,736,023 		JBrowse link
G GPX1 glutathione peroxidase 1 involved_in IDA (PMID:12751788) BHF-UCL PMID:12751788 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G NFE2L1 NFE2 like bZIP transcription factor 1 acts_upstream_of_or_within ISO (MGI:6198859|PMID:29400713)
(MGI:5913760|PMID:27920251)		 MGI PMID:27920251 PMID:29400713 MGI:5913760 MGI:6198859 NCBI chr17:48,048,359...48,061,545
Ensembl chr17:48,048,329...48,061,545 		JBrowse link
G NUDT15 nudix hydrolase 15 involved_in IMP (PMID:19419956) UniProt PMID:19419956 NCBI chr13:48,037,726...48,052,755
Ensembl chr13:48,037,726...48,047,221 		JBrowse link
G PINK1 PTEN induced kinase 1 involved_in NAS (PMID:22078885) ParkinsonsUK-UCL PMID:22078885 NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511 		JBrowse link
G PITHD1 PITH domain containing 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:6392185|PMID:31915251) MGI
Ensembl		 PMID:31915251 GO_REF:0000107 MGI:6392185 NCBI chr 1:23,778,418...23,788,232
Ensembl chr 1:23,778,418...23,788,232 		JBrowse link
G PKD1 polycystin 1, transient receptor potential channel interacting acts_upstream_of_or_within
involved_in		 IDA
IEA		 (PMID:23001567) MGI
Ensembl		 PMID:23001567 GO_REF:0000107 NCBI chr16:2,088,708...2,135,898
Ensembl chr16:2,088,708...2,135,898 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in IDA (PMID:17565987) UniProt PMID:17565987 NCBI chr19:14,091,688...14,117,762
Ensembl chr19:14,091,688...14,118,084 		JBrowse link
G PSMD14 proteasome 26S subunit, non-ATPase 14 involved_in IMP (PMID:18162577) UniProt PMID:18162577 NCBI chr 2:161,308,425...161,411,717
Ensembl chr 2:161,308,425...161,411,717 		JBrowse link
G PSME1 proteasome activator subunit 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:24,136,194...24,138,962
Ensembl chr14:24,136,163...24,138,967 		JBrowse link
G PSME2 proteasome activator subunit 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:24,143,365...24,146,610
Ensembl chr14:24,143,362...24,147,570 		JBrowse link
G PSME3 proteasome activator subunit 3 involved_in IDA
IBA		 (PMID:18309296)
(PMID:21873635)		 UniProt
GO_Central		 PMID:18309296 PMID:21873635 NCBI chr17:42,833,397...42,843,760
Ensembl chr17:42,824,385...42,843,760 		JBrowse link
G RHBDF1 rhomboid 5 homolog 1 involved_in IDA (PMID:21439629) UniProt PMID:21439629 NCBI chr16:58,059...76,360
Ensembl chr16:58,059...76,355 		JBrowse link
G TMF1 TATA element modulatory factor 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:69,019,827...69,052,333
Ensembl chr 3:69,019,827...69,052,339 		JBrowse link
G UBB ubiquitin B acts_upstream_of_or_within IDA (PMID:17571083) MGI PMID:17571083 NCBI chr17:16,380,779...16,382,745
Ensembl chr17:16,380,798...16,382,745 		JBrowse link
G UCHL5 ubiquitin C-terminal hydrolase L5 involved_in IMP (PMID:18162577) UniProt PMID:18162577 NCBI chr 1:193,012,254...193,060,076
Ensembl chr 1:193,012,250...193,060,080 		JBrowse link
G USP14 ubiquitin specific peptidase 14 involved_in IMP
IBA		 (PMID:18162577)
(PMID:21873635)		 UniProt
GO_Central		 PMID:18162577 PMID:21873635 NCBI chr18:158,557...214,629
Ensembl chr18:158,383...214,629 		JBrowse link
regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARAF A-Raf proto-oncogene, serine/threonine kinase involved_in IMP (PMID:22609986) UniProt PMID:22609986 NCBI chr  X:47,561,205...47,571,908
Ensembl chr  X:47,561,205...47,571,908 		JBrowse link
G COMMD1 copper metabolism domain containing 1 involved_in IMP
IBA		 (PMID:17183367)
(PMID:21873635)		 UniProt
GO_Central		 PMID:17183367 PMID:21873635 NCBI chr 2:61,888,391...62,136,058
Ensembl chr 2:61,888,724...62,147,247 		JBrowse link
G DDA1 DET1 and DDB1 associated 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr19:17,309,563...17,323,298
Ensembl chr19:17,309,518...17,323,298 		JBrowse link
G DESI1 desumoylating isopeptidase 1 involved_in IDA (PMID:29666234) UniProt PMID:29666234 NCBI chr22:41,598,028...41,621,043
Ensembl chr22:41,598,028...41,621,043 		JBrowse link
G FOXF2 forkhead box F2 involved_in IDA (PMID:29374064) UniProt PMID:29374064 NCBI chr 6:1,389,576...1,395,603
Ensembl chr 6:1,389,576...1,395,603 		JBrowse link
G GLMN glomulin, FKBP associated protein acts_upstream_of_or_within IMP (PMID:22405651) MGI PMID:22405651 NCBI chr 1:92,246,402...92,370,844
Ensembl chr 1:92,246,402...92,298,987 		JBrowse link
G GNA12 G protein subunit alpha 12 involved_in IEA
IMP		 (PMID:22609986) Ensembl
UniProt		 PMID:22609986 GO_REF:0000107 NCBI chr 7:2,728,105...2,844,308
Ensembl chr 7:2,728,105...2,844,308 		JBrowse link
G RAD23A RAD23 homolog A, nucleotide excision repair protein involved_in IDA
IEA		 (PMID:12643283) UniProt PMID:12643283 GO_REF:0000117 NCBI chr19:12,945,862...12,953,642
Ensembl chr19:12,945,855...12,953,642 		JBrowse link
G RAD23B RAD23 homolog B, nucleotide excision repair protein involved_in IDA
IEA		 (PMID:19435460) UniProt PMID:19435460 GO_REF:0000117 NCBI chr 9:107,283,279...107,332,194
Ensembl chr 9:107,283,137...107,332,192 		JBrowse link
G UBE2K ubiquitin conjugating enzyme E2 K acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3806928|PMID:18710920) MGI
Ensembl		 PMID:18710920 GO_REF:0000107 MGI:3806928 NCBI chr 4:39,698,136...39,782,792
Ensembl chr 4:39,698,109...39,782,792 		JBrowse link
G UBQLN1 ubiquilin 1 involved_in IEA UniProt GO_REF:0000117 NCBI chr 9:83,659,968...83,707,958
Ensembl chr 9:83,659,968...83,707,958 		JBrowse link
G UBQLN2 ubiquilin 2 involved_in IEA UniProt GO_REF:0000117 NCBI chr  X:56,563,627...56,567,868
Ensembl chr  X:56,563,627...56,567,868 		JBrowse link
G UBQLN3 ubiquilin 3 involved_in IEA UniProt GO_REF:0000117 NCBI chr11:5,507,300...5,509,957
Ensembl chr11:5,507,300...5,509,958 		JBrowse link
G UBQLN4 ubiquilin 4 involved_in IDA
IEA
IMP		 (PMID:27113755)
(PMID:15280365)		 UniProt PMID:15280365 PMID:27113755 GO_REF:0000117 NCBI chr 1:156,031,247...156,053,798
Ensembl chr 1:156,035,299...156,053,798 		JBrowse link
G UFL1 UFM1 specific ligase 1 involved_in
acts_upstream_of_or_within		 IBA
IMP		 (PMID:21873635)
(PMID:20228063)		 GO_Central
MGI		 PMID:20228063 PMID:21873635 NCBI chr 6:96,521,806...96,555,276
Ensembl chr 6:96,521,595...96,555,276 		JBrowse link
G WNT10B Wnt family member 10B acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3820325|PMID:19056892) MGI
Ensembl		 PMID:19056892 GO_REF:0000107 MGI:3820325 NCBI chr12:48,965,340...48,971,735
Ensembl chr12:48,965,340...48,971,735 		JBrowse link
G XPO1 exportin 1 involved_in IDA (PMID:29666234) UniProt PMID:29666234 NCBI chr 2:61,477,849...61,538,612
Ensembl chr 2:61,476,032...61,538,741 		JBrowse link
regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G L3MBTL3 L3MBTL histone methyl-lysine binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:130,018,581...130,141,438
Ensembl chr 6:130,013,699...130,141,449 		JBrowse link
G LATS1 large tumor suppressor kinase 1 involved_in IMP (PMID:28068668) UniProt PMID:28068668 NCBI chr 6:149,658,153...149,718,101
Ensembl chr 6:149,658,153...149,718,105 		JBrowse link
G NUB1 negative regulator of ubiquitin like proteins 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:151,341,812...151,378,449
Ensembl chr 7:151,341,772...151,378,449 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in IDA (PMID:19880522) UniProt PMID:19880522 NCBI chr 8:27,310,506...27,459,391
Ensembl chr 8:27,311,482...27,459,391 		JBrowse link
G TMEM168 transmembrane protein 168 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:6511555|PMID:32175648) MGI
Ensembl		 PMID:32175648 GO_REF:0000107 MGI:6511555 NCBI chr 7:112,762,377...112,790,393
Ensembl chr 7:112,762,377...112,790,423 		JBrowse link
G UBE3A ubiquitin protein ligase E3A involved_in IMP
IBA		 (PMID:24728990)
(PMID:21873635)		 UniProt
GO_Central		 PMID:21873635 PMID:24728990 NCBI chr15:25,333,728...25,439,056
Ensembl chr15:25,333,728...25,439,051 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19600
    metabolic process 12946
      primary metabolic process 9363
        protein metabolic process 5613
          regulation of protein metabolic process 2807
            regulation of proteolysis 798
              regulation of proteolysis involved in protein catabolic process 250
                negative regulation of proteolysis involved in protein catabolic process + 75
                positive regulation of proteolysis involved in protein catabolic process + 147
                regulation of proteasomal protein catabolic process + 210
                regulation of proteolysis associated with antigen processing and presentation + 0
                regulation of ubiquitin-dependent protein catabolic process + 188
Path 2
Term Annotations click to browse term
  biological_process 19600
    metabolic process 12946
      nitrogen compound metabolic process 8748
        organonitrogen compound metabolic process 6718
          protein metabolic process 5613
            proteolysis 1900
              regulation of proteolysis 798
                regulation of proteolysis involved in protein catabolic process 250
                  negative regulation of proteolysis involved in protein catabolic process + 75
                  positive regulation of proteolysis involved in protein catabolic process + 147
                  regulation of proteasomal protein catabolic process + 210
                  regulation of proteolysis associated with antigen processing and presentation + 0
                  regulation of ubiquitin-dependent protein catabolic process + 188
paths to the root