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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of glycoprotein metabolic process
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Accession:GO:1903019 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process.
Comment:human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein
Synonyms:exact_synonym: down regulation of glycoprotein metabolic process;   down regulation of glycoprotein metabolism;   downregulation of glycoprotein metabolic process;   downregulation of glycoprotein metabolism;   negative regulation of glycoprotein metabolism
 narrow_synonym: inhibition of glycoprotein metabolic process;   inhibition of glycoprotein metabolism


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negative regulation of glycoprotein metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apcs amyloid P component, serum involved_in ISO (PMID:23544079) RGD PMID:23544079 NCBI chr13:85,373,338...85,374,134
Ensembl chr13:85,373,220...85,374,298 		JBrowse link
G Ptx3 pentraxin 3 involved_in ISO (PMID:23544079) RGD PMID:23544079 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323 		JBrowse link
negative regulation by host of viral glycoprotein metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apcs amyloid P component, serum involved_in IEA
ISO		 GO_REF:0000107
(PMID:23544079)		 Ensembl
RGD		 PMID:23544079 GO_REF:0000107 NCBI chr13:85,373,338...85,374,134
Ensembl chr13:85,373,220...85,374,298 		JBrowse link
G Ptx3 pentraxin 3 involved_in ISO (PMID:23544079) RGD PMID:23544079 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323 		JBrowse link
negative regulation of amyloid precursor protein biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aatf apoptosis antagonizing transcription factor acts_upstream_of_or_within ISO (MGI:3028747|PMID:14627703) RGD PMID:14627703 MGI:3028747 NCBI chr10:69,299,029...69,392,207
Ensembl chr10:69,299,037...69,392,201 		JBrowse link
G Abca7 ATP binding cassette subfamily A member 7 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5553242|PMID:18429932)		 Alzheimers_University_of_Toronto
RGD		 PMID:18429932 GO_REF:0000024 MGI:5553242 NCBI chr 7:9,691,452...9,711,466
Ensembl chr 7:9,691,449...9,711,425 		JBrowse link
G Ago2 argonaute RISC catalytic component 2 involved_in IMP PMID:20395292 ARUK-UCL PMID:20395292 RGD:14390059 NCBI chr 7:105,018,202...105,105,120
Ensembl chr 7:105,029,120...105,104,974 		JBrowse link
G Bace2 beta-secretase 2 involved_in ISO
ISS		 (PMID:12801932)
GO_REF:0000024		 RGD
UniProt		 PMID:12801932 GO_REF:0000024 NCBI chr11:36,707,473...36,789,550
Ensembl chr11:36,707,458...36,789,546 		JBrowse link
G Itm2a integral membrane protein 2A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:72,486,383...72,492,344
Ensembl chr  X:72,486,381...72,492,363 		JBrowse link
G Itm2b integral membrane protein 2B involved_in ISO
IBA
ISS		 (PMID:16027166), (PMID:18524908)
PMID:21873635
GO_REF:0000024		 RGD
UniProt		 PMID:16027166 PMID:18524908 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr15:48,545,998...48,568,904
Ensembl chr15:48,546,001...48,568,917 		JBrowse link
G Itm2c integral membrane protein 2C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:86,545,927...86,559,745
Ensembl chr 9:86,545,921...86,559,742 		JBrowse link
G Mir106a microRNA 106a involved_in ISO (PMID:18684319) RGD PMID:18684319 NCBI chr  X:132,422,584...132,422,661
Ensembl chr  X:132,422,584...132,422,661 		JBrowse link
G Mir144 microRNA 144 involved_in ISO (PMID:27329039) RGD PMID:27329039 NCBI chr10:62,961,348...62,961,430
Ensembl chr10:62,961,348...62,961,430 		JBrowse link
G Mir153 microRNA 153 involved_in ISO (PMID:21982160) RGD PMID:21982160 NCBI chr 6:138,163,595...138,163,681
Ensembl chr 6:138,163,595...138,163,681 		JBrowse link
G Mir17 microRNA 17 involved_in ISO (PMID:21982160) RGD PMID:21982160 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712 		JBrowse link
G Mir20a microRNA 20a involved_in ISO (PMID:21982160) RGD PMID:21982160 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168 		JBrowse link
G Mir298 microRNA 298 involved_in ISO (PMID:31942037) RGD PMID:31942037 NCBI chr 3:163,052,291...163,052,372
Ensembl chr 3:163,052,291...163,052,372 		JBrowse link
G Mir31 microRNA 31 involved_in ISO UniProtKB:P05067 (PMID:32069773) RGD PMID:32069773 NCBI chr 5:103,599,038...103,599,143 JBrowse link
G Mir323 microRNA 323 involved_in ISO (PMID:21982160) RGD PMID:21982160 NCBI chr 6:128,725,539...128,725,624
Ensembl chr 6:128,725,539...128,725,624 		JBrowse link
G Mir455 microRNA 455 involved_in ISO (PMID:31181293) RGD PMID:31181293 NCBI chr 5:76,689,313...76,689,390
Ensembl chr 5:76,689,313...76,689,390 		JBrowse link
negative regulation of CD4 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot8 acyl-CoA thioesterase 8 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:9153233)		 UniProt
Ensembl
RGD		 PMID:9153233 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:153,531,192...153,542,851
Ensembl chr 3:153,531,193...153,542,851 		JBrowse link
negative regulation of elastin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hbegf heparin-binding EGF-like growth factor involved_in IDA PMID:12882762 UniProt PMID:12882762 RGD:8554842 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441 		JBrowse link
negative regulation of elastin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst3 cystatin C involved_in ISO (PMID:10545518) RGD PMID:10545518 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822 		JBrowse link
negative regulation of FasL production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jak3 Janus kinase 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3655405|PMID:9498750)		 BHF-UCL
RGD		 PMID:9498750 GO_REF:0000024 MGI:3655405 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
negative regulation of glycoprotein biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir144 microRNA 144 acts_upstream_of ISO (PMID:27785072) RGD PMID:27785072 NCBI chr10:62,961,348...62,961,430
Ensembl chr10:62,961,348...62,961,430 		JBrowse link
negative regulation of protein glycosylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mgat4d MGAT4 family, member D involved_in ISO (MGI:5887193|PMID:20805325) RGD PMID:20805325 MGI:5887193 NCBI chr19:24,740,068...24,777,012
Ensembl chr19:24,740,078...24,777,012 		JBrowse link
G Oga O-GlcNAcase IMP RGD PMID:16332679 RGD:2305959 NCBI chr 1:244,598,285...244,633,835
Ensembl chr 1:244,598,292...244,634,359 		JBrowse link
negative regulation of proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc2a10 solute carrier family 2 member 10 acts_upstream_of_or_within ISO (PMID:16550171) RGD PMID:16550171 NCBI chr 3:154,240,395...154,252,690
Ensembl chr 3:154,240,391...154,252,690 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18877
    metabolic process 11591
      negative regulation of metabolic process 3316
        negative regulation of cellular metabolic process 2388
          negative regulation of glycoprotein metabolic process 25
            negative regulation by host of viral glycoprotein metabolic process 2
            negative regulation of elastin catabolic process 1
            negative regulation of glycoprotein biosynthetic process + 22
Path 2
Term Annotations click to browse term
  biological_process 18877
    biological regulation 13380
      regulation of biological process 12644
        regulation of metabolic process 6787
          negative regulation of metabolic process 3316
            negative regulation of macromolecule metabolic process 3084
              negative regulation of protein metabolic process 1220
                negative regulation of glycoprotein metabolic process 25
                  negative regulation by host of viral glycoprotein metabolic process 2
                  negative regulation of elastin catabolic process 1
                  negative regulation of glycoprotein biosynthetic process + 22
paths to the root