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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of glycoprotein metabolic process
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Accession:GO:1903019 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process.
Comment:human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein
Synonyms:exact_synonym: down regulation of glycoprotein metabolic process;   down regulation of glycoprotein metabolism;   downregulation of glycoprotein metabolic process;   downregulation of glycoprotein metabolism;   negative regulation of glycoprotein metabolism
 narrow_synonym: inhibition of glycoprotein metabolic process;   inhibition of glycoprotein metabolism


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negative regulation of glycoprotein metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apcs amyloid P component, serum involved_in ISO (PMID:23544079) RGD PMID:23544079 NCBI chr13:91,426,621...91,427,417
Ensembl chr13:91,426,479...91,427,575
JBrowse link
G Ptx3 pentraxin 3 involved_in ISO (PMID:23544079) RGD PMID:23544079 NCBI chr 2:158,097,843...158,103,653
Ensembl chr 2:158,097,843...158,103,653
JBrowse link
negative regulation by host of viral glycoprotein metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apcs amyloid P component, serum involved_in IEA
ISO
GO_REF:0000107
(PMID:23544079)
Ensembl
RGD
PMID:23544079 GO_REF:0000107 NCBI chr13:91,426,621...91,427,417
Ensembl chr13:91,426,479...91,427,575
JBrowse link
G Ptx3 pentraxin 3 involved_in ISO (PMID:23544079) RGD PMID:23544079 NCBI chr 2:158,097,843...158,103,653
Ensembl chr 2:158,097,843...158,103,653
JBrowse link
negative regulation of amyloid precursor protein biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aatf apoptosis antagonizing transcription factor acts_upstream_of_or_within ISO (MGI:3028747|PMID:14627703) RGD PMID:14627703 MGI:3028747 NCBI chr10:71,744,648...71,837,851
Ensembl chr10:71,744,659...71,837,851
JBrowse link
G Abca7 ATP binding cassette subfamily A member 7 involved_in ISS
ISO
GO_REF:0000024
(MGI:5553242|PMID:18429932)
Alzheimers_University_of_Toronto
RGD
PMID:18429932 GO_REF:0000024 MGI:5553242 NCBI chr 7:12,742,433...12,762,423
Ensembl chr 7:12,742,433...12,762,341
JBrowse link
G Ago2 argonaute RISC catalytic component 2 involved_in IMP PMID:20395292 ARUK-UCL PMID:20395292 RGD:14390059 NCBI chr 7:114,339,607...114,377,277
Ensembl chr 7:114,339,434...114,380,613
JBrowse link
G Bace2 beta-secretase 2 involved_in ISO
ISS
(PMID:12801932)
GO_REF:0000024
RGD
UniProt
PMID:12801932 GO_REF:0000024 NCBI chr11:37,798,397...37,880,624
Ensembl chr11:37,798,370...37,880,821
JBrowse link
G Itm2a integral membrane protein 2A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:78,490,872...78,496,814
Ensembl chr  X:78,490,866...78,496,847
JBrowse link
G Itm2b integral membrane protein 2B involved_in ISO
IBA
ISS
(PMID:16027166), (PMID:18524908)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:16027166 PMID:18524908, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr15:55,254,703...55,277,713
Ensembl chr15:55,254,706...55,277,713
JBrowse link
G Itm2c integral membrane protein 2C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:92,916,469...92,930,306
Ensembl chr 9:92,916,469...92,930,279
JBrowse link
negative regulation of CD4 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot8 acyl-CoA thioesterase 8 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:9153233)
UniProt
Ensembl
RGD
PMID:9153233 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:161,260,837...161,272,495
Ensembl chr 3:161,259,735...161,272,460
JBrowse link
negative regulation of elastin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hbegf heparin-binding EGF-like growth factor involved_in IDA PMID:12882762 UniProt PMID:12882762 RGD:8554842 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
negative regulation of elastin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst3 cystatin C involved_in ISO (PMID:10545518) RGD PMID:10545518 NCBI chr 3:143,219,671...143,223,544
Ensembl chr 3:143,219,686...143,223,615
JBrowse link
negative regulation of FasL production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jak3 Janus kinase 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:3655405|PMID:9498750)
BHF-UCL
RGD
PMID:9498750 GO_REF:0000024 MGI:3655405 NCBI chr16:20,107,471...20,120,678
Ensembl chr16:20,109,200...20,120,668
JBrowse link
negative regulation of protein glycosylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mgat4d MGAT4 family, member D involved_in ISO (MGI:5887193|PMID:20805325) RGD PMID:20805325 MGI:5887193 NCBI chr19:24,494,366...24,534,039
Ensembl chr19:24,496,569...24,532,772
JBrowse link
G Oga O-GlcNAcase IMP RGD PMID:16332679 RGD:2305959 NCBI chr 1:265,506,752...265,542,452
Ensembl chr 1:265,507,451...265,542,276
JBrowse link
negative regulation of protein glycosylation in Golgi term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer2 alkaline ceramidase 2 involved_in ISO (PMID:20089856) RGD PMID:20089856 NCBI chr 5:105,230,540...105,279,732
Ensembl chr 5:105,230,580...105,279,731
JBrowse link
G Tmem59 transmembrane protein 59 involved_in ISO (PMID:20427278) RGD PMID:20427278 NCBI chr 5:126,783,061...126,804,177
Ensembl chr 5:126,783,061...126,804,175
JBrowse link
negative regulation of proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc2a10 solute carrier family 2 member 10 acts_upstream_of_or_within ISO (PMID:16550171) RGD PMID:16550171 NCBI chr 3:162,182,156...162,194,610
Ensembl chr 3:162,181,974...162,194,804
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19638
    metabolic process 11894
      negative regulation of metabolic process 3194
        negative regulation of cellular metabolic process 2673
          negative regulation of glycoprotein metabolic process 18
            negative regulation by host of viral glycoprotein metabolic process 2
            negative regulation of elastin catabolic process 1
            negative regulation of glycoprotein biosynthetic process + 15
Path 2
Term Annotations click to browse term
  biological_process 19638
    biological regulation 13583
      regulation of biological process 12829
        regulation of metabolic process 6789
          negative regulation of metabolic process 3194
            negative regulation of macromolecule metabolic process 2957
              negative regulation of protein metabolic process 1155
                negative regulation of glycoprotein metabolic process 18
                  negative regulation by host of viral glycoprotein metabolic process 2
                  negative regulation of elastin catabolic process 1
                  negative regulation of glycoprotein biosynthetic process + 15
paths to the root