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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
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Accession:GO:1902230 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage.
Synonyms:exact_synonym: down regulation of intrinsic apoptotic signaling pathway in response to DNA damage;   downregulation of intrinsic apoptotic signaling pathway in response to DNA damage
 narrow_synonym: inhibition of intrinsic apoptotic signaling pathway in response to DNA damage
 related_synonym: down regulation of DNA damage response, signal transduction resulting in induction of apoptosis;   downregulation of DNA damage response, signal transduction resulting in induction of apoptosis;   inhibition of DNA damage response, signal transduction resulting in induction of apoptosis;   negative regulation of DNA damage response, signal transduction resulting in induction of apoptosis


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negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACKR3 atypical chemokine receptor 3 involved_in IMP (PMID:20388803) BHF-UCL PMID:20388803 NCBI chr 2:236,537,122...236,582,354
Ensembl chr 2:236,567,787...236,582,354 		JBrowse link
G ATAD5 ATPase family AAA domain containing 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15983387) Ensembl
MGI		 PMID:15983387 GO_REF:0000107 NCBI chr17:30,831,966...30,895,869
Ensembl chr17:30,831,966...30,895,869 		JBrowse link
G BCL2L1 BCL2 like 1 involved_in IDA (PMID:16608847) BHF-UCL PMID:16608847 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BID BH3 interacting domain death agonist involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:26219591) Ensembl
MGI		 PMID:26219591 GO_REF:0000107 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770 		JBrowse link
G CCAR2 cell cycle and apoptosis regulator 2 involved_in IMP (PMID:23352644) UniProt PMID:23352644 NCBI chr 8:22,604,757...22,621,514
Ensembl chr 8:22,604,757...22,620,964 		JBrowse link
G CDKN2D cyclin dependent kinase inhibitor 2D involved_in IMP (PMID:15750620) BHF-UCL PMID:15750620 NCBI chr19:10,566,460...10,568,979
Ensembl chr19:10,566,460...10,569,059 		JBrowse link
G CLU clusterin involved_in IMP (PMID:16113678) BHF-UCL PMID:16113678 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 involved_in IDA (PMID:20388803) BHF-UCL PMID:20388803 NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493 		JBrowse link
G DDIAS DNA damage induced apoptosis suppressor involved_in IMP
IEA		 (PMID:24214091) UniProt
InterPro		 PMID:24214091 GO_REF:0000002 NCBI chr11:82,901,736...82,934,659
Ensembl chr11:82,899,975...82,958,277 		JBrowse link
G SFRP2 secreted frizzled related protein 2 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 4:153,780,591...153,789,083
Ensembl chr 4:153,780,591...153,789,083 		JBrowse link
G SNAI1 snail family transcriptional repressor 1 involved_in IMP (PMID:15314165) BHF-UCL PMID:15314165 NCBI chr20:49,982,980...49,988,886
Ensembl chr20:49,982,980...49,988,886 		JBrowse link
G SNAI2 snail family transcriptional repressor 2 involved_in IMP (PMID:15314165) BHF-UCL PMID:15314165 NCBI chr 8:48,917,598...48,921,429
Ensembl chr 8:48,917,598...48,921,740 		JBrowse link
G TMEM161A transmembrane protein 161A involved_in IMP (PMID:16551573) BHF-UCL PMID:16551573 NCBI chr19:19,119,169...19,138,478
Ensembl chr19:19,119,169...19,138,513 		JBrowse link
G TPT1 tumor protein, translationally-controlled 1 acts_upstream_of_or_within IMP (PMID:11598139) MGI PMID:11598139 NCBI chr13:45,333,471...45,341,183
Ensembl chr13:45,333,471...45,341,284 		JBrowse link
G TRIM32 tripartite motif containing 32 involved_in IDA (PMID:18632609) BHF-UCL PMID:18632609 NCBI chr 9:116,687,305...116,701,299
Ensembl chr 9:116,687,305...116,701,300 		JBrowse link
G USP47 ubiquitin specific peptidase 47 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19966869) Ensembl
MGI		 PMID:19966869 GO_REF:0000107 NCBI chr11:11,841,972...11,961,887
Ensembl chr11:11,841,423...11,961,887 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATAD5 ATPase family AAA domain containing 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:30,831,966...30,895,869
Ensembl chr17:30,831,966...30,895,869 		JBrowse link
G BCL2 BCL2 apoptosis regulator involved_in TAS (PMID:1286168) BHF-UCL PMID:1286168 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L12 BCL2 like 12 acts_upstream_of_or_within ISO (PMID:20837658) MGI PMID:20837658 NCBI chr19:49,665,142...49,673,916
Ensembl chr19:49,665,142...49,673,916 		JBrowse link
G CD44 CD44 molecule (IN blood group) involved_in IDA (PMID:17045821) BHF-UCL PMID:17045821 NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402 		JBrowse link
G CD74 CD74 molecule involved_in IEA
IBA
IMP		 (PMID:17045821) Ensembl
GO_Central
BHF-UCL		 PMID:17045821 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:150,401,639...150,412,910
Ensembl chr 5:150,401,637...150,412,969 		JBrowse link
G ELL3 elongation factor for RNA polymerase II 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22768269) Ensembl
MGI		 PMID:22768269 GO_REF:0000107 NCBI chr15:43,772,620...43,776,966
Ensembl chr15:43,772,605...43,777,315 		JBrowse link
G ING2 inhibitor of growth family member 2 involved_in TAS (PMID:21124965) BHF-UCL PMID:21124965 NCBI chr 4:183,505,058...183,512,429
Ensembl chr 4:183,505,058...183,512,429 		JBrowse link
G KDM1A lysine demethylase 1A involved_in IMP (PMID:17805299) BHF-UCL PMID:17805299 NCBI chr 1:23,019,468...23,083,689
Ensembl chr 1:23,019,443...23,083,689 		JBrowse link
G MARCHF7 membrane associated ring-CH-type finger 7 involved_in IMP (PMID:29295817) UniProt PMID:29295817 NCBI chr 2:159,712,506...159,771,027
Ensembl chr 2:159,712,457...159,771,027 		JBrowse link
G MIF macrophage migration inhibitory factor involved_in IDA (PMID:17045821) BHF-UCL PMID:17045821 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227 		JBrowse link
G MUC1 mucin 1, cell surface associated involved_in IDA (PMID:15710329) BHF-UCL PMID:15710329 NCBI chr 1:155,185,824...155,192,915
Ensembl chr 1:155,185,824...155,192,916 		JBrowse link
G SIRT1 sirtuin 1 involved_in IEA
ISS		 (PMID:11672522) Ensembl
BHF-UCL		 PMID:11672522 GO_REF:0000107 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
G TAF9 TATA-box binding protein associated factor 9 involved_in IC (PMID:15899866) BHF-UCL PMID:15899866 NCBI chr 5:69,364,743...69,369,824
Ensembl chr 5:69,362,026...69,370,013 		JBrowse link
G TAF9B TATA-box binding protein associated factor 9b involved_in IC (PMID:15899866) BHF-UCL PMID:15899866 NCBI chr  X:78,129,748...78,139,650
Ensembl chr  X:78,129,748...78,139,650 		JBrowse link
G TRIAP1 TP53 regulated inhibitor of apoptosis 1 involved_in IMP (PMID:15735003) BHF-UCL PMID:15735003 NCBI chr12:120,443,964...120,446,384
Ensembl chr12:120,443,964...120,446,384 		JBrowse link
G ZNF385A zinc finger protein 385A involved_in IMP (PMID:17719541) UniProt PMID:17719541 NCBI chr12:54,369,136...54,391,298
Ensembl chr12:54,369,133...54,391,298 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19669
    cellular process 18300
      regulation of cellular process 12447
        regulation of cellular response to stress 596
          regulation of intrinsic apoptotic signaling pathway in response to DNA damage 43
            negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage 31
              negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 16
Path 2
Term Annotations click to browse term
  biological_process 19669
    biological regulation 13397
      regulation of biological process 13016
        regulation of cellular process 12447
          signal transduction 6573
            apoptotic signaling pathway 709
              regulation of apoptotic signaling pathway 463
                negative regulation of apoptotic signaling pathway 281
                  negative regulation of intrinsic apoptotic signaling pathway 130
                    negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage 31
                      negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 16
paths to the root