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ONTOLOGY REPORT - ANNOTATIONS


Term:deactivation of mitotic spindle assembly checkpoint
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Accession:GO:1902426 term browser browse the term
Definition:A positive regulation of the mitotic metaphase/anaphase transition that results from deactivation of the mitotic spindle assembly checkpoint.
Comment:A mitotic spindle assembly checkpoint is either activated or switched off; no other means of reducing the frequency, rate or extent of this process are currently known.
Synonyms:exact_synonym: down regulation of mitotic cell cycle spindle assembly checkpoint;   down regulation of mitotic spindle assembly checkpoint;   downregulation of mitotic cell cycle spindle assembly checkpoint;   downregulation of mitotic spindle assembly checkpoint;   mitotic spindle assembly checkpoint silencing;   mitotic spindle assembly deactivation;   negative regulation of mitotic cell cycle spindle assembly checkpoint
 broad_synonym: negative regulation of mitotic spindle assembly checkpoint
 related_synonym: down regulation of Mad2-dependent checkpoint;   downregulation of Mad2-dependent checkpoint;   inhibition of Mad2-dependent checkpoint;   inhibition of mitotic cell cycle spindle assembly checkpoint;   inhibition of mitotic spindle assembly checkpoint;   negative regulation of Mad2-dependent checkpoint



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deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mad1l1 mitotic arrest deficient 1 like 1 involved_in ISO (PMID:19010891) RGD PMID:19010891 NCBI chr12:19,434,782...19,744,574
Ensembl chr12:14,320,892...14,630,703
JBrowse link
G Mad2l1bp MAD2L1 binding protein involved_in ISO (PMID:18022368) RGD PMID:18022368 NCBI chr 9:14,832,133...14,836,458
Ensembl chr 9:14,832,132...14,837,447
JBrowse link
G Prap1 proline-rich acidic protein 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:24374861)
UniProt
RGD
PMID:24374861 GO_REF:0000024 NCBI chr 1:194,883,078...194,886,874
Ensembl chr 1:194,883,078...194,886,872
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20546
    cellular process 19536
      cell cycle process 1311
        negative regulation of cell cycle process 307
          negative regulation of mitotic spindle assembly checkpoint signaling 5
            deactivation of mitotic spindle assembly checkpoint 3
Path 2
Term Annotations click to browse term
  biological_process 20546
    cellular process 19536
      cellular component organization or biogenesis 7196
        cellular component organization 6911
          organelle organization 3697
            organelle fission 518
              nuclear division 459
                mitotic nuclear division 274
                  mitotic sister chromatid segregation 184
                    regulation of mitotic sister chromatid segregation 50
                      negative regulation of mitotic sister chromatid segregation 42
                        negative regulation of mitotic sister chromatid separation 42
                          negative regulation of mitotic metaphase/anaphase transition 42
                            mitotic spindle assembly checkpoint signaling 40
                              regulation of mitotic cell cycle spindle assembly checkpoint 19
                                negative regulation of mitotic spindle assembly checkpoint signaling 5
                                  deactivation of mitotic spindle assembly checkpoint 3
paths to the root