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ONTOLOGY REPORT - ANNOTATIONS

Term:secondary alcohol metabolic process
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Accession:GO:1902652 term browser browse the term
Definition:The chemical reactions and pathways involving secondary alcohol.
Synonyms:exact_synonym: secondary alcohol metabolism


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calcitriol biosynthetic process from calciol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:179,694,647...179,709,083 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 involved_in ISO
IEA
IBA 		(PMID:15465040)
GO_REF:0000117
GO_REF:0000107
GO_REF:0000033 		RGD
UniProt
Ensembl
GO_Central		 PMID:15465040 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:83,713,293...83,743,215 		JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 involved_in ISO
IEA
IBA 		(PMID:15795327), (PMID:16549446), (PMID:17023519), (PMID:22862690), (PMID:9415400)
GO_REF:0000117
GO_REF:0000107
(PMID:15972816)
GO_REF:0000033 		RGD
UniProt
Ensembl
GO_Central		 PMID:9415400 PMID:15795327 PMID:15972816 PMID:16549446 PMID:17023519 More... GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 7:64,756,626...64,761,570
Ensembl chr 7:64,756,626...64,761,570 		JBrowse link
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 involved_in ISO
IEA 		(PMID:15465040), (PMID:18511070)
GO_REF:0000107 		RGD
Ensembl		 PMID:15465040 PMID:18511070 GO_REF:0000107 NCBI chr 1:178,166,984...178,232,191
Ensembl chr 1:178,219,704...178,232,423 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07021955.1 involved_in IEA GO_REF:0000041
GO_REF:0000043
GO_REF:0000104 		UniProt GO_REF:0000041 GO_REF:0000043 GO_REF:0000104
G Acat2 acetyl-CoA acetyltransferase 2 involved_in TAS PMID:10806397 UniProt PMID:10806397 RGD:2326086 NCBI chr 1:50,100,840...50,118,886
Ensembl chr 1:50,100,817...50,135,095 		JBrowse link
G Apoa1 apolipoprotein A1 acts_upstream_of_or_within ISO MGI:2180783 (PMID:8647961) RGD PMID:8647961 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729 		JBrowse link
G Ces1d carboxylesterase 1D involved_in ISO (PMID:11015575) RGD PMID:11015575 NCBI chr19:30,046,494...30,085,039
Ensembl chr19:30,046,449...30,085,449 		JBrowse link
G Cftr CF transmembrane conductance regulator acts_upstream_of_or_within ISO
IEA 		MGI:1856709 (PMID:17085523)
GO_REF:0000107 		RGD
Ensembl		 PMID:17085523 GO_REF:0000107 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643 		JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:116,186,729...116,204,290
Ensembl chr 7:116,186,729...116,204,306 		JBrowse link
G Cyp51 cytochrome P450, family 51 involved_in IEA GO_REF:0000043
GO_REF:0000117 		UniProt GO_REF:0000043 GO_REF:0000117 NCBI chr 4:30,991,693...31,010,147
Ensembl chr 4:30,991,613...31,010,450 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase involved_in
acts_upstream_of_or_within 		ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000043
GO_REF:0000107
GO_REF:0000041
(PMID:14684813)
MGI:3027024 (PMID:14684813), (PMID:16321981), (PMID:16513830)
(PMID:11519011) 		UniProt
Ensembl
RGD		 PMID:11519011 PMID:14684813 PMID:16321981 PMID:16513830 GO_REF:0000024 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 NCBI chr 5:126,573,366...126,599,940
Ensembl chr 5:126,573,338...126,599,936 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase involved_in TAS
IEA
IBA
ISO
IMP
IC
IDA 		GO_REF:0000107
GO_REF:0000043
GO_REF:0000041
GO_REF:0000104
GO_REF:0000033
(PMID:9465114) 		Ensembl
UniProt
GO_Central
RGD		 PMID:9465114 PMID:12031495 PMID:9831636 PMID:10666310 PMID:10329655 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107, RGD:625561, RGD:2316918, RGD:2316916, RGD:632010 NCBI chr 1:208,444,434...208,460,408
Ensembl chr 1:208,444,434...208,461,382 		JBrowse link
G Ebp EBP, cholestenol delta-isomerase involved_in IDA
IEA
IBA
ISO
TAS 		GO_REF:0000107
GO_REF:0000043
GO_REF:0000033
(PMID:9894009)
GO_REF:0000041 		Ensembl
UniProt
GO_Central
RGD		 PMID:9894009 PMID:11171067 PMID:11171067 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107, RGD:628445, RGD:628445 NCBI chr  X:16,971,372...16,977,782
Ensembl chr  X:16,971,405...16,977,781 		JBrowse link
G ENSRNOG00000062441 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G Fdft1 farnesyl diphosphate farnesyl transferase 1 involved_in IMP
IEA
IBA 		GO_REF:0000043
GO_REF:0000033 		UniProt
GO_Central
RGD		 PMID:16440058 GO_REF:0000033 GO_REF:0000043, RGD:1626611 NCBI chr15:41,588,114...41,616,168
Ensembl chr15:41,588,117...41,616,168 		JBrowse link
G Fdps farnesyl diphosphate synthase involved_in TAS
IEA 		GO_REF:0000117
GO_REF:0000043 		UniProt
RGD		 PMID:1321149 GO_REF:0000043 GO_REF:0000117, RGD:728501 NCBI chr 2:176,795,192...176,804,816
Ensembl chr 2:176,795,192...176,807,136 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase involved_in ISO
IEA 		(PMID:12027950)
GO_REF:0000107 		RGD
Ensembl		 PMID:12027950 GO_REF:0000107 NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:157,352,373...157,372,144 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:23063590)
GO_REF:0000107
(PMID:15845870), (PMID:7798939), (PMID:8647961)
GO_REF:0000043 		RGD
Ensembl
UniProt		 PMID:7798939 PMID:8647961 PMID:15845870 PMID:23063590 GO_REF:0000043 GO_REF:0000107 NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:188,564,348...188,590,872
Ensembl chr 2:188,547,767...188,592,242 		JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 involved_in
acts_upstream_of_or_within 		ISO
IEA
IBA
ISS 		(PMID:12829805)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000024 		RGD
Ensembl
GO_Central
UniProt		 PMID:12829805 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr13:84,702,875...84,722,810
Ensembl chr13:84,705,631...84,722,754 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 involved_in TAS
IEA 		GO_REF:0000043 UniProt
RGD		 PMID:9228075 GO_REF:0000043, RGD:729078 NCBI chr17:66,539,761...66,547,524
Ensembl chr17:66,539,763...66,547,524 		JBrowse link
G Idi2 isopentenyl-diphosphate delta isomerase 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,331,385...61,334,987 JBrowse link
G Idi2-ps1 isopentenyl-diphosphate delta isomerase 2, pseudogene 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,420,357...61,423,924 JBrowse link
G Idi2l2 isopentenyl-diphosphate delta isomerase 2 like 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,372,853...61,386,459 JBrowse link
G Idi2l3 isopentenyl-diphosphate delta isomerase 2 like 3 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,518,138...61,535,484 JBrowse link
G Insig1 insulin induced gene 1 involved_in
acts_upstream_of_or_within 		ISO
IBA 		(PMID:32322062)
MGI:1920249 (PMID:16955138)
GO_REF:0000033 		RGD
GO_Central		 PMID:16955138 PMID:32322062 GO_REF:0000033 NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:8,049,556...8,057,778 		JBrowse link
G Insig2 insulin induced gene 2 involved_in
acts_upstream_of_or_within 		ISS
IEA
ISO
IBA 		GO_REF:0000024
GO_REF:0000107
MGI:1916289 (PMID:16955138)
GO_REF:0000033
(PMID:32322062) 		UniProt
Ensembl
RGD
GO_Central		 PMID:16955138 PMID:32322062 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr13:35,025,160...35,052,937
Ensembl chr13:35,025,164...35,047,658 		JBrowse link
G Lbr lamin B receptor involved_in ISO
IEA
IBA
ISS 		(PMID:16784888), (PMID:27336722)
GO_REF:0000043
GO_REF:0000104
GO_REF:0000107
(PMID:18785926), (PMID:22140257)
GO_REF:0000033
GO_REF:0000041
GO_REF:0000024 		RGD
UniProt
Ensembl
GO_Central		 PMID:16784888 PMID:18785926 PMID:22140257 PMID:27336722 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 NCBI chr13:96,071,058...96,095,709
Ensembl chr13:96,071,081...96,095,709 		JBrowse link
G Lipa lipase A, lysosomal acid type acts_upstream_of_or_within ISO
IEA 		MGI:2451080 (PMID:25147230), (PMID:29599133)
GO_REF:0000107 		RGD
Ensembl		 PMID:25147230 PMID:29599133 GO_REF:0000107 NCBI chr 1:241,437,524...241,470,936
Ensembl chr 1:241,437,524...241,470,740 		JBrowse link
G LOC102550988 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,451,920...61,457,799 JBrowse link
G LOC102551575 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,504,294...61,507,015 JBrowse link
G LOC120097764 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,338,622...61,349,795 JBrowse link
G LOC120102490 insulin-induced gene 1 protein-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:67,330,399...67,331,371
Ensembl chr 4:68,297,489...68,298,247 		JBrowse link
G LOC134482631 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G LOC134482634 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G LOC134482635 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G LOC134482779 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G LOC134482866 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G LOC134484812 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G Lss lanosterol synthase involved_in IMP
IEA
IBA
IDA
ISO 		GO_REF:0000117
GO_REF:0000033
GO_REF:0000107
PMID:7568116
(PMID:17186944) 		UniProt
GO_Central
Ensembl
RGD		 PMID:17186944 PMID:16440058 PMID:7568116 PMID:1429550 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117, RGD:1626611, RGD:728996, RGD:2316919 NCBI chr20:12,090,641...12,118,230
Ensembl chr20:12,073,543...12,118,253 		JBrowse link
G Msmo1 methylsterol monooxygenase 1 involved_in IEA GO_REF:0000041
GO_REF:0000043 		UniProt GO_REF:0000041 GO_REF:0000043 NCBI chr16:29,747,113...29,764,360
Ensembl chr16:29,747,137...29,764,445 		JBrowse link
G Mvd mevalonate diphosphate decarboxylase involved_in NAS
IEA 		GO_REF:0000043
GO_REF:0000041 		UniProt
RGD		 PMID:11767099 GO_REF:0000041 GO_REF:0000043, RGD:729305 NCBI chr19:67,404,911...67,414,974
Ensembl chr19:67,404,911...67,422,366 		JBrowse link
G Mvk mevalonate kinase involved_in TAS
IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
GO_REF:0000043
(PMID:1377680) 		GO_Central
Ensembl
UniProt
RGD		 PMID:1377680 PMID:2158094 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107, RGD:728935 NCBI chr12:47,802,002...47,819,503
Ensembl chr12:47,802,002...47,819,503 		JBrowse link
G Npc1l1 NPC1 like intracellular cholesterol transporter 1 involved_in ISO (PMID:17140581) RGD PMID:17140581 NCBI chr14:81,071,448...81,091,113
Ensembl chr14:85,285,390...85,305,050 		JBrowse link
G Nsdhl NAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr  X:155,817,301...155,848,224
Ensembl chr  X:155,817,340...155,848,220 		JBrowse link
G Pmvk phosphomevalonate kinase involved_in ISO
IEA
IBA
NAS 		(PMID:8663599)
GO_REF:0000107
GO_REF:0000043
GO_REF:0000104
GO_REF:0000002
GO_REF:0000033
PMID:10191291 		RGD
Ensembl
UniProt
InterPro
GO_Central		 PMID:8663599 PMID:10191291 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107, RGD:8553625 NCBI chr 2:177,174,344...177,184,076
Ensembl chr 2:177,174,335...177,184,080 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:55,967,351...56,003,450 		JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:125,042,179...125,108,324 		JBrowse link
G Rusc1 RUN and SH3 domain containing 1 involved_in IEA GO_REF:0000043
GO_REF:0000117 		UniProt GO_REF:0000043 GO_REF:0000117 NCBI chr 2:174,487,921...174,497,266
Ensembl chr 2:176,785,711...176,794,178 		JBrowse link
G Sc5d sterol-C5-desaturase involved_in ISO
IEA 		(PMID:10786622)
GO_REF:0000107 		RGD
Ensembl		 PMID:10786622 GO_REF:0000107 NCBI chr 8:51,526,669...51,538,277
Ensembl chr 8:51,529,346...51,538,277 		JBrowse link
G Spatc1l spermatogenesis and centriole associated 1-like involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr20:12,074,040...12,083,873
Ensembl chr20:12,073,543...12,118,253 		JBrowse link
G Sqle squalene epoxidase involved_in ISO (PMID:33791309) RGD PMID:33791309 NCBI chr 7:92,758,175...92,773,049
Ensembl chr 7:92,757,409...92,773,050 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 acts_upstream_of ISO
IEA 		MGI:2177958 (PMID:9329978)
GO_REF:0000107 		RGD
Ensembl		 PMID:9329978 GO_REF:0000107 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164 		JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 involved_in IEA
ISO 		GO_REF:0000041
GO_REF:0000107
GO_REF:0000043
GO_REF:0000104
(PMID:18785926)
(PMID:16784888) 		UniProt
Ensembl
RGD		 PMID:16784888 PMID:18785926 GO_REF:0000041 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 NCBI chr 1:212,785,217...212,789,572
Ensembl chr 1:212,785,217...212,789,557 		JBrowse link
cholesterol biosynthetic process via 24,25-dihydrolanosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp51 cytochrome P450, family 51 involved_in IDA
IBA 		GO_REF:0000033 GO_Central
RGD		 PMID:7581240 GO_REF:0000033, RGD:2316902 NCBI chr 4:30,991,693...31,010,147
Ensembl chr 4:30,991,613...31,010,450 		JBrowse link
cholesterol biosynthetic process via desmosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhcr24 24-dehydrocholesterol reductase involved_in ISO
IEA 		(PMID:11519011)
GO_REF:0000107 		RGD
Ensembl		 PMID:11519011 GO_REF:0000107 NCBI chr 5:126,573,366...126,599,940
Ensembl chr 5:126,573,338...126,599,936 		JBrowse link
cholesterol biosynthetic process via lathosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhcr7 7-dehydrocholesterol reductase involved_in ISO
IEA 		(PMID:38297129), (PMID:38297130)
GO_REF:0000107 		RGD
Ensembl		 PMID:38297129 PMID:38297130 GO_REF:0000107 NCBI chr 1:208,444,434...208,460,408
Ensembl chr 1:208,444,434...208,461,382 		JBrowse link
G Sc5d sterol-C5-desaturase involved_in IDA
IEA
IBA
ISO 		GO_REF:0000107
GO_REF:0000033
PMID:4019441
(PMID:10786622) 		Ensembl
GO_Central
RGD		 PMID:10786622 PMID:7961720 PMID:4019441 GO_REF:0000033 GO_REF:0000107, RGD:2316911, RGD:405866208 NCBI chr 8:51,526,669...51,538,277
Ensembl chr 8:51,529,346...51,538,277 		JBrowse link
cholesterol catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1d1 aldo-keto reductase family 1, member D1 involved_in ISO
IEA 		(PMID:7508385)
GO_REF:0000107 		RGD
Ensembl		 PMID:7508385 GO_REF:0000107 NCBI chr 4:67,121,288...67,154,543
Ensembl chr 4:67,120,024...67,154,540 		JBrowse link
G Apoe apolipoprotein E acts_upstream_of_or_within ISO (PMID:9826706) RGD PMID:9826706 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
GO_REF:0000041
(PMID:9660774) 		UniProt
Ensembl
RGD		 PMID:9660774 GO_REF:0000024 GO_REF:0000041 GO_REF:0000107 NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:83,713,293...83,743,215 		JBrowse link
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 acts_upstream_of_or_within ISO (PMID:10748047) RGD PMID:10748047 NCBI chr 9:17,230,455...17,306,775
Ensembl chr 9:24,727,817...24,804,060 		JBrowse link
G Cyp46a1 cytochrome P450, family 46, subfamily a, polypeptide 1 involved_in ISO
IEA
IBA 		(PMID:14640697), (PMID:18621681), (PMID:25017465)
GO_REF:0000117
GO_REF:0000002
(PMID:10377398), (PMID:20193040)
GO_REF:0000033 		RGD
UniProt
InterPro
GO_Central		 PMID:10377398 PMID:14640697 PMID:18621681 PMID:20193040 PMID:25017465 GO_REF:0000002 GO_REF:0000033 GO_REF:0000117 NCBI chr 6:133,011,948...133,039,167
Ensembl chr 6:133,011,989...133,041,971 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 involved_in
acts_upstream_of_or_within 		IDA
IEA
ISO 		PMID:1694852
GO_REF:0000117
GO_REF:0000107
GO_REF:0000002
(PMID:11279518), (PMID:15845870)
GO_REF:0000041 		UniProt
Ensembl
InterPro
RGD		 PMID:11279518 PMID:15845870 PMID:1694852 GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 GO_REF:0000117, RGD:70534 NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202 		JBrowse link
G Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 IDA RGD PMID:16081591 RGD:1599972 NCBI chr 1:182,412,216...182,415,447
Ensembl chr 1:191,842,636...191,845,921 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 acts_upstream_of_or_within ISO
IEA 		MGI:1928989 (PMID:10559220), (PMID:11278646)
GO_REF:0000107 		RGD
Ensembl		 PMID:10559220 PMID:11278646 GO_REF:0000107 NCBI chr12:36,957,302...37,023,982
Ensembl chr12:36,957,496...37,023,980 		JBrowse link
cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07021955.1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G Abca1 ATP binding cassette subfamily A member 1 involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:14747463)
GO_REF:0000107
(PMID:11559713) 		RGD
Ensembl		 PMID:11559713 PMID:14747463 GO_REF:0000107 NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473 		JBrowse link
G Abca5 ATP binding cassette subfamily A member 5 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:25125465) 		UniProt
Ensembl
RGD		 PMID:25125465 GO_REF:0000024 GO_REF:0000107 NCBI chr10:95,739,610...95,808,633
Ensembl chr10:95,739,610...95,808,424 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (PMID:15994327) RGD PMID:15994327 NCBI chr20:9,128,056...9,184,312
Ensembl chr20:9,127,803...9,186,563 		JBrowse link
G Angptl3 angiopoietin-like 3 involved_in ISO
IEA 		(PMID:17110602)
GO_REF:0000107 		RGD
Ensembl		 PMID:17110602 GO_REF:0000107 NCBI chr 5:118,818,494...118,825,531
Ensembl chr 5:118,818,499...118,826,444 		JBrowse link
G Aplp2 amyloid beta precursor like protein 2 acts_upstream_of_or_within ISO MGI:88059 (PMID:17920016) RGD PMID:17920016 NCBI chr 8:37,857,407...37,920,487
Ensembl chr 8:37,857,407...37,920,031 		JBrowse link
G Apoa1 apolipoprotein A1 involved_in
acts_upstream_of_or_within 		ISO
IEA
IBA 		(PMID:15464323)
GO_REF:0000043
MGI:104663|MGI:104993|MGI:1857127 (PMID:10357841), (PMID:15466405), (PMID:15995171), (PMID:17071966), (PMID:7751823), (PMID:9327769), (PMID:9795222)
GO_REF:0000033
GO_REF:0000107 		RGD
UniProt
GO_Central
Ensembl		 PMID:7751823 PMID:9327769 PMID:9795222 PMID:10357841 PMID:15464323 More... GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729 		JBrowse link
G Apoa2 apolipoprotein A2 acts_upstream_of_or_within ISO MGI:2157148|MGI:96216 (PMID:10357838), (PMID:8647961) RGD PMID:8647961 PMID:10357838 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:86,174,741...86,179,410 		JBrowse link
G Apoa4 apolipoprotein A4 involved_in IEA
IBA
ISO 		GO_REF:0000107
GO_REF:0000033
(PMID:1935934) 		Ensembl
GO_Central
RGD		 PMID:1935934 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:55,434,168...55,438,164 		JBrowse link
G Apoa5 apolipoprotein A5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:55,446,329...55,460,509
Ensembl chr 8:55,456,899...55,460,507 		JBrowse link
G Apob apolipoprotein B involved_in ISO
IEA 		(PMID:2563166)
GO_REF:0000043
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:2563166 GO_REF:0000043 GO_REF:0000107 NCBI chr 6:36,563,704...36,603,300
Ensembl chr 6:36,563,704...36,611,814 		JBrowse link
G Apoc1 apolipoprotein C1 acts_upstream_of_or_within ISO MGI:2157218 (PMID:7848292) RGD PMID:7848292 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:88,474,663...88,478,155 		JBrowse link
G Apoc3 apolipoprotein C3 acts_upstream_of_or_within ISO MGI:1857128|MGI:3758464 (PMID:11590213), (PMID:8089130), (PMID:8864964) RGD PMID:8089130 PMID:8864964 PMID:11590213 NCBI chr 8:55,428,172...55,430,352
Ensembl chr 8:55,428,024...55,458,679 		JBrowse link
G Apoe apolipoprotein E involved_in
acts_upstream_of_or_within 		ISO
IEA
IBA 		(PMID:3771793), (PMID:9649566)
GO_REF:0000107
MGI:2137814 (PMID:1423598), (PMID:8647961)
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:1423598 PMID:3771793 PMID:8647961 PMID:9649566 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855 		JBrowse link
G Apof apolipoprotein F involved_in
acts_upstream_of_or_within 		IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000043
MGI:3800154 (PMID:22363685) 		GO_Central
UniProt
RGD		 PMID:22363685 GO_REF:0000033 GO_REF:0000043 NCBI chr 7:700,688...702,130
Ensembl chr 7:1,285,222...1,286,659 		JBrowse link
G App amyloid beta precursor protein acts_upstream_of_or_within ISO MGI:2136847|MGI:88047 (PMID:17920016) RGD PMID:17920016 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971 		JBrowse link
G Cat catalase acts_upstream_of_or_within ISO
IEA 		MGI:3053604 (PMID:5087482)
GO_REF:0000107 		RGD
Ensembl		 PMID:5087482 GO_REF:0000107 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha acts_upstream_of_or_within ISO
IEA 		MGI:3848341 (PMID:18974039)
GO_REF:0000107 		RGD
Ensembl		 PMID:18974039 GO_REF:0000107 NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:96,896,171...96,899,309 		JBrowse link
G Ces1d carboxylesterase 1D involved_in ISO (PMID:16024911) RGD PMID:16024911 NCBI chr19:30,046,494...30,085,039
Ensembl chr19:30,046,449...30,085,449 		JBrowse link
G Ch25h cholesterol 25-hydroxylase involved_in
acts_upstream_of_or_within 		ISO
IBA
ISS 		(PMID:33239446)
(PMID:9852097)
GO_REF:0000033
GO_REF:0000024 		RGD
GO_Central
UniProt		 PMID:9852097 PMID:33239446 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:241,428,048...241,429,366
Ensembl chr 1:241,331,619...241,431,190 		JBrowse link
G Cln6 CLN6, transmembrane ER protein involved_in ISO
IEA 		(PMID:16857350)
GO_REF:0000107 		RGD
Ensembl		 PMID:16857350 GO_REF:0000107 NCBI chr 8:63,303,356...63,318,360
Ensembl chr 8:72,198,712...72,213,776 		JBrowse link
G Cln8 CLN8, transmembrane ER and ERGIC protein involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:16086686) 		UniProt
Ensembl
RGD		 PMID:16086686 GO_REF:0000024 GO_REF:0000107 NCBI chr16:81,451,941...81,462,046
Ensembl chr16:81,451,944...81,461,832 		JBrowse link
G Cubn cubilin involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:81,293,619...81,501,694
Ensembl chr17:81,293,619...81,501,694 		JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:116,186,729...116,204,290
Ensembl chr 7:116,186,729...116,204,306 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 involved_in IEA
IBA
ISO
ISS 		GO_REF:0000041
GO_REF:0000107
GO_REF:0000043
GO_REF:0000033
(PMID:18182448), (PMID:21636783)
GO_REF:0000024 		UniProt
Ensembl
GO_Central
RGD		 PMID:18182448 PMID:21636783 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196 		JBrowse link
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:108,653,385...108,660,062
Ensembl chr 7:108,653,378...108,660,995
Ensembl chr 7:108,653,378...108,660,995 		JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:108,719,349...108,726,024
Ensembl chr 7:108,719,349...108,725,763 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 involved_in IDA
IEA
IBA 		GO_REF:0000043
GO_REF:0000033 		UniProt
GO_Central
RGD		 PMID:2175615 GO_REF:0000033 GO_REF:0000043, RGD:1299597 NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:83,713,293...83,743,215 		JBrowse link
G Cyp46a1 cytochrome P450, family 46, subfamily a, polypeptide 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 6:133,011,948...133,039,167
Ensembl chr 6:133,011,989...133,041,971 		JBrowse link
G Cyp51 cytochrome P450, family 51 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 4:30,991,693...31,010,147
Ensembl chr 4:30,991,613...31,010,450 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202 		JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 involved_in TAS
IEA 		GO_REF:0000043 UniProt
RGD		 PMID:12029625 GO_REF:0000043, RGD:1298868 NCBI chr 2:102,419,011...102,586,047
Ensembl chr 2:102,419,011...102,451,804 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase acts_upstream_of_or_within
involved_in 		ISO
IEA 		MGI:3027024 (PMID:16407971)
GO_REF:0000107
GO_REF:0000043 		RGD
Ensembl
UniProt		 PMID:16407971 GO_REF:0000043 GO_REF:0000107 NCBI chr 5:126,573,366...126,599,940
Ensembl chr 5:126,573,338...126,599,936 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:208,444,434...208,460,408
Ensembl chr 1:208,444,434...208,461,382 		JBrowse link
G Disp3 dispatched RND transporter family member 3 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:158,672,015...158,720,806
Ensembl chr 5:163,955,160...164,003,950 		JBrowse link
G Ebp EBP, cholestenol delta-isomerase involved_in ISO
IEA 		(PMID:10391219)
GO_REF:0000107
GO_REF:0000043 		RGD
Ensembl
UniProt		 PMID:10391219 GO_REF:0000043 GO_REF:0000107 NCBI chr  X:16,971,372...16,977,782
Ensembl chr  X:16,971,405...16,977,781 		JBrowse link
G ENSRNOG00000062441 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G Erlin1 ER lipid raft associated 1 involved_in IEA GO_REF:0000104
GO_REF:0000043 		UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:252,870,356...252,905,947 		JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr16:65,017,654...65,034,184
Ensembl chr16:71,721,364...71,736,503 		JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 acts_upstream_of_or_within ISO
IEA 		MGI:3769404 (PMID:22912762), (PMID:28053990)
GO_REF:0000107 		RGD
Ensembl		 PMID:22912762 PMID:28053990 GO_REF:0000107 NCBI chr 5:166,606,841...166,620,124
Ensembl chr 5:166,606,834...166,620,432 		JBrowse link
G Fabp1 fatty acid binding protein 1 acts_upstream_of_or_within ISO MGI:106926 (PMID:30910689), (PMID:38417694) RGD PMID:30910689 PMID:38417694 NCBI chr 4:104,744,302...104,753,119
Ensembl chr 4:104,744,309...104,753,113 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr15:41,588,114...41,616,168
Ensembl chr15:41,588,117...41,616,168 		JBrowse link
G Fdps farnesyl diphosphate synthase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:176,795,192...176,804,816
Ensembl chr 2:176,795,192...176,807,136 		JBrowse link
G Fdx1 ferredoxin 1 involved_in IEA
ISS
ISO 		GO_REF:0000107
GO_REF:0000043
GO_REF:0000024
(PMID:21636783) 		Ensembl
UniProt
RGD		 PMID:21636783 GO_REF:0000024 GO_REF:0000043 GO_REF:0000107 NCBI chr 8:52,268,536...52,287,344
Ensembl chr 8:61,164,839...61,183,583 		JBrowse link
G Fdxr ferredoxin reductase involved_in IEA GO_REF:0000041
GO_REF:0000043 		UniProt GO_REF:0000041 GO_REF:0000043 NCBI chr10:100,507,863...100,516,649
Ensembl chr10:101,006,849...101,015,542 		JBrowse link
G Fech ferrochelatase acts_upstream_of_or_within ISO
IEA 		MGI:1858114 (PMID:11160364)
GO_REF:0000107 		RGD
Ensembl		 PMID:11160364 GO_REF:0000107 NCBI chr18:60,215,325...60,248,525
Ensembl chr18:60,215,325...60,249,546 		JBrowse link
G Fgl1 fibrinogen-like 1 acts_upstream_of_or_within ISO MGI:5510996 (PMID:23483972) RGD PMID:23483972 NCBI chr16:57,824,127...57,854,413
Ensembl chr16:57,824,200...57,854,429 		JBrowse link
G Gba1 glucosylceramidase beta 1 involved_in ISO
IEA 		(PMID:24211208), (PMID:26724485)
GO_REF:0000117
GO_REF:0000107
GO_REF:0000041 		RGD
UniProt
Ensembl		 PMID:24211208 PMID:26724485 GO_REF:0000041 GO_REF:0000107 GO_REF:0000117 NCBI chr 2:176,902,141...176,916,015
Ensembl chr 2:176,907,154...176,916,985 		JBrowse link
G Gba2 glucosylceramidase beta 2 involved_in IEA
ISO
ISS 		GO_REF:0000041
GO_REF:0000043
(PMID:26724485)
GO_REF:0000107
GO_REF:0000024 		UniProt
RGD
Ensembl		 PMID:26724485 GO_REF:0000024 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 NCBI chr 5:62,618,176...62,630,160
Ensembl chr 5:62,618,177...62,630,308 		JBrowse link
G Hdlbp high density lipoprotein binding protein involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 9:101,395,491...101,465,446
Ensembl chr 9:101,397,305...101,465,379 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:188,564,348...188,590,872
Ensembl chr 2:188,547,767...188,592,242 		JBrowse link
G Hnf1a HNF1 homeobox A acts_upstream_of_or_within ISO
IEA 		MGI:2384427 (PMID:11279518)
GO_REF:0000107 		RGD
Ensembl		 PMID:11279518 GO_REF:0000107 NCBI chr12:47,299,171...47,333,457
Ensembl chr12:47,306,245...47,332,755 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:66,539,761...66,547,524
Ensembl chr17:66,539,763...66,547,524 		JBrowse link
G Idi2 isopentenyl-diphosphate delta isomerase 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,331,385...61,334,987 JBrowse link
G Idi2-ps1 isopentenyl-diphosphate delta isomerase 2, pseudogene 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,420,357...61,423,924 JBrowse link
G Idi2l2 isopentenyl-diphosphate delta isomerase 2 like 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,372,853...61,386,459 JBrowse link
G Idi2l3 isopentenyl-diphosphate delta isomerase 2 like 3 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,518,138...61,535,484 JBrowse link
G Il4 interleukin 4 involved_in ISO (PMID:11971948) RGD PMID:11971948 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Insig1 insulin induced gene 1 acts_upstream_of_or_within
involved_in 		ISO
IEA 		MGI:1920249 (PMID:16100574)
GO_REF:0000043 		RGD
UniProt		 PMID:16100574 GO_REF:0000043 NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:8,049,556...8,057,778 		JBrowse link
G Insig2 insulin induced gene 2 acts_upstream_of_or_within
involved_in 		ISO
IEA 		MGI:1916289 (PMID:16100574)
GO_REF:0000043
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:16100574 GO_REF:0000043 GO_REF:0000107 NCBI chr13:35,025,160...35,052,937
Ensembl chr13:35,025,164...35,047,658 		JBrowse link
G Lbr lamin B receptor involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr13:96,071,058...96,095,709
Ensembl chr13:96,071,081...96,095,709 		JBrowse link
G Lcat lecithin cholesterol acyltransferase involved_in
acts_upstream_of_or_within 		IDA
IEA
ISO 		GO_REF:0000117
(PMID:15654758), (PMID:26195816), (PMID:3458198), (PMID:4335615)
GO_REF:0000107
GO_REF:0000043
(PMID:9300780)
(PMID:10559507) 		UniProt
RGD
Ensembl		 PMID:3458198 PMID:4335615 PMID:9300780 PMID:10559507 PMID:15654758 More... GO_REF:0000043 GO_REF:0000107 GO_REF:0000117, RGD:1581789 NCBI chr19:50,744,598...50,748,064
Ensembl chr19:50,744,601...50,748,081 		JBrowse link
G Ldlr low density lipoprotein receptor acts_upstream_of_or_within
involved_in 		ISO
IEA 		MGI:1857212 (PMID:17071966)
GO_REF:0000043
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:17071966 GO_REF:0000043 GO_REF:0000107 NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675 		JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:152,239,296...152,262,290
Ensembl chr 5:152,229,505...152,262,290 		JBrowse link
G Lep leptin acts_upstream_of_or_within ISO
IEA 		MGI:88049 (PMID:15995171)
GO_REF:0000107 		RGD
Ensembl		 PMID:15995171 GO_REF:0000107 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661 		JBrowse link
G Lepr leptin receptor acts_upstream_of_or_within ISO
IEA 		MGI:88049 (PMID:15995171)
GO_REF:0000107 		RGD
Ensembl		 PMID:15995171 GO_REF:0000107 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215 		JBrowse link
G Lima1 LIM domain and actin binding 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:130,901,717...131,001,512
Ensembl chr 7:132,780,556...132,880,386 		JBrowse link
G Lipa lipase A, lysosomal acid type acts_upstream_of_or_within ISO
IEA 		MGI:2451080|MGI:5428633 (PMID:24370824), (PMID:30639734)
GO_REF:0000107 		RGD
Ensembl		 PMID:24370824 PMID:30639734 GO_REF:0000107 NCBI chr 1:241,437,524...241,470,936
Ensembl chr 1:241,437,524...241,470,740 		JBrowse link
G Lipc lipase C, hepatic type acts_upstream_of_or_within ISO
IEA 		MGI:88050 (PMID:10357838)
GO_REF:0000107 		RGD
Ensembl		 PMID:10357838 GO_REF:0000107 NCBI chr 8:80,390,470...80,516,463
Ensembl chr 8:80,390,471...80,516,285 		JBrowse link
G Lipe lipase E, hormone sensitive type involved_in IEA GO_REF:0000043
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr 1:90,093,433...90,112,117
Ensembl chr 1:90,093,433...90,112,117 		JBrowse link
G LOC102550988 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,451,920...61,457,799 JBrowse link
G LOC102551575 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,504,294...61,507,015 JBrowse link
G LOC120097764 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:61,338,622...61,349,795 JBrowse link
G LOC120099768 sulfotransferase 2A1-like involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:76,058,556...76,077,447 JBrowse link
G LOC120102490 insulin-induced gene 1 protein-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 4:67,330,399...67,331,371
Ensembl chr 4:68,297,489...68,298,247 		JBrowse link
G LOC134482631 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G LOC134482634 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G LOC134482635 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G LOC134482779 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G LOC134482866 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G LOC134484812 isopentenyl-diphosphate delta-isomerase 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G Lrp1 LDL receptor related protein 1 acts_upstream_of_or_within ISO MGI:2177650|MGI:2180880 (PMID:17920016) RGD PMID:17920016 NCBI chr 7:65,265,639...65,346,196
Ensembl chr 7:65,265,639...65,346,196 		JBrowse link
G Lrp5 LDL receptor related protein 5 acts_upstream_of_or_within ISO
IEA 		MGI:2448955 (PMID:12509515)
GO_REF:0000107 		RGD
Ensembl		 PMID:12509515 GO_REF:0000107 NCBI chr 1:210,243,499...210,346,886
Ensembl chr 1:210,243,502...210,346,822 		JBrowse link
G Mbtps1 membrane-bound transcription factor peptidase, site 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr19:64,470,245...64,521,438
Ensembl chr19:64,470,545...64,521,342 		JBrowse link
G Msmo1 methylsterol monooxygenase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr16:29,747,113...29,764,360
Ensembl chr16:29,747,137...29,764,445 		JBrowse link
G Mttp microsomal triglyceride transfer protein acts_upstream_of_or_within ISO MGI:95479 (PMID:38417694) RGD PMID:38417694 NCBI chr 2:229,286,501...229,327,650
Ensembl chr 2:229,286,501...229,327,650 		JBrowse link
G Mvd mevalonate diphosphate decarboxylase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr19:67,404,911...67,414,974
Ensembl chr19:67,404,911...67,422,366 		JBrowse link
G Mvk mevalonate kinase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr12:47,802,002...47,819,503
Ensembl chr12:47,802,002...47,819,503 		JBrowse link
G Nfe2l1 NFE2 like bZIP transcription factor 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:82,296,824...82,309,472
Ensembl chr10:82,292,508...82,309,375 		JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr18:3,654,237...3,699,853
Ensembl chr18:3,654,237...3,699,800 		JBrowse link
G Npc1l1 NPC1 like intracellular cholesterol transporter 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:81,071,448...81,091,113
Ensembl chr14:85,285,390...85,305,050 		JBrowse link
G Nsdhl NAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL involved_in
acts_upstream_of_or_within 		IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000117
GO_REF:0000107
GO_REF:0000043
MGI:1857776 (PMID:10369263) 		GO_Central
UniProt
Ensembl
RGD		 PMID:10369263 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 GO_REF:0000117 NCBI chr  X:155,817,301...155,848,224
Ensembl chr  X:155,817,340...155,848,220 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 acts_upstream_of_or_within
involved_in 		ISO
IEA 		(PMID:17242417)
GO_REF:0000107
GO_REF:0000043 		RGD
Ensembl
UniProt		 PMID:17242417 GO_REF:0000043 GO_REF:0000107 NCBI chr 5:126,440,102...126,462,507
Ensembl chr 5:126,440,102...126,462,507 		JBrowse link
G Pctp phosphatidylcholine transfer protein acts_upstream_of_or_within ISO MGI:2673156 (PMID:15845870) RGD PMID:15845870 NCBI chr10:75,305,999...75,351,919
Ensembl chr10:75,305,999...75,326,432 		JBrowse link
G Pip4p1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 involved_in ISO
IEA
ISS 		(PMID:25035345)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:25035345 GO_REF:0000024 GO_REF:0000107 NCBI chr15:24,146,854...24,150,739
Ensembl chr15:26,620,401...26,624,246 		JBrowse link
G Pmp22 peripheral myelin protein 22 acts_upstream_of_or_within ISO MGI:3614822 (PMID:25429154) RGD PMID:25429154 NCBI chr10:48,294,932...48,324,941
Ensembl chr10:48,297,437...48,324,940 		JBrowse link
G Pmvk phosphomevalonate kinase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:177,174,344...177,184,076
Ensembl chr 2:177,174,335...177,184,080 		JBrowse link
G Pon1 paraoxonase 1 acts_upstream_of_or_within ISO
IEA 		MGI:2148702 (PMID:9685159)
GO_REF:0000107 		RGD
Ensembl		 PMID:9685159 GO_REF:0000107 NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:34,261,289...34,287,924 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:55,967,351...56,003,450 		JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:125,042,179...125,108,324 		JBrowse link
G Rusc1 RUN and SH3 domain containing 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:174,487,921...174,497,266
Ensembl chr 2:176,785,711...176,794,178 		JBrowse link
G Scap SREBF chaperone involved_in
acts_upstream_of_or_within 		ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
GO_REF:0000043
(PMID:11358865) 		UniProt
Ensembl
RGD		 PMID:11358865 GO_REF:0000024 GO_REF:0000043 GO_REF:0000107 NCBI chr 8:119,184,366...119,239,086
Ensembl chr 8:119,184,438...119,239,075 		JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 acts_upstream_of_or_within ISO
IEA 		(PMID:22383528)
GO_REF:0000107 		RGD
Ensembl		 PMID:22383528 GO_REF:0000107 NCBI chr 1:169,304,772...169,308,615
Ensembl chr 1:169,304,708...169,308,614 		JBrowse link
G Soat1 sterol O-acyltransferase 1 involved_in
acts_upstream_of_or_within 		TAS
ISO
IEA
IBA
ISS 		(PMID:16647063), (PMID:18971559), (PMID:8407899)
GO_REF:0000107
GO_REF:0000043
(PMID:15845870)
GO_REF:0000033
(PMID:9756919)
GO_REF:0000024 		RGD
Ensembl
UniProt
GO_Central		 PMID:8407899 PMID:9756919 PMID:15845870 PMID:16647063 PMID:18971559 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107, RGD:730254 NCBI chr13:71,105,178...71,147,776
Ensembl chr13:71,105,178...71,147,672 		JBrowse link
G Soat2 sterol O-acyltransferase 2 involved_in
acts_upstream_of_or_within 		IDA
IEA
ISO
IBA 		GO_REF:0000043
GO_REF:0000107
(PMID:9756919)
GO_REF:0000033
(PMID:11294643), (PMID:16647063) 		UniProt
Ensembl
RGD
GO_Central		 PMID:9756919 PMID:11294643 PMID:16647063 PMID:12217884 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107, RGD:625687 NCBI chr 7:133,281,818...133,294,915
Ensembl chr 7:135,160,402...135,173,513 		JBrowse link
G Sqle squalene epoxidase IMP RGD PMID:9300786 RGD:1625701 NCBI chr 7:92,758,175...92,773,049
Ensembl chr 7:92,757,409...92,773,050 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 involved_in IMP
IEA 		GO_REF:0000043 UniProt
RGD		 PMID:18071061 GO_REF:0000043, RGD:1643359 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164 		JBrowse link
G Srebf1_v2 sterol regulatory element binding factor 1, variant 2 IMP RGD PMID:18071061 RGD:1643359
G Srebf2 sterol regulatory element binding transcription factor 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:115,542,774...115,600,945
Ensembl chr 7:115,543,290...115,600,943 		JBrowse link
G Star steroidogenic acute regulatory protein involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447 		JBrowse link
G Sult1c3 sulfotransferase family 1C member 3 involved_in ISO (PMID:28992322) RGD PMID:28992322 NCBI chr 9:7,548,839...7,594,299
Ensembl chr 9:7,548,622...7,594,295 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 involved_in ISO
ISS 		(PMID:19589875)
GO_REF:0000024 		RGD
UniProt		 PMID:19589875 GO_REF:0000024 NCBI chr 1:84,582,011...84,639,001 JBrowse link
G Sult2b1 sulfotransferase family 2B member 1 involved_in ISO
IEA
ISS 		(PMID:28575648)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:28575648 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:96,200,155...96,261,295
Ensembl chr 1:105,336,614...105,397,744 		JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:212,785,217...212,789,572
Ensembl chr 1:212,785,217...212,789,557 		JBrowse link
G Tnfsf4 TNF superfamily member 4 acts_upstream_of_or_within ISO
IEA 		(PMID:3473481)
GO_REF:0000107 		RGD
Ensembl		 PMID:3473481 GO_REF:0000107 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:76,256,654...76,280,133 		JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan involved_in ISS
ISO 		GO_REF:0000024
(PMID:31391339) 		UniProt
RGD		 PMID:31391339 GO_REF:0000024 NCBI chr 1:162,071,459...162,082,972
Ensembl chr 1:162,064,126...162,089,272 		JBrowse link
G Vldlr very low density lipoprotein receptor involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:234,239,769...234,272,150
Ensembl chr 1:234,240,121...234,272,154 		JBrowse link
isocitrate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 4933405O20Rikl RIKEN cDNA 4933405O20 gene like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:100,300,241...100,301,711 JBrowse link
G Aco2 aconitase 2 IDA RGD PMID:14674759 RGD:2306852 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:115,265,791...115,308,892 		JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 involved_in IDA
IEA
IBA
ISO
ISS 		GO_REF:0000107
GO_REF:0000033
GO_REF:0000002
(PMID:10521434), (PMID:19935646), (PMID:20171178)
GO_REF:0000024 		Ensembl
GO_Central
InterPro
RGD
UniProt		 PMID:10521434 PMID:19935646 PMID:20171178 PMID:17447164 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:1624966 NCBI chr 9:74,027,887...74,057,442
Ensembl chr 9:74,027,892...74,049,555 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 involved_in ISS
IEA 		GO_REF:0000024
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000024 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:143,439,323...143,467,248 		JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:63,867,882...63,887,223
Ensembl chr 8:63,867,820...63,887,223 		JBrowse link
G Idh3b isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:117,481,845...117,486,909
Ensembl chr 3:137,934,697...137,940,107 		JBrowse link
G Idh3g isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma involved_in ISO
IBA
ISS 		(PMID:2605193)
GO_REF:0000033
GO_REF:0000024 		RGD
GO_Central
UniProt		 PMID:2605193 GO_REF:0000024 GO_REF:0000033 NCBI chr  X:156,666,573...156,675,482
Ensembl chr  X:156,666,577...156,675,799 		JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in IDA
ISO
IEA 		(PMID:1917954)
GO_REF:0000107 		RGD
Ensembl		 PMID:1917954 PMID:9225228 GO_REF:0000107, RGD:10059686 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855 		JBrowse link
G Chlsn cholesin involved_in ISO (PMID:38503280) RGD PMID:38503280 NCBI chr12:20,298,968...20,402,890
Ensembl chr12:20,388,520...20,402,922 		JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO
IEA 		(PMID:24217618)
GO_REF:0000117
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:24217618 GO_REF:0000107 GO_REF:0000117 NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:252,870,356...252,905,947 		JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO
IEA 		(PMID:24217618)
GO_REF:0000117 		RGD
UniProt		 PMID:24217618 GO_REF:0000117 NCBI chr16:65,017,654...65,034,184
Ensembl chr16:71,721,364...71,736,503 		JBrowse link
G Idi2 isopentenyl-diphosphate delta isomerase 2 acts_upstream_of_or_within ISO (PMID:17202134) RGD PMID:17202134 NCBI chr17:61,331,385...61,334,987 JBrowse link
G Insig1 insulin induced gene 1 involved_in ISO (PMID:26311497) RGD PMID:26311497 NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:8,049,556...8,057,778 		JBrowse link
G Marchf6 membrane associated ring-CH-type finger 6 involved_in ISO (PMID:32755570) RGD PMID:32755570 NCBI chr 2:84,166,570...84,243,817
Ensembl chr 2:84,166,570...84,243,792 		JBrowse link
G Mir185 microRNA 185 acts_upstream_of ISO RNAcentral:URS00002367FA_9606|RNAcentral:URS00004176D4_9606 (PMID:23951060), (PMID:24296663) RGD PMID:23951060 PMID:24296663 NCBI chr11:82,664,716...82,664,795
Ensembl chr11:96,169,028...96,169,107 		JBrowse link
G Mir342 microRNA 342 acts_upstream_of ISO (PMID:23951060) RGD PMID:23951060 NCBI chr 6:133,329,655...133,329,753
Ensembl chr 6:133,329,655...133,329,753 		JBrowse link
G Mir98 microRNA 98 involved_in ISO (PMID:30195495) RGD PMID:30195495 NCBI chr  X:24,460,648...24,460,755
Ensembl chr  X:24,460,648...24,460,755 		JBrowse link
negative regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ch25h cholesterol 25-hydroxylase involved_in ISO (PMID:29033131) RGD PMID:29033131 NCBI chr 1:241,428,048...241,429,366
Ensembl chr 1:241,331,619...241,431,190 		JBrowse link
G Mir27a microRNA 27a involved_in ISO (PMID:24608080) RGD PMID:24608080 NCBI chr19:40,859,603...40,859,689 JBrowse link
G Mir27b microRNA 27b involved_in ISO (PMID:24608080) RGD PMID:24608080 NCBI chr17:1,819,147...1,819,243 JBrowse link
positive regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO
IEA 		(PMID:17916878)
GO_REF:0000117
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:17916878 GO_REF:0000107 GO_REF:0000117 NCBI chr20:9,128,056...9,184,312
Ensembl chr20:9,127,803...9,186,563 		JBrowse link
G Abcg4 ATP binding cassette subfamily G member 4 involved_in IEA
ISO 		GO_REF:0000107
GO_REF:0000117
(PMID:17916878) 		Ensembl
UniProt
RGD		 PMID:17916878 GO_REF:0000107 GO_REF:0000117 NCBI chr 8:44,611,187...44,629,818
Ensembl chr 8:53,508,005...53,523,571 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 acts_upstream_of_or_within ISO (PMID:12177166) RGD PMID:12177166 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Chlsn cholesin acts_upstream_of_or_within ISO (PMID:38503280) RGD PMID:38503280 NCBI chr12:20,298,968...20,402,890
Ensembl chr12:20,388,520...20,402,922 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 involved_in IDA PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202 		JBrowse link
G Fdps farnesyl diphosphate synthase IMP RGD PMID:18637708 RGD:2316295 NCBI chr 2:176,795,192...176,804,816
Ensembl chr 2:176,795,192...176,807,136 		JBrowse link
G Fgf1 fibroblast growth factor 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:19229075) 		UniProt
RGD		 PMID:19229075 GO_REF:0000024 NCBI chr18:30,937,670...31,023,786
Ensembl chr18:30,939,870...30,961,393 		JBrowse link
G Gnai1 G protein subunit alpha i1 involved_in
acts_upstream_of_or_within 		ISO (PMID:38503280) RGD PMID:38503280 NCBI chr 4:17,706,061...17,790,176
Ensembl chr 4:17,706,025...17,789,198 		JBrowse link
G Gpr146 G protein-coupled receptor 146 acts_upstream_of_or_within ISO (PMID:38503280) RGD PMID:38503280 NCBI chr12:20,365,790...20,381,122
Ensembl chr12:20,364,269...20,381,345 		JBrowse link
G Insig1 insulin induced gene 1 acts_upstream_of_or_within ISO (PMID:11163209), (PMID:12177166) RGD PMID:11163209 PMID:12177166 NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:8,049,556...8,057,778 		JBrowse link
G Insig2 insulin induced gene 2 acts_upstream_of_or_within ISO (PMID:12177166) RGD PMID:12177166 NCBI chr13:35,025,160...35,052,937
Ensembl chr13:35,025,164...35,047,658 		JBrowse link
G Kpnb1 karyopherin subunit beta 1 acts_upstream_of_or_within ISO (PMID:12177166) RGD PMID:12177166 NCBI chr10:82,642,082...82,670,856
Ensembl chr10:82,642,082...82,670,856 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in
acts_upstream_of_or_within 		IEA
ISO 		GO_REF:0000107
(PMID:38503280) 		Ensembl
RGD		 PMID:38503280 GO_REF:0000107 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mbtps1 membrane-bound transcription factor peptidase, site 1 acts_upstream_of_or_within ISO (PMID:12177166) RGD PMID:12177166 NCBI chr19:64,470,245...64,521,438
Ensembl chr19:64,470,545...64,521,342 		JBrowse link
G Mbtps2 membrane-bound transcription factor peptidase, site 2 involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:11163209)
(PMID:12177166)
GO_REF:0000107 		RGD
Ensembl		 PMID:11163209 PMID:12177166 GO_REF:0000107 NCBI chr  X:41,225,956...41,290,030
Ensembl chr  X:41,254,335...41,277,701 		JBrowse link
G Mir182 microRNA 182 involved_in ISO RNAcentral:URS000016FF9C_9606 (PMID:23823476) RGD PMID:23823476 NCBI chr 4:59,752,246...59,752,307 JBrowse link
G Mir96 microRNA 96 involved_in
acts_upstream_of 		ISO RNAcentral:URS00001CC379_9606 (PMID:23823476)
(PMID:30460077) 		RGD PMID:23823476 PMID:30460077 NCBI chr 4:59,755,841...59,755,946 JBrowse link
G Npy1r neuropeptide Y receptor Y1 IMP RGD PMID:32976883 RGD:405096663 NCBI chr16:27,804,416...27,814,070
Ensembl chr16:27,804,416...27,813,387 		JBrowse link
G Paqr3 progestin and adipoQ receptor family member 3 involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:26311497)
(PMID:11163209), (PMID:12177166)
GO_REF:0000107 		RGD
Ensembl		 PMID:11163209 PMID:12177166 PMID:26311497 GO_REF:0000107 NCBI chr14:12,766,539...12,796,461
Ensembl chr14:12,766,570...12,790,001 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 acts_upstream_of_or_within ISO (PMID:12177166) RGD PMID:12177166 NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in
acts_upstream_of_or_within 		IEA
ISO 		GO_REF:0000107
(PMID:38503280) 		Ensembl
RGD		 PMID:38503280 GO_REF:0000107 NCBI chr19:41,059,843...41,083,189
Ensembl chr19:41,059,843...41,086,494 		JBrowse link
G Qki QKI, KH domain containing RNA binding involved_in ISO (PMID:33942715) RGD PMID:33942715 NCBI chr 1:52,935,357...53,047,338
Ensembl chr 1:52,935,382...53,047,337 		JBrowse link
G Scap SREBF chaperone involved_in ISO
IEA 		(PMID:32322062)
GO_REF:0000107 		RGD
Ensembl		 PMID:32322062 GO_REF:0000107 NCBI chr 8:119,184,366...119,239,086
Ensembl chr 8:119,184,438...119,239,075 		JBrowse link
G Scp2 sterol carrier protein 2 IDA RGD PMID:2554812 RGD:9850260 NCBI chr 5:128,035,714...128,110,015
Ensembl chr 5:128,008,125...128,110,043 		JBrowse link
G Sec14l2 SEC14-like lipid binding 2 IDA RGD PMID:11226224 RGD:727312 NCBI chr14:83,197,384...83,222,059
Ensembl chr14:83,197,387...83,217,317 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within 		ISO
IEA
ISS 		(PMID:12177166)
GO_REF:0000107
(PMID:8833906), (PMID:9062341)
MGI:2177958|MGI:2177959 (PMID:16046411), (PMID:9329978)
GO_REF:0000024
(PMID:32322062) 		RGD
Ensembl
UniProt		 PMID:8833906 PMID:9062341 PMID:9329978 PMID:12177166 PMID:16046411 More... GO_REF:0000024 GO_REF:0000107 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 involved_in IEA
ISO
ISS 		GO_REF:0000107
(PMID:33942715), (PMID:34021134)
(PMID:12177166), (PMID:38503280)
GO_REF:0000024
(PMID:32322062) 		Ensembl
RGD
UniProt		 PMID:12177166 PMID:32322062 PMID:33942715 PMID:34021134 PMID:38503280 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:115,542,774...115,600,945
Ensembl chr 7:115,543,290...115,600,943 		JBrowse link
G Yy2 YY2 transcription factor involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr  X:37,438,425...37,442,047
Ensembl chr  X:41,254,335...41,277,701 		JBrowse link
positive regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen acts_upstream_of ISO
IEA 		(PMID:18971559)
GO_REF:0000107 		RGD
Ensembl		 PMID:18971559 GO_REF:0000107 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a acts_upstream_of ISO (PMID:18971559) RGD PMID:18971559 NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660 		JBrowse link
G Apoa1 apolipoprotein A1 involved_in ISO
IEA 		(PMID:4335615)
GO_REF:0000107 		RGD
Ensembl		 PMID:4335615 GO_REF:0000107 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729 		JBrowse link
G Apoe apolipoprotein E involved_in ISO
IEA 		(PMID:15654758)
GO_REF:0000107 		RGD
Ensembl		 PMID:15654758 GO_REF:0000107 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855 		JBrowse link
G Ces1d carboxylesterase 1D involved_in ISO (PMID:16971496) RGD PMID:16971496 NCBI chr19:30,046,494...30,085,039
Ensembl chr19:30,046,449...30,085,449 		JBrowse link
G Stard4 StAR-related lipid transfer domain containing 4 involved_in ISO
IEA 		(PMID:18403318)
GO_REF:0000107 		RGD
Ensembl		 PMID:18403318 GO_REF:0000107 NCBI chr18:24,814,683...24,830,024
Ensembl chr18:25,091,255...25,104,172 		JBrowse link
regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 NOT|involved_in ISO (PMID:21810484) RGD PMID:21810484 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:28,642,758...28,662,681 		JBrowse link
G Apob apolipoprotein B acts_upstream_of_or_within ISO
IEA 		MGI:2183298 (PMID:16455790)
GO_REF:0000107 		RGD
Ensembl		 PMID:16455790 GO_REF:0000107 NCBI chr 6:36,563,704...36,603,300
Ensembl chr 6:36,563,704...36,611,814 		JBrowse link
G Aqp8 aquaporin 8 involved_in IEA
ISO
ISS 		GO_REF:0000107
(PMID:30579780)
GO_REF:0000024 		Ensembl
RGD
UniProt		 PMID:30579780 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:187,424,417...187,430,242 		JBrowse link
G Chlsn cholesin acts_upstream_of_or_within ISO (PMID:38503280) RGD PMID:38503280 NCBI chr12:20,298,968...20,402,890
Ensembl chr12:20,388,520...20,402,922 		JBrowse link
G Cyp51 cytochrome P450, family 51 TAS RGD PMID:7665087 RGD:1298863 NCBI chr 4:30,991,693...31,010,147
Ensembl chr 4:30,991,613...31,010,450 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase IDA RGD PMID:10329655 RGD:632010 NCBI chr 1:208,444,434...208,460,408
Ensembl chr 1:208,444,434...208,461,382 		JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO
IEA 		(PMID:24217618)
GO_REF:0000107 		RGD
Ensembl		 PMID:24217618 GO_REF:0000107 NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:252,870,356...252,905,947 		JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr16:65,017,654...65,034,184
Ensembl chr16:71,721,364...71,736,503 		JBrowse link
G Gpr146 G protein-coupled receptor 146 involved_in ISO
IEA 		(PMID:38503280)
GO_REF:0000107 		RGD
Ensembl		 PMID:38503280 GO_REF:0000107 NCBI chr12:20,365,790...20,381,122
Ensembl chr12:20,364,269...20,381,345 		JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 involved_in ISS
ISO 		GO_REF:0000024
(PMID:29395055) 		UniProt
RGD		 PMID:29395055 GO_REF:0000024 NCBI chr 4:159,154,690...159,196,176
Ensembl chr 4:159,154,158...159,196,358 		JBrowse link
G Mvk mevalonate kinase NAS RGD PMID:2158094 RGD:728935 NCBI chr12:47,802,002...47,819,503
Ensembl chr12:47,802,002...47,819,503 		JBrowse link
G Pex2 peroxisomal biogenesis factor 2 acts_upstream_of_or_within ISO MGI:2180128 (PMID:14673138) RGD PMID:14673138 NCBI chr 2:97,957,479...97,973,767
Ensembl chr 2:97,948,443...97,981,092 		JBrowse link
G Scap SREBF chaperone involved_in
acts_upstream_of_or_within 		IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
MGI:2148743|MGI:2180899 (PMID:16054043) 		GO_Central
Ensembl
RGD		 PMID:16054043 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:119,184,366...119,239,086
Ensembl chr 8:119,184,438...119,239,075 		JBrowse link
regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO
IEA 		(PMID:16556852)
GO_REF:0000107 		RGD
Ensembl		 PMID:16556852 GO_REF:0000107 NCBI chr20:9,128,056...9,184,312
Ensembl chr20:9,127,803...9,186,563 		JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain involved_in ISO (PMID:15639194) RGD PMID:15639194 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:75,783,689...75,822,164 		JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain involved_in IEA
ISO 		GO_REF:0000107
(PMID:15639194) 		Ensembl
RGD		 PMID:15639194 GO_REF:0000107 NCBI chr10:55,231,558...55,236,786
Ensembl chr10:55,231,440...55,236,750 		JBrowse link
G Apoe apolipoprotein E involved_in ISO
IEA 		UniProtKB:P35951 (PMID:24412220)
GO_REF:0000117
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:24412220 GO_REF:0000107 GO_REF:0000117 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855 		JBrowse link
G Arv1 ARV1 homolog, fatty acid homeostasis modulator involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:20663892)
GO_REF:0000107 		RGD
Ensembl		 PMID:20663892 GO_REF:0000107 NCBI chr19:69,589,728...69,601,547
Ensembl chr19:69,589,328...69,601,537 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 IMP RGD PMID:17526931 RGD:10400884 NCBI chr 1:162,866,237...162,896,655
Ensembl chr 1:162,866,237...162,896,566 		JBrowse link
G Dgkq diacylglycerol kinase, theta involved_in ISO (PMID:24369117) RGD PMID:24369117 NCBI chr14:1,059,125...1,073,131
Ensembl chr14:1,203,565...1,218,024 		JBrowse link
G Ephx2 epoxide hydrolase 2 involved_in ISO
IEA 		(PMID:18974052)
GO_REF:0000107 		RGD
Ensembl		 PMID:18974052 GO_REF:0000107 NCBI chr15:44,465,447...44,503,157
Ensembl chr15:44,465,448...44,503,160 		JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 involved_in IEA
ISO
ISS 		GO_REF:0000107
(PMID:26049045)
GO_REF:0000024 		Ensembl
RGD
UniProt		 PMID:26049045 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:187,885,741...187,938,468
Ensembl chr 2:187,910,964...187,938,464 		JBrowse link
G Gnb3 G protein subunit beta 3 involved_in ISO
IEA 		UniProtKB:Q61011 (PMID:29206867)
GO_REF:0000107 		RGD
Ensembl		 PMID:29206867 GO_REF:0000107 NCBI chr 4:157,639,468...157,645,171
Ensembl chr 4:159,325,742...159,331,445 		JBrowse link
G Ldlr low density lipoprotein receptor involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:P02649 (PMID:24412220) 		Ensembl
RGD		 PMID:24412220 GO_REF:0000107 NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675 		JBrowse link
G Lmf1 lipase maturation factor 1 acts_upstream_of_or_within ISO
IEA 		MGI:1856820 (PMID:6857276)
GO_REF:0000107 		RGD
Ensembl		 PMID:6857276 GO_REF:0000107 NCBI chr10:14,597,726...14,684,071
Ensembl chr10:15,098,138...15,188,664 		JBrowse link
G Serpina12 serpin family A member 12 acts_upstream_of_or_within ISO
IEA 		MGI:5568548 (PMID:22837305)
GO_REF:0000107 		RGD
Ensembl		 PMID:22837305 GO_REF:0000107 NCBI chr 6:122,952,552...122,967,271
Ensembl chr 6:128,717,334...128,732,049 		JBrowse link
G Thrb thyroid hormone receptor beta IMP RGD PMID:17878314 RGD:2315101 NCBI chr15:10,115,954...10,465,231
Ensembl chr15:10,115,954...10,313,680 		JBrowse link
G Ttc39b tetratricopeptide repeat domain 39B involved_in ISS
ISO
IBA
IEA 		GO_REF:0000024
(PMID:27383786)
GO_REF:0000033
GO_REF:0000107 		UniProt
RGD
GO_Central
Ensembl		 PMID:27383786 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:102,649,259...102,754,092
Ensembl chr 5:102,655,322...102,782,162 		JBrowse link
G Ttc39d tetratricopeptide repeat domain 39D involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:14,802,753...14,811,516
Ensembl chr 6:20,554,991...20,563,753 		JBrowse link
vitamin D3 metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO MGI:1857079 (PMID:28798354) RGD PMID:28798354 NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:22,518,069...22,583,044 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO
IEA 		MGI:95525 (PMID:24259513)
GO_REF:0000107 		RGD
Ensembl		 PMID:24259513 GO_REF:0000107 NCBI chr16:73,194,631...73,249,855
Ensembl chr16:73,194,631...73,249,855 		JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 acts_upstream_of_or_within ISO MGI:95522 (PMID:24259513) RGD PMID:24259513 NCBI chr17:9,466,686...9,481,423
Ensembl chr17:9,466,692...9,481,389 		JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 involved_in ISO (PMID:23756265) RGD PMID:23756265 NCBI chr 9:96,239,019...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Ugt1a3 UDP glycosyltransferase 1 family, polypeptide A3 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 9:88,780,328...88,808,465
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 involved_in ISO (PMID:18177842), (PMID:24641623) RGD PMID:18177842 PMID:24641623 NCBI chr 9:96,210,053...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20668
    cellular process 19605
      metabolic process 12252
        small molecule metabolic process 1977
          alcohol metabolic process 404
            secondary alcohol metabolic process 193
              (17Z)-protosta-17(20),24-dien-3beta-ol metabolic process + 0
              6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde 0
              acetoin metabolic process + 0
              asperfuranone metabolic process + 0
              butanediol metabolic process + 0
              cholesterol metabolic process + 176
              cyclohexanol metabolic process + 0
              ecdysone metabolic process + 0
              ergosterol metabolic process + 0
              isocitrate metabolic process 7
              menthol metabolic process + 0
              propan-2-ol metabolic process + 0
              secondary alcohol biosynthetic process + 88
              vitamin D3 metabolic process + 11
              zymosterol metabolic process + 0
paths to the root