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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of dendritic spine maintenance
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Accession:GO:1902951 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of dendritic spine maintenance.
Synonyms:exact_synonym: down regulation of dendritic spine maintenance;   downregulation of dendritic spine maintenance
 narrow_synonym: inhibition of dendritic spine maintenance


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negative regulation of dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E acts_upstream_of_or_within ISO (PMID:24328732) Alzheimers_University_of_Toronto PMID:24328732 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440 		JBrowse link
G CFL1 cofilin 1 ISO RGD PMID:23974706 RGD:11570553 NCBI chr18:51,404,649...51,408,240
Ensembl chr18:51,401,659...51,408,212 		JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:68,105,060...68,316,630
Ensembl chr12:68,075,184...68,316,541 		JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B involved_in ISO (MGI:5447900|PMID:22820466) ARUK-UCL PMID:22820466 MGI:5447900 NCBI chr27:32,470,889...32,883,606
Ensembl chr27:32,471,153...32,877,680 		JBrowse link
G PRNP prion protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:16,845,224...16,862,319
Ensembl chr24:16,846,207...16,859,815 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17878
    negative regulation of biological process 5711
      negative regulation of cellular process 5355
        negative regulation of cellular component organization 841
          negative regulation of cell projection organization 238
            negative regulation of dendritic spine maintenance 5
Path 2
Term Annotations click to browse term
  biological_process 17878
    cellular process 16920
      cellular component organization or biogenesis 6943
        cellular component organization 6704
          cell projection organization 1865
            plasma membrane bounded cell projection organization 1838
              neuron projection organization 118
                dendritic spine organization 106
                  dendritic spine maintenance 26
                    regulation of dendritic spine maintenance 15
                      negative regulation of dendritic spine maintenance 5
paths to the root