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ONTOLOGY REPORT - ANNOTATIONS


Term:endoribonuclease complex
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Accession:GO:1902555 term browser browse the term
Definition:A protein complex which is capable of endoribonuclease activity.
Comment:An example is IRE1 in S. cerevisiae (UniProt ID P32361) in PMID:18191223 (inferred from direct assay).
Synonyms:related_synonym: Ire1 complex dimer;   Ire1 complex homodimer;   Ire1 complex homooligomer


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Las1 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Las1l LAS1-like, ribosome biogenesis factor IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:65,081,591...65,102,344
Ensembl chr  X:65,081,591...65,102,380
JBrowse link
microprocessor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgcr8 DGCR8 microprocessor complex subunit ISO
IBA
(PMID:15574589)
PMID:21873635
RGD PMID:15574589, PMID:21873635 RGD:13792537 NCBI chr11:86,852,682...86,885,233
Ensembl chr11:86,852,711...86,885,224
JBrowse link
G Drosha drosha ribonuclease III ISO (PMID:15574589) RGD PMID:15574589 NCBI chr 2:62,887,267...63,000,307
Ensembl chr 2:62,887,267...62,999,572
JBrowse link
mitochondrial ribonuclease P complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 IEA
ISO
ISS
GO_REF:0000107
(PMID:25925575), (PMID:28888424)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:25925575, PMID:28888424 GO_REF:0000024, GO_REF:0000107 NCBI chr  X:21,696,796...21,699,241
Ensembl chr  X:21,696,772...21,699,241
JBrowse link
G Prorp protein only RNase P catalytic subunit ISO
ISS
(PMID:25953853)
GO_REF:0000024
RGD
UniProt
PMID:25953853 GO_REF:0000024 NCBI chr 6:76,079,880...76,171,298
Ensembl chr 6:76,079,880...76,171,296
JBrowse link
G Trmt10c tRNA methyltransferase 10C, mitochondrial RNase P subunit IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:47,047,342...47,052,420
Ensembl chr11:47,047,342...47,052,418
JBrowse link
multimeric ribonuclease P complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pop1 POP1 homolog, ribonuclease P/MRP subunit ISO (PMID:16723659), (PMID:30454648) RGD PMID:16723659, PMID:30454648 NCBI chr 7:73,270,403...73,298,209
Ensembl chr 7:73,270,455...73,298,239
JBrowse link
G Pop4 POP4 homolog, ribonuclease P/MRP subunit ISO
ISS
(PMID:16723659), (PMID:30454648)
GO_REF:0000024
RGD
UniProt
PMID:16723659, PMID:30454648 GO_REF:0000024 NCBI chr 1:94,661,127...94,669,461
Ensembl chr 1:94,661,128...94,669,461
JBrowse link
G Pop5 POP5 homolog, ribonuclease P/MRP subunit ISO (PMID:16723659), (PMID:30454648) RGD PMID:16723659, PMID:30454648 NCBI chr12:47,138,346...47,143,152
Ensembl chr12:47,138,346...47,142,852
JBrowse link
G Pop7 POP7 homolog, ribonuclease P/MRP subunit ISO (PMID:16723659), (PMID:30454648) RGD PMID:16723659, PMID:30454648 NCBI chr12:22,259,713...22,260,754
Ensembl chr12:22,259,713...22,260,754
JBrowse link
G Rpp14 ribonuclease P/MRP subunit p14 ISO (PMID:16723659), (PMID:30454648) RGD PMID:16723659, PMID:30454648 NCBI chr15:18,625,963...18,636,157
Ensembl chr15:18,625,964...18,632,536
JBrowse link
G Rpp21 ribonuclease P/MRP subunit p21 ISO (PMID:16723659), (PMID:30454648) RGD PMID:16723659, PMID:30454648 NCBI chr20:2,515,541...2,517,471
Ensembl chr20:2,515,520...2,517,498
JBrowse link
G Rpp25 ribonuclease P and MRP subunit p25 ISO
ISS
(PMID:16723659), (PMID:30454648)
GO_REF:0000024
RGD
UniProt
PMID:16723659, PMID:30454648 GO_REF:0000024 NCBI chr 8:62,283,336...62,284,716
Ensembl chr 8:62,283,336...62,284,716
JBrowse link
G Rpp30 ribonuclease P/MRP subunit p30 ISO (PMID:16723659), (PMID:30454648) RGD PMID:16723659, PMID:30454648 NCBI chr 1:254,697,247...254,720,093
Ensembl chr 1:254,697,247...254,720,087
JBrowse link
G Rpp38 ribonuclease P/MRP subunit p38 ISO
IBA
(PMID:30454648)
PMID:21873635
RGD PMID:30454648, PMID:21873635 RGD:13792537 NCBI chr17:78,915,450...78,919,144
Ensembl chr17:78,915,604...78,919,143
JBrowse link
G Rpp40 ribonuclease P/MRP subunit p40 ISO
IBA
ISS
(PMID:30454648)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:30454648, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr17:29,638,647...29,647,709
Ensembl chr17:29,638,677...29,647,763
JBrowse link
nucleolar ribonuclease P complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pop1 POP1 homolog, ribonuclease P/MRP subunit ISO
IBA
(PMID:8918471)
PMID:21873635
RGD PMID:8918471, PMID:21873635 RGD:13792537 NCBI chr 7:73,270,403...73,298,209
Ensembl chr 7:73,270,455...73,298,239
JBrowse link
G Pop5 POP5 homolog, ribonuclease P/MRP subunit ISO
IBA
(MGI:MGI:2149119|PMID:11413139)
PMID:21873635
RGD PMID:11413139, PMID:21873635 MGI:MGI:2149119, RGD:13792537 NCBI chr12:47,138,346...47,143,152
Ensembl chr12:47,138,346...47,142,852
JBrowse link
G Rpp21 ribonuclease P/MRP subunit p21 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:2,515,541...2,517,471
Ensembl chr20:2,515,520...2,517,498
JBrowse link
G Rpp30 ribonuclease P/MRP subunit p30 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:254,697,247...254,720,093
Ensembl chr 1:254,697,247...254,720,087
JBrowse link
ribonuclease P complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pop4 POP4 homolog, ribonuclease P/MRP subunit IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:94,661,127...94,669,461
Ensembl chr 1:94,661,128...94,669,461
JBrowse link
RISC-loading complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ago1 argonaute RISC component 1 ISO (PMID:19966796) RGD PMID:19966796 NCBI chr 5:144,444,390...144,479,430
Ensembl chr 5:144,448,792...144,479,306
JBrowse link
G Ago2 argonaute RISC catalytic component 2 ISO
ISS
IEA
(MGI:MGI:5616320|PMID:16357216)
(PMID:15973356), (PMID:17531811), (PMID:18178619), (PMID:19820710), (PMID:19966796), (PMID:23661684)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:15973356, PMID:16357216, PMID:17531811, PMID:18178619, PMID:19820710, PMID:19966796, PMID:23661684 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5616320 NCBI chr 7:114,339,607...114,377,277
Ensembl chr 7:114,339,434...114,380,613
JBrowse link
G Ago3 argonaute RISC catalytic component 3 ISO (PMID:19966796) RGD PMID:19966796 NCBI chr 5:144,355,792...144,436,509
Ensembl chr 5:144,364,269...144,436,509
JBrowse link
G Ago4 argonaute RISC component 4 ISO (PMID:19966796) RGD PMID:19966796 NCBI chr 5:144,501,875...144,557,165
Ensembl chr 5:144,504,938...144,556,889
JBrowse link
G Dhx9 DExH-box helicase 9 ISO (PMID:17531811) RGD PMID:17531811 NCBI chr13:70,885,503...70,922,278
Ensembl chr13:70,885,504...70,922,245
JBrowse link
G Dicer1 dicer 1 ribonuclease III ISO (PMID:15973356), (PMID:16357216), (PMID:17531811), (PMID:18178619), (PMID:19820710), (PMID:23661684) RGD PMID:15973356, PMID:16357216, PMID:17531811, PMID:18178619, PMID:19820710, PMID:23661684 NCBI chr 6:128,388,084...128,453,234
Ensembl chr 6:128,388,053...128,434,183
JBrowse link
G Mir27a microRNA 27a ISO (MGI:MGI:5438907|PMID:22503104) RGD PMID:22503104 MGI:MGI:5438907 NCBI chr19:25,318,736...25,318,822
Ensembl chr19:25,318,736...25,318,822
JBrowse link
G Mir28 microRNA 28 ISO (MGI:MGI:5438907|PMID:22503104) RGD PMID:22503104 MGI:MGI:5438907 NCBI chr11:79,380,523...79,380,608
Ensembl chr11:79,380,523...79,380,608
JBrowse link
G Prkra protein activator of interferon induced protein kinase EIF2AK2 IEA
ISO
GO_REF:0000107
(PMID:23661684)
Ensembl
RGD
PMID:23661684 GO_REF:0000107 NCBI chr 3:63,489,081...63,507,918
Ensembl chr 3:63,489,074...63,507,926
JBrowse link
G Tarbp2 TARBP2 subunit of RISC loading complex ISS
ISO
GO_REF:0000024
(PMID:15973356), (PMID:16357216), (PMID:17531811), (PMID:18178619), (PMID:19820710), (PMID:23661684)
UniProt
RGD
PMID:15973356, PMID:16357216, PMID:17531811, PMID:18178619, PMID:19820710, PMID:23661684 GO_REF:0000024 NCBI chr 7:144,121,688...144,126,860
Ensembl chr 7:144,121,744...144,126,857
JBrowse link
G Zfp36 zinc finger protein 36 colocalizes_with ISO
ISS
(PMID:15766526)
GO_REF:0000024
RGD
UniProt
PMID:15766526 GO_REF:0000024 NCBI chr 1:85,380,088...85,382,565
Ensembl chr 1:85,380,088...85,382,569
JBrowse link
tRNA-intron endonuclease complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clp1 cleavage factor polyribonucleotide kinase subunit 1 ISO
ISS
(PMID:17495927)
GO_REF:0000024
RGD
UniProt
PMID:17495927 GO_REF:0000024 NCBI chr 3:72,125,269...72,137,122
Ensembl chr 3:72,125,273...72,128,973
JBrowse link
G Tsen2 tRNA splicing endonuclease subunit 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:147,455,506...147,490,869
Ensembl chr 4:147,455,533...147,490,733
JBrowse link
G Tsen34 tRNA splicing endonuclease subunit 34 IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 1:64,023,924...64,031,756
Ensembl chr 1:64,024,240...64,030,175
Ensembl chr 1:64,024,240...64,030,175
JBrowse link
G Tsen34l1 tRNA splicing endonuclease subunit 34-like 1 IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 1:64,092,224...64,100,061
Ensembl chr 1:64,092,226...64,099,277
JBrowse link
G Tsen54 tRNA splicing endonuclease subunit 54 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:104,358,401...104,366,926
Ensembl chr10:104,359,342...104,366,926
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20609
    protein-containing complex 6092
      catalytic complex 1487
        endonuclease complex 38
          endoribonuclease complex 32
            Ire1 complex 0
            Las1 complex 1
            RISC-loading complex 11
            ribonuclease III complex + 2
            ribonuclease P complex + 13
            tRNA-intron endonuclease complex 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.