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ONTOLOGY REPORT - ANNOTATIONS

Term:secondary alcohol biosynthetic process
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Accession:GO:1902653 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of secondary alcohol.
Synonyms:exact_synonym: secondary alcohol anabolism;   secondary alcohol biosynthesis;   secondary alcohol formation;   secondary alcohol synthesis


show annotations for term's descendants           Sort by:
cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAA2 acetyl-CoA acyltransferase 2 involved_in NAS (PMID:8241273) UniProt PMID:8241273 NCBI chr18:49,782,164...49,813,533
Ensembl chr18:49,782,164...49,813,953 		JBrowse link
G ACLY ATP citrate lyase involved_in TAS (PMID:1371749) BHF-UCL PMID:1371749 NCBI chr17:41,866,917...41,930,545
Ensembl chr17:41,866,917...41,930,542 		JBrowse link
G APOA1 apolipoprotein A1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8647961) Ensembl
MGI		 PMID:8647961 GO_REF:0000107 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G ARV1 ARV1 homolog, fatty acid homeostasis modulator involved_in TAS Reactome Reactome:R-HSA-191273 NCBI chr 1:230,979,094...231,000,733
Ensembl chr 1:230,978,981...231,000,733 		JBrowse link
G CES1 carboxylesterase 1 involved_in IDA (PMID:11015575) BHF-UCL PMID:11015575 NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337 		JBrowse link
G CFTR CF transmembrane conductance regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17085523) Ensembl
MGI		 PMID:17085523 GO_REF:0000107 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971 		JBrowse link
G CHEK2 checkpoint kinase 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr22:28,687,743...28,741,834
Ensembl chr22:28,687,743...28,742,422 		JBrowse link
G CYB5R3 cytochrome b5 reductase 3 involved_in IEA UniProt GO_REF:0000043 NCBI chr22:42,617,840...42,649,392
Ensembl chr22:42,615,730...42,720,870 		JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 involved_in IEA
TAS		 UniProt
Reactome		 GO_REF:0000043 Reactome:R-HSA-191273 NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803 		JBrowse link
G DHCR24 24-dehydrocholesterol reductase involved_in
acts_upstream_of_or_within		 IEA
TAS
ISS
IMP		 (PMID:11519011) UniProt
Reactome
Ensembl
MGI		 PMID:11519011 GO_REF:0000024 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 Reactome:R-HSA-191273 NCBI chr 1:54,849,627...54,887,195
Ensembl chr 1:54,849,627...54,887,195 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase involved_in ISO
IEA
IBA
IMP		 (PMID:9465114) RGD
UniProt
TreeGrafter
GO_Central		 PMID:9465114 PMID:9831636 PMID:10329655 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 GO_REF:0000104 GO_REF:0000118 RGD:2316918 RGD:632010 NCBI chr11:71,434,411...71,448,393
Ensembl chr11:71,428,193...71,452,868 		JBrowse link
G EBP EBP cholestenol delta-isomerase involved_in ISO
IEA
IBA
IDA		 (PMID:9894009) RGD
TreeGrafter
GO_Central
Ensembl
UniProt		 PMID:9894009 PMID:11171067 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 RGD:628445 NCBI chr  X:48,521,808...48,528,716
Ensembl chr  X:48,521,799...48,528,716 		JBrowse link
G FDFT1 farnesyl-diphosphate farnesyltransferase 1 involved_in ISO
IEA
IBA		 RGD
TreeGrafter
GO_Central
UniProt		 PMID:16440058 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118 RGD:1626611 NCBI chr 8:11,795,582...11,839,309
Ensembl chr 8:11,795,573...11,839,395 		JBrowse link
G FDPS farnesyl diphosphate synthase involved_in IEA
TAS		 (PMID:2690933) UniProt
PINC		 PMID:2690933 GO_REF:0000043 NCBI chr 1:155,308,866...155,320,665
Ensembl chr 1:155,308,748...155,320,666 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase involved_in IMP (PMID:12027950) BHF-UCL PMID:12027950 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase involved_in
acts_upstream_of_or_within		 IEA
ISO
IDA		 (PMID:15845870), (PMID:7798939), (PMID:8647961)
(PMID:23063590)		 UniProt
MGI
CACAO
Ensembl		 PMID:7798939 PMID:8647961 PMID:15845870 PMID:23063590 GO_REF:0000043 GO_REF:0000107 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 involved_in IEA
TAS		 UniProt
Reactome		 GO_REF:0000043 Reactome:R-HSA-191273 NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512 		JBrowse link
G HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:119,747,996...119,768,932
Ensembl chr 1:119,748,002...119,768,905 		JBrowse link
G HSD17B7 hydroxysteroid 17-beta dehydrogenase 7 involved_in
acts_upstream_of_or_within		 TAS
ISO
IEA
IBA
IDA		 (PMID:12829805) Reactome
MGI
TreeGrafter
GO_Central
UniProt		 PMID:12829805 GO_REF:0000033 GO_REF:0000118 Reactome:R-HSA-191273 NCBI chr 1:162,790,702...162,812,823
Ensembl chr 1:162,790,702...162,812,823 		JBrowse link
G IDI1 isopentenyl-diphosphate delta isomerase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr10:1,039,152...1,056,704
Ensembl chr10:1,039,152...1,049,119 		JBrowse link
G IDI2 isopentenyl-diphosphate delta isomerase 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr10:1,018,910...1,025,859
Ensembl chr10:1,018,910...1,025,859 		JBrowse link
G INSIG1 insulin induced gene 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
IDA		 (PMID:16955138)
(PMID:32322062)		 Ensembl
MGI
GO_Central
TreeGrafter
UniProt		 PMID:16955138 PMID:32322062 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:155,297,878...155,310,235
Ensembl chr 7:155,297,776...155,310,235 		JBrowse link
G INSIG2 insulin induced gene 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
IDA		 (PMID:16955138)
(PMID:32322062)		 Ensembl
MGI
TreeGrafter
GO_Central
UniProt		 PMID:16955138 PMID:32322062 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:118,088,471...118,110,997
Ensembl chr 2:118,088,452...118,110,997 		JBrowse link
G LBR lamin B receptor involved_in IDA
IEA
IBA
TAS
IMP		 (PMID:16784888)
(PMID:27336722)		 UniProt
GO_Central
Ensembl
Reactome		 PMID:16784888 PMID:27336722 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 Reactome:R-HSA-191273 NCBI chr 1:225,401,502...225,428,821
Ensembl chr 1:225,401,502...225,428,925 		JBrowse link
G LIPA lipase A, lysosomal acid type involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25147230), (PMID:29599133) Ensembl
MGI		 PMID:25147230 PMID:29599133 GO_REF:0000107 NCBI chr10:89,213,572...89,251,775
Ensembl chr10:89,213,569...89,414,557 		JBrowse link
G LSS lanosterol synthase involved_in ISO
IBA
IEA
TAS
IMP		 (PMID:17186944) RGD
GO_Central
TreeGrafter
Reactome
BHF-UCL		 PMID:1429550 PMID:16440058 PMID:17186944 GO_REF:0000033 GO_REF:0000118 RGD:1626611 RGD:2316919 Reactome:R-HSA-191273 NCBI chr21:46,188,446...46,228,774
Ensembl chr21:46,188,141...46,228,824 		JBrowse link
G MSMO1 methylsterol monooxygenase 1 involved_in TAS
IEA		 Reactome
UniProt		 GO_REF:0000041 GO_REF:0000043 Reactome:R-HSA-191273 NCBI chr 4:165,327,669...165,343,164
Ensembl chr 4:165,327,667...165,343,164 		JBrowse link
G MVD mevalonate diphosphate decarboxylase involved_in IEA
NAS		 (PMID:14680974) UniProt PMID:14680974 GO_REF:0000041 GO_REF:0000043 NCBI chr16:88,651,940...88,663,091
Ensembl chr16:88,651,935...88,663,161 		JBrowse link
G MVK mevalonate kinase involved_in IEA
IBA
IDA		 (PMID:1377680) UniProt
TreeGrafter
GO_Central		 PMID:1377680 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118 NCBI chr12:109,573,272...109,598,125
Ensembl chr12:109,573,255...109,598,125 		JBrowse link
G NPC1L1 NPC1 like intracellular cholesterol transporter 1 involved_in IMP (PMID:17140581) HGNC-UCL PMID:17140581 NCBI chr 7:44,512,535...44,541,330
Ensembl chr 7:44,512,535...44,541,330 		JBrowse link
G NSDHL NAD(P) dependent steroid dehydrogenase-like involved_in IEA
TAS		 (PMID:10710235) UniProt
PINC		 PMID:10710235 GO_REF:0000043 Reactome:R-HSA-191273 NCBI chr  X:152,831,063...152,869,729
Ensembl chr  X:152,830,967...152,869,729 		JBrowse link
G PLPP6 phospholipid phosphatase 6 involved_in TAS Reactome Reactome:R-HSA-191273 NCBI chr 9:4,662,294...4,665,258
Ensembl chr 9:4,662,294...4,665,258 		JBrowse link
G PMVK phosphomevalonate kinase involved_in TAS
IEA
IBA
IDA		 (PMID:8663599) Reactome
TreeGrafter
GO_Central
UniProt
InterPro		 PMID:8663599 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118 Reactome:R-HSA-191273 NCBI chr 1:154,924,740...154,942,658
Ensembl chr 1:154,924,740...154,936,719 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374 		JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:56,645,314...56,715,335
Ensembl chr 1:56,645,314...56,715,335 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:9329978) Ensembl
MGI		 PMID:9329978 GO_REF:0000107 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002 		JBrowse link
G STK33 serine/threonine kinase 33 involved_in IEA UniProt GO_REF:0000043 NCBI chr11:8,334,824...8,594,228
Ensembl chr11:8,391,868...8,594,289 		JBrowse link
G TM7SF2 transmembrane 7 superfamily member 2 involved_in IDA
IEA
IBA
TAS		 (PMID:16784888) UniProt
GO_Central
Reactome
Ensembl		 PMID:16784888 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 Reactome:R-HSA-191273 NCBI chr11:65,111,872...65,116,230
Ensembl chr11:65,111,845...65,116,384 		JBrowse link
cholesterol biosynthetic process via 24,25-dihydrolanosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 ISO RGD PMID:7581240 RGD:2316902 NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803 		JBrowse link
cholesterol biosynthetic process via desmosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHCR24 24-dehydrocholesterol reductase involved_in IMP
TAS		 (PMID:11519011) UniProt
Reactome		 PMID:11519011 Reactome:R-HSA-6807047 NCBI chr 1:54,849,627...54,887,195
Ensembl chr 1:54,849,627...54,887,195 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase involved_in TAS Reactome Reactome:R-HSA-6807047 NCBI chr11:71,434,411...71,448,393
Ensembl chr11:71,428,193...71,452,868 		JBrowse link
G EBP EBP cholestenol delta-isomerase involved_in TAS Reactome Reactome:R-HSA-6807047 NCBI chr  X:48,521,808...48,528,716
Ensembl chr  X:48,521,799...48,528,716 		JBrowse link
G SC5D sterol-C5-desaturase involved_in TAS Reactome Reactome:R-HSA-6807047 NCBI chr11:121,292,771...121,313,410
Ensembl chr11:121,292,681...121,313,410 		JBrowse link
cholesterol biosynthetic process via lathosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHCR24 24-dehydrocholesterol reductase involved_in TAS Reactome Reactome:R-HSA-6807062 NCBI chr 1:54,849,627...54,887,195
Ensembl chr 1:54,849,627...54,887,195 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase involved_in TAS Reactome Reactome:R-HSA-6807062 NCBI chr11:71,434,411...71,448,393
Ensembl chr11:71,428,193...71,452,868 		JBrowse link
G EBP EBP cholestenol delta-isomerase involved_in TAS Reactome Reactome:R-HSA-6807062 NCBI chr  X:48,521,808...48,528,716
Ensembl chr  X:48,521,799...48,528,716 		JBrowse link
G SC5D sterol-C5-desaturase involved_in ISO
IBA
IEA
TAS		 RGD
GO_Central
Ensembl
Reactome		 PMID:7961720 GO_REF:0000033 GO_REF:0000107 RGD:2316911 Reactome:R-HSA-6807062 NCBI chr11:121,292,771...121,313,410
Ensembl chr11:121,292,681...121,313,410 		JBrowse link
ergosterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT2 acetyl-CoA acetyltransferase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:159,762,045...159,779,112
Ensembl chr 6:159,762,045...159,779,112 		JBrowse link
G FDFT1 farnesyl-diphosphate farnesyltransferase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:11,795,582...11,839,309
Ensembl chr 8:11,795,573...11,839,395 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G LSS lanosterol synthase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr21:46,188,446...46,228,774
Ensembl chr21:46,188,141...46,228,824 		JBrowse link
G MVK mevalonate kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:109,573,272...109,598,125
Ensembl chr12:109,573,255...109,598,125 		JBrowse link
G SIGMAR1 sigma non-opioid intracellular receptor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:34,634,722...34,637,787
Ensembl chr 9:34,634,722...34,637,844 		JBrowse link
G SQLE squalene epoxidase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:124,998,505...125,022,283
Ensembl chr 8:124,998,497...125,022,283 		JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in ISO
IDA		 (PMID:1917954) RGD
BHF-UCL		 PMID:1917954 PMID:9225228 RGD:10059686 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G ERLIN1 ER lipid raft associated 1 involved_in IMP (PMID:24217618) UniProt PMID:24217618 NCBI chr10:100,150,094...100,186,029
Ensembl chr10:100,150,094...100,186,033 		JBrowse link
G ERLIN2 ER lipid raft associated 2 involved_in IMP (PMID:24217618) UniProt PMID:24217618 NCBI chr 8:37,736,634...37,758,422
Ensembl chr 8:37,736,601...37,758,422 		JBrowse link
G IDI2 isopentenyl-diphosphate delta isomerase 2 acts_upstream_of_or_within ISO (PMID:17202134) MGI PMID:17202134 NCBI chr10:1,018,910...1,025,859
Ensembl chr10:1,018,910...1,025,859 		JBrowse link
G MIR185 microRNA 185 acts_upstream_of IGI
IDA		 (PMID:24296663)
(PMID:23951060)		 BHF-UCL PMID:23951060 PMID:24296663 NCBI chr22:20,033,139...20,033,220
Ensembl chr22:20,033,139...20,033,220 		JBrowse link
G MIR30C1 microRNA 30c-1 acts_upstream_of ISS (PMID:27365390) BHF-UCL PMID:27365390 NCBI chr 1:40,757,284...40,757,372
Ensembl chr 1:40,757,284...40,757,372 		JBrowse link
G MIR30C2 microRNA 30c-2 acts_upstream_of ISS (PMID:27365390) BHF-UCL PMID:27365390 NCBI chr 6:71,376,960...71,377,031
Ensembl chr 6:71,376,960...71,377,031 		JBrowse link
G MIR342 microRNA 342 acts_upstream_of IDA (PMID:23951060) BHF-UCL PMID:23951060 NCBI chr14:100,109,655...100,109,753
Ensembl chr14:100,109,655...100,109,753 		JBrowse link
G MIR548P microRNA 548p involved_in IDA (PMID:28336556) BHF-UCL PMID:28336556 NCBI chr 5:100,816,482...100,816,565
Ensembl chr 5:100,816,482...100,816,565 		JBrowse link
G MIR98 microRNA 98 involved_in IDA (PMID:30195495) BHF-UCL PMID:30195495 NCBI chr  X:53,556,223...53,556,341
Ensembl chr  X:53,556,223...53,556,341 		JBrowse link
G SCAP SREBF chaperone involved_in NAS (PMID:11969205) UniProt PMID:11969205 NCBI chr 3:47,413,681...47,477,127
Ensembl chr 3:47,413,681...47,477,126 		JBrowse link
G SOD1 superoxide dismutase 1 involved_in IDA (PMID:15473258) UniProt PMID:15473258 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
positive regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr21:42,199,689...42,297,244
Ensembl chr21:42,199,689...42,297,244 		JBrowse link
G ABCG4 ATP binding cassette subfamily G member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:119,149,052...119,162,666
Ensembl chr11:119,149,052...119,162,653 		JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163 		JBrowse link
G FDPS farnesyl diphosphate synthase ISO RGD PMID:18637708 RGD:2316295 NCBI chr 1:155,308,866...155,320,665
Ensembl chr 1:155,308,748...155,320,666 		JBrowse link
G FGF1 fibroblast growth factor 1 involved_in IDA (PMID:19229075) BHF-UCL PMID:19229075 NCBI chr 5:142,592,178...142,698,070
Ensembl chr 5:142,592,178...142,698,070 		JBrowse link
G MIR182 microRNA 182 involved_in IGI (PMID:23823476) BHF-UCL PMID:23823476 NCBI chr 7:129,770,383...129,770,492
Ensembl chr 7:129,770,383...129,770,492 		JBrowse link
G MIR96 microRNA 96 involved_in
acts_upstream_of		 IGI
IDA		 (PMID:23823476)
(PMID:30460077)		 BHF-UCL PMID:23823476 PMID:30460077 NCBI chr 7:129,774,692...129,774,769
Ensembl chr 7:129,774,692...129,774,769 		JBrowse link
G NPY1R neuropeptide Y receptor Y1 ISO RGD PMID:32976883 RGD:405096663 NCBI chr 4:163,323,962...163,344,689
Ensembl chr 4:163,323,962...163,344,832 		JBrowse link
G POR cytochrome p450 oxidoreductase ISO RGD PMID:19264869 RGD:2316785 NCBI chr 7:75,915,155...75,986,855
Ensembl chr 7:75,899,200...75,986,855 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in NAS (PMID:8557660) UniProt PMID:8557660 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374 		JBrowse link
G QKI QKI, KH domain containing RNA binding involved_in ISS UniProt GO_REF:0000024 NCBI chr 6:163,414,718...163,578,592
Ensembl chr 6:163,414,000...163,578,592 		JBrowse link
G SCAP SREBF chaperone involved_in IDA (PMID:32322062) UniProt PMID:32322062 NCBI chr 3:47,413,681...47,477,127
Ensembl chr 3:47,413,681...47,477,126 		JBrowse link
G SCP2 sterol carrier protein 2 ISO RGD PMID:2554812 RGD:9850260 NCBI chr 1:52,927,276...53,051,698
Ensembl chr 1:52,927,276...53,051,698 		JBrowse link
G SEC14L2 SEC14 like lipid binding 2 ISO RGD PMID:11226224 RGD:727312 NCBI chr22:30,397,018...30,425,303
Ensembl chr22:30,396,941...30,425,303 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IMP
IDA		 (PMID:9329978)
(PMID:16046411)
(PMID:12177166)
(PMID:12177166), (PMID:32322062)		 Ensembl
MGI
UniProt		 PMID:9329978 PMID:12177166 PMID:16046411 PMID:32322062 GO_REF:0000107 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 involved_in IDA (PMID:12177166), (PMID:32322062) UniProt PMID:12177166 PMID:32322062 NCBI chr22:41,833,105...41,907,305
Ensembl chr22:41,833,105...41,907,306 		JBrowse link
regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 NOT|involved_in IDA (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chr 9:137,007,234...137,028,922
Ensembl chr 9:137,007,234...137,028,915 		JBrowse link
G APOB apolipoprotein B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16455790) Ensembl
MGI		 PMID:16455790 GO_REF:0000107 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073 		JBrowse link
G AQP8 aquaporin 8 involved_in IMP (PMID:30579780) UniProt PMID:30579780 NCBI chr16:25,216,947...25,228,932
Ensembl chr16:25,215,731...25,228,932 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase ISO RGD PMID:10329655 RGD:632010 NCBI chr11:71,434,411...71,448,393
Ensembl chr11:71,428,193...71,452,868 		JBrowse link
G ERLIN1 ER lipid raft associated 1 involved_in IDA (PMID:24217618) ComplexPortal PMID:24217618 NCBI chr10:100,150,094...100,186,029
Ensembl chr10:100,150,094...100,186,033 		JBrowse link
G ERLIN2 ER lipid raft associated 2 involved_in IDA (PMID:24217618) ComplexPortal PMID:24217618 NCBI chr 8:37,736,634...37,758,422
Ensembl chr 8:37,736,601...37,758,422 		JBrowse link
G LPCAT3 lysophosphatidylcholine acyltransferase 3 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:6,976,185...7,018,476
Ensembl chr12:6,976,185...7,018,477 		JBrowse link
G MBTPS1 membrane bound transcription factor peptidase, site 1 involved_in TAS Reactome Reactome:R-HSA-1655829 NCBI chr16:84,053,763...84,116,942
Ensembl chr16:84,053,761...84,116,942 		JBrowse link
G MBTPS2 membrane bound transcription factor peptidase, site 2 involved_in TAS Reactome Reactome:R-HSA-1655829 NCBI chr  X:21,839,617...21,885,423
Ensembl chr  X:21,839,617...21,885,423 		JBrowse link
G PEX2 peroxisomal biogenesis factor 2 acts_upstream_of_or_within ISO (PMID:14673138) MGI PMID:14673138 NCBI chr 8:76,980,258...77,001,044
Ensembl chr 8:76,980,258...77,001,044 		JBrowse link
G SCAP SREBF chaperone involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:16054043) Ensembl
MGI
TreeGrafter
GO_Central		 PMID:16054043 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:47,413,681...47,477,127
Ensembl chr 3:47,413,681...47,477,126 		JBrowse link
G SEC14L2 SEC14 like lipid binding 2 involved_in NAS (PMID:11226224) UniProt PMID:11226224 NCBI chr22:30,397,018...30,425,303
Ensembl chr22:30,396,941...30,425,303 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19669
    metabolic process 12464
      small molecule metabolic process 2010
        alcohol metabolic process 419
          secondary alcohol metabolic process 181
            secondary alcohol biosynthetic process 72
              (17Z)-protosta-17(20),24-dien-3beta-ol biosynthetic process 0
              2-hydroxy-but-3-enyl glucosinolate biosynthetic process 0
              acetoin biosynthetic process 0
              asperfuranone biosynthetic process + 0
              butanediol biosynthetic process 0
              cholesterol biosynthetic process + 69
              conidiogenone biosynthetic process 0
              culmorin biosynthetic process 0
              ecdysone biosynthetic process 0
              ergosterol biosynthetic process + 7
              menthol biosynthetic process 0
              propan-2-ol biosynthetic process 0
              viridicatumtoxin biosynthetic process 0
              vitamin D3 biosynthetic process 0
              vomitoxin biosynthetic process 0
              zymosterol biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 19669
    metabolic process 12464
      biosynthetic process 9289
        organic substance biosynthetic process 9224
          organic hydroxy compound biosynthetic process 280
            alcohol biosynthetic process 158
              secondary alcohol biosynthetic process 72
                (17Z)-protosta-17(20),24-dien-3beta-ol biosynthetic process 0
                2-hydroxy-but-3-enyl glucosinolate biosynthetic process 0
                acetoin biosynthetic process 0
                asperfuranone biosynthetic process + 0
                butanediol biosynthetic process 0
                cholesterol biosynthetic process + 69
                conidiogenone biosynthetic process 0
                culmorin biosynthetic process 0
                ecdysone biosynthetic process 0
                ergosterol biosynthetic process + 7
                menthol biosynthetic process 0
                propan-2-ol biosynthetic process 0
                viridicatumtoxin biosynthetic process 0
                vitamin D3 biosynthetic process 0
                vomitoxin biosynthetic process 0
                zymosterol biosynthetic process 0
paths to the root