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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
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Accession:GO:1902236 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.
Synonyms:exact_synonym: down regulation of ER stress-induced apoptosis;   down regulation of apoptosis in response to ER stress;   down regulation of apoptosis triggered by ER stress;   down regulation of endoplasmic reticulum stress-induced apoptosis;   down regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;   down regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress;   downregulation of ER stress-induced apoptosis;   downregulation of apoptosis in response to ER stress;   downregulation of apoptosis triggered by ER stress;   downregulation of endoplasmic reticulum stress-induced apoptosis;   downregulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;   downregulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress;   negative regulation of ER stress-induced apoptosis;   negative regulation of apoptosis in response to ER stress;   negative regulation of apoptosis triggered by ER stress;   negative regulation of endoplasmic reticulum stress-induced apoptosis;   negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;   negative regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress
 narrow_synonym: inhibition of ER stress-induced apoptosis;   inhibition of apoptosis in response to ER stress;   inhibition of apoptosis triggered by ER stress;   inhibition of endoplasmic reticulum stress-induced apoptosis;   inhibition of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;   inhibition of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress


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negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2l1 Bcl2-like 1 involved_in ISO
ISS		 (PMID:29507230)
GO_REF:0000024		 RGD
UniProt		 PMID:29507230 GO_REF:0000024 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Creb3 cAMP responsive element binding protein 3 involved_in ISO (PMID:16940180) RGD PMID:16940180 NCBI chr 5:57,817,865...57,823,233
Ensembl chr 5:57,817,832...57,824,390 		JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 involved_in IMP
ISO		 PMID:15665855
(MGI:5616321|PMID:15665855)		 RGD PMID:15665855 PMID:15665855 MGI:5616321, RGD:1558627 NCBI chr 3:77,952,589...77,993,513
Ensembl chr 3:77,952,540...77,993,456 		JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1341830|MGI:99682 (PMID:22240901)		 Ensembl
RGD		 PMID:22240901 GO_REF:0000107 NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in ISO
IBA		 (PMID:15102845)
GO_REF:0000033		 RGD
GO_Central		 PMID:15102845 GO_REF:0000033 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:12150907), (PMID:20625543) RGD PMID:12150907 PMID:20625543 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:12150907), (PMID:20625543) RGD PMID:12150907 PMID:20625543 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in ISO (MGI:5495588|PMID:23453807) RGD PMID:23453807 MGI:5495588 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:21857923) RGD PMID:21857923 NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Ngf nerve growth factor involved_in NAS PMID:21266243 ParkinsonsUK-UCL PMID:21266243 RGD:10047230 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5495588|PMID:23453807)
UniProtKB:P58281 (PMID:23453807)		 ParkinsonsUK-UCL
Ensembl
RGD		 PMID:23453807 GO_REF:0000024 GO_REF:0000107 MGI:5495588 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO
IEA		 UniProtKB:Q99LX0 (PMID:14652021)
GO_REF:0000107
(MGI:5613479|PMID:14652021)		 RGD
Ensembl		 PMID:14652021 GO_REF:0000107 MGI:5613479 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 acts_upstream_of_or_within ISO MGI:2181360 (PMID:20811152) RGD PMID:20811152 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISS
ISO		 GO_REF:0000024
(PMID:10973942), (PMID:11439185), (PMID:12150907), (PMID:21113145), (PMID:23453807)
(MGI:5433837|PMID:21113145)		 ParkinsonsUK-UCL
RGD		 PMID:10973942 PMID:11439185 PMID:12150907 PMID:21113145 PMID:23453807 GO_REF:0000024 MGI:5433837 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO (MGI:5619464|PMID:21216966) RGD PMID:21216966 MGI:5619464 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
G Selenos selenoprotein S involved_in ISO
IEA		 (PMID:17210132)
GO_REF:0000107		 RGD
Ensembl		 PMID:17210132 GO_REF:0000107 NCBI chr 1:119,659,779...119,669,546
Ensembl chr 1:119,659,751...119,669,833 		JBrowse link
G Syvn1 synoviolin 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:12459480), (PMID:17059562)
MGI:2679656 (PMID:15611074)		 RGD PMID:12459480 PMID:15611074 PMID:17059562 NCBI chr 1:203,339,235...203,346,137
Ensembl chr 1:203,339,619...203,346,152 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in
acts_upstream_of_or_within		 ISO (PMID:21075086)
MGI:1913418 (PMID:22240901)		 RGD PMID:21075086 PMID:22240901 NCBI chr 7:130,527,313...130,542,567
Ensembl chr 7:130,527,316...130,543,633 		JBrowse link
G Txndc12 thioredoxin domain containing 12 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:18628206)
GO_REF:0000107		 RGD
Ensembl		 PMID:18628206 GO_REF:0000107 NCBI chr 5:123,587,854...123,612,886
Ensembl chr 5:123,586,781...123,612,870 		JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in ISO (MGI:3629256|PMID:16571599) RGD PMID:16571599 MGI:3629256 NCBI chr14:73,810,478...73,834,993
Ensembl chr14:73,810,404...73,835,602 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO
IEA
IMP		 (PMID:19135031)
GO_REF:0000107
PMID:20625543		 RGD
Ensembl		 PMID:19135031 PMID:20625543 GO_REF:0000107, RGD:10047191 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hyou1 hypoxia up-regulated 1 involved_in ISO
IEA		 (MGI:3697528|PMID:17116640)
GO_REF:0000107		 RGD
Ensembl		 PMID:17116640 GO_REF:0000107 MGI:3697528 NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA		 UniProtKB:O15354 (MGI:3697528|PMID:17116640), (MGI:5495588|PMID:23453807)
GO_REF:0000107		 RGD
Ensembl		 PMID:17116640 PMID:23453807 GO_REF:0000107 MGI:3697528 MGI:5495588 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    negative regulation of biological process 5812
      negative regulation of response to stimulus 1888
        negative regulation of response to endoplasmic reticulum stress 46
          negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 22
            negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway 2
Path 2
Term Annotations click to browse term
  biological_process 20413
    biological regulation 13755
      regulation of biological process 13322
        regulation of cellular process 12748
          signal transduction 7209
            apoptotic signaling pathway 690
              regulation of apoptotic signaling pathway 462
                negative regulation of apoptotic signaling pathway 264
                  negative regulation of intrinsic apoptotic signaling pathway 118
                    negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 22
                      negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway 2
paths to the root