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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of cell cycle G1/S phase transition
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Accession:GO:1902808 term browser browse the term
Definition:Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle.
Synonyms:exact_synonym: up regulation of cell cycle G1/S phase transition;   upregulation of cell cycle G1/S phase transition
 narrow_synonym: activation of cell cycle G1/S phase transition



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positive regulation of cell cycle G1/S phase transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc73 cell division cycle 73 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:15923622)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:15923622 GO_REF:0000024 GO_REF:0000107 NCBI chr13:55,357,226...55,449,690
Ensembl chr13:55,357,226...55,449,656
JBrowse link
G Crnn cornulin involved_in ISO
IBA
(PMID:30009832)
GO_REF:0000033
RGD
GO_Central
PMID:30009832 GO_REF:0000033 NCBI chr 2:178,733,329...178,736,404
Ensembl chr 2:178,731,796...178,736,216
JBrowse link
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:7753556 RGD:151665769 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in ISO (PMID:18713946) RGD PMID:18713946 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G Fam83b family with sequence similarity 83, member B involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 8:77,287,351...77,363,795
Ensembl chr 8:77,287,351...77,363,795
JBrowse link
G Fam83d family with sequence similarity 83, member D involved_in ISO
IBA
(PMID:25646692)
GO_REF:0000033
RGD
GO_Central
PMID:25646692 GO_REF:0000033 NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192
JBrowse link
G Fam83e family with sequence similarity 83, member E involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 1:96,191,581...96,201,182
Ensembl chr 1:96,191,742...96,201,192
JBrowse link
G Fam83f family with sequence similarity 83, member F involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 7:112,211,164...112,240,454
Ensembl chr 7:112,211,164...112,240,452
JBrowse link
G Fam83g family with sequence similarity 83, member G involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr10:46,363,029...46,388,030
Ensembl chr10:46,363,051...46,388,019
JBrowse link
G Fam83h family with sequence similarity 83, member H involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 7:107,716,431...107,724,619
Ensembl chr 7:107,716,431...107,728,672
JBrowse link
G Gli1 GLI family zinc finger 1 involved_in ISO (PMID:28583401) RGD PMID:28583401 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251
JBrowse link
G Paf1 PAF1 homolog, Paf1/RNA polymerase II complex component involved_in ISO
ISS
(PMID:15923622)
GO_REF:0000024
RGD
UniProt
PMID:15923622 GO_REF:0000024 NCBI chr 1:83,683,654...83,689,233
Ensembl chr 1:83,668,813...83,689,237
JBrowse link
G Pagr1 Paxip1-associated glutamate-rich protein 1 involved_in ISO
IBA
(PMID:19039327)
GO_REF:0000033
RGD
GO_Central
PMID:19039327 GO_REF:0000033 NCBI chr 1:181,622,698...181,625,024 JBrowse link
G Phb2 prohibitin 2 involved_in ISO
IEA
(PMID:23548868)
GO_REF:0000107
RGD
Ensembl
PMID:23548868 GO_REF:0000107 NCBI chr 4:157,517,662...157,522,268
Ensembl chr 4:157,517,577...157,522,272
JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in IDA PMID:31549850 ARUK-UCL PMID:31549850 RGD:126781738 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930
JBrowse link
G Prrt2 proline-rich transmembrane protein 2 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 1:181,625,243...181,628,833
Ensembl chr 1:181,604,545...181,628,850
JBrowse link
G Stxbp4 syntaxin binding protein 4 involved_in ISO (PMID:19451233) RGD PMID:19451233 NCBI chr10:75,301,868...75,458,741
Ensembl chr10:75,305,463...75,458,663
JBrowse link
G Tbx1 T-box transcription factor 1 IMP RGD PMID:31982878 RGD:155882591 NCBI chr11:82,409,275...82,419,058
Ensembl chr11:82,409,275...82,418,380
JBrowse link
G Tbx2 T-box transcription factor 2 involved_in ISO (MGI:6810282|PMID:26486273) RGD PMID:26486273 MGI:6810282 NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529
JBrowse link
G Tp63 tumor protein p63 involved_in ISO (PMID:19451233) RGD PMID:19451233 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
JBrowse link
positive regulation of G1/S transition of mitotic cell cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 involved_in ISO
IEA
(PMID:18483258)
GO_REF:0000107
RGD
Ensembl
PMID:18483258 GO_REF:0000107 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 involved_in IEA
ISO
GO_REF:0000107
RNAcentral:URS00003A19A3_9606 (PMID:28890348)
Ensembl
RGD
PMID:28890348 GO_REF:0000107 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
JBrowse link
G Aif1 allograft inflammatory factor 1 involved_in ISO
ISS
(PMID:11557666), (PMID:15117732), (PMID:19745784)
GO_REF:0000024
RGD
UniProt
PMID:11557666 PMID:15117732 PMID:19745784 GO_REF:0000024 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in ISO
IEA
(PMID:18483258)
GO_REF:0000107
RGD
Ensembl
PMID:18483258 GO_REF:0000107 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Ankrd17 ankyrin repeat domain 17 involved_in ISO (PMID:19150984) RGD PMID:19150984 NCBI chr14:17,723,239...17,861,841
Ensembl chr14:17,721,932...17,862,617
JBrowse link
G Anp32b acidic nuclear phosphoprotein 32 family member B IMP RGD PMID:11162633 RGD:633716 NCBI chr 5:60,743,077...60,765,726
Ensembl chr 5:60,743,443...60,765,717
JBrowse link
G Anxa1 annexin A1 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:2449710 (MGI:2661244|PMID:12553880)
GO_REF:0000107
GO_REF:0000118
RGD
Ensembl
TreeGrafter
PMID:12553880 GO_REF:0000107 GO_REF:0000118 MGI:2661244 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 IMP RGD PMID:12730053 RGD:2315680 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
JBrowse link
G Ccnd1 cyclin D1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 involved_in ISO
IBA
IEA
(PMID:24130168)
GO_REF:0000033
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:24130168 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccnd3 cyclin D3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Ccne1 cyclin E1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Ccne2 cyclin E2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Cenpj centromere protein J involved_in ISO (PMID:22020124) RGD PMID:22020124 NCBI chr15:30,627,206...30,690,384
Ensembl chr15:30,627,224...30,686,791
JBrowse link
G Cpsf3 cleavage and polyadenylation specific factor 3 involved_in ISO (PMID:30507380) RGD PMID:30507380 NCBI chr 6:40,836,121...40,864,129
Ensembl chr 6:40,836,097...40,864,128
JBrowse link
G Crebbp CREB binding protein IMP RGD PMID:18496732 RGD:2316124 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
JBrowse link
G Cul4a cullin 4A acts_upstream_of_or_within ISO (MGI:3820325|PMID:19056892) RGD PMID:19056892 MGI:3820325 NCBI chr16:76,385,298...76,422,316
Ensembl chr16:76,384,546...76,422,330
JBrowse link
G Cul4b cullin 4B acts_upstream_of_or_within ISO (MGI:3820325|PMID:19056892) RGD PMID:19056892 MGI:3820325 NCBI chr  X:117,287,481...117,326,688
Ensembl chr  X:117,287,484...117,326,688
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IDA RGD PMID:14742689 RGD:2306669 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 IMP RGD PMID:32412792 RGD:150429761 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:20837705) RGD PMID:20837705 NCBI chr  X:9,479,532...9,493,169
Ensembl chr  X:9,479,532...9,493,168
JBrowse link
G Egfr epidermal growth factor receptor involved_in ISO (PMID:18483258) RGD PMID:18483258 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma 1 involved_in ISO (PMID:18426977) RGD PMID:18426977 NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941
JBrowse link
G Fgf10 fibroblast growth factor 10 involved_in ISO (PMID:17188682) RGD PMID:17188682 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866
JBrowse link
G Hyal1 hyaluronidase 1 involved_in ISO
IEA
ISS
(PMID:21829529)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:21829529 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:108,250,668...108,254,519
Ensembl chr 8:108,250,667...108,260,210
JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 IDA RGD PMID:18230363 RGD:7242757 NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697
JBrowse link
G Kmt2e lysine methyltransferase 2E involved_in ISO (PMID:23629655) RGD PMID:23629655 NCBI chr 4:11,658,218...11,727,373
Ensembl chr 4:11,658,979...11,727,373
JBrowse link
G Larp7 La ribonucleoprotein 7, transcriptional regulator acts_upstream_of_or_within ISO (MGI:5461251|PMID:23154982) RGD PMID:23154982 MGI:5461251 NCBI chr 2:215,997,641...216,012,833
Ensembl chr 2:215,997,649...216,012,865
JBrowse link
G Lsm10 LSM10, U7 small nuclear RNA associated involved_in ISO (PMID:16914750) RGD PMID:16914750 NCBI chr 5:138,365,983...138,375,856
Ensembl chr 5:138,373,119...138,377,505
JBrowse link
G Lsm11 LSM11, U7 small nuclear RNA associated involved_in ISO (PMID:16914750) RGD PMID:16914750 NCBI chr10:30,367,841...30,385,956
Ensembl chr10:30,370,727...30,385,944
JBrowse link
G Mblac1 metallo-beta-lactamase domain containing 1 involved_in ISO
ISS
(PMID:30507380)
GO_REF:0000024
RGD
UniProt
PMID:30507380 GO_REF:0000024 NCBI chr12:17,071,465...17,072,736
Ensembl chr12:17,071,465...17,072,735
JBrowse link
G Mepce methylphosphate capping enzyme acts_upstream_of_or_within ISO (MGI:5461251|PMID:23154982) RGD PMID:23154982 MGI:5461251 NCBI chr12:18,911,796...18,916,515
Ensembl chr12:18,911,796...18,916,514
JBrowse link
G Mir214 microRNA 214 involved_in ISO (PMID:27144530) RGD PMID:27144530 NCBI chr13:74,588,374...74,588,481
Ensembl chr13:74,588,372...74,588,481
JBrowse link
G Mir221 microRNA 221 involved_in ISO (PMID:18413744) RGD PMID:18413744 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573
JBrowse link
G Mir222 microRNA 222 involved_in ISO (PMID:18413744) RGD PMID:18413744 NCBI chr  X:3,428,904...3,429,006
Ensembl chr  X:3,428,904...3,429,006
JBrowse link
G Mir295-1 microRNA 295-1 involved_in ISO (PMID:20190813) RGD PMID:20190813 NCBI chr 1:65,962,566...65,962,646
Ensembl chr 1:65,962,566...65,962,646
JBrowse link
G Mir29a microRNA 29a involved_in ISO (PMID:23541945) RGD PMID:23541945 NCBI chr 4:59,650,608...59,650,695 JBrowse link
G Plcb1 phospholipase C beta 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:4942262|PMID:10913438)
GO_REF:0000107
BHF-UCL
RGD
Ensembl
PMID:10913438 GO_REF:0000024 GO_REF:0000107 MGI:4942262 NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869
JBrowse link
G Plrg1 pleiotropic regulator 1 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:3848230 (MGI:3847829|PMID:19307306)
GO_REF:0000107
RGD
Ensembl
PMID:19307306 GO_REF:0000107 MGI:3847829 NCBI chr 2:168,408,139...168,424,470
Ensembl chr 2:168,408,124...168,424,522
JBrowse link
G Rdx radixin involved_in ISO
IMP
(MGI:5645204|PMID:21047789) RGD PMID:21047789 PMID:21047789 MGI:5645204, RGD:10054076 NCBI chr 8:52,379,494...52,437,673
Ensembl chr 8:52,379,494...52,437,678
JBrowse link
G Rgcc regulator of cell cycle involved_in ISO (PMID:19162005) RGD PMID:19162005 NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141
JBrowse link
G Rpl17 ribosomal protein L17 IMP RGD PMID:23065385 RGD:11035308 NCBI chr18:68,581,141...68,584,253
Ensembl chr18:68,581,098...68,584,253
JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 involved_in ISO (PMID:18426977) RGD PMID:18426977 NCBI chr10:104,878,487...105,176,986
Ensembl chr10:104,878,487...105,176,983
JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 involved_in ISO (PMID:24253041) RGD PMID:24253041 NCBI chr 1:156,823,960...156,848,262
Ensembl chr 1:156,823,960...156,848,261
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 involved_in ISO (PMID:24253041) RGD PMID:24253041 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
JBrowse link
G Sass6 SAS-6 centriolar assembly protein involved_in ISO (PMID:22020124) RGD PMID:22020124 NCBI chr 2:204,546,660...204,578,930
Ensembl chr 2:204,546,660...204,578,927
JBrowse link
G Stil STIL, centriolar assembly protein involved_in ISO (PMID:22020124) RGD PMID:22020124 NCBI chr 5:128,520,837...128,573,732
Ensembl chr 5:128,520,953...128,573,730
JBrowse link
G Stox1 storkhead box 1 involved_in ISO (PMID:22253775) RGD PMID:22253775 NCBI chr20:30,598,284...30,666,371
Ensembl chr20:30,598,168...30,666,939
JBrowse link
G Tert telomerase reverse transcriptase IMP RGD PMID:24376652 RGD:11038675 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tfdp1 transcription factor Dp-1 involved_in ISO (PMID:17062573) RGD PMID:17062573 NCBI chr16:76,162,040...76,200,871
Ensembl chr16:76,162,043...76,200,817
JBrowse link
G Ube2e2 ubiquitin-conjugating enzyme E2E 2 acts_upstream_of_or_within ISO UniProtKB:P38936 (PMID:21628527) RGD PMID:21628527 NCBI chr15:6,980,241...7,257,912
Ensembl chr15:6,980,474...7,257,532
JBrowse link
traversing start control point of mitotic cell cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mdm2 MDM2 proto-oncogene acts_upstream_of_or_within ISO (MGI:2661697|PMID:10906133) RGD PMID:10906133 MGI:2661697 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mtbp MDM2 binding protein acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:2661697|PMID:10906133)
GO_REF:0000033
RGD
GO_Central
PMID:10906133 GO_REF:0000033 MGI:2661697 NCBI chr 7:86,973,215...87,055,775
Ensembl chr 7:86,973,069...87,050,827
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    cellular process 18766
      cell cycle process 1344
        cell cycle phase transition 544
          cell cycle G1/S phase transition 247
            positive regulation of cell cycle G1/S phase transition 73
              positive regulation of G1/S transition of mitotic cell cycle + 53
Path 2
Term Annotations click to browse term
  biological_process 20292
    biological regulation 13616
      regulation of biological process 13210
        regulation of cellular process 12671
          regulation of cell cycle 1091
            regulation of cell cycle process 769
              positive regulation of cell cycle process 296
                positive regulation of cell cycle phase transition 129
                  positive regulation of cell cycle G1/S phase transition 73
                    positive regulation of G1/S transition of mitotic cell cycle + 53
paths to the root