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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cellular response to vascular endothelial growth factor stimulus
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Accession:GO:1902548 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to vascular endothelial growth factor stimulus.
Comment:ADAMTS12 (UniProt ID P58397) in human in PMID:17895370 inhibits the formation of VEGF-induced tubular structures in BAE-1 cells (endothelial cell line).
Synonyms:exact_synonym: down regulation of cellular response to VEGF;   down regulation of cellular response to vascular endothelial growth factor;   down regulation of cellular response to vascular endothelial growth factor stimulus;   downregulation of cellular response to VEGF;   downregulation of cellular response to vascular endothelial growth factor;   downregulation of cellular response to vascular endothelial growth factor stimulus;   negative regulation of cellular response to VEGF;   negative regulation of cellular response to vascular endothelial growth factor
 narrow_synonym: down regulation of cellular response to VEGFA;   down regulation of cellular response to VEGFB;   downregulation of cellular response to VEGFA;   downregulation of cellular response to VEGFB;   inhibition of cellular response to VEGF;   inhibition of cellular response to VEGFA;   inhibition of cellular response to VEGFB;   inhibition of cellular response to vascular endothelial growth factor;   inhibition of cellular response to vascular endothelial growth factor stimulus;   negative regulation of cellular response to VEGFA;   negative regulation of cellular response to VEGFB


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negative regulation of cellular response to vascular endothelial growth factor stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 involved_in ISO (PMID:17895370) RGD PMID:17895370 NCBI chr 2:61,039,072...61,340,687
Ensembl chr 2:61,039,053...61,340,697
JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 involved_in ISO (PMID:25147342) RGD PMID:25147342 NCBI chr13:50,091,644...50,153,808
Ensembl chr13:50,091,430...50,153,823
JBrowse link
negative regulation of vascular endothelial growth factor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgra2 adhesion G protein-coupled receptor A2 acts_upstream_of_or_within ISO MGI:4949903 (MGI:4949015|PMID:21421844) RGD PMID:21421844 MGI:4949015 NCBI chr16:69,094,587...69,133,015
Ensembl chr16:69,095,936...69,132,584
JBrowse link
G Cadm4 cell adhesion molecule 4 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:6271409|PMID:25893857)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:25893857 GO_REF:0000024 GO_REF:0000107 MGI:6271409 NCBI chr 1:81,365,200...81,369,841
Ensembl chr 1:81,365,138...81,370,109
JBrowse link
G Dab2ip DAB2 interacting protein involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:3831615|PMID:19033661)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:19033661 GO_REF:0000024 GO_REF:0000107 MGI:3831615 NCBI chr 3:14,889,263...15,060,286
Ensembl chr 3:14,889,510...15,060,286
JBrowse link
G Dcn decorin acts_upstream_of_or_within ISO (PMID:23798385) RGD PMID:23798385 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Hrg histidine-rich glycoprotein involved_in ISO
IEA
ISS
(PMID:16489009)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:16489009 GO_REF:0000024 GO_REF:0000107 NCBI chr11:81,621,274...81,639,938
Ensembl chr11:81,621,283...81,639,952
JBrowse link
G Il12a interleukin 12A acts_upstream_of
involved_in
ISO
IEA
UniProtKB:P29460 (PMID:30106099)
GO_REF:0000107
RGD
Ensembl
PMID:30106099 GO_REF:0000107 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il12b interleukin 12B acts_upstream_of ISO UniProtKB:P29459 (PMID:30106099) RGD PMID:30106099 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G LOC681544 similar to histidine-rich glycoprotein involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 Ensembl chr11:81,621,283...81,639,952 JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P15692 (PMID:30496354)
Ensembl
RGD
PMID:30496354 GO_REF:0000107 NCBI chr 8:107,275,849...107,381,088
Ensembl chr 8:107,275,725...107,380,933
JBrowse link
G Sema6a semaphorin 6A involved_in ISO (PMID:21536891) RGD PMID:21536891 NCBI chr18:41,330,519...41,451,813
Ensembl chr18:41,333,551...41,389,510
JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 involved_in ISO (PMID:21536891) RGD PMID:21536891 NCBI chr15:90,172,769...90,177,823
Ensembl chr15:90,172,975...90,175,802
JBrowse link
G Xdh xanthine dehydrogenase involved_in IEA
ISO
GO_REF:0000107
(PMID:18386220)
Ensembl
RGD
PMID:18386220 GO_REF:0000107 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    cellular process 18344
      negative regulation of cellular process 5117
        negative regulation of cellular response to growth factor stimulus 104
          negative regulation of cellular response to vascular endothelial growth factor stimulus 14
            negative regulation of endothelial cell chemotaxis to vascular endothelial growth factor 0
            negative regulation of vascular endothelial growth factor signaling pathway 12
Path 2
Term Annotations click to browse term
  biological_process 19491
    response to stimulus 10357
      response to chemical 6185
        response to organic substance 3889
          response to growth factor 820
            cellular response to growth factor stimulus 780
              regulation of cellular response to growth factor stimulus 299
                regulation of cellular response to vascular endothelial growth factor stimulus 25
                  negative regulation of cellular response to vascular endothelial growth factor stimulus 14
                    negative regulation of endothelial cell chemotaxis to vascular endothelial growth factor 0
                    negative regulation of vascular endothelial growth factor signaling pathway 12
paths to the root