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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of cell cycle G1/S phase transition
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Accession:GO:1902806 term browser browse the term
Definition:Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle.


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regulation of cell cycle G1/S phase transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 involved_in ISO (PMID:24448801) RGD PMID:24448801 NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A involved_in ISO (PMID:23213251) RGD PMID:23213251 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B involved_in ISO (PMID:8033212) RGD PMID:8033212 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cirbp cold inducible RNA binding protein acts_upstream_of_or_within ISO (MGI:87836|PMID:9151692) RGD PMID:9151692 MGI:87836 NCBI chr 7:9,533,857...9,538,899 JBrowse link
G Mn1 MN1 proto-oncogene, transcriptional regulator involved_in ISO (PMID:15890672) RGD PMID:15890672 NCBI chr12:45,184,060...45,220,102
Ensembl chr12:45,183,085...45,221,651
JBrowse link
G Plpp2 phospholipid phosphatase 2 involved_in IMP PMID:16467304 UniProt PMID:16467304 RGD:15090837 NCBI chr 7:10,175,918...10,184,032
Ensembl chr 7:10,175,948...10,184,071
JBrowse link
G Tcim transcriptional and immune response regulator involved_in ISO (PMID:18959821) RGD PMID:18959821 NCBI chr16:67,595,762...67,597,055
Ensembl chr16:67,593,410...67,597,581
JBrowse link
G Trim39 tripartite motif-containing 39 involved_in ISS
ISO
GO_REF:0000024
(PMID:23213251)
UniProt
RGD
PMID:23213251 GO_REF:0000024 NCBI chr20:2,003,320...2,017,175
Ensembl chr20:1,983,533...2,020,117
JBrowse link
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp2 caspase 2 involved_in ISO (PMID:21726810) RGD PMID:21726810 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A involved_in ISO (PMID:15149599) RGD PMID:15149599 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain involved_in IBA
ISO
PMID:21873635
(PMID:21726810)
RGD PMID:21726810 PMID:21873635 RGD:13792537 NCBI chr 7:29,940,240...29,952,907
Ensembl chr 7:29,798,586...29,952,907
JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in ISO (PMID:21726810) RGD PMID:21726810 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Muc1 mucin 1, cell surface associated involved_in ISO (PMID:15710329) RGD PMID:15710329 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Pidd1 p53-induced death domain protein 1 involved_in ISO (PMID:21726810) RGD PMID:21726810 NCBI chr 1:196,536,815...196,542,808
Ensembl chr 1:196,536,834...196,542,699
JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (MGI:3580934|PMID:15626733) RGD PMID:15626733 MGI:3580934 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma involved_in ISO (PMID:17245430) RGD PMID:17245430 NCBI chr 6:129,461,689...129,598,344
Ensembl chr 6:129,461,648...129,598,346
JBrowse link
G Prap1 proline-rich acidic protein 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:23235459)
UniProt
RGD
PMID:23235459 GO_REF:0000024 NCBI chr 1:194,883,078...194,886,874
Ensembl chr 1:194,883,078...194,886,872
JBrowse link
G Rbm38 RNA binding motif protein 38 involved_in ISO (PMID:17050675) RGD PMID:17050675 NCBI chr 3:161,801,550...161,814,381
Ensembl chr 3:161,801,577...161,814,381
JBrowse link
G Rpl26 ribosomal protein L26 involved_in ISO (PMID:16213212)
(MGI:5882892|PMID:16213212)
RGD PMID:16213212 MGI:5882892 NCBI chr10:53,610,836...53,613,966
Ensembl chr10:53,610,421...53,613,966
JBrowse link
G Sox4 SRY-box transcription factor 4 involved_in ISO (PMID:19234109) RGD PMID:19234109 NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665
JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within
ISO (PMID:16213212)
MGI:108027 (MGI:3589512|PMID:16107883)
RGD PMID:16107883 PMID:16213212 MGI:3589512 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
mitotic G1 DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnd1 cyclin D1 involved_in ISS
ISO
GO_REF:0000024
(PMID:19412162)
UniProt
RGD
PMID:19412162 GO_REF:0000024 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Dgkz diacylglycerol kinase zeta involved_in ISO UniProtKB:P06400 (PMID:16286473) RGD PMID:16286473 NCBI chr 3:77,904,149...77,946,114
Ensembl chr 3:77,904,150...77,946,099
JBrowse link
G Fbxo31 F-box protein 31 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:19412162)
GO_REF:0000002
UniProt
RGD
InterPro
PMID:19412162 GO_REF:0000002 GO_REF:0000024 NCBI chr19:49,624,818...49,656,083
Ensembl chr19:49,627,686...49,656,010
JBrowse link
G Gigyf2 GRB10 interacting GYF protein 2 acts_upstream_of_or_within ISO MGI:4126459 (MGI:4366664|PMID:19744960) RGD PMID:19744960 MGI:4366664 NCBI chr 9:88,001,212...88,127,040
Ensembl chr 9:88,001,301...88,125,715
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:21731742) RGD PMID:21731742 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
JBrowse link
G Rfwd3 ring finger and WD repeat domain 3 involved_in ISO (PMID:20173098) RGD PMID:20173098 NCBI chr19:39,235,883...39,268,536
Ensembl chr19:39,236,787...39,268,479
JBrowse link
G Rpa2 replication protein A2 involved_in ISO (PMID:21731742) RGD PMID:21731742 NCBI chr 5:144,976,789...144,989,445
Ensembl chr 5:144,976,748...144,987,350
JBrowse link
G Rps27l ribosomal protein S27-like involved_in ISO (PMID:18056458) RGD PMID:18056458 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418
JBrowse link
G Sde2 SDE2 telomere maintenance homolog involved_in IEA
ISO
GO_REF:0000107
(PMID:27906959)
Ensembl
RGD
PMID:27906959 GO_REF:0000107 NCBI chr13:92,578,843...92,595,142
Ensembl chr13:92,578,874...92,595,140
JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within
ISO (PMID:7958916)
(MGI:3589512|PMID:16107883)
RGD PMID:7958916 PMID:16107883 MGI:3589512 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO MGI:3052754 (MGI:3818783|PMID:18045533), (MGI:5562498|PMID:23993650) RGD PMID:18045533 PMID:23993650 MGI:3818783 MGI:5562498 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796
JBrowse link
G Wac WW domain containing adaptor with coiled-coil involved_in ISO (PMID:21329877) RGD PMID:21329877 NCBI chr17:55,922,686...55,984,286
Ensembl chr17:55,923,123...55,982,301
JBrowse link
mitotic G1/S transition checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plk3 polo-like kinase 3 involved_in IBA
ISO
ISS
PMID:21873635
(MGI:5142362|PMID:21376736)
GO_REF:0000024
RGD
UniProt
PMID:21376736 PMID:21873635 GO_REF:0000024 MGI:5142362, RGD:13792537 NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317
JBrowse link
G Plk5 polo-like kinase 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:9,346,777...9,367,923
Ensembl chr 7:9,346,777...9,355,196
JBrowse link
negative regulation of cell cycle G1/S phase transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apbb1 amyloid beta precursor protein binding family B member 1 involved_in IDA PMID:12089154 UniProt PMID:12089154 RGD:127285400 NCBI chr 1:159,896,889...159,920,505
Ensembl chr 1:159,896,880...159,920,627
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B IMP RGD PMID:26526028 RGD:11252201 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
JBrowse link
G Cdkn2d cyclin dependent kinase inhibitor 2D acts_upstream_of_or_within ISO (MGI:72259|PMID:7739547) RGD PMID:7739547 MGI:72259 NCBI chr 8:19,831,874...19,834,640
Ensembl chr 8:19,831,866...19,834,674
JBrowse link
G LOC290595 hypothetical gene supported by AF152002 involved_in ISO (PMID:25351403) RGD PMID:25351403 NCBI chr16:12,868,270...12,875,876
Ensembl chr16:12,868,270...12,875,876
JBrowse link
G Men1 menin 1 IMP RGD PMID:15054094 RGD:1304318 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871
JBrowse link
G Mettl13 methyltransferase 13, eEF1A lysine and N-terminal methyltransferase involved_in ISO (PMID:26763933) RGD PMID:26763933 NCBI chr13:74,886,151...74,899,937
Ensembl chr13:74,886,155...74,899,870
JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (PMID:10918569) RGD PMID:10918569 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Susd2 sushi domain containing 2 involved_in ISO (PMID:25351403) RGD PMID:25351403 NCBI chr20:13,017,468...13,024,903
Ensembl chr20:13,017,477...13,024,903
JBrowse link
negative regulation of G1/S transition of mitotic cell cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway involved_in ISO
IEA
(PMID:10656683)
GO_REF:0000107
RGD
Ensembl
PMID:10656683 GO_REF:0000107 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:2679141|PMID:12855558), (MGI:3032471|PMID:14660795)
Ensembl
RGD
PMID:12855558 PMID:14660795 GO_REF:0000107 MGI:2679141 MGI:3032471 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Brd7 bromodomain containing 7 involved_in ISO (PMID:16265664) RGD PMID:16265664 NCBI chr19:18,708,792...18,737,500
Ensembl chr19:18,709,022...18,737,494
JBrowse link
G Btn2a2 butyrophilin, subfamily 2, member A2 acts_upstream_of_or_within ISO (MGI:5520006|PMID:23589618) RGD PMID:23589618 MGI:5520006 NCBI chr17:41,620,807...41,632,621
Ensembl chr17:41,620,839...41,632,618
JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 IDA RGD PMID:28587927 RGD:13515054 NCBI chr 3:36,906,771...37,169,191
Ensembl chr 3:36,910,427...37,168,944
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 involved_in ISO (PMID:25466836) RGD PMID:25466836 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cdc73 cell division cycle 73 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:16989776)
UniProt
Ensembl
RGD
PMID:16989776 GO_REF:0000024 GO_REF:0000107 NCBI chr13:55,357,226...55,449,690
Ensembl chr13:55,357,226...55,449,656
JBrowse link
G Cdk2ap2 cyclin-dependent kinase 2 associated protein 2 involved_in ISO (PMID:23781148) RGD PMID:23781148 NCBI chr 1:201,391,056...201,393,137
Ensembl chr 1:201,391,466...201,393,137
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A acts_upstream_of_or_within ISO UniProtKB:Q96LR5 (PMID:21628527) RGD PMID:21628527 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5461251|PMID:23154982)
Ensembl
RGD
PMID:23154982 GO_REF:0000107 MGI:5461251 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
JBrowse link
G Ctdsp1 CTD small phosphatase 1 acts_upstream_of_or_within ISO (MGI:5494382|PMID:22210897) RGD PMID:22210897 MGI:5494382 NCBI chr 9:75,973,694...75,979,298
Ensembl chr 9:75,973,962...75,979,297
JBrowse link
G Ctdsp2 CTD small phosphatase 2 acts_upstream_of_or_within ISO (MGI:5494382|PMID:22210897) RGD PMID:22210897 MGI:5494382 NCBI chr 7:62,805,400...62,825,306 JBrowse link
G Ctdspl CTD small phosphatase like acts_upstream_of_or_within ISO (MGI:5494382|PMID:22210897) RGD PMID:22210897 MGI:5494382 NCBI chr 8:118,642,729...118,767,238
Ensembl chr 8:118,642,672...118,767,117
JBrowse link
G Dact1 dishevelled-binding antagonist of beta-catenin 1 involved_in ISO (PMID:18936100) RGD PMID:18936100 NCBI chr 6:89,790,676...89,818,254
Ensembl chr 6:89,790,644...89,817,906
JBrowse link
G Dcun1d3 defective in cullin neddylation 1 domain containing 3 involved_in ISO
ISS
(PMID:18823379)
GO_REF:0000024
RGD
UniProt
PMID:18823379 GO_REF:0000024 NCBI chr 1:174,243,001...174,285,647
Ensembl chr 1:66,494,848...66,496,343
Ensembl chr 1:66,494,848...66,496,343
JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:10656683)
UniProt
Ensembl
RGD
PMID:10656683 GO_REF:0000024 GO_REF:0000107 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689
JBrowse link
G E2f7 E2F transcription factor 7 involved_in ISS
ISO
GO_REF:0000024
(MGI:5448509|PMID:22180533)
UniProt
RGD
PMID:22180533 GO_REF:0000024 MGI:5448509 NCBI chr 7:46,150,533...46,192,739
Ensembl chr 7:46,151,293...46,192,734
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit acts_upstream_of_or_within ISO MGI:2661097 (MGI:3846264|PMID:19303854) RGD PMID:19303854 MGI:3846264 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G Fam107a family with sequence similarity 107, member A involved_in ISO
IEA
ISS
(PMID:28604741)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:28604741 GO_REF:0000024 GO_REF:0000107 NCBI chr15:16,608,362...16,630,398
Ensembl chr15:16,607,205...16,630,396
JBrowse link
G Fbxo7 F-box protein 7 acts_upstream_of_or_within ISO (MGI:5317390|PMID:21652635) RGD PMID:21652635 MGI:5317390 NCBI chr 7:17,809,224...17,837,549
Ensembl chr 7:17,809,231...17,837,530
JBrowse link
G Fhl1 four and a half LIM domains 1 involved_in ISO (PMID:21702045) RGD PMID:21702045 NCBI chr  X:134,555,399...134,614,930
Ensembl chr  X:134,555,479...134,614,928
JBrowse link
G Gjc2 gap junction protein, gamma 2 IMP RGD PMID:28278052 RGD:13208599 NCBI chr10:43,962,642...43,971,358
Ensembl chr10:43,962,642...43,970,467
JBrowse link
G Gpnmb glycoprotein nmb involved_in ISO (PMID:19350579) RGD PMID:19350579 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
JBrowse link
G Haspin histone H3 associated protein kinase acts_upstream_of_or_within ISO (MGI:1338645|PMID:10358056) RGD PMID:10358056 MGI:1338645 NCBI chr10:57,747,731...57,750,532
Ensembl chr10:57,747,573...57,750,512
JBrowse link
G Jade1 jade family PHD finger 1 acts_upstream_of_or_within ISO (PMID:23001567) RGD PMID:23001567 NCBI chr 2:124,543,259...124,596,361
Ensembl chr 2:124,543,286...124,596,354
JBrowse link
G Kank2 KN motif and ankyrin repeat domains 2 involved_in IBA
ISO
PMID:21873635
(PMID:17476305)
RGD PMID:17476305 PMID:21873635 RGD:13792537 NCBI chr 8:20,311,676...20,341,107
Ensembl chr 8:20,311,676...20,340,900
JBrowse link
G Klf4 Kruppel like factor 4 involved_in ISO (PMID:23867820) RGD PMID:23867820 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
JBrowse link
G Mir26a microRNA 26a acts_upstream_of_or_within ISO (MGI:5494382|PMID:22210897) RGD PMID:22210897 MGI:5494382 NCBI chr 8:118,755,289...118,755,378
Ensembl chr 8:118,755,289...118,755,378
JBrowse link
G Mir26b microRNA 26b acts_upstream_of_or_within ISO (MGI:5494382|PMID:22210897) RGD PMID:22210897 MGI:5494382 NCBI chr 9:75,976,596...75,976,680
Ensembl chr 9:75,976,596...75,976,680
JBrowse link
G Myo16 myosin XVI involved_in IBA
IDA
PMID:21873635
PMID:17029291
GO_Central
BHF-UCL
PMID:21873635 PMID:17029291 RGD:13792537, RGD:8554212 NCBI chr16:78,884,405...79,364,445
Ensembl chr16:78,884,406...79,248,388
JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:16311606) RGD PMID:16311606 NCBI chr14:5,237,135...5,280,455
Ensembl chr14:5,237,135...5,280,825
JBrowse link
G Ppp2r3b protein phosphatase 2, regulatory subunit B'', beta acts_upstream_of_or_within ISO (MGI:1329724|PMID:9927208) RGD PMID:9927208 MGI:1329724 NCBI chr14:88,507...95,750
Ensembl chr14:89,176...95,750
JBrowse link
G Prmt2 protein arginine methyltransferase 2 involved_in ISO (MGI:3653799|PMID:16616919) RGD PMID:16616919 MGI:3653799 NCBI chr20:12,394,748...12,420,643
Ensembl chr20:12,394,798...12,420,643
JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (PMID:21241890) RGD PMID:21241890 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000107
MGI:1857339 (MGI:3664376|PMID:7958874)
PMID:21873635
Ensembl
RGD
PMID:7958874 PMID:21873635 GO_REF:0000107 MGI:3664376, RGD:13792537 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rbl1 RB transcriptional corepressor like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:145,806,160...145,869,434
Ensembl chr 3:145,807,095...145,869,330
JBrowse link
G Rbl2 RB transcriptional corepressor like 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:15,876,852...15,923,632
Ensembl chr19:15,876,853...15,923,572
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in ISO (MGI:6271967|PMID:30321469) RGD PMID:30321469 MGI:6271967 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Slfn13 schlafen family member 13 involved_in ISO (PMID:22927417) RGD PMID:22927417 NCBI chr10:67,909,105...67,955,912
Ensembl chr10:67,909,106...67,925,383
JBrowse link
G Zc3h12d zinc finger CCCH type containing 12D involved_in ISO (PMID:19531561) RGD PMID:19531561 NCBI chr 1:2,313,110...2,348,820
Ensembl chr 1:2,314,324...2,348,819
JBrowse link
G Zfp655 zinc finger protein 655 involved_in ISS
ISO
GO_REF:0000024
(PMID:15558030)
UniProt
RGD
PMID:15558030 GO_REF:0000024 NCBI chr12:9,349,985...9,375,449
Ensembl chr12:9,357,639...9,374,569
JBrowse link
negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nacc2 NACC family member 2 involved_in ISO
IEA
IBA
(PMID:22926524)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:22926524 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 3:8,879,952...8,946,660
Ensembl chr 3:8,883,065...8,946,660
JBrowse link
positive regulation of cell cycle G1/S phase transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc73 cell division cycle 73 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:15923622)
Ensembl
UniProt
RGD
PMID:15923622 GO_REF:0000024 GO_REF:0000107 NCBI chr13:55,357,226...55,449,690
Ensembl chr13:55,357,226...55,449,656
JBrowse link
G Crnn cornulin involved_in ISO
IBA
(PMID:30009832)
PMID:21873635
RGD PMID:30009832 PMID:21873635 RGD:13792537 NCBI chr 2:178,733,329...178,736,404
Ensembl chr 2:178,731,796...178,736,216
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in ISO (PMID:18713946) RGD PMID:18713946 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G Fam83d family with sequence similarity 83, member D involved_in IBA
ISO
PMID:21873635
(PMID:25646692)
RGD PMID:25646692 PMID:21873635 RGD:13792537 NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192
JBrowse link
G Gli1 GLI family zinc finger 1 involved_in ISO (PMID:28583401) RGD PMID:28583401 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251
JBrowse link
G Paf1 PAF1 homolog, Paf1/RNA polymerase II complex component involved_in ISO
ISS
(PMID:15923622)
GO_REF:0000024
RGD
UniProt
PMID:15923622 GO_REF:0000024 NCBI chr 1:83,683,654...83,689,233
Ensembl chr 1:83,668,813...83,689,237
JBrowse link
G Pagr1 Paxip1-associated glutamate-rich protein 1 involved_in IBA
ISO
PMID:21873635
(PMID:19039327)
RGD PMID:19039327 PMID:21873635 RGD:13792537 NCBI chr 1:181,622,708...181,624,996 JBrowse link
G Phb2 prohibitin 2 involved_in ISO (PMID:23548868) RGD PMID:23548868 NCBI chr 4:157,517,662...157,522,268
Ensembl chr 4:157,517,577...157,522,272
JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in IDA PMID:31549850 ARUK-UCL PMID:31549850 RGD:126781738 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930
JBrowse link
G Stxbp4 syntaxin binding protein 4 involved_in ISO (PMID:19451233) RGD PMID:19451233 NCBI chr10:75,301,868...75,458,741
Ensembl chr10:75,305,463...75,458,663
JBrowse link
G Tp63 tumor protein p63 involved_in ISO (PMID:19451233) RGD PMID:19451233 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
JBrowse link
positive regulation of G1/S transition of mitotic cell cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 involved_in ISO
IEA
(PMID:18483258)
GO_REF:0000107
RGD
Ensembl
PMID:18483258 GO_REF:0000107 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 involved_in IEA
ISO
GO_REF:0000107
RNAcentral:URS00003A19A3_9606 (PMID:28890348)
Ensembl
RGD
PMID:28890348 GO_REF:0000107 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
JBrowse link
G Aif1 allograft inflammatory factor 1 involved_in ISO
ISS
(PMID:11557666), (PMID:15117732), (PMID:19745784)
GO_REF:0000024
RGD
UniProt
PMID:11557666 PMID:15117732 PMID:19745784 GO_REF:0000024 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (PMID:18483258) RGD PMID:18483258 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Ankrd17 ankyrin repeat domain 17 involved_in ISO (PMID:19150984) RGD PMID:19150984 NCBI chr14:17,723,239...17,862,625
Ensembl chr14:17,721,932...17,862,617
JBrowse link
G Anp32b acidic nuclear phosphoprotein 32 family member B IMP RGD PMID:11162633 RGD:633716 NCBI chr 5:60,743,077...60,765,726
Ensembl chr 5:60,743,443...60,765,717
JBrowse link
G Anxa1 annexin A1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2449710 (MGI:2661244|PMID:12553880)
RGD PMID:12553880 PMID:21873635 MGI:2661244, RGD:13792537 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 IMP RGD PMID:12730053 RGD:2315680 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
JBrowse link
G Ccnd1 cyclin D1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 involved_in IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:24130168)
Ensembl
RGD
PMID:24130168 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccnd3 cyclin D3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Crebbp CREB binding protein IMP RGD PMID:18496732 RGD:2316124 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
JBrowse link
G Cul4a cullin 4A acts_upstream_of_or_within ISO (MGI:3820325|PMID:19056892) RGD PMID:19056892 MGI:3820325 NCBI chr16:76,385,298...76,422,316
Ensembl chr16:76,384,546...76,422,330
JBrowse link
G Cul4b cullin 4B acts_upstream_of_or_within ISO (MGI:3820325|PMID:19056892) RGD PMID:19056892 MGI:3820325 NCBI chr  X:117,287,481...117,326,688
Ensembl chr  X:117,287,484...117,326,688
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IDA RGD PMID:14742689 RGD:2306669 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:20837705) RGD PMID:20837705 NCBI chr  X:9,479,532...9,493,455
Ensembl chr  X:9,479,532...9,493,168
JBrowse link
G Egfr epidermal growth factor receptor involved_in ISO (PMID:18483258) RGD PMID:18483258 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma, 1 involved_in ISO (PMID:18426977) RGD PMID:18426977 NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941
JBrowse link
G Fgf10 fibroblast growth factor 10 involved_in ISO (PMID:17188682) RGD PMID:17188682 NCBI chr 2:50,801,897...50,875,428
Ensembl chr 2:50,800,992...50,876,866
JBrowse link
G Hyal1 hyaluronidase 1 involved_in ISO
IEA
ISS
(PMID:21829529)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:21829529 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:108,250,654...108,254,526
Ensembl chr 8:108,250,667...108,260,210
JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 IDA RGD PMID:18230363 RGD:7242757 NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697
JBrowse link
G Kmt2e lysine methyltransferase 2E involved_in ISO (PMID:23629655) RGD PMID:23629655 NCBI chr 4:11,657,811...11,727,373
Ensembl chr 4:11,658,979...11,727,373
JBrowse link
G Larp7 La ribonucleoprotein 7, transcriptional regulator acts_upstream_of_or_within ISO (MGI:5461251|PMID:23154982) RGD PMID:23154982 MGI:5461251 NCBI chr 2:215,997,641...216,012,833
Ensembl chr 2:215,997,649...216,012,865
JBrowse link
G Lsm10 LSM10, U7 small nuclear RNA associated involved_in ISO (PMID:16914750) RGD PMID:16914750 NCBI chr 5:138,365,983...138,375,856
Ensembl chr 5:138,373,119...138,377,505
JBrowse link
G Lsm11 LSM11, U7 small nuclear RNA associated involved_in ISO (PMID:16914750) RGD PMID:16914750 NCBI chr10:30,367,841...30,385,956
Ensembl chr10:30,370,727...30,385,944
JBrowse link
G Mepce methylphosphate capping enzyme acts_upstream_of_or_within ISO (MGI:5461251|PMID:23154982) RGD PMID:23154982 MGI:5461251 NCBI chr12:18,911,796...18,916,515
Ensembl chr12:18,911,796...18,916,514
JBrowse link
G Plcb1 phospholipase C beta 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:4942262|PMID:10913438)
GO_REF:0000107
BHF-UCL
RGD
Ensembl
PMID:10913438 GO_REF:0000024 GO_REF:0000107 MGI:4942262 NCBI chr 3:122,059,968...122,772,896
Ensembl chr 3:122,060,031...122,772,869
JBrowse link
G Plrg1 pleiotropic regulator 1 acts_upstream_of_or_within ISO MGI:3848230 (MGI:3847829|PMID:19307306) RGD PMID:19307306 MGI:3847829 NCBI chr 2:168,408,139...168,424,470
Ensembl chr 2:168,408,124...168,424,522
JBrowse link
G Rdx radixin involved_in ISO (MGI:5645204|PMID:21047789) RGD PMID:21047789 MGI:5645204 NCBI chr 8:52,379,494...52,437,673
Ensembl chr 8:52,379,494...52,437,678
JBrowse link
G Rgcc regulator of cell cycle involved_in ISO (PMID:19162005) RGD PMID:19162005 NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141
JBrowse link
G Rpl17 ribosomal protein L17 IMP RGD PMID:23065385 RGD:11035308 NCBI chr18:68,581,147...68,584,253
Ensembl chr18:68,581,098...68,584,253
JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 involved_in ISO (PMID:18426977) RGD PMID:18426977 NCBI chr10:104,878,487...105,176,986
Ensembl chr10:104,878,487...105,176,983
JBrowse link
G Tert telomerase reverse transcriptase IMP RGD PMID:24376652 RGD:11038675 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tfdp1 transcription factor Dp-1 involved_in ISO (PMID:17062573) RGD PMID:17062573 NCBI chr16:76,162,040...76,200,871
Ensembl chr16:76,162,043...76,200,817
JBrowse link
G Ube2e2 ubiquitin-conjugating enzyme E2E 2 acts_upstream_of_or_within ISO UniProtKB:P38936 (PMID:21628527) RGD PMID:21628527 NCBI chr15:6,980,195...7,257,912
Ensembl chr15:6,980,474...7,257,532
JBrowse link
regulation of G1/S transition of mitotic cell cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ak1 adenylate kinase 1 acts_upstream_of_or_within ISO (MGI:1928244|PMID:10557075) RGD PMID:10557075 MGI:1928244 NCBI chr 3:15,912,431...15,923,045 JBrowse link
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (PMID:15016378) RGD PMID:15016378 NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692
JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (PMID:15016378) RGD PMID:15016378 NCBI chr 7:20,135,248...20,184,757
Ensembl chr 7:20,135,375...20,184,754
JBrowse link
G Bid BH3 interacting domain death agonist acts_upstream_of_or_within ISO MGI:2158671 (MGI:3578502|PMID:15855651) RGD PMID:15855651 MGI:3578502 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Ccnd1 cyclin D1 acts_upstream_of_or_within ISO MGI:1351650 (MGI:5317249|PMID:21411630) RGD PMID:21411630 MGI:5317249 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G E2f1 E2F transcription factor 1 involved_in ISO (PMID:20224733) RGD PMID:20224733 NCBI chr 3:143,064,535...143,075,362 JBrowse link
G Ecd ecdysoneless cell cycle regulator acts_upstream_of_or_within ISO MGI:4414760 (MGI:4414625|PMID:19640839) RGD PMID:19640839 MGI:4414625 NCBI chr15:3,967,209...3,998,713
Ensembl chr15:3,967,382...3,998,706
JBrowse link
G Hacd1 3-hydroxyacyl-CoA dehydratase 1 acts_upstream_of_or_within ISO (MGI:5319048|PMID:22106411) RGD PMID:22106411 MGI:5319048 NCBI chr17:77,081,508...77,106,114
Ensembl chr17:77,083,740...77,106,073
JBrowse link
G Id2 inhibitor of DNA binding 2 involved_in ISO (PMID:16311606) RGD PMID:16311606 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Ino80 INO80 complex ATPase subunit involved_in ISO (PMID:20237820) RGD PMID:20237820 NCBI chr 3:106,368,455...106,465,716
Ensembl chr 3:106,368,455...106,467,911
JBrowse link
G Kif14 kinesin family member 14 involved_in ISO (PMID:24854087) RGD PMID:24854087 NCBI chr13:47,926,975...47,990,598
Ensembl chr13:47,927,044...47,989,164
JBrowse link
G Men1 menin 1 acts_upstream_of_or_within ISO MGI:2158697|MGI:3663673 (MGI:3639378|PMID:16740708) RGD PMID:16740708 MGI:3639378 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871
JBrowse link
G Pdpn podoplanin acts_upstream_of_or_within ISO MGI:2657021 (MGI:3703126|PMID:16869965) RGD PMID:16869965 MGI:3703126 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656
JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting involved_in ISO (PMID:16311606) RGD PMID:16311606 NCBI chr10:13,573,779...13,621,138
Ensembl chr10:13,573,021...13,621,128
JBrowse link
G Plk5 polo-like kinase 5 involved_in ISO (PMID:21245385)
(MGI:4946977|PMID:21245385), (MGI:5009782|PMID:20100802)
RGD PMID:20100802 PMID:21245385 MGI:4946977 MGI:5009782 NCBI chr 7:9,346,777...9,367,923
Ensembl chr 7:9,346,777...9,355,196
JBrowse link
G Psme1 proteasome activator subunit 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:29,069,012...29,071,888
Ensembl chr15:29,068,729...29,071,890
JBrowse link
G Psme1-ps1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha), pseudogene 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:50,174,233...50,175,012
Ensembl chr17:50,174,186...50,175,160
JBrowse link
G Psme2 proteasome activator subunit 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:29,078,495...29,082,794
Ensembl chr15:29,078,500...29,082,946
JBrowse link
G Psme3 proteasome activator subunit 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:86,257,672...86,265,458 JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 involved_in ISO
IEA
(PMID:19838216)
GO_REF:0000107
RGD
Ensembl
PMID:19838216 GO_REF:0000107 NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984
JBrowse link
G Senp2 SUMO specific peptidase 2 acts_upstream_of_or_within ISO MGI:3832730 (MGI:3831588|PMID:19090619) RGD PMID:19090619 MGI:3831588 NCBI chr11:78,981,429...79,018,274
Ensembl chr11:78,981,432...79,018,238
JBrowse link
G Tcf3 transcription factor 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:11509675)
UniProt
RGD
PMID:11509675 GO_REF:0000024 NCBI chr 7:9,280,571...9,302,315
Ensembl chr 7:9,280,571...9,302,314
JBrowse link
G Tjp3 tight junction protein 3 acts_upstream_of_or_within ISO MGI:88313 (MGI:5317249|PMID:21411630) RGD PMID:21411630 MGI:5317249 NCBI chr 7:8,427,650...8,446,279
Ensembl chr 7:8,432,811...8,446,279
JBrowse link
G Tm4sf5 transmembrane 4 L six family member 5 involved_in ISO (PMID:20399237) RGD PMID:20399237 NCBI chr10:55,219,384...55,225,742
Ensembl chr10:55,219,384...55,225,742
JBrowse link
traversing start control point of mitotic cell cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mdm2 MDM2 proto-oncogene acts_upstream_of_or_within ISO (MGI:2661697|PMID:10906133) RGD PMID:10906133 MGI:2661697 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mtbp MDM2 binding protein involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:2661697|PMID:10906133)
RGD PMID:10906133 PMID:21873635 MGI:2661697, RGD:13792537 NCBI chr 7:86,973,069...87,055,775
Ensembl chr 7:86,973,069...87,050,827
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    cellular process 18340
      cell cycle process 1175
        regulation of cell cycle process 659
          regulation of cell cycle phase transition 374
            regulation of cell cycle G1/S phase transition 145
              negative regulation of cell cycle G1/S phase transition + 73
              positive regulation of cell cycle G1/S phase transition + 48
              regulation of G1/S transition of mitotic cell cycle + 124
Path 2
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of biological process 12769
        regulation of cellular process 12228
          regulation of cell cycle 1016
            regulation of cell cycle process 659
              regulation of cell cycle phase transition 374
                regulation of cell cycle G1/S phase transition 145
                  negative regulation of cell cycle G1/S phase transition + 73
                  positive regulation of cell cycle G1/S phase transition + 48
                  regulation of G1/S transition of mitotic cell cycle + 124
paths to the root