Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of amyloid precursor protein catabolic process
go back to main search page
Accession:GO:1902991 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of amyloid precursor protein catabolic process.
Comment:An example of this is human FKBP1A/12 (UniProt symbol P62942) in PMID:24499793 (inferred from direct assay).
Synonyms:exact_synonym: regulation of APP catabolic process;   regulation of APP catabolism;   regulation of amyloid precursor protein breakdown;   regulation of amyloid precursor protein catabolism;   regulation of amyloid precursor protein degradation


show annotations for term's descendants           Sort by:
regulation of amyloid precursor protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP-binding cassette, sub-family A member 7 involved_in ISO GO_Central GO_REF:0000119 NCBI chr10:79,832,328...79,851,406
Ensembl chr10:79,832,328...79,851,406 		JBrowse link
G Apoe apolipoprotein E involved_in ISO GO_Central GO_REF:0000119 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Chrna7 cholinergic receptor, nicotinic, alpha polypeptide 7 involved_in ISO (PMID:20708605) ARUK-UCL PMID:20708605 NCBI chr 7:62,748,440...62,862,274
Ensembl chr 7:62,748,440...62,862,317 		JBrowse link
G Fkbp1a FK506 binding protein 1a involved_in ISO (PMID:24499793) ParkinsonsUK-UCL PMID:24499793 NCBI chr 2:151,384,403...151,403,611
Ensembl chr 2:151,384,403...151,403,612 		JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein involved_in ISS
ISO 		Alzheimers_University_of_Toronto
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr 7:89,778,711...89,858,655
Ensembl chr 7:89,779,421...89,862,673 		JBrowse link
G Unc13a unc-13 homolog A involved_in IMP (PMID:23070049) ParkinsonsUK-UCL PMID:23070049 NCBI chr 8:72,079,356...72,124,418
Ensembl chr 8:72,077,061...72,124,401 		JBrowse link
negative regulation of amyloid precursor protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flot2 flotillin 2 involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr11:77,928,757...77,951,260
Ensembl chr11:77,928,757...77,951,260 		JBrowse link
G Mir15b microRNA 15b acts_upstream_of ISO (PMID:29961672) ARUK-UCL PMID:29961672 NCBI chr 3:68,917,105...68,917,168
Ensembl chr 3:68,917,105...68,917,168 		JBrowse link
G Mir29a microRNA 29a acts_upstream_of ISO (PMID:18434550) ARUK-UCL PMID:18434550 NCBI chr 6:31,039,595...31,039,682
Ensembl chr 6:31,039,595...31,039,682 		JBrowse link
G Mir29b-1 microRNA 29b-1 acts_upstream_of ISO (PMID:18434550) ARUK-UCL PMID:18434550 NCBI chr 6:31,039,958...31,040,028
Ensembl chr 6:31,039,958...31,040,028 		JBrowse link
G Mir29b-2 microRNA 29b-2 acts_upstream_of ISO (PMID:18434550) ARUK-UCL PMID:18434550 NCBI chr 1:194,719,348...194,719,428
Ensembl chr 1:194,719,348...194,719,428 		JBrowse link
G Prnp prion protein involved_in IGI (PMID:17573534) ARUK-UCL PMID:17573534 NCBI chr 2:131,751,848...131,780,356
Ensembl chr 2:131,751,848...131,780,349 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr18:10,064,401...10,182,225
Ensembl chr18:10,064,401...10,182,045 		JBrowse link
G Sorl1 sortilin-related receptor, LDLR class A repeats-containing involved_in IMP
ISO 		(PMID:18362153) Alzheimers_University_of_Toronto
GO_Central		 PMID:18362153 GO_REF:0000119 NCBI chr 9:41,876,005...42,035,593
Ensembl chr 9:41,876,016...42,035,593 		JBrowse link
negative regulation of amyloid-beta formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP-binding cassette, sub-family A member 7 involved_in IDA
IMP 		(PMID:18429932)
(PMID:23467355), (PMID:27030769) 		Alzheimers_University_of_Toronto PMID:18429932 PMID:23467355 PMID:27030769 NCBI chr10:79,832,328...79,851,406
Ensembl chr10:79,832,328...79,851,406 		JBrowse link
G Apoe apolipoprotein E involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Bin1 bridging integrator 1 involved_in IMP
ISO 		(PMID:27179792) ARUK-UCL
GO_Central		 PMID:27179792 GO_REF:0000119 NCBI chr18:32,509,671...32,568,793
Ensembl chr18:32,510,283...32,568,790 		JBrowse link
G Chrna7 cholinergic receptor, nicotinic, alpha polypeptide 7 involved_in ISO (PMID:20708605) ARUK-UCL PMID:20708605 NCBI chr 7:62,748,440...62,862,274
Ensembl chr 7:62,748,440...62,862,317 		JBrowse link
G Clu clusterin involved_in ISS
ISO 		Alzheimers_University_of_Toronto
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr14:66,206,093...66,218,992
Ensembl chr14:66,205,932...66,218,996 		JBrowse link
G Gga3 golgi associated, gamma adaptin ear containing, ARF binding protein 3 involved_in ISO
ISS 		GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr11:115,475,081...115,495,501
Ensembl chr11:115,475,081...115,494,877 		JBrowse link
G Hap1 huntingtin-associated protein 1 involved_in ISS
ISO 		UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000096 NCBI chr11:100,238,153...100,247,808
Ensembl chr11:100,238,153...100,246,954 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904 		JBrowse link
G Mir103-1 microRNA 103-1 acts_upstream_of ISO (PMID:27343180) ARUK-UCL PMID:27343180 NCBI chr11:35,673,223...35,673,308
Ensembl chr11:35,673,223...35,673,308 		JBrowse link
G Mir103-2 microRNA 103-2 acts_upstream_of ISO (PMID:27343180) ARUK-UCL PMID:27343180 NCBI chr 2:131,129,972...131,130,057
Ensembl chr 2:131,129,972...131,130,057 		JBrowse link
G Mir153 microRNA 153 involved_in ISO (PMID:22733824) ARUK-UCL PMID:22733824 NCBI chr12:117,214,437...117,214,505
Ensembl chr12:117,214,437...117,214,505 		JBrowse link
G Mir15a microRNA 15a acts_upstream_of ISO (PMID:27343180) ARUK-UCL PMID:27343180 NCBI chr14:61,869,476...61,869,559
Ensembl chr14:61,869,476...61,869,559 		JBrowse link
G Mir15b microRNA 15b acts_upstream_of ISO (PMID:29961672) ARUK-UCL PMID:29961672 NCBI chr 3:68,917,105...68,917,168
Ensembl chr 3:68,917,105...68,917,168 		JBrowse link
G Mir16-1 microRNA 16-1 acts_upstream_of ISO (PMID:27343180) ARUK-UCL PMID:27343180 NCBI chr14:61,869,329...61,869,421
Ensembl chr14:61,869,329...61,869,421 		JBrowse link
G Mir16-2 microRNA 16-2 acts_upstream_of ISO (PMID:27343180) ARUK-UCL PMID:27343180 NCBI chr 3:68,917,235...68,917,329
Ensembl chr 3:68,917,235...68,917,329 		JBrowse link
G Mir186 microRNA 186 acts_upstream_of ISO (PMID:25100943) ARUK-UCL PMID:25100943 NCBI chr 3:157,249,916...157,249,986
Ensembl chr 3:157,249,916...157,249,986 		JBrowse link
G Mir24-1 microRNA 24-1 acts_upstream_of ISO (PMID:25100943) ARUK-UCL PMID:25100943 NCBI chr13:63,449,022...63,449,089
Ensembl chr13:63,449,022...63,449,089 		JBrowse link
G Mir24-2 microRNA 24-2 acts_upstream_of ISO (PMID:25100943) ARUK-UCL PMID:25100943 NCBI chr 8:84,935,444...84,935,550
Ensembl chr 8:84,935,444...84,935,550 		JBrowse link
G Mir298 microRNA 298 acts_upstream_of ISO (PMID:31942037) ARUK-UCL PMID:31942037 NCBI chr 2:174,109,297...174,109,378
Ensembl chr 2:174,109,297...174,109,378 		JBrowse link
G Mir29a microRNA 29a acts_upstream_of ISO (PMID:18434550) ARUK-UCL PMID:18434550 NCBI chr 6:31,039,595...31,039,682
Ensembl chr 6:31,039,595...31,039,682 		JBrowse link
G Mir29b-1 microRNA 29b-1 acts_upstream_of ISO (PMID:18434550) ARUK-UCL PMID:18434550 NCBI chr 6:31,039,958...31,040,028
Ensembl chr 6:31,039,958...31,040,028 		JBrowse link
G Mir29b-2 microRNA 29b-2 acts_upstream_of ISO (PMID:18434550) ARUK-UCL PMID:18434550 NCBI chr 1:194,719,348...194,719,428
Ensembl chr 1:194,719,348...194,719,428 		JBrowse link
G Mir29c microRNA 29c acts_upstream_of ISO (PMID:25973041) ARUK-UCL PMID:25973041 NCBI chr 1:194,719,855...194,719,942
Ensembl chr 1:194,719,855...194,719,942 		JBrowse link
G Mir339 microRNA 339 acts_upstream_of ISO (PMID:24352696) ARUK-UCL PMID:24352696 NCBI chr 5:139,355,405...139,355,500
Ensembl chr 5:139,355,405...139,355,500 		JBrowse link
G Mir361 microRNA 361 involved_in ISO (PMID:31601077) ARUK-UCL PMID:31601077 NCBI chr  X:111,984,521...111,984,590
Ensembl chr  X:111,984,521...111,984,590 		JBrowse link
G Mir455 microRNA 455 acts_upstream_of ISO (PMID:25100943), (PMID:31181293) ARUK-UCL PMID:25100943 PMID:31181293 NCBI chr 4:63,175,088...63,175,169
Ensembl chr 4:63,175,088...63,175,169 		JBrowse link
G Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 involved_in
acts_upstream_of_or_within 		IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr13:58,954,363...59,281,782
Ensembl chr13:58,954,383...59,281,784 		JBrowse link
G Pin1 peptidyl-prolyl cis/trans isomerase, NIMA-interacting 1 involved_in ISO
ISS
IMP 		(PMID:16554819) GO_Central
UniProt		 PMID:16554819 GO_REF:0000024 GO_REF:0000119 NCBI chr 9:20,563,335...20,575,008
Ensembl chr 9:20,563,391...20,577,880 		JBrowse link
G Pin1rt1 peptidyl-prolyl cis/trans isomerase, NIMA-interacting 1, retrogene 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 2:104,544,232...104,546,707
Ensembl chr 2:104,544,271...104,546,724 		JBrowse link
G Prnp prion protein involved_in IGI (PMID:17573534) ARUK-UCL PMID:17573534 NCBI chr 2:131,751,848...131,780,356
Ensembl chr 2:131,751,848...131,780,349 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr18:10,064,401...10,182,225
Ensembl chr18:10,064,401...10,182,045 		JBrowse link
G Rps23rg1 ribosomal protein S23, retrogene 1 acts_upstream_of_or_within IDA (PMID:19914182) MGI PMID:19914182 NCBI chr 8:3,617,998...3,634,776
Ensembl chr 8:3,617,990...3,634,939 		JBrowse link
G Rtn1 reticulon 1 involved_in ISS
ISO 		UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr12:72,258,523...72,455,828
Ensembl chr12:72,258,526...72,455,828 		JBrowse link
G Rtn2 reticulon 2 (Z-band associated protein) involved_in ISO
ISS 		GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 7:19,016,549...19,030,089
Ensembl chr 7:19,016,549...19,030,085 		JBrowse link
G Rtn3 reticulon 3 involved_in ISS
ISO 		UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr19:7,403,260...7,460,656
Ensembl chr19:7,403,266...7,460,646 		JBrowse link
G Rtn4 reticulon 4 involved_in ISS
ISO 		UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr11:29,642,898...29,694,414
Ensembl chr11:29,642,947...29,694,331 		JBrowse link
G Sorl1 sortilin-related receptor, LDLR class A repeats-containing involved_in IMP
ISO 		(PMID:18362153), (PMID:19036982) Alzheimers_University_of_Toronto
GO_Central		 PMID:18362153 PMID:19036982 GO_REF:0000119 NCBI chr 9:41,876,005...42,035,593
Ensembl chr 9:41,876,016...42,035,593 		JBrowse link
G Spon1 spondin 1, (f-spondin) extracellular matrix protein acts_upstream_of_or_within IDA (PMID:16227578) MGI PMID:16227578 NCBI chr 7:113,365,235...113,642,610
Ensembl chr 7:113,365,235...113,642,605 		JBrowse link
negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bin1 bridging integrator 1 involved_in ISO
IMP 		(PMID:27179792) GO_Central
ARUK-UCL		 PMID:27179792 GO_REF:0000119 NCBI chr18:32,509,671...32,568,793
Ensembl chr18:32,510,283...32,568,790 		JBrowse link
G Tmed10 transmembrane p24 trafficking protein 10 acts_upstream_of_or_within IMP (PMID:16641999) MGI PMID:16641999 NCBI chr12:85,387,388...85,421,491
Ensembl chr12:85,387,388...85,421,621 		JBrowse link
positive regulation of amyloid precursor protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP-binding cassette, sub-family A member 2 acts_upstream_of ISO GO_Central GO_REF:0000119 NCBI chr 2:25,318,611...25,338,556
Ensembl chr 2:25,318,715...25,338,552 		JBrowse link
G Ager advanced glycosylation end product-specific receptor involved_in ISO (PMID:22406537) ARUK-UCL PMID:22406537 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910 		JBrowse link
G App amyloid beta precursor protein involved_in ISO GO_Central GO_REF:0000119 NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654 		JBrowse link
G Efna1 ephrin A1 involved_in ISO (PMID:24217950) ARUK-UCL PMID:24217950 NCBI chr 3:89,179,037...89,188,258
Ensembl chr 3:89,179,040...89,188,449 		JBrowse link
G Efna3 ephrin A3 involved_in ISO (PMID:24217950) ARUK-UCL PMID:24217950 NCBI chr 3:89,221,200...89,231,359
Ensembl chr 3:89,221,206...89,230,272 		JBrowse link
G Epha4 Eph receptor A4 involved_in ISO (PMID:24217950) ARUK-UCL PMID:24217950 NCBI chr 1:77,343,819...77,491,763
Ensembl chr 1:77,343,822...77,491,725 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:24217950) ARUK-UCL PMID:24217950 NCBI chr 4:3,676,865...3,791,613
Ensembl chr 4:3,678,115...3,813,122 		JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein involved_in IMP (PMID:22539346) Alzheimers_University_of_Toronto PMID:22539346 NCBI chr 7:89,778,711...89,858,655
Ensembl chr 7:89,779,421...89,862,673 		JBrowse link
G Ranbp9 RAN binding protein 9 acts_upstream_of ISO GO_Central GO_REF:0000096 NCBI chr13:43,556,151...43,634,949
Ensembl chr13:43,556,151...43,634,758 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in IMP
ISO 		(PMID:24305806) ARUK-UCL
GO_Central		 PMID:24305806 GO_REF:0000119 NCBI chr12:16,944,808...17,038,275
Ensembl chr12:16,944,896...17,037,824 		JBrowse link
G Spon1 spondin 1, (f-spondin) extracellular matrix protein acts_upstream_of_or_within IDA (PMID:16227578) MGI PMID:16227578 NCBI chr 7:113,365,235...113,642,610
Ensembl chr 7:113,365,235...113,642,605 		JBrowse link
positive regulation of amyloid-beta formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP-binding cassette, sub-family A member 2 involved_in
acts_upstream_of 		ISO GO_Central GO_REF:0000096 GO_REF:0000119 NCBI chr 2:25,318,611...25,338,556
Ensembl chr 2:25,318,715...25,338,552 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr17:31,276,668...31,336,958
Ensembl chr17:31,276,649...31,336,962 		JBrowse link
G Apoe apolipoprotein E involved_in ISO GO_Central GO_REF:0000119 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Casp3 caspase 3 involved_in ISS
ISO 		UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000096 GO_REF:0000119 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Chrna7 cholinergic receptor, nicotinic, alpha polypeptide 7 involved_in IGI (PMID:20164328) ARUK-UCL PMID:20164328 NCBI chr 7:62,748,440...62,862,274
Ensembl chr 7:62,748,440...62,862,317 		JBrowse link
G Clu clusterin involved_in IMP (PMID:12145324) Alzheimers_University_of_Toronto PMID:12145324 NCBI chr14:66,206,093...66,218,992
Ensembl chr14:66,205,932...66,218,996 		JBrowse link
G Csnk1e casein kinase 1, epsilon involved_in ISO
IEA 		RGD
Ensembl
GO_Central		 PMID:17360493 GO_REF:0000096 GO_REF:0000107 RGD:10395238 NCBI chr15:79,302,054...79,339,779
Ensembl chr15:79,302,056...79,339,767 		JBrowse link
G Efna1 ephrin A1 involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 3:89,179,037...89,188,258
Ensembl chr 3:89,179,040...89,188,449 		JBrowse link
G Epha4 Eph receptor A4 involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 1:77,343,819...77,491,763
Ensembl chr 1:77,343,822...77,491,725 		JBrowse link
G Gsap gamma-secretase activating protein involved_in IBA
IDA
ISO 		(PMID:20811458) GO_Central
UniProt		 PMID:20811458 GO_REF:0000033 GO_REF:0000119 NCBI chr 5:21,380,767...21,518,423
Ensembl chr 5:21,391,253...21,520,130 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 7:24,927,683...24,937,276
Ensembl chr 7:24,927,683...24,937,276 		JBrowse link
G Ifng interferon gamma involved_in IDA
ISO
IGI 		(PMID:17255335) ARUK-UCL
GO_Central		 PMID:17255335 GO_REF:0000119 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Ifngr1 interferon gamma receptor 1 involved_in IGI (PMID:17255335) ARUK-UCL PMID:17255335 NCBI chr10:19,467,697...19,485,977
Ensembl chr10:19,467,697...19,485,977 		JBrowse link
G Lrrtm3 leucine rich repeat transmembrane neuronal 3 acts_upstream_of_or_within IMP
ISO 		(PMID:17098871) MGI PMID:17098871 GO_REF:0000008 NCBI chr10:63,764,276...63,926,034
Ensembl chr10:63,764,251...63,926,056 		JBrowse link
G Mir206 microRNA 206 involved_in ISO (PMID:27277332) ARUK-UCL PMID:27277332 NCBI chr 1:20,749,234...20,749,306
Ensembl chr 1:20,749,234...20,749,306 		JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein involved_in IMP
ISO 		(PMID:22539346), (PMID:24577224) Alzheimers_University_of_Toronto
GO_Central		 PMID:22539346 PMID:24577224 GO_REF:0000119 NCBI chr 7:89,778,711...89,858,655
Ensembl chr 7:89,779,421...89,862,673 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) acts_upstream_of IDA (PMID:21329555) ARUK-UCL PMID:21329555 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in IMP
ISO 		(PMID:24305806) ARUK-UCL
GO_Central		 PMID:24305806 GO_REF:0000119 NCBI chr12:16,944,808...17,038,275
Ensembl chr12:16,944,896...17,037,824 		JBrowse link
G Slc2a13 solute carrier family 2 (facilitated glucose transporter), member 13 involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr15:91,151,894...91,457,467
Ensembl chr15:91,151,899...91,457,464 		JBrowse link
G Sp1 trans-acting transcription factor 1 acts_upstream_of ISO GO_Central GO_REF:0000119 NCBI chr15:102,314,751...102,344,839
Ensembl chr15:102,314,578...102,344,839 		JBrowse link
G Tnf tumor necrosis factor involved_in IDA (PMID:17255335) ARUK-UCL PMID:17255335 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
regulation of amyloid-beta formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dyrk1a dual-specificity tyrosine phosphorylation regulated kinase 1a involved_in ISO (PMID:25556849) ARUK-UCL PMID:25556849 NCBI chr16:94,370,770...94,496,378
Ensembl chr16:94,370,869...94,496,376 		JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein NOT|involved_in IGI (PMID:26005850) ARUK-UCL PMID:26005850 NCBI chr 7:89,778,711...89,858,655
Ensembl chr 7:89,779,421...89,862,673 		JBrowse link
G Tmed10 transmembrane p24 trafficking protein 10 involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr12:85,387,388...85,421,491
Ensembl chr12:85,387,388...85,421,621 		JBrowse link
G Tmed10-ps transmembrane p24 trafficking protein 10, pseudogene involved_in ISO GO_Central GO_REF:0000119 NCBI chr13:36,174,240...36,180,221
Ensembl chr13:36,174,844...36,175,503 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28626
    regulation of biological process 13028
      regulation of cellular process 12647
        regulation of metabolic process 6959
          regulation of macromolecule metabolic process 6429
            regulation of protein metabolic process 2174
              regulation of amyloid precursor protein catabolic process 67
                negative regulation of amyloid precursor protein catabolic process + 40
                positive regulation of amyloid precursor protein catabolic process + 27
                regulation of amyloid-beta formation + 59
Path 2
Term Annotations click to browse term
  biological_process 28626
    biological regulation 13468
      regulation of biological process 13028
        regulation of cellular process 12647
          regulation of metabolic process 6959
            regulation of primary metabolic process 5767
              regulation of protein metabolic process 2174
                regulation of amyloid precursor protein catabolic process 67
                  negative regulation of amyloid precursor protein catabolic process + 40
                  positive regulation of amyloid precursor protein catabolic process + 27
                  regulation of amyloid-beta formation + 59
paths to the root