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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of amyloid precursor protein catabolic process
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Accession:GO:1902991 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of amyloid precursor protein catabolic process.
Comment:An example of this is human FKBP1A/12 (UniProt symbol P62942) in PMID:24499793 (inferred from direct assay).
Synonyms:exact_synonym: regulation of APP catabolic process;   regulation of APP catabolism;   regulation of amyloid precursor protein breakdown;   regulation of amyloid precursor protein catabolism;   regulation of amyloid precursor protein degradation



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regulation of amyloid precursor protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 involved_in ISO
IEA
ISS
(PMID:26260791)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:26260791 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:9,691,452...9,711,466
Ensembl chr 7:9,691,449...9,711,425
JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:28164773) RGD PMID:28164773 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit involved_in ISO UniProtKB:P05067 (PMID:20708605) RGD PMID:20708605 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A involved_in ISO UniProtKB:P05067 (PMID:24499793) RGD PMID:24499793 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743
JBrowse link
G Unc13a unc-13 homolog A involved_in ISO (MGI:5795815|PMID:23070049) RGD PMID:23070049 MGI:5795815 NCBI chr16:18,336,229...18,381,811
Ensembl chr16:18,336,229...18,381,872
JBrowse link
negative regulation of amyloid precursor protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flot2 flotillin 2 involved_in ISO (PMID:24612608) RGD PMID:24612608 NCBI chr10:62,926,047...62,947,759
Ensembl chr10:62,920,665...62,947,756
JBrowse link
G Mir15b microRNA 15b acts_upstream_of ISO (PMID:29961672) RGD PMID:29961672 NCBI chr 2:153,245,200...153,245,297
Ensembl chr 2:153,245,200...153,245,297
JBrowse link
G Mir29a microRNA 29a acts_upstream_of ISO (PMID:18434550) RGD PMID:18434550 NCBI chr 4:59,650,608...59,650,695 JBrowse link
G Mir29b1 microRNA 29b-1 acts_upstream_of ISO (PMID:18434550) RGD PMID:18434550 NCBI chr 4:59,650,987...59,651,067
Ensembl chr 4:59,650,986...59,651,067
JBrowse link
G Mir29b2 microRNA 29b-2 acts_upstream_of ISO (PMID:18434550) RGD PMID:18434550 NCBI chr13:106,570,371...106,570,451
Ensembl chr13:106,570,367...106,570,456
JBrowse link
G Prnp prion protein involved_in ISO UniProtKB:P12023 (MGI:3714552|PMID:17573534) RGD PMID:17573534 MGI:3714552 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in ISO (PMID:24305806), (PMID:27853422) RGD PMID:24305806 PMID:27853422 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571
JBrowse link
negative regulation of amyloid-beta formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 involved_in ISS
ISO
GO_REF:0000024
(MGI:5487687|PMID:23467355), (MGI:5553242|PMID:18429932), (MGI:5774886|PMID:27030769)
Alzheimers_University_of_Toronto
RGD
PMID:18429932 PMID:23467355 PMID:27030769 GO_REF:0000024 MGI:5487687 MGI:5553242 MGI:5774886 NCBI chr 7:9,691,452...9,711,466
Ensembl chr 7:9,691,449...9,711,425
JBrowse link
G Apoe apolipoprotein E involved_in ISO
IEA
(PMID:24259049)
GO_REF:0000107
(PMID:24154541)
RGD
Ensembl
PMID:24154541 PMID:24259049 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Bin1 bridging integrator 1 involved_in ISO
IEA
(PMID:27179792)
(MGI:5811968|PMID:27179792)
GO_REF:0000107
RGD
Ensembl
PMID:27179792 GO_REF:0000107 MGI:5811968 NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit involved_in ISO UniProtKB:P05067 (PMID:20708605) RGD PMID:20708605 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240
JBrowse link
G Clu clusterin involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:12047389), (PMID:17412999)
Alzheimers_University_of_Toronto
Ensembl
RGD
PMID:12047389 PMID:17412999 GO_REF:0000024 GO_REF:0000107 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Gga3 golgi associated, gamma adaptin ear containing, ARF binding protein 3 involved_in ISO (PMID:17553422) RGD PMID:17553422 NCBI chr10:100,825,426...100,844,462
Ensembl chr10:100,825,426...100,844,462
JBrowse link
G Hap1 huntingtin-associated protein 1 involved_in IMP PMID:22731248 UniProt PMID:22731248 RGD:10047200 NCBI chr10:85,277,890...85,286,126
Ensembl chr10:85,277,890...85,286,126
JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA
RNAcentral:URS000034B6F5_9606 (PMID:27277332)
GO_REF:0000107
RGD
Ensembl
PMID:27277332 GO_REF:0000107 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Mir153 microRNA 153 involved_in ISO (PMID:22733824) RGD PMID:22733824 NCBI chr 6:138,163,595...138,163,681
Ensembl chr 6:138,163,595...138,163,681
JBrowse link
G Mir15b microRNA 15b acts_upstream_of ISO (PMID:29961672) RGD PMID:29961672 NCBI chr 2:153,245,200...153,245,297
Ensembl chr 2:153,245,200...153,245,297
JBrowse link
G Mir186 microRNA 186 acts_upstream_of ISO (PMID:25100943) RGD PMID:25100943 NCBI chr 2:246,582,806...246,582,891
Ensembl chr 2:246,582,806...246,582,891
JBrowse link
G Mir24-2 microRNA 24-2 acts_upstream_of ISO (PMID:25100943) RGD PMID:25100943 NCBI chr19:23,954,683...23,954,790
Ensembl chr19:23,954,683...23,954,790
JBrowse link
G Mir298 microRNA 298 acts_upstream_of ISO (PMID:31942037) RGD PMID:31942037 NCBI chr 3:163,052,291...163,052,372
Ensembl chr 3:163,052,291...163,052,372
JBrowse link
G Mir29a microRNA 29a acts_upstream_of ISO (PMID:18434550) RGD PMID:18434550 NCBI chr 4:59,650,608...59,650,695 JBrowse link
G Mir29b1 microRNA 29b-1 acts_upstream_of ISO (PMID:18434550) RGD PMID:18434550 NCBI chr 4:59,650,987...59,651,067
Ensembl chr 4:59,650,986...59,651,067
JBrowse link
G Mir29b2 microRNA 29b-2 acts_upstream_of ISO (PMID:18434550) RGD PMID:18434550 NCBI chr13:106,570,371...106,570,451
Ensembl chr13:106,570,367...106,570,456
JBrowse link
G Mir339 microRNA 339 acts_upstream_of ISO (PMID:24352696) RGD PMID:24352696 NCBI chr12:15,277,546...15,277,641
Ensembl chr12:15,277,546...15,277,641
JBrowse link
G Mir361 microRNA 361 involved_in ISO (PMID:31601077) RGD PMID:31601077 NCBI chr  X:78,246,206...78,246,275
Ensembl chr  X:78,246,206...78,246,275
JBrowse link
G Mir455 microRNA 455 acts_upstream_of ISO (PMID:25100943), (PMID:31181293) RGD PMID:25100943 PMID:31181293 NCBI chr 5:76,689,313...76,689,390
Ensembl chr 5:76,689,313...76,689,390
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
UniProtKB:P05067-4 (PMID:26094765)
Ensembl
RGD
PMID:26094765 GO_REF:0000107 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
JBrowse link
G Olfm1 olfactomedin 1 acts_upstream_of_or_within ISO (MGI:5444053|PMID:22992957) RGD PMID:22992957 MGI:5444053 NCBI chr 3:11,520,522...11,558,240
Ensembl chr 3:11,520,729...11,558,239
JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 involved_in ISO (PMID:25576397)
(MGI:3620333|PMID:16554819)
RGD PMID:16554819 PMID:25576397 MGI:3620333 NCBI chr 8:19,189,408...19,200,785
Ensembl chr 8:19,189,373...19,200,785
JBrowse link
G Prnp prion protein involved_in ISO UniProtKB:P12023 (MGI:3714552|PMID:17573534) RGD PMID:17573534 MGI:3714552 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in ISO
IEA
(PMID:24305806), (PMID:27853422)
GO_REF:0000107
RGD
Ensembl
PMID:24305806 PMID:27853422 GO_REF:0000107 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571
JBrowse link
G Rtn1 reticulon 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:15286784)
UniProt
RGD
PMID:15286784 GO_REF:0000024 NCBI chr 6:90,763,212...90,983,436
Ensembl chr 6:90,763,216...90,983,436
JBrowse link
G Rtn2 reticulon 2 involved_in ISO
ISS
(PMID:15286784)
GO_REF:0000024
RGD
UniProt
PMID:15286784 GO_REF:0000024 NCBI chr 1:78,935,056...78,948,069
Ensembl chr 1:78,935,104...78,948,069
JBrowse link
G Rtn3 reticulon 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:15286784)
UniProt
RGD
PMID:15286784 GO_REF:0000024 NCBI chr 1:204,612,675...204,669,212
Ensembl chr 1:204,612,675...204,669,275
JBrowse link
G Rtn4 reticulon 4 involved_in ISO
IEA
ISS
(PMID:15286784)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:15286784 GO_REF:0000024 GO_REF:0000107 NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686
JBrowse link
G Sorl1 sortilin related receptor 1 involved_in ISO (PMID:16407538), (PMID:17855360), (PMID:21989385), (PMID:22621900), (PMID:24001769), (PMID:24523320)
(MGI:3801250|PMID:18362153), (MGI:3821635|PMID:19036982)
RGD PMID:16407538 PMID:17855360 PMID:18362153 PMID:19036982 PMID:21989385 More... MGI:3801250 MGI:3821635 NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513
JBrowse link
G Spon1 spondin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3607023|PMID:16227578)
Ensembl
RGD
PMID:16227578 GO_REF:0000107 MGI:3607023 NCBI chr 1:167,929,049...168,228,239
Ensembl chr 1:167,928,972...168,228,226
JBrowse link
negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bin1 bridging integrator 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:5811968|PMID:27179792)
(PMID:27179792)
Ensembl
RGD
PMID:27179792 GO_REF:0000107 MGI:5811968 NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263
JBrowse link
G Sorl1 sortilin related receptor 1 involved_in ISO (PMID:16407538), (PMID:17855360), (PMID:21989385)
(MGI:3801250|PMID:18362153)
RGD PMID:16407538 PMID:17855360 PMID:18362153 PMID:21989385 MGI:3801250 NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513
JBrowse link
G Tmed10 transmembrane p24 trafficking protein 10 acts_upstream_of_or_within ISO (MGI:3623864|PMID:16641999) RGD PMID:16641999 MGI:3623864 NCBI chr 6:104,991,843...105,026,705
Ensembl chr 6:104,991,838...105,026,753
JBrowse link
negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Picalm phosphatidylinositol binding clathrin assembly protein involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:5432454|PMID:22539346)
GO_REF:0000024
Ensembl
RGD
Alzheimers_University_of_Toronto
PMID:22539346 GO_REF:0000024 GO_REF:0000107 MGI:5432454 NCBI chr 1:144,056,415...144,138,045
Ensembl chr 1:144,056,721...144,137,557
JBrowse link
G Sorl1 sortilin related receptor 1 involved_in ISO (PMID:17855360), (PMID:21989385)
(MGI:3801250|PMID:18362153)
RGD PMID:17855360 PMID:18362153 PMID:21989385 MGI:3801250 NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513
JBrowse link
positive regulation of amyloid precursor protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO UniProtKB:P56818 (PMID:20704561), (PMID:22086926) RGD PMID:20704561 PMID:22086926 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
JBrowse link
G Ranbp9 RAN binding protein 9 acts_upstream_of IGI PMID:24592211 ARUK-UCL PMID:24592211 RGD:38501074 NCBI chr17:21,220,807...21,303,009
Ensembl chr17:21,220,618...21,303,004
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in ISO (PMID:24305806)
(MGI:6114922|PMID:24305806)
RGD PMID:24305806 MGI:6114922 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031
JBrowse link
G Spon1 spondin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3607023|PMID:16227578)
Ensembl
RGD
PMID:16227578 GO_REF:0000107 MGI:3607023 NCBI chr 1:167,929,049...168,228,239
Ensembl chr 1:167,928,972...168,228,226
JBrowse link
positive regulation of amyloid-beta formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of
involved_in
ISO
IEA
IMP
(PMID:22086926)
GO_REF:0000107
RGD
Ensembl
PMID:22086926 PMID:22086926 GO_REF:0000107, RGD:14697726 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (PMID:17293612) RGD PMID:17293612 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:24154541), (PMID:24259049) RGD PMID:24154541 PMID:24259049 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Casp3 caspase 3 involved_in IDA
ISO
PMID:17553422
(PMID:17553422)
RGD PMID:17553422 PMID:17553422 RGD:13825190 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P05067 (MGI:4437154|PMID:20164328)
Ensembl
RGD
PMID:20164328 GO_REF:0000107 MGI:4437154 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240
JBrowse link
G Clu clusterin involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:2384259|PMID:12145324)
GO_REF:0000024
Ensembl
RGD
Alzheimers_University_of_Toronto
PMID:12145324 GO_REF:0000024 GO_REF:0000107 MGI:2384259 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Csnk1e casein kinase 1, epsilon IDA RGD PMID:17360493 RGD:10395238 NCBI chr 7:110,983,322...111,006,926
Ensembl chr 7:110,983,318...111,006,794
JBrowse link
G Efna1 ephrin A1 involved_in ISO (PMID:24217950) RGD PMID:24217950 NCBI chr 2:174,681,676...174,690,306
Ensembl chr 2:174,681,682...174,690,866
JBrowse link
G Epha4 Eph receptor A4 involved_in ISO UniProtKB:P20827 (PMID:24217950) RGD PMID:24217950 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139
JBrowse link
G Gsap gamma-secretase activating protein involved_in IBA
ISO
PMID:21873635
(MGI:4830390|PMID:20811458)
(PMID:20811458)
RGD PMID:20811458 PMID:21873635 MGI:4830390, RGD:13792537 NCBI chr 4:13,813,046...13,907,875
Ensembl chr 4:13,813,046...13,907,814
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO UniProtKB:P49841 (PMID:12761548) RGD PMID:12761548 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
JBrowse link
G Ifng interferon gamma involved_in ISO UniProtKB:P05067|UniProtKB:P10636|UniProtKB:P49768 (PMID:19808651)
UniProtKB:P05067|UniProtKB:P15261 (MGI:3697769|PMID:17255335)
RGD PMID:17255335 PMID:19808651 MGI:3697769 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ifngr1 interferon gamma receptor 1 involved_in ISO UniProtKB:P01579|UniProtKB:P05067 (MGI:3697769|PMID:17255335) RGD PMID:17255335 MGI:3697769 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785
JBrowse link
G Lrrtm3 leucine rich repeat transmembrane neuronal 3 acts_upstream_of_or_within ISO (MGI:3695648|PMID:17098871)
(PMID:17098871)
RGD PMID:17098871 MGI:3695648 NCBI chr20:24,515,627...24,689,669
Ensembl chr20:24,515,627...24,689,669
JBrowse link
G Mir206 microRNA 206 involved_in ISO (PMID:27277332) RGD PMID:27277332 NCBI chr 9:23,094,249...23,094,332
Ensembl chr 9:23,094,249...23,094,332
JBrowse link
G Mir346 microRNA 346 acts_upstream_of ISO (PMID:30470799) RGD PMID:30470799 NCBI chr16:10,218,118...10,218,215
Ensembl chr16:10,218,118...10,218,215
JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein involved_in ISO
ISS
IEA
(PMID:24577224)
(MGI:5432454|PMID:22539346), (MGI:5560380|PMID:24577224)
GO_REF:0000024
GO_REF:0000107
RGD
Alzheimers_University_of_Toronto
Ensembl
PMID:22539346 PMID:24577224 GO_REF:0000024 GO_REF:0000107 MGI:5432454 MGI:5560380 NCBI chr 1:144,056,415...144,138,045
Ensembl chr 1:144,056,721...144,137,557
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit acts_upstream_of ISO (MGI:6414694|PMID:21329555) RGD PMID:21329555 MGI:6414694 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in ISO
IEA
(PMID:24305806)
GO_REF:0000107
(MGI:6114922|PMID:24305806)
RGD
Ensembl
PMID:24305806 GO_REF:0000107 MGI:6114922 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031
JBrowse link
G Slc2a13 solute carrier family 2 member 13 involved_in ISO UniProtKB:P05067-4 (PMID:26094765) RGD PMID:26094765 NCBI chr 7:122,399,329...122,726,605
Ensembl chr 7:122,399,330...122,726,605
JBrowse link
G Sp1 Sp1 transcription factor acts_upstream_of ISO (PMID:14701757) RGD PMID:14701757 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
JBrowse link
G Tnf tumor necrosis factor involved_in ISO (MGI:3697769|PMID:17255335) RGD PMID:17255335 MGI:3697769 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor involved_in ISO UniProtKB:P05067:PRO_0000000093 (PMID:22406537) RGD PMID:22406537 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G App amyloid beta precursor protein involved_in ISO UniProtKB:Q15109 (PMID:22406537) RGD PMID:22406537 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Efna1 ephrin A1 involved_in ISO UniProtKB:P54764 (PMID:24217950) RGD PMID:24217950 NCBI chr 2:174,681,676...174,690,306
Ensembl chr 2:174,681,682...174,690,866
JBrowse link
G Efna3 ephrin A3 involved_in ISO UniProtKB:P54764 (PMID:24217950) RGD PMID:24217950 NCBI chr 2:174,729,192...174,738,111
Ensembl chr 2:174,729,764...174,738,736
JBrowse link
G Epha4 Eph receptor A4 involved_in ISO UniProtKB:P20827|UniProtKB:P52797 (PMID:24217950) RGD PMID:24217950 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:24217950) RGD PMID:24217950 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5432454|PMID:22539346)
GO_REF:0000107
Alzheimers_University_of_Toronto
RGD
Ensembl
PMID:22539346 GO_REF:0000024 GO_REF:0000107 MGI:5432454 NCBI chr 1:144,056,415...144,138,045
Ensembl chr 1:144,056,721...144,137,557
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in ISO
IEA
(PMID:24305806)
GO_REF:0000107
(MGI:6114922|PMID:24305806)
RGD
Ensembl
PMID:24305806 GO_REF:0000107 MGI:6114922 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031
JBrowse link
regulation of amyloid-beta formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Olfm1 olfactomedin 1 acts_upstream_of_or_within ISO (MGI:5444053|PMID:22992957) RGD PMID:22992957 MGI:5444053 NCBI chr 3:11,520,522...11,558,240
Ensembl chr 3:11,520,729...11,558,239
JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein NOT|involved_in ISO UniProtKB:P05067:PRO_0000000092 (MGI:5637941|PMID:26005850) RGD PMID:26005850 MGI:5637941 NCBI chr 1:144,056,415...144,138,045
Ensembl chr 1:144,056,721...144,137,557
JBrowse link
G Tmed10 transmembrane p24 trafficking protein 10 involved_in ISO
ISS
(PMID:16641999)
GO_REF:0000024
RGD
UniProt
PMID:16641999 GO_REF:0000024 NCBI chr 6:104,991,843...105,026,705
Ensembl chr 6:104,991,838...105,026,753
JBrowse link
regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Picalm phosphatidylinositol binding clathrin assembly protein involved_in ISO
ISS
(PMID:24577224)
GO_REF:0000024
RGD
Alzheimers_University_of_Toronto
PMID:24577224 GO_REF:0000024 NCBI chr 1:144,056,415...144,138,045
Ensembl chr 1:144,056,721...144,137,557
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20099
    metabolic process 12353
      regulation of metabolic process 7016
        regulation of macromolecule metabolic process 6493
          regulation of protein metabolic process 2805
            regulation of amyloid precursor protein catabolic process 58
              negative regulation of amyloid precursor protein catabolic process + 33
              positive regulation of amyloid precursor protein catabolic process + 28
              regulation of amyloid-beta formation + 50
              regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process + 11
              regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process + 2
Path 2
Term Annotations click to browse term
  biological_process 20099
    metabolic process 12353
      organic substance metabolic process 11873
        macromolecule metabolic process 10218
          protein metabolic process 6233
            amyloid precursor protein metabolic process 93
              amyloid precursor protein catabolic process 72
                regulation of amyloid precursor protein catabolic process 58
                  negative regulation of amyloid precursor protein catabolic process + 33
                  positive regulation of amyloid precursor protein catabolic process + 28
                  regulation of amyloid-beta formation + 50
                  regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process + 11
                  regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process + 2
paths to the root