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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of large conductance calcium-activated potassium channel activity
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Accession:GO:1902607 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of large conductance calcium-activated potassium channel activity.
Synonyms:exact_synonym: down regulation of BK KCa channels;   down regulation of BK calcium-activated potassium channel activity;   down regulation of large conductance KCa channels;   down regulation of large conductance calcium-activated potassium channel activity;   downregulation of BK KCa channels;   downregulation of BK calcium-activated potassium channel activity;   downregulation of large conductance KCa channels;   downregulation of large conductance calcium-activated potassium channel activity;   negative regulation of BK KCa channels;   negative regulation of BK calcium-activated potassium channel activity;   negative regulation of large conductance KCa channels
 narrow_synonym: inhibition of BK KCa channels;   inhibition of BK calcium-activated potassium channel activity;   inhibition of large conductance KCa channels;   inhibition of large conductance calcium-activated potassium channel activity
 related_synonym: down regulation of BK channel activity;   downregulation of BK channel activity;   inhibition of BK channel activity;   negative regulation of BK channel activity


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negative regulation of large conductance calcium-activated potassium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crbn cereblon involved_in ISO (MGI:6150698|PMID:29530986) RGD PMID:29530986 MGI:6150698 NCBI chr 4:138,864,910...138,885,786
Ensembl chr 4:138,866,761...138,885,556
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    negative regulation of biological process 5621
      negative regulation of transport 530
        negative regulation of transporter activity 91
          negative regulation of ion transmembrane transporter activity 82
            negative regulation of potassium ion transmembrane transporter activity 23
              negative regulation of large conductance calcium-activated potassium channel activity 1
Path 2
Term Annotations click to browse term
  biological_process 19491
    localization 6443
      establishment of localization 4862
        transport 4698
          ion transport 1637
            cation transport 1258
              metal ion transport 940
                potassium ion transport 253
                  regulation of potassium ion transport 115
                    regulation of potassium ion transmembrane transport 92
                      regulation of potassium ion transmembrane transporter activity 65
                        negative regulation of potassium ion transmembrane transporter activity 23
                          negative regulation of large conductance calcium-activated potassium channel activity 1
paths to the root