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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of glycoprotein metabolic process
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Accession:GO:1903019 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process.
Comment:human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein
Synonyms:exact_synonym: down regulation of glycoprotein metabolic process;   down regulation of glycoprotein metabolism;   downregulation of glycoprotein metabolic process;   downregulation of glycoprotein metabolism;   negative regulation of glycoprotein metabolism
 narrow_synonym: inhibition of glycoprotein metabolic process;   inhibition of glycoprotein metabolism



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negative regulation of glycoprotein metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apcs amyloid P component, serum involved_in ISO GO_Central GO_REF:0000119 NCBI chr 1:172,721,528...172,722,516
Ensembl chr 1:172,721,528...172,722,608
JBrowse link
G Ptx3 pentraxin related gene involved_in ISO GO_Central GO_REF:0000119 NCBI chr 3:66,127,308...66,133,227
Ensembl chr 3:66,127,331...66,133,226
JBrowse link
negative regulation by host of viral glycoprotein metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apcs amyloid P component, serum involved_in ISO
IEA
GO_Central
Ensembl
GO_REF:0000107 GO_REF:0000119 NCBI chr 1:172,721,528...172,722,516
Ensembl chr 1:172,721,528...172,722,608
JBrowse link
G Ptx3 pentraxin related gene involved_in IEA
ISO
Ensembl
GO_Central
GO_REF:0000107 GO_REF:0000119 NCBI chr 3:66,127,308...66,133,227
Ensembl chr 3:66,127,331...66,133,226
JBrowse link
negative regulation of amyloid precursor protein biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aatf apoptosis antagonizing transcription factor acts_upstream_of_or_within IDA (PMID:14627703) MGI PMID:14627703 NCBI chr11:84,313,682...84,404,433
Ensembl chr11:84,313,681...84,404,348
JBrowse link
G Abca7 ATP-binding cassette, sub-family A member 7 involved_in IDA (PMID:18429932) Alzheimers_University_of_Toronto PMID:18429932 NCBI chr10:79,832,328...79,851,406
Ensembl chr10:79,832,328...79,851,406
JBrowse link
G Ago2 argonaute RISC catalytic subunit 2 involved_in ISO GO_Central GO_REF:0000096 NCBI chr15:72,967,693...73,056,777
Ensembl chr15:72,967,693...73,056,784
JBrowse link
G Bace2 beta-site APP-cleaving enzyme 2 involved_in ISS
ISO
UniProt
GO_Central
GO_REF:0000024 GO_REF:0000119 NCBI chr16:97,157,928...97,244,136
Ensembl chr16:97,157,942...97,244,136
JBrowse link
G Itm2a integral membrane protein 2A involved_in IBA GO_Central GO_REF:0000033 NCBI chr  X:106,440,801...106,446,966
Ensembl chr  X:106,440,705...106,446,982
JBrowse link
G Itm2b integral membrane protein 2B involved_in IBA
ISS
ISO
GO_Central
UniProt
GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr14:73,599,666...73,622,729
Ensembl chr14:73,599,666...73,622,729
JBrowse link
G Itm2c integral membrane protein 2C involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:85,822,231...85,836,419
Ensembl chr 1:85,822,002...85,836,396
JBrowse link
G Mir106a microRNA 106a involved_in ISO (PMID:18684319) ARUK-UCL PMID:18684319 NCBI chr  X:51,831,380...51,831,444
Ensembl chr  X:51,831,380...51,831,444
JBrowse link
G Mir144 microRNA 144 involved_in ISO (PMID:27329039) ARUK-UCL PMID:27329039 NCBI chr11:77,963,831...77,963,896
Ensembl chr11:77,963,831...77,963,896
JBrowse link
G Mir153 microRNA 153 involved_in ISO (PMID:21982160) ARUK-UCL PMID:21982160 NCBI chr12:117,214,437...117,214,505
Ensembl chr12:117,214,437...117,214,505
JBrowse link
G Mir17 microRNA 17 involved_in ISO (PMID:21982160) ARUK-UCL PMID:21982160 NCBI chr14:115,281,103...115,281,186
Ensembl chr14:115,281,103...115,281,186
JBrowse link
G Mir20a microRNA 20a involved_in ISO (PMID:21982160) ARUK-UCL PMID:21982160 NCBI chr14:115,281,589...115,281,695
Ensembl chr14:115,281,589...115,281,695
JBrowse link
G Mir298 microRNA 298 involved_in ISO (PMID:31942037) ARUK-UCL PMID:31942037 NCBI chr 2:174,109,297...174,109,378
Ensembl chr 2:174,109,297...174,109,378
JBrowse link
G Mir31 microRNA 31 involved_in ISO (PMID:32069773) ARUK-UCL PMID:32069773 NCBI chr 4:88,828,794...88,828,899
Ensembl chr 4:88,828,794...88,828,899
JBrowse link
G Mir323 microRNA 323 involved_in ISO (PMID:21982160) ARUK-UCL PMID:21982160 NCBI chr12:109,678,942...109,679,027
Ensembl chr12:109,678,942...109,679,027
JBrowse link
G Mir455 microRNA 455 involved_in ISO (PMID:31181293) ARUK-UCL PMID:31181293 NCBI chr 4:63,175,088...63,175,169
Ensembl chr 4:63,175,088...63,175,169
JBrowse link
negative regulation of elastin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst3 cystatin C involved_in ISO GO_Central GO_REF:0000119 NCBI chr 2:148,713,642...148,717,432
Ensembl chr 2:148,713,642...148,717,612
JBrowse link
negative regulation of glycoprotein biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot8 acyl-CoA thioesterase 8 involved_in ISS
ISO
UniProt
GO_Central
GO_REF:0000024 GO_REF:0000119 NCBI chr 2:164,634,688...164,662,132
Ensembl chr 2:164,634,685...164,646,802
JBrowse link
G Hbegf heparin-binding EGF-like growth factor involved_in IEA
ISO
Ensembl
GO_Central
GO_REF:0000096 GO_REF:0000107 NCBI chr18:36,637,980...36,648,858
Ensembl chr18:36,637,980...36,648,858
JBrowse link
G Jak3 Janus kinase 3 involved_in IMP (PMID:9498750) BHF-UCL PMID:9498750 NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219
JBrowse link
G Mir144 microRNA 144 acts_upstream_of ISO (PMID:27785072) DIBU PMID:27785072 NCBI chr11:77,963,831...77,963,896
Ensembl chr11:77,963,831...77,963,896
JBrowse link
negative regulation of protein glycosylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mgat4d MGAT4 family, member C involved_in IDA (PMID:20805325) UniProt PMID:20805325 NCBI chr 8:84,075,101...84,106,031
Ensembl chr 8:84,075,100...84,108,949
JBrowse link
G Oga O-GlcNAcase involved_in ISO RGD
GO_Central
PMID:16332679 GO_REF:0000096 RGD:2305959 NCBI chr19:45,738,698...45,772,274
Ensembl chr19:45,738,698...45,772,276
JBrowse link
negative regulation of proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc2a10 solute carrier family 2 (facilitated glucose transporter), member 10 involved_in
acts_upstream_of_or_within
IEA
ISO
Ensembl
GO_Central
GO_REF:0000107 GO_REF:0000119 NCBI chr 2:165,345,817...165,361,837
Ensembl chr 2:165,345,707...165,361,837
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28626
    cellular process 18393
      metabolic process 11623
        carbohydrate derivative metabolic process 1054
          glycoprotein metabolic process 401
            negative regulation of glycoprotein metabolic process 25
              negative regulation by host of viral glycoprotein metabolic process 2
              negative regulation of elastin catabolic process 1
              negative regulation of glycoprotein biosynthetic process + 22
Path 2
Term Annotations click to browse term
  biological_process 28626
    biological regulation 13468
      regulation of biological process 13028
        regulation of cellular process 12647
          regulation of metabolic process 6959
            regulation of macromolecule metabolic process 6429
              regulation of protein metabolic process 2174
                regulation of glycoprotein metabolic process 59
                  negative regulation of glycoprotein metabolic process 25
                    negative regulation by host of viral glycoprotein metabolic process 2
                    negative regulation of elastin catabolic process 1
                    negative regulation of glycoprotein biosynthetic process + 22
paths to the root