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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of proteolysis involved in protein catabolic process
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Accession:GO:1903050 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of proteolysis involved in cellular catabolic process.
Comment:overexpression of cathepsin C propeptide significantly increased the degradation of intestinal alkaline phosphatase (IAP)
Synonyms:exact_synonym: regulation of peptidolysis involved in cellular protein catabolic process;   regulation of peptidolysis involved in cellular protein catabolism;   regulation of proteolysis involved in cellular protein catabolic process
 related_synonym: regulation of peptidolysis during cellular protein catabolic process;   regulation of peptidolysis during cellular protein catabolism;   regulation of proteolysis during cellular protein catabolic process;   regulation of proteolysis during cellular protein catabolism


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negative regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:56,432,688...56,451,438
Ensembl chr20:56,441,724...56,450,215 		JBrowse link
G SVIP small VCP interacting protein involved_in ISO (PMID:17872946) UniProt PMID:17872946 NCBI chr21:44,408,467...44,418,160
Ensembl chr21:44,408,474...44,415,739 		JBrowse link
G USP14 ubiquitin specific peptidase 14 involved_in ISO (PMID:19135427) ParkinsonsUK-UCL PMID:19135427 NCBI chr 7:67,035,774...67,080,082
Ensembl chr 7:67,035,843...67,079,465 		JBrowse link
negative regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP11 aquaporin 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:21,170,760...21,185,709
Ensembl chr21:21,171,008...21,185,429 		JBrowse link
G UBXN1 UBX domain protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:53,977,937...53,982,108
Ensembl chr18:53,978,062...53,982,111 		JBrowse link
G USP25 ubiquitin specific peptidase 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chr31:12,555,614...12,692,765
Ensembl chr31:12,555,595...12,691,694 		JBrowse link
negative regulation of proteasomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALAD aminolevulinate dehydratase involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:67,736,643...67,752,399
Ensembl chr11:67,741,390...67,752,321 		JBrowse link
G F8A1 coagulation factor VIII associated 1 involved_in ISO (PMID:27815841) UniProt PMID:27815841 NCBI chr  X:122,914,362...122,916,199 JBrowse link
G GABARAPL2 GABA type A receptor associated protein like 2 involved_in ISO (PMID:21669198) BHF-UCL PMID:21669198 NCBI chr 5:75,230,214...75,240,724
Ensembl chr 5:75,230,243...75,240,730 		JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 involved_in ISO (MGI:6148636|PMID:17517623) ARUK-UCL PMID:17517623 MGI:6148636 RGD:13514081 NCBI chr12:12,658,415...12,664,945
Ensembl chr12:12,660,008...12,664,940 		JBrowse link
G LAMP3 lysosomal associated membrane protein 3 involved_in ISO (PMID:25681212) ParkinsonsUK-UCL PMID:25681212 NCBI chr34:16,092,172...16,126,563 JBrowse link
G MARCHF7 membrane associated ring-CH-type finger 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:5,481,449...5,533,139
Ensembl chr36:5,481,456...5,531,957 		JBrowse link
G OPHN1 oligophrenin 1 involved_in ISO (MGI:5303043|PMID:21874017) UniProt PMID:21874017 MGI:5303043 NCBI chr  X:52,418,390...52,983,155
Ensembl chr  X:52,455,373...52,982,244 		JBrowse link
G PRKCG protein kinase C gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:103,295,110...103,312,562 JBrowse link
G PSME3IP1 proteasome activator subunit 3 interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:59,185,238...59,220,515
Ensembl chr 2:59,186,349...59,220,515 		JBrowse link
G PSMF1 proteasome inhibitor subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:19,817,104...19,863,632
Ensembl chr24:19,819,055...19,859,586 		JBrowse link
G SCO1 synthesis of cytochrome C oxidase 1 acts_upstream_of_or_within ISO (MGI:5643882|PMID:25683716) MGI PMID:25683716 MGI:5643882 NCBI chr 5:34,957,358...34,971,684
Ensembl chr 5:34,957,785...34,971,661 		JBrowse link
G USP19 ubiquitin specific peptidase 19 involved_in ISO (MGI:5614537|PMID:25088257) ParkinsonsUK-UCL PMID:25088257 MGI:5614537 NCBI chr20:40,062,802...40,074,221
Ensembl chr20:40,064,599...40,074,082 		JBrowse link
negative regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG5 BAG cochaperone 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:71,318,730...71,324,743
Ensembl chr 8:71,321,625...71,322,992 		JBrowse link
G BAG6 BAG cochaperone 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:1,126,730...1,141,978
Ensembl chr12:1,126,732...1,137,896 		JBrowse link
G CAMLG calcium modulating ligand involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:22,818,699...22,829,737
Ensembl chr11:22,818,743...22,829,736 		JBrowse link
G CCAR2 cell cycle and apoptosis regulator 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:34,660,026...34,674,129
Ensembl chr25:34,660,553...34,674,037 		JBrowse link
G CLEC16A C-type lectin domain containing 16A acts_upstream_of_or_within ISO (MGI:5603233|PMID:24949970) MGI PMID:24949970 MGI:5603233 NCBI chr 6:31,560,940...31,757,100
Ensembl chr 6:31,562,834...31,757,678 		JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:18,085,865...18,098,868
Ensembl chr24:18,084,725...18,097,157 		JBrowse link
G EIF3H eukaryotic translation initiation factor 3 subunit H involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:16,105,960...16,201,902
Ensembl chr13:16,105,990...16,341,153 		JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase involved_in IEA
IBA		 (PMID:21873635) Ensembl
GO_Central		 PMID:21873635 GO_REF:0000107 NCBI chr20:29,735,380...31,113,859
Ensembl chr20:30,356,572...31,113,859 		JBrowse link
G GIPC1 GIPC PDZ domain containing family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:48,144,076...48,155,069
Ensembl chr20:48,150,498...48,157,191 		JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 involved_in ISO (PMID:24613385) UniProt PMID:24613385 NCBI chr12:12,658,415...12,664,945
Ensembl chr12:12,660,008...12,664,940 		JBrowse link
G KLHL40 kelch like family member 40 acts_upstream_of_or_within ISO (MGI:5586592|PMID:24960163) MGI PMID:24960163 MGI:5586592 NCBI chr23:11,812,268...11,820,426
Ensembl chr23:11,813,550...11,820,420 		JBrowse link
G MAP1A microtubule associated protein 1A involved_in ISO (MGI:5703671|PMID:26609151) ARUK-UCL PMID:26609151 MGI:5703671 NCBI chr30:10,361,871...10,382,780
Ensembl chr30:10,361,909...10,381,376 		JBrowse link
G MTM1 myotubularin 1 acts_upstream_of_or_within ISO (MGI:5510937|PMID:23695157) MGI PMID:23695157 MGI:5510937 NCBI chr  X:118,820,644...118,917,166
Ensembl chr  X:118,820,494...118,916,368 		JBrowse link
G N4BP1 NEDD4 binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:66,544,665...66,565,858
Ensembl chr 2:66,544,677...66,561,560 		JBrowse link
G NOP53 NOP53 ribosome biogenesis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:108,307,039...108,315,732
Ensembl chr 1:108,307,042...108,316,495 		JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:55,821,227...55,857,597
Ensembl chr  X:55,821,234...55,855,502 		JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in ISO (PMID:17015834) ParkinsonsUK-UCL PMID:17015834 NCBI chr 5:61,576,219...61,592,325
Ensembl chr 5:61,576,069...61,592,303 		JBrowse link
G PBK PDZ binding kinase acts_upstream_of_or_within ISO (MGI:5293269|PMID:21715333) MGI PMID:21715333 MGI:5293269 NCBI chr25:29,751,805...29,781,806
Ensembl chr25:29,751,848...29,781,300 		JBrowse link
G PHF20L1 PHD finger protein 20 like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:29,260,381...29,338,345
Ensembl chr13:29,260,373...29,336,623 		JBrowse link
G PTGER1 prostaglandin E receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:48,156,055...48,159,838
Ensembl chr20:48,157,973...48,159,921 		JBrowse link
G RPL11 ribosomal protein L11 involved_in ISO (MGI:5897550|PMID:21804542) UniProt PMID:21804542 MGI:5897550 NCBI chr 2:75,781,210...75,785,614
Ensembl chr 2:75,781,091...75,785,605 		JBrowse link
G RYBP RING1 and YY1 binding protein involved_in ISO (PMID:27060496) UniProt PMID:27060496 NCBI chr20:19,650,936...19,732,987
Ensembl chr20:19,615,426...19,729,474 		JBrowse link
G SDCBP syndecan binding protein involved_in ISO (PMID:25893292) UniProt PMID:25893292 NCBI chr29:9,331,876...9,370,489 JBrowse link
G SENP1 SUMO specific peptidase 1 acts_upstream_of_or_within ISO (MGI:3818351|PMID:17981124) MGI PMID:17981124 MGI:3818351 NCBI chr27:6,664,750...6,719,257
Ensembl chr27:6,664,818...6,714,479 		JBrowse link
G SHH sonic hedgehog signaling molecule acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3624046|PMID:16611981) MGI
Ensembl		 PMID:16611981 GO_REF:0000107 MGI:3624046 NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903 		JBrowse link
G SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5310666|PMID:22285184) MGI
Ensembl		 PMID:22285184 GO_REF:0000107 MGI:5310666 NCBI chr20:41,165,593...41,337,237
Ensembl chr20:41,165,522...41,335,917 		JBrowse link
G TAF9 TATA-box binding protein associated factor 9 involved_in ISO (PMID:11278372) BHF-UCL PMID:11278372 NCBI chr 2:54,403,908...54,406,857
Ensembl chr 2:54,390,411...54,406,872 		JBrowse link
G TLK2 tousled like kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:10,686,424...10,804,885
Ensembl chr 9:10,687,293...10,803,963 		JBrowse link
G TTC36 tetratricopeptide repeat domain 36 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:6362140|PMID:31537781) MGI
Ensembl		 PMID:31537781 GO_REF:0000107 MGI:6362140 NCBI chr 5:15,207,400...15,211,905
Ensembl chr 5:15,207,403...15,211,853 		JBrowse link
G UBXN1 UBX domain protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:53,977,937...53,982,108
Ensembl chr18:53,978,062...53,982,111 		JBrowse link
G UCHL5 ubiquitin C-terminal hydrolase L5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:6,004,595...6,045,999
Ensembl chr38:6,004,659...6,113,714 		JBrowse link
G USP7 ubiquitin specific peptidase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:33,277,328...33,315,601
Ensembl chr 6:33,277,444...33,314,491 		JBrowse link
G USP9X ubiquitin specific peptidase 9 X-linked involved_in ISO (PMID:33378666) UniProt PMID:33378666 NCBI chr  X:35,522,873...35,676,086 JBrowse link
G WAC WW domain containing adaptor with coiled-coil involved_in ISO (PMID:22354037) BHF-UCL PMID:22354037 NCBI chr 2:17,504,949...17,588,037 JBrowse link
negative regulation of proteolysis involved in protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN2A cyclin dependent kinase inhibitor 2A acts_upstream_of_or_within
involved_in		 ISO (MGI:5468878|PMID:23277542)
(PMID:25217637)		 MGI
ParkinsonsUK-UCL		 PMID:23277542 PMID:25217637 MGI:5468878 NCBI chr11:41,223,316...41,226,056
Ensembl chr11:41,223,315...41,264,379 		JBrowse link
G EFNA1 ephrin A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:42,373,197...42,381,161
Ensembl chr 7:42,373,639...42,378,946 		JBrowse link
G EPHA4 EPH receptor A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:27,670,143...27,809,642
Ensembl chr37:27,677,566...27,809,646 		JBrowse link
negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PABPN1L PABPN1 like, cytoplasmic acts_upstream_of_or_within ISO (MGI:6509513|PMID:32558204) MGI PMID:32558204 MGI:6509513 NCBI chr 5:64,525,929...64,527,654 JBrowse link
G STYX serine/threonine/tyrosine interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:28,949,732...28,990,455
Ensembl chr 8:28,950,061...28,986,812 		JBrowse link
negative regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A acts_upstream_of_or_within ISO (MGI:4461099|PMID:20100865) MGI PMID:20100865 MGI:4461099 NCBI chr12:4,095,394...4,274,428
Ensembl chr12:4,095,490...4,272,654 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A acts_upstream_of_or_within
involved_in		 ISO (MGI:5468878|PMID:23277542)
(PMID:16173922), (PMID:18560357)		 MGI
UniProt		 PMID:16173922 PMID:18560357 PMID:23277542 MGI:5468878 NCBI chr11:41,223,316...41,226,056
Ensembl chr11:41,223,315...41,264,379 		JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 involved_in ISO (PMID:28031292) ARUK-UCL PMID:28031292 NCBI chr24:20,333,593...20,390,341 JBrowse link
G CSNK2A2 casein kinase 2 alpha 2 involved_in ISO (PMID:28031292) ARUK-UCL PMID:28031292 NCBI chr 2:58,361,328...58,441,701
Ensembl chr 2:58,360,838...58,432,371 		JBrowse link
G HFE homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:24,031,479...24,038,922
Ensembl chr35:24,031,387...24,042,413 		JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:9,066,957...9,256,916
Ensembl chr16:9,066,970...9,244,526 		JBrowse link
G PDCL3 phosducin like 3 acts_upstream_of_or_within ISO (PMID:23792958) MGI PMID:23792958 NCBI chr10:42,214,127...42,223,986
Ensembl chr10:42,215,120...42,223,906 		JBrowse link
G PML PML nuclear body scaffold involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:37,232,337...37,278,434
Ensembl chr30:37,232,306...37,277,741 		JBrowse link
G PRMT6 protein arginine methyltransferase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:44,475,829...44,478,215
Ensembl chr 6:44,477,030...44,478,160 		JBrowse link
G PSEN1 presenilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:46,495,551...46,569,532
Ensembl chr 8:46,495,624...46,569,532 		JBrowse link
G PSEN2 presenilin 2 involved_in ISO (MGI:4887523|PMID:20208556) BHF-UCL PMID:20208556 MGI:4887523 NCBI chr 7:38,147,157...38,163,023
Ensembl chr 7:38,147,173...38,166,722 		JBrowse link
G QRICH2 glutamine rich 2 involved_in ISO (PMID:30683861)
(MGI:6277293|PMID:30683861)		 UniProt PMID:30683861 MGI:6277293 NCBI chr 9:4,395,501...4,408,302
Ensembl chr 9:4,374,650...4,408,299 		JBrowse link
G RPL11 ribosomal protein L11 involved_in ISO (PMID:18560357) CAFA PMID:18560357 NCBI chr 2:75,781,210...75,785,614
Ensembl chr 2:75,781,091...75,785,605 		JBrowse link
G RPL23 ribosomal protein L23 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:23,397,143...23,403,060
Ensembl chr 9:23,262,282...23,403,054 		JBrowse link
G RPL5 ribosomal protein L5 involved_in ISO (PMID:18560357) CAFA PMID:18560357 NCBI chr 6:56,207,171...56,216,030
Ensembl chr 6:56,207,173...56,215,956 		JBrowse link
G RPS7 ribosomal protein S7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:2,139,011...2,143,160
Ensembl chr17:2,138,779...2,143,178 		JBrowse link
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:56,432,688...56,451,438
Ensembl chr20:56,441,724...56,450,215 		JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4355593|PMID:19684112) MGI
Ensembl		 PMID:19684112 GO_REF:0000107 MGI:4355593 NCBI chr28:14,992,989...15,115,499
Ensembl chr28:14,992,618...15,112,389 		JBrowse link
G TAF1 TATA-box binding protein associated factor 1 involved_in ISO (PMID:17237821) ParkinsonsUK-UCL PMID:17237821 NCBI chr  X:55,693,091...55,764,268
Ensembl chr  X:55,693,194...55,763,683 		JBrowse link
G WNT1 Wnt family member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3628833|PMID:16601693) MGI
Ensembl		 PMID:16601693 GO_REF:0000107 MGI:3628833 NCBI chr27:5,588,151...5,592,254
Ensembl chr27:5,574,940...5,592,060 		JBrowse link
positive regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCAP31 B cell receptor associated protein 31 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:121,515,417...121,550,373
Ensembl chr  X:121,507,084...121,545,263 		JBrowse link
G CAV1 caveolin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:55,458,934...55,494,563
Ensembl chr14:55,461,048...55,492,935 		JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:59,388,492...59,400,028
Ensembl chr 2:59,388,494...59,400,003 		JBrowse link
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:56,432,688...56,451,438
Ensembl chr20:56,441,724...56,450,215 		JBrowse link
G UBQLN1 ubiquilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:75,767,345...75,812,278
Ensembl chr 1:75,767,188...75,838,051 		JBrowse link
G UBQLN2 ubiquilin 2 involved_in ISO (PMID:18307982) UniProt PMID:18307982 NCBI chr  X:47,860,923...47,864,282 JBrowse link
positive regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATXN3 ataxin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:1,318,440...1,354,814
Ensembl chr 8:1,247,155...1,354,720 		JBrowse link
G BAG6 BAG cochaperone 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:1,126,730...1,141,978
Ensembl chr12:1,126,732...1,137,896 		JBrowse link
G FBXW8 F-box and WD repeat domain containing 8 involved_in IEA InterPro GO_REF:0000002 NCBI chr26:13,520,605...13,640,975
Ensembl chr26:13,412,189...13,638,258 		JBrowse link
G RNF185 ring finger protein 185 involved_in ISO (PMID:27485036) UniProt PMID:27485036 NCBI chr26:24,146,172...24,177,747
Ensembl chr26:24,146,005...24,240,653 		JBrowse link
G RNFT1 ring finger protein, transmembrane 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 9:34,430,119...34,442,760
Ensembl chr 9:34,335,554...34,442,374 		JBrowse link
G RNFT2 ring finger protein, transmembrane 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr26:13,410,393...13,500,716
Ensembl chr26:13,412,189...13,638,258 		JBrowse link
G TMEM259 transmembrane protein 259 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:57,695,004...57,703,650
Ensembl chr20:57,695,002...57,749,891 		JBrowse link
G TMEM67 transmembrane protein 67 ISO RGD PMID:19815549 RGD:8554391 NCBI chr29:38,655,531...38,715,774
Ensembl chr29:38,654,733...38,720,559 		JBrowse link
G TRIP11 thyroid hormone receptor interactor 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:1,244,104...1,314,251
Ensembl chr 8:1,247,155...1,354,720 		JBrowse link
G USP13 ubiquitin specific peptidase 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:13,059,099...13,175,980
Ensembl chr34:13,059,092...13,171,234 		JBrowse link
G WFS1 wolframin ER transmembrane glycoprotein involved_in ISO (MGI:4999711|PMID:19911006) MGI PMID:19911006 MGI:4999711 NCBI chr13:38,451,722...38,466,481
Ensembl chr13:38,451,710...38,475,827 		JBrowse link
positive regulation of proteasomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG2 BAG cochaperone 2 involved_in ISO (MGI:6148635|PMID:19228967) ARUK-UCL PMID:19228967 MGI:6148635 NCBI chr12:24,353,549...24,369,190
Ensembl chr12:24,353,663...24,368,350 		JBrowse link
G DAB2IP DAB2 interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:60,725,887...60,918,242
Ensembl chr 9:60,726,809...60,918,139 		JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:18,085,865...18,098,868
Ensembl chr24:18,084,725...18,097,157 		JBrowse link
G ECSCR endothelial cell surface expressed chemotaxis and apoptosis regulator acts_upstream_of_or_within ISO (PMID:19416853) MGI PMID:19416853 NCBI chr 2:34,763,814...34,773,491 JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:50,187,579...50,417,188
Ensembl chr15:50,189,240...50,417,195 		JBrowse link
G FMR1 Fragile X messenger ribonucleoprotein 1 involved_in ISO (MGI:5770038|PMID:24709664) UniProt PMID:24709664 MGI:5770038 NCBI chr  X:116,249,079...116,287,008
Ensembl chr  X:116,249,142...116,321,439 		JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr31:29,777,154...29,777,839
Ensembl chr31:29,581,658...29,777,525 		JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in IEA Ensembl GO_REF:0000107
G LOC100687152 26S proteasome regulatory subunit 6A-like involved_in IEA GOC GO_REF:0000108 NCBI chr  X:51,797,241...51,798,636 JBrowse link
G LOC478703 proteasome (prosome, macropain) 26S subunit, ATPase, 1 pseudogene involved_in IEA GOC GO_REF:0000108 NCBI chr35:4,052,049...4,053,618 JBrowse link
G NUPR1 nuclear protein 1, transcriptional regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:18,222,367...18,224,015
Ensembl chr 6:18,222,515...18,224,014 		JBrowse link
G OSBPL7 oxysterol binding protein like 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:24,139,641...24,156,692
Ensembl chr 9:24,139,630...24,154,924 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:49,886,887...51,201,930
Ensembl chr 1:49,889,005...51,201,764 		JBrowse link
G PSMC1 proteasome 26S subunit, ATPase 1 involved_in IEA GOC GO_REF:0000108 NCBI chr 8:61,272,363...61,285,886
Ensembl chr 8:61,272,363...61,285,886 		JBrowse link
G PSMC2 proteasome 26S subunit, ATPase 2 involved_in IEA GOC GO_REF:0000108 NCBI chr18:16,845,593...16,859,010
Ensembl chr18:16,845,594...16,858,911 		JBrowse link
G PSMC3 proteasome 26S subunit, ATPase 3 involved_in IEA GOC GO_REF:0000108 NCBI chr18:42,212,083...42,218,958 JBrowse link
G PSMC4 proteasome 26S subunit, ATPase 4 involved_in IEA GOC GO_REF:0000108 NCBI chr 1:113,548,351...113,557,725
Ensembl chr 1:113,548,373...113,557,630 		JBrowse link
G PSMC5 proteasome 26S subunit, ATPase 5 involved_in IEA GOC GO_REF:0000108 NCBI chr 9:11,783,422...11,787,624
Ensembl chr 9:11,783,466...11,787,617 		JBrowse link
G PSMC6 proteasome 26S subunit, ATPase 6 involved_in IEA GOC GO_REF:0000108 NCBI chr 8:28,914,302...28,947,854 JBrowse link
G RNF40 ring finger protein 40 ISO RGD PMID:12121982 RGD:633892 NCBI chr 6:17,402,022...17,414,494
Ensembl chr 6:17,402,908...17,414,362 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:34,783,947...34,792,204
Ensembl chr 2:34,784,232...34,789,072 		JBrowse link
G TMTC3 transmembrane O-mannosyltransferase targeting cadherins 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:29,280,423...29,350,449
Ensembl chr15:29,298,078...29,350,553 		JBrowse link
G XBP1 X-box binding protein 1 acts_upstream_of_or_within ISO (MGI:4946566|PMID:21317886) MGI PMID:21317886 MGI:4946566 NCBI chr26:22,162,675...22,168,149
Ensembl chr26:22,163,222...22,168,105 		JBrowse link
positive regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3589701|PMID:15937334) MGI
Ensembl		 PMID:15937334 GO_REF:0000107 MGI:3589701 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193 		JBrowse link
G ATG7 autophagy related 7 acts_upstream_of_or_within ISO (MGI:5465208|PMID:23152632) MGI PMID:23152632 MGI:5465208 NCBI chr20:6,916,354...7,154,849
Ensembl chr20:6,916,515...7,154,800 		JBrowse link
G AURKA aurora kinase A acts_upstream_of_or_within ISO (MGI:3697244|PMID:17060449) MGI PMID:17060449 MGI:3697244 NCBI chr24:41,585,483...41,604,875
Ensembl chr24:41,585,518...41,604,791 		JBrowse link
G AXIN1 axin 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3628833|PMID:16601693) MGI
Ensembl		 PMID:16601693 GO_REF:0000107 MGI:3628833 NCBI chr 6:40,155,797...40,218,330
Ensembl chr 6:40,158,244...40,218,343 		JBrowse link
G BAG2 BAG cochaperone 2 NOT|involved_in ISO (MGI:6148635|PMID:19228967) ARUK-UCL PMID:19228967 MGI:6148635 NCBI chr12:24,353,549...24,369,190
Ensembl chr12:24,353,663...24,368,350 		JBrowse link
G BBS7 Bardet-Biedl syndrome 7 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:22302990) MGI
Ensembl		 PMID:22302990 GO_REF:0000107 NCBI chr19:18,280,487...18,319,128
Ensembl chr19:18,280,520...18,315,825 		JBrowse link
G CBFA2T3 CBFA2/RUNX1 partner transcriptional co-repressor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:64,432,291...64,518,905
Ensembl chr 5:64,431,843...64,519,528 		JBrowse link
G CHFR checkpoint with forkhead and ring finger domains acts_upstream_of_or_within ISO (MGI:5310666|PMID:22285184) MGI PMID:22285184 MGI:5310666 NCBI chr26:251,369...324,699
Ensembl chr26:294,909...324,696 		JBrowse link
G CLU clusterin involved_in ISS
IBA
IEA		 (PMID:21873635) UniProt
GO_Central
Ensembl		 PMID:21873635 GO_REF:0000024 GO_REF:0000107 NCBI chr25:29,982,811...29,999,565
Ensembl chr25:29,982,811...29,999,563 		JBrowse link
G COP1 COP1 E3 ubiquitin ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:23,320,483...23,565,093
Ensembl chr 7:23,277,209...23,563,397 		JBrowse link
G CSNK1A1 casein kinase 1 alpha 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:59,435,530...59,485,591
Ensembl chr 4:59,435,764...59,483,475 		JBrowse link
G CSNK1D casein kinase 1 delta involved_in ISO (MGI:3849793|PMID:19414593) UniProt PMID:19414593 MGI:3849793 NCBI chr 9:83,395...110,309
Ensembl chr 9:73,215...110,269 		JBrowse link
G CSNK1E casein kinase 1 epsilon involved_in ISO (MGI:3849793|PMID:19414593) UniProt PMID:19414593 MGI:3849793 NCBI chr10:26,386,646...26,412,429
Ensembl chr10:26,393,033...26,411,624 		JBrowse link
G DAB2 DAB adaptor protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:69,625,874...69,648,349
Ensembl chr 4:69,625,527...69,648,321 		JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:18,085,865...18,098,868
Ensembl chr24:18,084,725...18,097,157 		JBrowse link
G DET1 DET1 partner of COP1 E3 ubiquitin ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:51,725,931...51,765,487
Ensembl chr 3:51,725,926...51,775,185 		JBrowse link
G DNAJB2 DnaJ heat shock protein family (Hsp40) member B2 involved_in ISO (PMID:15936278) BHF-UCL PMID:15936278 NCBI chr37:25,826,496...25,834,011
Ensembl chr37:25,827,713...25,833,144 		JBrowse link
G DVL1 dishevelled segment polarity protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:56,507,803...56,519,382
Ensembl chr 5:56,507,739...56,519,491 		JBrowse link
G FBXO22 F-box protein 22 acts_upstream_of_or_within ISO (MGI:3840749|PMID:19319192) MGI PMID:19319192 MGI:3840749 NCBI chr30:40,100,768...40,127,708
Ensembl chr30:40,101,540...40,189,159 		JBrowse link
G GABARAP GABA type A receptor-associated protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,207,879...32,209,976
Ensembl chr 5:32,207,887...32,209,908 		JBrowse link
G GBA1 glucosylceramidase beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:42,317,704...42,322,285
Ensembl chr 7:42,317,862...42,322,864 		JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3695876|PMID:17189825) MGI
Ensembl		 PMID:17189825 GO_REF:0000107 MGI:3695876 NCBI chr12:20,999,815...21,047,779
Ensembl chr12:21,000,792...21,047,779 		JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:112,129,116...112,138,714
Ensembl chr 1:112,103,825...112,138,559 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5437589|PMID:22660580) MGI
Ensembl		 PMID:22660580 GO_REF:0000107 MGI:5437589 NCBI chr33:23,458,369...23,659,878
Ensembl chr33:23,463,767...23,659,666 		JBrowse link
G HSP70 heat shock protein 70 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:1,285,282...1,287,670 JBrowse link
G HSPBP1 HSPA (Hsp70) binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:102,389,438...102,402,578
Ensembl chr 1:102,389,608...102,402,380 		JBrowse link
G IL33 interleukin 33 acts_upstream_of_or_within ISO (MGI:5437589|PMID:22660580) MGI PMID:22660580 MGI:5437589 NCBI chr11:27,219,878...27,256,723
Ensembl chr11:27,219,878...27,256,721 		JBrowse link
G KLHL40 kelch like family member 40 involved_in ISO (MGI:5700633|PMID:25940086) UniProt PMID:25940086 MGI:5700633 NCBI chr23:11,812,268...11,820,426
Ensembl chr23:11,813,550...11,820,420 		JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:13,282,824...13,420,917
Ensembl chr27:13,283,756...13,420,870 		JBrowse link
G MDM2 MDM2 proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:10,936,288...10,963,118
Ensembl chr10:10,893,719...10,962,596 		JBrowse link
G NKD2 NKD inhibitor of WNT signaling pathway 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:11,447,895...11,468,067
Ensembl chr34:11,447,888...11,459,509 		JBrowse link
G NOP53 NOP53 ribosome biogenesis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:108,307,039...108,315,732
Ensembl chr 1:108,307,042...108,316,495 		JBrowse link
G NUB1 negative regulator of ubiquitin like proteins 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:15,355,237...15,382,284
Ensembl chr16:15,352,476...15,381,095 		JBrowse link
G PABIR1 PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 involved_in ISO (PMID:27588481) UniProt PMID:27588481 NCBI chr 1:88,580,008...88,587,037 JBrowse link
G PIAS1 protein inhibitor of activated STAT 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:32,116,363...32,232,530
Ensembl chr30:32,119,311...32,228,945 		JBrowse link
G PLK1 polo like kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:22,165,338...22,176,847
Ensembl chr 6:22,165,338...22,176,441 		JBrowse link
G PLK2 polo like kinase 2 ISO RGD PMID:18723513 RGD:7241135 NCBI chr 2:45,359,865...45,365,496
Ensembl chr 2:45,360,374...45,367,441 		JBrowse link
G PRICKLE1 prickle planar cell polarity protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:11,327,086...11,437,799
Ensembl chr27:11,426,647...11,437,303 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:49,886,887...51,201,930
Ensembl chr 1:49,889,005...51,201,764 		JBrowse link
G PSEN1 presenilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:46,495,551...46,569,532
Ensembl chr 8:46,495,624...46,569,532 		JBrowse link
G PSEN2 presenilin 2 involved_in ISO (MGI:4887523|PMID:20208556) BHF-UCL PMID:20208556 MGI:4887523 NCBI chr 7:38,147,157...38,163,023
Ensembl chr 7:38,147,173...38,166,722 		JBrowse link
G PSMD10 proteasome 26S subunit, non-ATPase 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:81,625,288...81,632,175
Ensembl chr  X:81,625,141...81,632,129 		JBrowse link
G RACK1 receptor for activated C kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:426,734...431,087
Ensembl chr11:426,215...431,089 		JBrowse link
G RAD23A RAD23 homolog A, nucleotide excision repair protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:49,244,330...49,250,058
Ensembl chr20:49,241,358...49,250,039 		JBrowse link
G RBX1 ring-box 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:24,265,733...24,280,253
Ensembl chr10:24,266,408...24,280,235 		JBrowse link
G RCHY1 ring finger and CHY zinc finger domain containing 1 involved_in ISO (PMID:19483087) UniProt PMID:19483087 NCBI chr32:67,136...94,053
Ensembl chr32:67,509...93,987 		JBrowse link
G RNF180 ring finger protein 180 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3819024|PMID:18363970), (MGI:5505713|PMID:23926250) MGI
Ensembl		 PMID:18363970 PMID:23926250 GO_REF:0000107 MGI:3819024 MGI:5505713 NCBI chr 2:50,166,987...50,353,694
Ensembl chr 2:50,197,137...50,352,946 		JBrowse link
G SH3RF2 SH3 domain containing ring finger 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:40,380,313...40,514,211
Ensembl chr 2:40,380,218...40,510,853 		JBrowse link
G SIRT2 sirtuin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:114,224,922...114,235,041
Ensembl chr 1:114,224,900...114,234,583 		JBrowse link
G SMAD7 SMAD family member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:79,706,485...79,734,673
Ensembl chr 7:79,706,705...79,734,749 		JBrowse link
G SOCS4 suppressor of cytokine signaling 4 involved_in IEA InterPro GO_REF:0000002 NCBI chr 8:30,892,663...30,898,896 JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr10:48,916,446...48,977,183
Ensembl chr10:48,972,842...48,974,452 		JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:39,893,492...39,895,385
Ensembl chr 6:39,893,670...39,897,573 		JBrowse link
G SUMO1 small ubiquitin like modifier 1 involved_in ISO (PMID:18408734) UniProt PMID:18408734 NCBI chr37:11,199,937...11,229,743
Ensembl chr37:11,200,590...11,229,754 		JBrowse link
G SUMO2 small ubiquitin like modifier 2 involved_in ISO (PMID:18408734) UniProt PMID:18408734 NCBI chr 9:5,298,315...5,311,184
Ensembl chr 9:5,298,340...5,311,184 		JBrowse link
G TAF1 TATA-box binding protein associated factor 1 involved_in ISO (PMID:15053879) BHF-UCL PMID:15053879 NCBI chr  X:55,693,091...55,764,268
Ensembl chr  X:55,693,194...55,763,683 		JBrowse link
G TRIB1 tribbles pseudokinase 1 involved_in ISO (MGI:4457446|PMID:20410507) BHF-UCL PMID:20410507 MGI:4457446 NCBI chr13:23,337,788...23,346,304
Ensembl chr13:23,337,788...23,346,304 		JBrowse link
G TRIB2 tribbles pseudokinase 2 involved_in IBA
IEA		 (PMID:21873635) GO_Central
Ensembl		 PMID:21873635 GO_REF:0000107 NCBI chr17:9,225,598...9,251,826
Ensembl chr17:9,226,017...9,249,821 		JBrowse link
G UBE2V2 ubiquitin conjugating enzyme E2 V2 ISO RGD PMID:12750002 RGD:1299567 NCBI chr29:307,502...359,058
Ensembl chr29:307,525...357,962 		JBrowse link
G USP5 ubiquitin specific peptidase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:38,158,850...38,172,689
Ensembl chr27:38,158,834...38,172,071 		JBrowse link
G VCP valosin containing protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:51,636,986...51,651,749
Ensembl chr11:51,637,411...51,651,714 		JBrowse link
G ZER1 zyg-11 related cell cycle regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:54,842,607...54,873,336
Ensembl chr 9:54,842,317...54,871,717 		JBrowse link
G ZFAND2A zinc finger AN1-type containing 2A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3663213|PMID:16973439) MGI
Ensembl		 PMID:16973439 GO_REF:0000107 MGI:3663213 NCBI chr 6:15,725,903...15,736,450
Ensembl chr 6:15,726,076...15,883,451 		JBrowse link
G ZYG11B zyg-11 family member B, cell cycle regulator involved_in ISO (PMID:31273098) UniProt PMID:31273098 NCBI chr15:8,595,200...8,681,668
Ensembl chr15:8,597,738...8,681,364 		JBrowse link
positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLK3 polo like kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:15,519,042...15,523,960
Ensembl chr15:15,519,026...15,524,230 		JBrowse link
G SIRT2 sirtuin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:114,224,922...114,235,041
Ensembl chr 1:114,224,900...114,234,583 		JBrowse link
positive regulation of proteolysis involved in protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP5IF1 ATP synthase inhibitory factor subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:72,188,562...72,191,344
Ensembl chr 2:72,188,266...72,191,326 		JBrowse link
G CTSC cathepsin C involved_in ISO PMID:18307834 ParkinsonsUK-UCL PMID:18307834 RGD:8661625 NCBI chr21:11,659,296...11,692,957
Ensembl chr21:11,659,292...11,692,816 		JBrowse link
G GBA1 glucosylceramidase beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:42,317,704...42,322,285
Ensembl chr 7:42,317,862...42,322,864 		JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in ISO (MGI:5444793|PMID:22949502) ARUK-UCL PMID:22949502 MGI:5444793 NCBI chr 2:70,188,382...70,215,361
Ensembl chr 2:70,152,739...70,333,073 		JBrowse link
G RGN regucalcin ISO RGD PMID:1513338 RGD:9590188 NCBI chr  X:40,697,292...40,715,491
Ensembl chr  X:40,698,768...40,715,490 		JBrowse link
positive regulation of transcription factor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBXW8 F-box and WD repeat domain containing 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:13,520,605...13,640,975
Ensembl chr26:13,412,189...13,638,258 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 involved_in ISO (MGI:6148490|PMID:29153991) UniProt PMID:29153991 MGI:6148490 NCBI chr28:323,361...410,367
Ensembl chr28:368,513...406,401 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:1,443,528...1,480,501
Ensembl chr11:1,443,547...1,478,119 		JBrowse link
G SIRT6 sirtuin 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:55,412,989...55,424,944
Ensembl chr20:55,412,646...55,424,944 		JBrowse link
positive regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGBL4 AGBL carboxypeptidase 4 acts_upstream_of_or_within ISO (MGI:6149282|PMID:29593216) MGI PMID:29593216 MGI:6149282 NCBI chr15:11,056,440...12,435,428
Ensembl chr15:11,056,447...12,435,448 		JBrowse link
G AGTPBP1 ATP/GTP binding carboxypeptidase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:73,853,491...74,030,075
Ensembl chr 1:73,887,934...74,107,312 		JBrowse link
G AXIN1 axin 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3628833|PMID:16601693) MGI
Ensembl		 PMID:16601693 GO_REF:0000107 MGI:3628833 NCBI chr 6:40,155,797...40,218,330
Ensembl chr 6:40,158,244...40,218,343 		JBrowse link
G CCDC22 coiled-coil domain containing 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:42,329,320...42,343,270
Ensembl chr  X:42,328,755...42,343,270 		JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 NOT|involved_in ISO (PMID:16173922) UniProt PMID:16173922 NCBI chr 9:24,276,660...24,286,273
Ensembl chr 9:24,276,768...24,286,272 		JBrowse link
G CLU clusterin involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr25:29,982,811...29,999,565
Ensembl chr25:29,982,811...29,999,563 		JBrowse link
G DISC1 DISC1 scaffold protein acts_upstream_of_or_within ISO (MGI:4837265|PMID:20880836) MGI PMID:20880836 MGI:4837265 NCBI chr 4:7,524,336...7,825,143
Ensembl chr 4:7,524,397...7,822,558 		JBrowse link
G EGF epidermal growth factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:30,073,541...30,166,904
Ensembl chr32:30,073,950...30,166,295 		JBrowse link
G FBXO22 F-box protein 22 acts_upstream_of_or_within ISO (MGI:3840749|PMID:19319192) MGI PMID:19319192 MGI:3840749 NCBI chr30:40,100,768...40,127,708
Ensembl chr30:40,101,540...40,189,159 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:50,187,579...50,417,188
Ensembl chr15:50,189,240...50,417,195 		JBrowse link
G L3MBTL3 L3MBTL histone methyl-lysine binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:68,538,014...68,655,173
Ensembl chr 1:68,540,051...68,654,414 		JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in ISO (MGI:3803048|PMID:18619870)
(MGI:6478861|PMID:24638062)		 ARUK-UCL PMID:18619870 PMID:24638062 MGI:3803048 MGI:6478861 NCBI chr 2:70,188,382...70,215,361
Ensembl chr 2:70,152,739...70,333,073 		JBrowse link
G MAGEF1 MAGE family member F1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:17,543,381...17,545,089
Ensembl chr34:17,543,906...17,544,868 		JBrowse link
G PTEN phosphatase and tensin homolog involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:37,853,148...37,913,176
Ensembl chr26:37,835,661...37,913,176 		JBrowse link
G PTK2 protein tyrosine kinase 2 involved_in ISO (MGI:5306293|PMID:18206965) UniProt PMID:18206965 MGI:5306293 NCBI chr13:35,302,439...35,541,336
Ensembl chr13:35,303,380...35,541,294 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:30,137,546...30,264,221
Ensembl chr25:30,138,209...30,264,133 		JBrowse link
G RNF139 ring finger protein 139 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:22,560,180...22,572,986
Ensembl chr13:22,543,543...22,572,308 		JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:10,385,781...10,498,071
Ensembl chr 6:10,385,779...10,494,922 		JBrowse link
G SUMO3 small ubiquitin like modifier 3 acts_upstream_of_or_within ISO (MGI:3813414|PMID:18644859) MGI PMID:18644859 MGI:3813414 NCBI chr31:38,472,076...38,484,358 JBrowse link
G TRIM67 tripartite motif containing 67 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5427306|PMID:22337885) MGI
Ensembl		 PMID:22337885 GO_REF:0000107 MGI:5427306 NCBI chr 4:8,211,013...8,259,907
Ensembl chr 4:8,213,308...8,259,342 		JBrowse link
G TRMT12 tRNA methyltransferase 12 homolog involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:22,494,866...22,570,622
Ensembl chr13:22,543,543...22,572,308 		JBrowse link
G VCP valosin containing protein ISO RGD PMID:16103111 RGD:1599730 NCBI chr11:51,636,986...51,651,749
Ensembl chr11:51,637,411...51,651,714 		JBrowse link
regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:59,388,492...59,400,028
Ensembl chr 2:59,388,494...59,400,003 		JBrowse link
regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G USP19 ubiquitin specific peptidase 19 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:40,062,802...40,074,221
Ensembl chr20:40,064,599...40,074,082 		JBrowse link
regulation of proteasomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440 		JBrowse link
G BTRC beta-transducin repeat containing E3 ubiquitin protein ligase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3835892|PMID:19103752) MGI
Ensembl		 PMID:19103752 GO_REF:0000107 MGI:3835892 NCBI chr28:13,988,408...14,173,223
Ensembl chr28:13,988,432...14,169,581 		JBrowse link
G DLGAP1 DLG associated protein 1 involved_in ISO PMID:15496675 BHF-UCL PMID:15496675 RGD:8553458 NCBI chr 7:70,082,563...70,949,116
Ensembl chr 7:70,081,885...70,406,213 		JBrowse link
G DNAAF4 dynein axonemal assembly factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:20,778,497...20,871,304
Ensembl chr30:20,815,775...20,871,220 		JBrowse link
G EPM2A EPM2A glucan phosphatase, laforin acts_upstream_of_or_within ISO (MGI:5793002|PMID:27107699) MGI PMID:27107699 MGI:5793002 NCBI chr 1:36,835,775...36,977,653
Ensembl chr 1:36,870,594...36,931,847 		JBrowse link
G GPX1 glutathione peroxidase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:39,889,165...39,890,253
Ensembl chr20:39,889,174...39,890,260 		JBrowse link
G NFE2L1 NFE2 like bZIP transcription factor 1 acts_upstream_of_or_within ISO (MGI:6198859|PMID:29400713)
(MGI:5913760|PMID:27920251)		 MGI PMID:27920251 PMID:29400713 MGI:5913760 MGI:6198859 NCBI chr 9:24,344,697...24,356,918
Ensembl chr 9:24,346,585...24,362,646 		JBrowse link
G NUDT15 nudix hydrolase 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:3,416,702...3,424,607
Ensembl chr22:3,416,578...3,424,409 		JBrowse link
G PITHD1 PITH domain containing 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:6392185|PMID:31915251) MGI
Ensembl		 PMID:31915251 GO_REF:0000107 MGI:6392185 NCBI chr 2:75,714,592...75,721,301
Ensembl chr 2:75,708,988...75,721,286 		JBrowse link
G PKD1 polycystin 1, transient receptor potential channel interacting acts_upstream_of_or_within ISO (MGI:5461108|PMID:23001567)
(PMID:23001567)		 MGI PMID:23001567 MGI:5461108 NCBI chr 6:38,811,051...38,865,503
Ensembl chr 6:38,837,964...38,865,503 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:48,416,730...48,425,237
Ensembl chr20:48,409,045...48,426,669 		JBrowse link
G PSMD14 proteasome 26S subunit, non-ATPase 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:6,883,612...6,985,291
Ensembl chr36:6,889,622...6,984,974 		JBrowse link
G PSME3 proteasome activator subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:20,185,997...20,193,320
Ensembl chr 9:20,188,167...20,222,743 		JBrowse link
G RHBDF1 rhomboid 5 homolog 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:40,394,654...40,413,619
Ensembl chr 6:40,395,517...40,413,606 		JBrowse link
G TMF1 TATA element modulatory factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:22,684,150...22,716,107
Ensembl chr20:22,684,159...22,714,432 		JBrowse link
G UBB ubiquitin B acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:17571083) MGI
Ensembl		 PMID:17571083 GO_REF:0000107 NCBI chr 5:39,533,365...39,535,120
Ensembl chr 5:39,511,426...39,535,815 		JBrowse link
G UCHL5 ubiquitin C-terminal hydrolase L5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:6,004,595...6,045,999
Ensembl chr38:6,004,659...6,113,714 		JBrowse link
G USP14 ubiquitin specific peptidase 14 involved_in ISO (PMID:18162577) UniProt PMID:18162577 NCBI chr 7:67,035,774...67,080,082
Ensembl chr 7:67,035,843...67,079,465 		JBrowse link
regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARAF A-Raf proto-oncogene, serine/threonine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:41,180,082...41,191,579
Ensembl chr  X:41,180,250...41,191,310 		JBrowse link
G COMMD1 copper metabolism domain containing 1 involved_in ISS
IBA
IEA		 (PMID:21873635) UniProt
GO_Central
Ensembl		 PMID:21873635 GO_REF:0000024 GO_REF:0000107 NCBI chr10:61,886,281...62,059,610
Ensembl chr10:61,886,281...62,059,591 		JBrowse link
G DDA1 DET1 and DDB1 associated 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr20:45,440,046...45,448,564
Ensembl chr20:45,439,682...45,448,525 		JBrowse link
G DESI1 desumoylating isopeptidase 1 involved_in ISO (PMID:29666234) UniProt PMID:29666234 NCBI chr10:23,661,745...23,686,992
Ensembl chr10:23,661,745...23,681,331 		JBrowse link
G FOXF2 forkhead box F2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:1,841,165...1,846,649
Ensembl chr35:1,841,123...1,846,663 		JBrowse link
G GLMN glomulin, FKBP associated protein acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:22405651) MGI
Ensembl		 PMID:22405651 GO_REF:0000107 NCBI chr 6:56,631,186...56,678,397
Ensembl chr 6:56,644,456...56,678,399 		JBrowse link
G GNA12 G protein subunit alpha 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:14,375,144...14,476,018
Ensembl chr 6:14,413,576...14,473,764 		JBrowse link
G RAD23A RAD23 homolog A, nucleotide excision repair protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:49,244,330...49,250,058
Ensembl chr20:49,241,358...49,250,039 		JBrowse link
G RAD23B RAD23 homolog B, nucleotide excision repair protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:62,732,989...62,778,957
Ensembl chr11:62,732,984...62,775,978 		JBrowse link
G UBE2K ubiquitin conjugating enzyme E2 K acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3806928|PMID:18710920) MGI
Ensembl		 PMID:18710920 GO_REF:0000107 MGI:3806928 NCBI chr 3:72,713,035...72,780,199
Ensembl chr 3:72,717,236...72,780,210 		JBrowse link
G UBQLN4 ubiquilin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:41,764,209...41,778,457
Ensembl chr 7:41,764,253...41,777,002 		JBrowse link
G UFL1 UFM1 specific ligase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:20228063) MGI
Ensembl		 PMID:20228063 GO_REF:0000107 NCBI chr12:54,988,200...55,023,414
Ensembl chr12:54,988,264...55,021,626 		JBrowse link
G WNT10B Wnt family member 10B acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3820325|PMID:19056892) MGI
Ensembl		 PMID:19056892 GO_REF:0000107 MGI:3820325 NCBI chr27:5,599,905...5,605,506
Ensembl chr27:5,601,089...5,605,501 		JBrowse link
G XPO1 exportin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:61,541,647...61,588,397
Ensembl chr10:61,542,211...61,585,054 		JBrowse link
regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G L3MBTL3 L3MBTL histone methyl-lysine binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:68,538,014...68,655,173
Ensembl chr 1:68,540,051...68,654,414 		JBrowse link
G LATS1 large tumor suppressor kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:40,430,096...40,475,193
Ensembl chr 1:40,260,064...40,457,609 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:30,137,546...30,264,221
Ensembl chr25:30,138,209...30,264,133 		JBrowse link
G TMEM168 transmembrane protein 168 acts_upstream_of_or_within ISO (MGI:6511555|PMID:32175648) MGI PMID:32175648 MGI:6511555 NCBI chr14:52,312,109...52,340,151
Ensembl chr14:52,314,856...52,338,214 		JBrowse link
G UBE3A ubiquitin protein ligase E3A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:35,347,034...35,442,329
Ensembl chr 3:35,347,064...35,440,256 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16552
    metabolic process 10575
      primary metabolic process 7812
        protein metabolic process 5051
          regulation of protein metabolic process 2403
            regulation of proteolysis 648
              regulation of proteolysis involved in protein catabolic process 221
                negative regulation of proteolysis involved in protein catabolic process + 72
                positive regulation of proteolysis involved in protein catabolic process + 125
                regulation of proteasomal protein catabolic process + 181
                regulation of proteolysis associated with antigen processing and presentation + 0
                regulation of ubiquitin-dependent protein catabolic process + 159
Path 2
Term Annotations click to browse term
  biological_process 16552
    metabolic process 10575
      nitrogen compound metabolic process 7270
        organonitrogen compound metabolic process 5961
          protein metabolic process 5051
            proteolysis 1598
              regulation of proteolysis 648
                regulation of proteolysis involved in protein catabolic process 221
                  negative regulation of proteolysis involved in protein catabolic process + 72
                  positive regulation of proteolysis involved in protein catabolic process + 125
                  regulation of proteasomal protein catabolic process + 181
                  regulation of proteolysis associated with antigen processing and presentation + 0
                  regulation of ubiquitin-dependent protein catabolic process + 159
paths to the root