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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of proteolysis involved in protein catabolic process
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Accession:GO:1903050 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of proteolysis involved in cellular catabolic process.
Comment:overexpression of cathepsin C propeptide significantly increased the degradation of intestinal alkaline phosphatase (IAP)
Synonyms:exact_synonym: regulation of peptidolysis involved in cellular protein catabolic process;   regulation of peptidolysis involved in cellular protein catabolism;   regulation of proteolysis involved in cellular protein catabolic process
 related_synonym: regulation of peptidolysis during cellular protein catabolic process;   regulation of peptidolysis during cellular protein catabolism;   regulation of proteolysis during cellular protein catabolic process;   regulation of proteolysis during cellular protein catabolism


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negative regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:1,778,728...1,808,199
Ensembl chr19:2,736,565...2,763,440 		JBrowse link
G SVIP small VCP interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:22,828,321...22,837,536
Ensembl chr11:22,735,361...22,744,558 		JBrowse link
G USP14 ubiquitin specific peptidase 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:14,104,754...14,158,402
Ensembl chr18:17,745,733...17,797,070 		JBrowse link
negative regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP11 aquaporin 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:72,653,721...72,673,698
Ensembl chr11:76,295,778...76,315,292 		JBrowse link
G UBXN1 UBX domain protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:58,033,304...58,035,893
Ensembl chr11:61,386,797...61,389,404 		JBrowse link
G USP25 ubiquitin specific peptidase 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:2,468,993...2,618,200
Ensembl chr21:15,724,729...15,982,182 		JBrowse link
negative regulation of proteasomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALAD aminolevulinate dehydratase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:84,488,339...84,503,360
Ensembl chr 9:112,859,171...112,873,784 		JBrowse link
G F8A1 coagulation factor VIII associated 1 involved_in ISO (PMID:27815841) UniProt PMID:27815841 NCBI chr  X:144,366,123...144,367,842 JBrowse link
G GABARAPL2 GABA type A receptor associated protein like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:56,135,482...56,147,046
Ensembl chr16:75,483,459...75,495,019 		JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 involved_in ISO (MGI:6148636|PMID:17517623) ARUK-UCL PMID:17517623 MGI:6148636 RGD:13514081 NCBI chr 6:43,842,796...43,849,637
Ensembl chr 6:45,125,773...45,133,872 		JBrowse link
G LAMP3 lysosomal associated membrane protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:180,152,363...180,193,223
Ensembl chr 3:188,324,660...188,363,268 		JBrowse link
G LOC100985575 40-kDa huntingtin-associated protein involved_in ISO (PMID:27815841) UniProt PMID:27815841 NCBI chr  X:144,851,466...144,853,185 JBrowse link
G LOC100988585 transmembrane protein 220 acts_upstream_of_or_within ISO (MGI:5643882|PMID:25683716) MGI PMID:25683716 MGI:5643882 NCBI chr17:40,923,397...40,973,382
Ensembl chr17:45,703,642...45,720,520
Ensembl chr17:45,703,642...45,720,520 		JBrowse link
G MARCHF7 membrane associated ring-CH-type finger 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:47,004,211...47,059,901
Ensembl chr2B:164,377,605...164,432,907 		JBrowse link
G OPHN1 oligophrenin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:57,288,297...57,674,685
Ensembl chr  X:67,359,364...67,739,114 		JBrowse link
G PRKCG protein kinase C gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:50,823,372...50,849,003
Ensembl chr19:59,672,097...59,695,977 		JBrowse link
G PSME3IP1 proteasome activator subunit 3 interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:37,430,698...37,464,089
Ensembl chr16:56,563,353...56,596,619 		JBrowse link
G PSMF1 proteasome inhibitor subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:1,275,662...1,325,410
Ensembl chr20:1,043,513...1,092,237 		JBrowse link
G USP19 ubiquitin specific peptidase 19 involved_in ISO (MGI:5614537|PMID:25088257) ParkinsonsUK-UCL PMID:25088257 MGI:5614537 NCBI chr 3:49,032,373...49,045,238
Ensembl chr 3:50,100,216...50,125,112 		JBrowse link
negative regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG5 BAG cochaperone 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:84,182,879...84,189,180
Ensembl chr14:103,997,524...103,998,927 		JBrowse link
G BAG6 BAG cochaperone 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,300,126...31,313,829
Ensembl chr 6:32,190,037...32,204,321 		JBrowse link
G CAMLG calcium modulating ligand involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:130,138,644...130,144,540
Ensembl chr 5:136,282,910...136,295,382 		JBrowse link
G CCAR2 cell cycle and apoptosis regulator 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:21,854,803...21,870,556
Ensembl chr 8:18,794,027...18,808,571 		JBrowse link
G CLEC16A C-type lectin domain containing 16A acts_upstream_of_or_within ISO (MGI:5603233|PMID:24949970) MGI PMID:24949970 MGI:5603233 NCBI chr16:9,887,877...10,124,500
Ensembl chr16:11,109,869...11,343,512 		JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:3,276,292...3,290,433
Ensembl chr20:3,038,779...3,052,789 		JBrowse link
G EIF3H eukaryotic translation initiation factor 3 subunit H involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:113,320,059...113,440,769
Ensembl chr 8:115,863,490...115,973,872 		JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase involved_in ISO (PMID:15313915) UniProt PMID:15313915 NCBI chr 3:59,670,777...61,177,974 JBrowse link
G GIPC1 GIPC PDZ domain containing family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:14,041,192...14,059,402
Ensembl chr19:14,885,185...14,889,701 		JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 involved_in ISO (PMID:24613385) UniProt PMID:24613385 NCBI chr 6:43,842,796...43,849,637
Ensembl chr 6:45,125,773...45,133,872 		JBrowse link
G KLHL40 kelch like family member 40 acts_upstream_of_or_within ISO (MGI:5586592|PMID:24960163) MGI PMID:24960163 MGI:5586592 NCBI chr 3:42,592,977...42,600,100
Ensembl chr 3:43,657,128...43,664,055 		JBrowse link
G MAP1A microtubule associated protein 1A involved_in ISO (MGI:5703671|PMID:26609151) ARUK-UCL PMID:26609151 MGI:5703671 NCBI chr15:22,472,641...22,493,293
Ensembl chr15:40,627,099...40,647,752 		JBrowse link
G MTM1 myotubularin 1 acts_upstream_of_or_within ISO (MGI:5510937|PMID:23695157) MGI PMID:23695157 MGI:5510937 NCBI chr  X:140,218,742...140,323,495
Ensembl chr  X:150,174,758...150,255,381 		JBrowse link
G N4BP1 NEDD4 binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:28,809,881...28,881,352
Ensembl chr16:47,698,353...47,769,755 		JBrowse link
G NOP53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:22522597) UniProt PMID:22522597 NCBI chr19:44,739,739...44,751,303 JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:60,798,219...60,840,948
Ensembl chr  X:70,852,687...70,894,921 		JBrowse link
G PANO1 proapoptotic nucleolar protein 1 involved_in ISO (PMID:22094112) UniProt PMID:22094112 NCBI chr11:814,040...816,633 JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:6,722,260...6,745,915
Ensembl chr 1:7,969,280...7,993,271 		JBrowse link
G PBK PDZ binding kinase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5293269|PMID:21715333) MGI
Ensembl		 PMID:21715333 GO_REF:0000107 MGI:5293269 NCBI chr 8:27,084,789...27,112,986
Ensembl chr 8:24,285,395...24,313,658 		JBrowse link
G PHF20L1 PHD finger protein 20 like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:129,427,157...129,500,633
Ensembl chr 8:132,403,053...132,474,452 		JBrowse link
G RPL11 ribosomal protein L11 involved_in ISO (MGI:5897550|PMID:21804542) UniProt PMID:21804542 MGI:5897550 NCBI chr 1:22,883,157...22,887,806
Ensembl chr 1:23,868,688...23,873,313 		JBrowse link
G RYBP RING1 and YY1 binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:72,315,494...72,389,328
Ensembl chr 3:74,247,807...74,318,398 		JBrowse link
G SDCBP syndecan binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:54,992,627...55,022,560
Ensembl chr 8:56,643,962...56,673,833 		JBrowse link
G SENP1 SUMO specific peptidase 1 acts_upstream_of_or_within ISO (MGI:3818351|PMID:17981124) MGI PMID:17981124 MGI:3818351 NCBI chr12:40,624,200...40,689,837
Ensembl chr12:41,507,348...41,558,969 		JBrowse link
G SHH sonic hedgehog signaling molecule acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3624046|PMID:16611981) MGI
Ensembl		 PMID:16611981 GO_REF:0000107 MGI:3624046 NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651 		JBrowse link
G SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5310666|PMID:22285184) MGI
Ensembl		 PMID:22285184 GO_REF:0000107 MGI:5310666 NCBI chr 3:47,487,948...47,683,623
Ensembl chr 3:48,590,221...48,781,248 		JBrowse link
G TAF9 TATA-box binding protein associated factor 9 involved_in ISO (PMID:11278372) BHF-UCL PMID:11278372 NCBI chr 5:44,630,503...44,635,760 JBrowse link
G TLK2 tousled like kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:56,542,670...56,678,294
Ensembl chr17:61,689,998...61,830,394 		JBrowse link
G TRIM39 tripartite motif containing 39 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:30,104,381...30,121,649
Ensembl chr 6:30,975,260...30,995,764 		JBrowse link
G TTC36 tetratricopeptide repeat domain 36 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:6362140|PMID:31537781) MGI
Ensembl		 PMID:31537781 GO_REF:0000107 MGI:6362140 NCBI chr11:113,364,559...113,368,586
Ensembl chr11:117,295,191...117,298,928 		JBrowse link
G UBXN1 UBX domain protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:58,033,304...58,035,893
Ensembl chr11:61,386,797...61,389,404 		JBrowse link
G UCHL5 ubiquitin C-terminal hydrolase L5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:168,471,501...168,519,366
Ensembl chr 1:172,764,606...172,811,880 		JBrowse link
G USP7 ubiquitin specific peptidase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:7,825,332...7,895,095
Ensembl chr16:9,065,858...9,106,146 		JBrowse link
G USP9X ubiquitin specific peptidase 9 X-linked involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:33,535,543...33,683,220
Ensembl chr  X:41,232,041...41,379,910 		JBrowse link
G WAC WW domain containing adaptor with coiled-coil involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:28,685,294...28,777,176
Ensembl chr10:29,042,331...29,130,591 		JBrowse link
negative regulation of proteolysis involved in protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN2A cyclin dependent kinase inhibitor 2A involved_in
acts_upstream_of_or_within		 ISO (PMID:25217637)
(MGI:5468878|PMID:23277542)		 ParkinsonsUK-UCL
MGI		 PMID:23277542 PMID:25217637 MGI:5468878 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G EFNA1 ephrin A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:130,475,128...130,482,531
Ensembl chr 1:134,083,855...134,091,228 		JBrowse link
G EPHA4 EPH receptor A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:108,664,475...108,818,802
Ensembl chr2B:227,248,958...227,402,790 		JBrowse link
negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PABPN1L PABPN1 like, cytoplasmic acts_upstream_of_or_within ISO (MGI:6509513|PMID:32558204) MGI PMID:32558204 MGI:6509513 NCBI chr16:69,579,421...69,583,803
Ensembl chr16:89,234,156...89,237,595 		JBrowse link
G STYX serine/threonine/tyrosine interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:33,326,587...33,371,399
Ensembl chr14:51,610,523...51,651,096 		JBrowse link
negative regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A acts_upstream_of_or_within ISO (MGI:4461099|PMID:20100865) MGI PMID:20100865 MGI:4461099 NCBI chr 6:34,450,695...34,653,881
Ensembl chr 6:35,548,124...35,776,185 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A involved_in
acts_upstream_of_or_within		 ISO (PMID:16173922), (PMID:18560357)
(MGI:5468878|PMID:23277542)		 UniProt
MGI		 PMID:16173922 PMID:18560357 PMID:23277542 MGI:5468878 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 involved_in ISO (PMID:28031292) ARUK-UCL PMID:28031292 NCBI chr20:689,494...752,092
Ensembl chr20:456,629...521,126 		JBrowse link
G CSNK2A2 casein kinase 2 alpha 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:38,426,399...38,466,575
Ensembl chr16:57,557,270...57,596,218 		JBrowse link
G HFE homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:25,921,663...25,930,852
Ensembl chr 6:26,580,358...26,588,591 		JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 involved_in ISO (PMID:21628596) FlyBase PMID:21628596 NCBI chr 7:131,506,711...131,722,943 JBrowse link
G LOC100973105 40S ribosomal protein S7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:180,845,832...180,846,513 JBrowse link
G PDCL3 phosducin like 3 acts_upstream_of_or_within ISO (PMID:23792958) MGI PMID:23792958
G PML PML nuclear body scaffold involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:52,903,874...52,955,151
Ensembl chr15:71,658,884...71,710,883 		JBrowse link
G PRMT6 protein arginine methyltransferase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:109,582,715...109,586,744
Ensembl chr 1:108,699,098...108,700,225 		JBrowse link
G PSEN1 presenilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876 		JBrowse link
G PSEN2 presenilin 2 involved_in ISO (MGI:4887523|PMID:20208556) BHF-UCL PMID:20208556 MGI:4887523 NCBI chr 1:202,328,987...202,354,440
Ensembl chr 1:207,320,937...207,346,295 		JBrowse link
G QRICH2 glutamine rich 2 involved_in ISO (PMID:30683861)
(MGI:6277293|PMID:30683861)		 UniProt PMID:30683861 MGI:6277293 NCBI chr17:70,222,033...70,256,747
Ensembl chr17:75,774,651...75,807,651 		JBrowse link
G RPL11 ribosomal protein L11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:22,883,157...22,887,806
Ensembl chr 1:23,868,688...23,873,313 		JBrowse link
G RPL23 ribosomal protein L23 involved_in ISO (PMID:15314173) CAFA PMID:15314173 NCBI chr17:18,417,964...18,421,708
Ensembl chr17:18,690,682...18,698,253 		JBrowse link
G RPL5 ribosomal protein L5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:95,497,047...95,507,006
Ensembl chr 1:94,230,451...94,241,522 		JBrowse link
G RPS7 ribosomal protein S7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:3,593,350...3,599,106
Ensembl chr2A:3,512,079...3,517,785 		JBrowse link
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:1,778,728...1,808,199
Ensembl chr19:2,736,565...2,763,440 		JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4355593|PMID:19684112) MGI
Ensembl		 PMID:19684112 GO_REF:0000107 MGI:4355593 NCBI chr10:99,107,516...99,231,761
Ensembl chr10:102,571,886...102,696,472 		JBrowse link
G TAF1 TATA-box binding protein associated factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:60,630,137...60,729,904
Ensembl chr  X:70,684,217...70,782,323 		JBrowse link
G TRIM39 tripartite motif containing 39 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:30,104,381...30,121,649
Ensembl chr 6:30,975,260...30,995,764 		JBrowse link
G WNT1 Wnt family member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3628833|PMID:16601693) MGI
Ensembl		 PMID:16601693 GO_REF:0000107 MGI:3628833 NCBI chr12:39,767,839...39,772,460
Ensembl chr12:40,648,413...40,652,583 		JBrowse link
positive regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCAP31 B cell receptor associated protein 31 involved_in ISO (PMID:18555783) ParkinsonsUK-UCL PMID:18555783 NCBI chr  X:143,265,920...143,274,956 JBrowse link
G CAV1 caveolin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655 		JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:37,210,170...37,221,961
Ensembl chr16:56,343,025...56,355,164 		JBrowse link
G LOC100976022 B cell receptor associated protein 31 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr  X:153,137,992...153,161,628 JBrowse link
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:1,778,728...1,808,199
Ensembl chr19:2,736,565...2,763,440 		JBrowse link
G UBQLN1 ubiquilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:41,170,416...41,218,656
Ensembl chr 9:82,597,507...82,645,587 		JBrowse link
G UBQLN2 ubiquilin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:48,829,844...48,835,040
Ensembl chr  X:56,981,985...56,983,859 		JBrowse link
positive regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATXN3 ataxin 3 involved_in ISO (PMID:17000876) ParkinsonsUK-UCL PMID:17000876 NCBI chr14:72,693,446...72,741,772 JBrowse link
G BAG6 BAG cochaperone 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,300,126...31,313,829
Ensembl chr 6:32,190,037...32,204,321 		JBrowse link
G RNF185 ring finger protein 185 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:12,183,591...12,230,371
Ensembl chr22:30,020,353...30,066,266 		JBrowse link
G RNFT1 ring finger protein, transmembrane 1 involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr17:54,016,689...54,029,100
Ensembl chr17:58,858,416...58,869,908 		JBrowse link
G RNFT2 ring finger protein, transmembrane 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr12:114,315,117...114,430,273
Ensembl chr12:117,691,632...117,804,833 		JBrowse link
G TMEM259 transmembrane protein 259 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr19:983,507...994,212 JBrowse link
G TMEM67 transmembrane protein 67 ISO RGD PMID:19815549 RGD:8554391 NCBI chr 8:90,378,623...90,442,904
Ensembl chr 8:92,324,402...92,387,437 		JBrowse link
G USP13 ubiquitin specific peptidase 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:176,685,541...176,818,360
Ensembl chr 3:184,855,388...184,983,158 		JBrowse link
G WFS1 wolframin ER transmembrane glycoprotein involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 4:6,345,864...6,379,287 JBrowse link
positive regulation of proteasomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG2 BAG cochaperone 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:56,730,297...56,743,123
Ensembl chr 6:58,360,889...58,373,733 		JBrowse link
G DAB2IP DAB2 interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:92,696,798...92,912,425
Ensembl chr 9:121,143,457...121,254,336 		JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:3,276,292...3,290,433
Ensembl chr20:3,038,779...3,052,789 		JBrowse link
G ECSCR endothelial cell surface expressed chemotaxis and apoptosis regulator acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:19416853) MGI
Ensembl		 PMID:19416853 GO_REF:0000107 NCBI chr 5:134,819,568...134,833,508
Ensembl chr 5:140,940,578...140,955,140 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:144,660,676...144,874,404
Ensembl chr 4:156,312,274...156,402,351 		JBrowse link
G FMR1 fragile X messenger ribonucleoprotein 1 involved_in ISO (MGI:5770038|PMID:24709664) UniProt PMID:24709664 MGI:5770038 NCBI chr  X:136,937,889...136,976,828
Ensembl chr  X:147,365,748...147,405,321 		JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in ISO (PMID:22180649) BHF-UCL PMID:22180649
G LOC106634235 uncharacterized LOC106634235 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:20,548,631...20,739,999
Ensembl chr21:34,107,443...34,107,814
Ensembl chr21:34,107,443...34,107,814 		JBrowse link
G NUPR1 nuclear protein 1, transcriptional regulator involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:29,015,155...29,016,987 JBrowse link
G OSBPL7 oxysterol binding protein like 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:9,715,464...9,729,950
Ensembl chr17:9,897,768...9,912,065 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770 		JBrowse link
G PSMC1 proteasome 26S subunit, ATPase 1 involved_in IEA GOC GO_REF:0000108 NCBI chr14:70,873,846...70,889,988
Ensembl chr14:90,225,405...90,241,641 		JBrowse link
G PSMC2 proteasome 26S subunit, ATPase 2 involved_in IEA GOC GO_REF:0000108 NCBI chr 7:95,338,743...95,359,353
Ensembl chr 7:108,083,203...108,103,494 		JBrowse link
G PSMC3 proteasome 26S subunit, ATPase 3 involved_in IEA GOC GO_REF:0000108 NCBI chr11:47,366,986...47,374,677
Ensembl chr11:47,920,295...47,927,654 		JBrowse link
G PSMC4 proteasome 26S subunit, ATPase 4 involved_in IEA GOC GO_REF:0000108 NCBI chr19:37,018,112...37,028,490
Ensembl chr19:45,533,141...45,543,245 		JBrowse link
G PSMC5 proteasome 26S subunit, ATPase 5 involved_in IEA GOC GO_REF:0000108 NCBI chr17:57,906,934...57,911,551
Ensembl chr17:63,051,050...63,055,907 		JBrowse link
G PSMC6 proteasome 26S subunit, ATPase 6 involved_in IEA GOC GO_REF:0000108 NCBI chr14:33,303,689...33,324,502
Ensembl chr14:51,587,467...51,608,044 		JBrowse link
G RNF40 ring finger protein 40 ISO RGD PMID:12121982 RGD:633892 NCBI chr16:24,194,293...24,207,460
Ensembl chr16:31,129,352...31,142,280 		JBrowse link
G TMTC3 transmembrane O-mannosyltransferase targeting cadherins 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:85,683,455...85,741,118
Ensembl chr12:88,989,033...89,046,630 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:40,735,483...40,740,208
Ensembl chr 6:42,043,900...42,048,578 		JBrowse link
G XBP1 X-box binding protein 1 acts_upstream_of_or_within ISO (MGI:4946566|PMID:21317886) MGI PMID:21317886 MGI:4946566 NCBI chr22:9,863,479...9,869,491
Ensembl chr22:27,567,041...27,571,943 		JBrowse link
positive regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3589701|PMID:15937334) MGI
Ensembl		 PMID:15937334 GO_REF:0000107 MGI:3589701 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756 		JBrowse link
G ATG7 autophagy related 7 acts_upstream_of_or_within ISO (MGI:5465208|PMID:23152632) MGI PMID:23152632 MGI:5465208 NCBI chr 3:11,208,600...11,488,757
Ensembl chr 3:11,554,100...11,833,398 		JBrowse link
G AURKA aurora kinase A acts_upstream_of_or_within ISO (MGI:3697244|PMID:17060449) MGI PMID:17060449 MGI:3697244 NCBI chr20:52,707,757...52,730,579
Ensembl chr20:53,994,881...54,017,339 		JBrowse link
G AXIN1 axin 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3628833|PMID:16601693) MGI
Ensembl		 PMID:16601693 GO_REF:0000107 MGI:3628833 Ensembl chr16:278,239...337,891 JBrowse link
G BAG2 BAG cochaperone 2 NOT|involved_in ISO (MGI:6148635|PMID:19228967) ARUK-UCL PMID:19228967 MGI:6148635 NCBI chr 6:56,730,297...56,743,123
Ensembl chr 6:58,360,889...58,373,733 		JBrowse link
G BBS7 Bardet-Biedl syndrome 7 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:22302990) MGI
Ensembl		 PMID:22302990 GO_REF:0000107 NCBI chr 4:114,024,949...114,072,000
Ensembl chr 4:125,161,804...125,208,350 		JBrowse link
G CBFA2T3 CBFA2/RUNX1 partner transcriptional co-repressor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:69,592,293...69,662,321
Ensembl chr16:89,246,545...89,347,435 		JBrowse link
G CHFR checkpoint with forkhead and ring finger domains involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:5310666|PMID:22285184) Ensembl
MGI		 PMID:22285184 GO_REF:0000107 MGI:5310666 NCBI chr12:130,318,971...130,366,282
Ensembl chr12:134,923,458...134,968,832
Ensembl chr12:134,923,458...134,968,832 		JBrowse link
G CLU clusterin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:26,867,973...26,884,838
Ensembl chr 8:24,070,053...24,083,523 		JBrowse link
G COP1 COP1 E3 ubiquitin ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:151,459,354...151,727,131
Ensembl chr 1:155,156,185...155,425,156 		JBrowse link
G CSNK1A1 casein kinase 1 alpha 1 involved_in ISO (PMID:11955436)
(PMID:19364825)		 ParkinsonsUK-UCL
FlyBase		 PMID:11955436 PMID:19364825 NCBI chr 5:144,919,775...144,977,105
Ensembl chr 5:150,929,420...150,985,912 		JBrowse link
G CSNK1D casein kinase 1 delta involved_in ISO (MGI:3849793|PMID:19414593) UniProt PMID:19414593 MGI:3849793 NCBI chr17:76,648,677...76,683,054
Ensembl chr17:82,462,467...82,494,348 		JBrowse link
G CSNK1E casein kinase 1 epsilon involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:19,202,599...19,229,344
Ensembl chr22:37,027,094...37,072,942 		JBrowse link
G DAB2 DAB adaptor protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:70,951,198...71,004,836
Ensembl chr 5:76,022,143...76,041,443 		JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:3,276,292...3,290,433
Ensembl chr20:3,038,779...3,052,789 		JBrowse link
G DET1 DET1 partner of COP1 E3 ubiquitin ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:67,203,101...67,238,185
Ensembl chr15:86,411,937...86,444,789 		JBrowse link
G DNAJB2 DnaJ heat shock protein family (Hsp40) member B2 involved_in ISO (PMID:15936278) BHF-UCL PMID:15936278 NCBI chr2B:106,536,846...106,544,430
Ensembl chr2B:225,127,967...225,135,556 		JBrowse link
G DVL1 dishevelled segment polarity protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:92,469...106,748
Ensembl chr 1:1,292,052...1,301,008 		JBrowse link
G FBXO22 F-box protein 22 acts_upstream_of_or_within ISO (MGI:3840749|PMID:19319192) MGI PMID:19319192 MGI:3840749 NCBI chr15:54,817,076...54,849,271
Ensembl chr15:74,410,213...74,441,609 		JBrowse link
G GABARAP GABA type A receptor-associated protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:7,270,316...7,272,365
Ensembl chr17:7,257,659...7,260,276 		JBrowse link
G GBA1 glucosylceramidase beta 1 involved_in ISO (MGI:5501380|PMID:23707074) ParkinsonsUK-UCL PMID:23707074 MGI:5501380 NCBI chr 1:130,579,300...130,589,560
Ensembl chr 1:134,185,385...134,194,851 		JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3695876|PMID:17189825) MGI
Ensembl		 PMID:17189825 GO_REF:0000107 MGI:3695876 NCBI chr 6:53,052,145...53,102,794
Ensembl chr 6:54,687,315...54,734,994 		JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:39,118,330...39,130,768
Ensembl chr19:47,710,197...47,726,948 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5437589|PMID:22660580) MGI
Ensembl		 PMID:22660580 GO_REF:0000107 MGI:5437589 NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771 		JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:24613385) UniProt PMID:24613385 NCBI chr 6:31,476,710...31,491,411 JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:24613385) UniProt PMID:24613385 NCBI chr 6:31,488,882...31,491,412 JBrowse link
G HSPBP1 HSPA (Hsp70) binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:52,303,121...52,322,771
Ensembl chr19:60,995,202...61,013,756 		JBrowse link
G IL33 interleukin 33 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5437589|PMID:22660580) MGI
Ensembl		 PMID:22660580 GO_REF:0000107 MGI:5437589 NCBI chr 9:6,027,014...6,069,540
Ensembl chr 9:6,234,178...6,248,624 		JBrowse link
G KLHL40 kelch like family member 40 involved_in ISO (MGI:5700633|PMID:25940086) UniProt PMID:25940086 MGI:5700633 NCBI chr 3:42,592,977...42,600,100
Ensembl chr 3:43,657,128...43,664,055 		JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:48,343,621...48,488,337
Ensembl chr12:49,205,930...49,350,462 		JBrowse link
G MDM2 MDM2 proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:66,322,340...66,357,010
Ensembl chr12:69,102,084...69,133,278 		JBrowse link
G NKD2 NKD inhibitor of WNT signaling pathway 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:1,285,217...1,311,285
Ensembl chr 5:1,075,172...1,081,664 		JBrowse link
G NOP53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:25818168), (PMID:27323397)
(MGI:5897550|PMID:21804542)		 UniProt PMID:21804542 PMID:25818168 PMID:27323397 MGI:5897550 NCBI chr19:44,739,739...44,751,303 JBrowse link
G NUB1 negative regulator of ubiquitin like proteins 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:142,927,730...142,964,475
Ensembl chr 7:155,079,243...155,114,676 		JBrowse link
G PABIR1 PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:56,007,323...56,011,655
Ensembl chr 9:67,544,489...67,545,352 		JBrowse link
G PIAS1 protein inhibitor of activated STAT 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:47,006,718...47,141,035
Ensembl chr15:65,276,530...65,410,105 		JBrowse link
G PLK1 polo like kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:14,420,972...14,432,821
Ensembl chr16:23,928,773...23,940,779 		JBrowse link
G PLK2 polo like kinase 2 ISO RGD PMID:18723513 RGD:7241135 NCBI chr 5:55,543,828...55,550,116
Ensembl chr 5:57,177,836...57,184,793 		JBrowse link
G PRICKLE1 prickle planar cell polarity protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:46,127,673...46,262,333
Ensembl chr12:47,100,393...47,126,102 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770 		JBrowse link
G PSEN1 presenilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876 		JBrowse link
G PSEN2 presenilin 2 involved_in ISO (MGI:4887523|PMID:20208556) BHF-UCL PMID:20208556 MGI:4887523 NCBI chr 1:202,328,987...202,354,440
Ensembl chr 1:207,320,937...207,346,295 		JBrowse link
G PSMD10 proteasome 26S subunit, non-ATPase 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:97,182,090...97,189,523
Ensembl chr  X:107,552,186...107,559,616 		JBrowse link
G RACK1 receptor for activated C kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:176,462,991...176,470,153
Ensembl chr 5:183,712,665...183,720,128 		JBrowse link
G RAD23A RAD23 homolog A, nucleotide excision repair protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:12,508,232...12,516,068
Ensembl chr19:13,250,718...13,258,482 		JBrowse link
G RBX1 ring-box 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:21,845,351...21,866,627
Ensembl chr22:39,941,405...39,962,175 		JBrowse link
G RCHY1 ring finger and CHY zinc finger domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:48,691,213...48,725,979
Ensembl chr 4:54,526,202...54,561,048 		JBrowse link
G RFPL1 ret finger protein like 1 involved_in ISO (PMID:20725088) UniProt PMID:20725088 NCBI chr22:10,485,218...10,488,052 JBrowse link
G RNF180 ring finger protein 180 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3819024|PMID:18363970), (MGI:5505713|PMID:23926250) MGI
Ensembl		 PMID:18363970 PMID:23926250 GO_REF:0000107 MGI:3819024 MGI:5505713 NCBI chr 5:49,624,452...49,841,741
Ensembl chr 5:51,280,064...51,454,750 		JBrowse link
G SH3RF2 SH3 domain containing ring finger 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:141,386,060...141,530,993
Ensembl chr 5:147,401,188...147,545,703 		JBrowse link
G SIRT2 sirtuin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:35,984,453...36,005,582
Ensembl chr19:44,533,965...44,554,799 		JBrowse link
G SMAD7 SMAD family member 7 involved_in ISO (PMID:11278251) BHF-UCL PMID:11278251 NCBI chr18:42,306,324...42,337,214 JBrowse link
G SOCS4 suppressor of cytokine signaling 4 involved_in IEA InterPro GO_REF:0000002 NCBI chr14:35,614,238...35,636,531
Ensembl chr14:53,904,783...53,906,105 		JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr2A:46,813,589...46,878,102
Ensembl chr2A:47,804,431...47,806,041 		JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:694,414...696,682 JBrowse link
G SUMO1 small ubiquitin like modifier 1 involved_in ISO (PMID:18408734) UniProt PMID:18408734 NCBI chr2B:89,461,773...89,493,879
Ensembl chr2B:207,613,654...207,645,590 		JBrowse link
G SUMO2 small ubiquitin like modifier 2 involved_in ISO (PMID:18408734) UniProt PMID:18408734 NCBI chr17:69,115,433...69,130,065 JBrowse link
G TAF1 TATA-box binding protein associated factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:60,630,137...60,729,904
Ensembl chr  X:70,684,217...70,782,323 		JBrowse link
G TRIB1 tribbles pseudokinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:122,115,194...122,123,319
Ensembl chr 8:124,867,359...124,872,924 		JBrowse link
G TRIB2 tribbles pseudokinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:12,705,043...12,730,932
Ensembl chr2A:12,847,631...12,873,499 		JBrowse link
G UBE2V2 ubiquitin conjugating enzyme E2 V2 ISO RGD PMID:12750002 RGD:1299567 NCBI chr 8:44,435,496...44,488,517
Ensembl chr 8:41,856,429...41,878,320 		JBrowse link
G USP5 ubiquitin specific peptidase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:6,983,941...6,998,469
Ensembl chr12:6,895,416...6,909,936 		JBrowse link
G VCP valosin containing protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:34,907,147...34,923,227
Ensembl chr 9:35,712,937...35,729,588 		JBrowse link
G ZER1 zyg-11 related cell cycle regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:99,853,433...99,895,399
Ensembl chr 9:128,519,972...128,560,098 		JBrowse link
G ZFAND2A zinc finger AN1-type containing 2A acts_upstream_of_or_within ISO (MGI:3663213|PMID:16973439) MGI PMID:16973439 MGI:3663213 NCBI chr 7:1,392,979...1,401,283
Ensembl chr 7:1,518,912...1,526,107 		JBrowse link
G ZYG11B zyg-11 family member B, cell cycle regulator involved_in ISO (PMID:31273098) UniProt PMID:31273098 NCBI chr 1:51,987,678...52,087,093 JBrowse link
positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLK3 polo like kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:44,104,564...44,110,162
Ensembl chr 1:45,470,016...45,476,021 		JBrowse link
G SIRT2 sirtuin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:35,984,453...36,005,582
Ensembl chr19:44,533,965...44,554,799 		JBrowse link
positive regulation of proteolysis involved in protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP5IF1 ATP synthase inhibitory factor subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:27,495,250...27,497,255
Ensembl chr 1:28,532,091...28,542,607 		JBrowse link
G CTSC cathepsin C involved_in ISO PMID:18307834 ParkinsonsUK-UCL PMID:18307834 RGD:8661625 NCBI chr11:83,299,827...83,345,383
Ensembl chr11:86,890,010...86,933,847 		JBrowse link
G GBA1 glucosylceramidase beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:130,579,300...130,589,560
Ensembl chr 1:134,185,385...134,194,851 		JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in ISO (MGI:5444793|PMID:22949502) ARUK-UCL PMID:22949502 MGI:5444793 NCBI chr 1:30,005,941...30,031,366
Ensembl chr 1:31,032,963...31,058,385 		JBrowse link
G RGN regucalcin ISO RGD PMID:1513338 RGD:9590188 NCBI chr  X:39,513,135...39,530,188
Ensembl chr  X:47,371,226...47,388,881 		JBrowse link
positive regulation of transcription factor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBXW8 F-box and WD repeat domain containing 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:114,487,476...114,607,384
Ensembl chr12:117,863,254...117,983,269 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 involved_in ISO (MGI:6148490|PMID:29153991) UniProt PMID:29153991 MGI:6148490 NCBI chr10:45,806,748...45,936,362 JBrowse link
G MAPK9 mitogen-activated protein kinase 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:175,437,167...175,495,469
Ensembl chr 5:182,748,381...182,795,135 		JBrowse link
G SIRT6 sirtuin 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:3,196,092...3,204,602
Ensembl chr19:4,146,057...4,154,126 		JBrowse link
positive regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AXIN1 axin 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3628833|PMID:16601693) MGI
Ensembl		 PMID:16601693 GO_REF:0000107 MGI:3628833 Ensembl chr16:278,239...337,891 JBrowse link
G CCDC22 coiled-coil domain containing 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:41,535,439...41,550,547
Ensembl chr  X:49,387,980...49,402,742 		JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 NOT|involved_in ISO (PMID:16173922) UniProt PMID:16173922 NCBI chr17:9,556,313...9,567,099
Ensembl chr17:9,738,141...9,749,302 		JBrowse link
G CLU clusterin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:26,867,973...26,884,838
Ensembl chr 8:24,070,053...24,083,523 		JBrowse link
G DISC1 DISC1 scaffold protein acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4837265|PMID:20880836) MGI
Ensembl		 PMID:20880836 GO_REF:0000107 MGI:4837265 NCBI chr 1:207,180,513...207,594,684
Ensembl chr 1:212,265,520...212,612,079 		JBrowse link
G EGF epidermal growth factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:102,410,724...102,509,691
Ensembl chr 4:112,977,565...113,076,460 		JBrowse link
G FBXO22 F-box protein 22 acts_upstream_of_or_within ISO (MGI:3840749|PMID:19319192) MGI PMID:19319192 MGI:3840749 NCBI chr15:54,817,076...54,849,271
Ensembl chr15:74,410,213...74,441,609 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:144,660,676...144,874,404
Ensembl chr 4:156,312,274...156,402,351 		JBrowse link
G L3MBTL3 L3MBTL histone methyl-lysine binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:127,814,847...127,938,220
Ensembl chr 6:131,922,967...132,045,708 		JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in ISO (MGI:3803048|PMID:18619870)
(MGI:6478861|PMID:24638062)		 ARUK-UCL PMID:18619870 PMID:24638062 MGI:3803048 MGI:6478861 NCBI chr 1:30,005,941...30,031,366
Ensembl chr 1:31,032,963...31,058,385 		JBrowse link
G LOC100967527 AGBL carboxypeptidase 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:6149282|PMID:29593216) MGI
Ensembl		 PMID:29593216 GO_REF:0000107 MGI:6149282 NCBI chr 1:47,807,888...49,264,213
Ensembl chr 1:49,511,379...49,560,314
Ensembl chr 1:49,511,379...49,560,314 		JBrowse link
G LOC100970998 small ubiquitin like modifier 3 acts_upstream_of_or_within ISO (MGI:3813414|PMID:18644859) MGI PMID:18644859 MGI:3813414 NCBI chr 1:224,215,377...224,217,052 JBrowse link
G MAGEF1 MAGE family member F1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:181,750,186...181,751,900
Ensembl chr 3:190,229,865...190,230,791 		JBrowse link
G PTEN phosphatase and tensin homolog involved_in ISO (PMID:21241890) BHF-UCL PMID:21241890 NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605 		JBrowse link
G PTK2 protein tyrosine kinase 2 involved_in ISO (MGI:5306293|PMID:18206965) UniProt PMID:18206965 MGI:5306293 NCBI chr 8:137,330,777...137,677,306
Ensembl chr 8:140,412,773...140,684,898 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474 		JBrowse link
G PYHIN1 pyrin and HIN domain family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:134,283,998...134,329,531
Ensembl chr 1:138,081,611...138,127,115 		JBrowse link
G RNF139 ring finger protein 139 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:121,158,715...121,172,069
Ensembl chr 8:123,912,589...123,924,720 		JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:90,995,923...91,112,240
Ensembl chr 7:104,500,965...104,568,046 		JBrowse link
G TRIM67 tripartite motif containing 67 acts_upstream_of_or_within ISO (MGI:5427306|PMID:22337885) MGI PMID:22337885 MGI:5427306 NCBI chr 1:206,710,490...206,770,111 JBrowse link
G VCP valosin containing protein ISO RGD PMID:16103111 RGD:1599730 NCBI chr 9:34,907,147...34,923,227
Ensembl chr 9:35,712,937...35,729,588 		JBrowse link
regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:37,210,170...37,221,961
Ensembl chr16:56,343,025...56,355,164 		JBrowse link
regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G QARS1 glutaminyl-tRNA synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:49,020,310...49,029,443
Ensembl chr 3:50,100,216...50,125,112 		JBrowse link
G USP19 ubiquitin specific peptidase 19 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:49,032,373...49,045,238
Ensembl chr 3:50,100,216...50,125,112 		JBrowse link
regulation of proteasomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490 		JBrowse link
G BTRC beta-transducin repeat containing E3 ubiquitin protein ligase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3835892|PMID:19103752) MGI
Ensembl		 PMID:19103752 GO_REF:0000107 MGI:3835892 NCBI chr10:97,958,527...98,159,550
Ensembl chr10:101,431,318...101,632,496 		JBrowse link
G DLGAP1 DLG associated protein 1 involved_in ISO PMID:15496675 BHF-UCL PMID:15496675 RGD:8553458 NCBI chr18:9,816,171...10,781,490
Ensembl chr18:12,704,306...13,091,118 		JBrowse link
G DNAAF4 dynein axonemal assembly factor 4 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr15:34,382,064...34,469,432
Ensembl chr15:52,711,349...52,791,281 		JBrowse link
G EPM2A EPM2A glucan phosphatase, laforin acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5793002|PMID:27107699) MGI
Ensembl		 PMID:27107699 GO_REF:0000107 MGI:5793002 NCBI chr 6:143,179,097...143,525,223 JBrowse link
G GPX1 glutathione peroxidase 1 involved_in ISO (PMID:12751788) BHF-UCL PMID:12751788 NCBI chr 3:49,280,038...49,281,455
Ensembl chr 3:50,360,947...50,361,826 		JBrowse link
G LOC100972297 nuclear pore complex-interacting protein family member B15 acts_upstream_of_or_within ISO (MGI:5461108|PMID:23001567) MGI PMID:23001567 MGI:5461108 NCBI chr16:604,927...1,697,831 JBrowse link
G NFE2L1 NFE2 like bZIP transcription factor 1 acts_upstream_of_or_within ISO (MGI:6198859|PMID:29400713)
(MGI:5913760|PMID:27920251)		 MGI PMID:27920251 PMID:29400713 MGI:5913760 MGI:6198859 NCBI chr17:9,476,482...9,489,661
Ensembl chr17:9,657,847...9,671,040 		JBrowse link
G NUDT15 nudix hydrolase 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:29,189,459...29,198,825
Ensembl chr13:47,891,557...47,900,971 		JBrowse link
G PITHD1 PITH domain containing 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:6392185|PMID:31915251) MGI
Ensembl		 PMID:31915251 GO_REF:0000107 MGI:6392185 NCBI chr 1:22,970,081...22,979,841
Ensembl chr 1:23,954,980...23,964,085 		JBrowse link
G PKD1 polycystin 1, transient receptor potential channel interacting acts_upstream_of_or_within ISO (PMID:23001567) MGI PMID:23001567 NCBI chr16:604,366...605,560 JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:13,657,344...13,683,864
Ensembl chr19:14,385,191...14,406,205 		JBrowse link
G PSMD14 proteasome 26S subunit, non-ATPase 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:48,602,395...48,705,229
Ensembl chr2B:165,972,229...166,074,879 		JBrowse link
G PSME3 proteasome activator subunit 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:14,474,604...14,484,522
Ensembl chr17:14,700,660...14,711,735 		JBrowse link
G RHBDF1 rhomboid 5 homolog 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:49,031...57,222 JBrowse link
G TMF1 TATA element modulatory factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:68,955,866...68,988,353
Ensembl chr 3:70,322,814...70,355,460 		JBrowse link
G UBB ubiquitin B acts_upstream_of_or_within ISO (PMID:17571083) MGI PMID:17571083 NCBI chr17:35,286,699...35,288,429 JBrowse link
G UCHL5 ubiquitin C-terminal hydrolase L5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:168,471,501...168,519,366
Ensembl chr 1:172,764,606...172,811,880 		JBrowse link
G USP14 ubiquitin specific peptidase 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:14,104,754...14,158,402
Ensembl chr18:17,745,733...17,797,070 		JBrowse link
regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARAF A-Raf proto-oncogene, serine/threonine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:39,997,026...40,007,783
Ensembl chr  X:47,893,153...47,904,643 		JBrowse link
G COMMD1 copper metabolism domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:61,970,830...62,216,677
Ensembl chr2A:63,121,521...63,349,131 		JBrowse link
G DDA1 DET1 and DDB1 associated 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr19:16,797,750...16,808,427
Ensembl chr19:17,771,925...17,785,267 		JBrowse link
G DESI1 desumoylating isopeptidase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:22,493,114...22,516,191
Ensembl chr22:40,578,968...40,602,094 		JBrowse link
G FOXF2 forkhead box F2 involved_in ISO (PMID:29374064) UniProt PMID:29374064 NCBI chr 6:1,209,899...1,215,970 JBrowse link
G GLMN glomulin, FKBP associated protein acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:22405651) MGI
Ensembl		 PMID:22405651 GO_REF:0000107 NCBI chr 1:94,907,342...94,963,052
Ensembl chr 1:93,646,499...93,701,430 		JBrowse link
G GNA12 G protein subunit alpha 12 involved_in ISO (PMID:22609986)
(MGI:5448916|PMID:22609986)		 UniProt PMID:22609986 MGI:5448916 NCBI chr 7:2,989,832...3,104,848 JBrowse link
G RAD23A RAD23 homolog A, nucleotide excision repair protein involved_in IEA Ensembl
UniProt		 GO_REF:0000107 GO_REF:0000117 NCBI chr19:12,508,232...12,516,068
Ensembl chr19:13,250,718...13,258,482 		JBrowse link
G RAD23B RAD23 homolog B, nucleotide excision repair protein involved_in IEA Ensembl
UniProt		 GO_REF:0000107 GO_REF:0000117 NCBI chr 9:78,433,461...78,482,157
Ensembl chr 9:106,622,377...106,670,317 		JBrowse link
G UBE2K ubiquitin conjugating enzyme E2 K acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3806928|PMID:18710920) MGI
Ensembl		 PMID:18710920 GO_REF:0000107 MGI:3806928 NCBI chr 4:34,026,942...34,111,923
Ensembl chr 4:39,877,966...39,960,397 		JBrowse link
G UBQLN1 ubiquilin 1 involved_in IEA UniProt GO_REF:0000117 NCBI chr 9:41,170,416...41,218,656
Ensembl chr 9:82,597,507...82,645,587 		JBrowse link
G UBQLN2 ubiquilin 2 involved_in IEA UniProt GO_REF:0000117 NCBI chr  X:48,829,844...48,835,040
Ensembl chr  X:56,981,985...56,983,859 		JBrowse link
G UBQLN3 ubiquilin 3 involved_in IEA UniProt GO_REF:0000117 NCBI chr11:5,651,750...5,654,422
Ensembl chr11:5,334,275...5,336,242 		JBrowse link
G UBQLN4 ubiquilin 4 involved_in IEA Ensembl
UniProt		 GO_REF:0000107 GO_REF:0000117 NCBI chr 1:131,374,635...131,395,986
Ensembl chr 1:135,209,490...135,225,666 		JBrowse link
G UFL1 UFM1 specific ligase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:20228063) MGI
Ensembl		 PMID:20228063 GO_REF:0000107 NCBI chr 6:94,356,440...94,389,920
Ensembl chr 6:98,242,756...98,274,377 		JBrowse link
G WNT10B Wnt family member 10B acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3820325|PMID:19056892) MGI
Ensembl		 PMID:19056892 GO_REF:0000107 MGI:3820325 NCBI chr12:39,771,163...39,785,411
Ensembl chr12:40,659,106...40,665,734 		JBrowse link
G XPO1 exportin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:61,562,372...61,622,841
Ensembl chr2A:62,698,935...62,757,793 		JBrowse link
regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G L3MBTL3 L3MBTL histone methyl-lysine binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:127,814,847...127,938,220
Ensembl chr 6:131,922,967...132,045,708 		JBrowse link
G LATS1 large tumor suppressor kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:147,476,913...147,533,491
Ensembl chr 6:152,182,394...152,239,276 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474 		JBrowse link
G TMEM168 transmembrane protein 168 acts_upstream_of_or_within ISO (MGI:6511555|PMID:32175648) MGI PMID:32175648 MGI:6511555 NCBI chr 7:104,729,362...104,756,299
Ensembl chr 7:117,433,384...117,458,000 		JBrowse link
G UBE3A ubiquitin protein ligase E3A involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:4,494,029...4,595,415
Ensembl chr15:22,747,075...22,825,459 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15412
    metabolic process 10019
      primary metabolic process 7256
        protein metabolic process 4625
          regulation of protein metabolic process 2229
            regulation of proteolysis 634
              regulation of proteolysis involved in protein catabolic process 226
                negative regulation of proteolysis involved in protein catabolic process + 75
                positive regulation of proteolysis involved in protein catabolic process + 124
                regulation of proteasomal protein catabolic process + 186
                regulation of proteolysis associated with antigen processing and presentation + 0
                regulation of ubiquitin-dependent protein catabolic process + 164
Path 2
Term Annotations click to browse term
  biological_process 15412
    metabolic process 10019
      nitrogen compound metabolic process 6717
        organonitrogen compound metabolic process 5498
          protein metabolic process 4625
            proteolysis 1505
              regulation of proteolysis 634
                regulation of proteolysis involved in protein catabolic process 226
                  negative regulation of proteolysis involved in protein catabolic process + 75
                  positive regulation of proteolysis involved in protein catabolic process + 124
                  regulation of proteasomal protein catabolic process + 186
                  regulation of proteolysis associated with antigen processing and presentation + 0
                  regulation of ubiquitin-dependent protein catabolic process + 164
paths to the root