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ONTOLOGY REPORT - ANNOTATIONS


Term:deactivation of mitotic spindle assembly checkpoint
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Accession:GO:1902426 term browser browse the term
Definition:A positive regulation of the mitotic metaphase/anaphase transition that results from deactivation of the mitotic spindle assembly checkpoint.
Comment:A mitotic spindle assembly checkpoint is either activated or switched off; no other means of reducing the frequency, rate or extent of this process are currently known.
Synonyms:exact_synonym: down regulation of mitotic cell cycle spindle assembly checkpoint;   down regulation of mitotic spindle assembly checkpoint;   downregulation of mitotic cell cycle spindle assembly checkpoint;   downregulation of mitotic spindle assembly checkpoint;   mitotic spindle assembly checkpoint silencing;   mitotic spindle assembly deactivation;   negative regulation of mitotic cell cycle spindle assembly checkpoint
 broad_synonym: negative regulation of mitotic spindle assembly checkpoint
 related_synonym: down regulation of Mad2-dependent checkpoint;   downregulation of Mad2-dependent checkpoint;   inhibition of Mad2-dependent checkpoint;   inhibition of mitotic cell cycle spindle assembly checkpoint;   inhibition of mitotic spindle assembly checkpoint;   negative regulation of Mad2-dependent checkpoint



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deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:22581055) RGD PMID:22581055 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 involved_in ISO (PMID:19010891) RGD PMID:19010891 NCBI chr12:14,320,892...14,630,750
Ensembl chr12:14,320,892...14,630,703
JBrowse link
G Mad2l1bp MAD2L1 binding protein involved_in ISO (PMID:18022368) RGD PMID:18022368 NCBI chr 9:14,832,133...14,836,458
Ensembl chr 9:14,832,132...14,837,447
JBrowse link
G Prap1 proline-rich acidic protein 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:24374861)
UniProt
RGD
PMID:24374861 GO_REF:0000024 NCBI chr 1:194,883,078...194,886,874
Ensembl chr 1:194,883,078...194,886,872
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20091
    cellular process 18675
      cell cycle process 1253
        negative regulation of cell cycle process 311
          negative regulation of mitotic spindle assembly checkpoint signaling 4
            deactivation of mitotic spindle assembly checkpoint 4
Path 2
Term Annotations click to browse term
  biological_process 20091
    cellular process 18675
      cellular component organization or biogenesis 6788
        cellular component organization 6542
          organelle organization 3671
            organelle fission 534
              nuclear division 481
                mitotic nuclear division 304
                  mitotic sister chromatid segregation 175
                    mitotic sister chromatid separation 73
                      regulation of mitotic sister chromatid separation 70
                        metaphase/anaphase transition of mitotic cell cycle 69
                          regulation of mitotic metaphase/anaphase transition 65
                            negative regulation of mitotic metaphase/anaphase transition 42
                              mitotic spindle assembly checkpoint signaling 40
                                regulation of mitotic cell cycle spindle assembly checkpoint 17
                                  negative regulation of mitotic spindle assembly checkpoint signaling 4
                                    deactivation of mitotic spindle assembly checkpoint 4
paths to the root