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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of glycoprotein metabolic process
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Accession:GO:1903019 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process.
Comment:human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein
Synonyms:exact_synonym: down regulation of glycoprotein metabolic process;   down regulation of glycoprotein metabolism;   downregulation of glycoprotein metabolic process;   downregulation of glycoprotein metabolism;   negative regulation of glycoprotein metabolism
 narrow_synonym: inhibition of glycoprotein metabolic process;   inhibition of glycoprotein metabolism


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negative regulation of glycoprotein metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apcs amyloid P component, serum involved_in ISO
IEA 		(PMID:23544079)
GO_REF:0000107 		RGD
Ensembl		 PMID:23544079 GO_REF:0000107 NCBI chr13:85,373,219...85,374,195
Ensembl chr13:85,373,220...85,374,298 		JBrowse link
G Ptx3 pentraxin 3 involved_in ISO (PMID:23544079) RGD PMID:23544079 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323 		JBrowse link
negative regulation by host of viral glycoprotein metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apcs amyloid P component, serum involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr13:85,373,219...85,374,195
Ensembl chr13:85,373,220...85,374,298 		JBrowse link
negative regulation of amyloid precursor protein biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aatf apoptosis antagonizing transcription factor acts_upstream_of_or_within ISO (PMID:14627703) RGD PMID:14627703 NCBI chr10:69,299,029...69,392,207
Ensembl chr10:69,299,037...69,392,201 		JBrowse link
G Abca7 ATP binding cassette subfamily A member 7 involved_in ISS
ISO 		GO_REF:0000024
(PMID:18429932) 		Alzheimers_University_of_Toronto
RGD		 PMID:18429932 GO_REF:0000024 NCBI chr 7:9,691,452...9,711,466
Ensembl chr 7:9,691,449...9,711,425 		JBrowse link
G Ago2 argonaute RISC catalytic component 2 involved_in IMP PMID:20395292 ARUK-UCL PMID:20395292 RGD:14390059 NCBI chr 7:105,018,202...105,105,118
Ensembl chr 7:105,029,120...105,104,974 		JBrowse link
G Bace2 beta-secretase 2 involved_in ISO
ISS 		(PMID:12801932)
GO_REF:0000024 		RGD
UniProt		 PMID:12801932 GO_REF:0000024 NCBI chr11:36,707,447...36,789,550
Ensembl chr11:36,707,458...36,789,546 		JBrowse link
G Itm2b integral membrane protein 2B involved_in ISO
IBA
IEA
ISS 		(PMID:16027166), (PMID:18524908)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024 		RGD
GO_Central
Ensembl
UniProt		 PMID:16027166 PMID:18524908 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr15:48,545,998...48,568,904
Ensembl chr15:48,546,001...48,568,917 		JBrowse link
G Itm2c integral membrane protein 2C involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:86,545,927...86,559,745
Ensembl chr 9:86,545,921...86,559,742 		JBrowse link
G Mir106a microRNA 106a involved_in ISO (PMID:18684319) RGD PMID:18684319 NCBI chr  X:132,422,584...132,422,661
Ensembl chr  X:132,422,584...132,422,661 		JBrowse link
G Mir144 microRNA 144 involved_in ISO (PMID:27329039) RGD PMID:27329039 NCBI chr10:62,961,348...62,961,430
Ensembl chr10:62,961,348...62,961,430 		JBrowse link
G Mir153 microRNA 153 involved_in ISO (PMID:21982160) RGD PMID:21982160 NCBI chr 6:138,163,595...138,163,681
Ensembl chr 6:138,163,595...138,163,681 		JBrowse link
G Mir17 microRNA 17 involved_in ISO (PMID:21982160) RGD PMID:21982160 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712 		JBrowse link
G Mir20a microRNA 20a involved_in ISO (PMID:21982160) RGD PMID:21982160 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168 		JBrowse link
G Mir298 microRNA 298 involved_in ISO (PMID:31942037) RGD PMID:31942037 NCBI chr 3:163,052,291...163,052,372
Ensembl chr 3:163,052,291...163,052,372 		JBrowse link
G Mir31 microRNA 31 involved_in ISO UniProtKB:P05067 (PMID:32069773) RGD PMID:32069773 NCBI chr 5:103,599,038...103,599,143 JBrowse link
G Mir323 microRNA 323 involved_in ISO (PMID:21982160) RGD PMID:21982160 NCBI chr 6:128,725,539...128,725,624
Ensembl chr 6:128,725,539...128,725,624 		JBrowse link
G Mir455 microRNA 455 involved_in ISO (PMID:31181293) RGD PMID:31181293 NCBI chr 5:76,689,313...76,689,390
Ensembl chr 5:76,689,313...76,689,390 		JBrowse link
negative regulation of elastin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst3 cystatin C involved_in ISO (PMID:10545518) RGD PMID:10545518 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822 		JBrowse link
negative regulation of glycoprotein biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot8 acyl-CoA thioesterase 8 involved_in ISS
ISO 		GO_REF:0000024
(PMID:9153233) 		UniProt
RGD		 PMID:9153233 GO_REF:0000024 NCBI chr 3:153,531,192...153,542,851
Ensembl chr 3:153,531,193...153,542,851 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor involved_in IDA PMID:12882762 UniProt PMID:12882762 RGD:8554842 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441 		JBrowse link
G Jak3 Janus kinase 3 involved_in ISS
ISO 		GO_REF:0000024
(PMID:9498750) 		BHF-UCL
RGD		 PMID:9498750 GO_REF:0000024 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
G Mir144 microRNA 144 acts_upstream_of ISO (PMID:27785072) RGD PMID:27785072 NCBI chr10:62,961,348...62,961,430
Ensembl chr10:62,961,348...62,961,430 		JBrowse link
negative regulation of protein glycosylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mgat4d MGAT4 family, member D involved_in ISO
IEA 		(PMID:20805325)
GO_REF:0000107 		RGD
Ensembl		 PMID:20805325 GO_REF:0000107 NCBI chr19:24,740,068...24,777,012
Ensembl chr19:24,740,078...24,777,012 		JBrowse link
G Oga O-GlcNAcase IMP RGD PMID:16332679 RGD:2305959 NCBI chr 1:254,547,311...254,589,596
Ensembl chr 1:244,598,292...244,634,359 		JBrowse link
negative regulation of proteoglycan biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc2a10 solute carrier family 2 member 10 acts_upstream_of_or_within ISO
IEA 		(PMID:16550171)
GO_REF:0000107 		RGD
Ensembl		 PMID:16550171 GO_REF:0000107 NCBI chr 3:154,240,395...154,252,690
Ensembl chr 3:154,240,391...154,252,690 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        carbohydrate derivative metabolic process 1062
          glycoprotein metabolic process 399
            negative regulation of glycoprotein metabolic process 24
              negative regulation by host of viral glycoprotein metabolic process 1
              negative regulation of elastin catabolic process 1
              negative regulation of glycoprotein biosynthetic process + 21
Path 2
Term Annotations click to browse term
  biological_process 20543
    biological regulation 13835
      regulation of biological process 13398
        regulation of cellular process 13032
          regulation of metabolic process 6776
            regulation of macromolecule metabolic process 6244
              regulation of protein metabolic process 1968
                regulation of glycoprotein metabolic process 57
                  negative regulation of glycoprotein metabolic process 24
                    negative regulation by host of viral glycoprotein metabolic process 1
                    negative regulation of elastin catabolic process 1
                    negative regulation of glycoprotein biosynthetic process + 21
paths to the root