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ONTOLOGY REPORT - ANNOTATIONS

Term:erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process
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Accession:GO:1902221 term browser browse the term
Definition:The chemical reactions and pathways involving erythrose 4-phosphate/phosphoenolpyruvate family amino acid.
Synonyms:exact_synonym: erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolism


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'de novo' NAD biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718 		JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA
IBA		 GO_REF:0000104
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000104 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000104		 GO_Central
UniProt		 GO_REF:0000033 GO_REF:0000104 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730 		JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000104		 GO_Central
UniProt		 GO_REF:0000033 GO_REF:0000104 NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324 		JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881 		JBrowse link
G Kynu kynureninase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
dopamine biosynthetic process from tyrosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Th tyrosine hydroxylase acts_upstream_of_or_within
involved_in		 IDA
ISO
IBA
IMP		 MGI:1860450 (PMID:7592982), (PMID:7715703), (PMID:9520487)
GO_REF:0000033
PMID:11943812		 RGD
GO_Central		 PMID:7592982 PMID:7715703 PMID:9520487 PMID:2427363 PMID:11943812 More... GO_REF:0000033, RGD:1580046, RGD:5129111, RGD:5130972 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
L-phenylalanine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fah fumarylacetoacetate hydrolase involved_in IEA
IBA		 GO_REF:0000041
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000041 NCBI chr 1:138,548,830...138,571,599
Ensembl chr 1:138,548,834...138,571,505 		JBrowse link
G Gstz1 glutathione S-transferase zeta 1 involved_in IEA
IBA		 GO_REF:0000041
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000041 NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284 		JBrowse link
G Hgd homogentisate 1, 2-dioxygenase involved_in IEA
IBA		 GO_REF:0000041
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000041 NCBI chr11:63,086,750...63,138,325
Ensembl chr11:63,086,752...63,138,323 		JBrowse link
G Hpd 4-hydroxyphenylpyruvate dioxygenase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr12:33,381,397...33,392,750
Ensembl chr12:33,381,231...33,392,766 		JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:17356132), (PMID:25767141) RGD PMID:17356132 PMID:25767141 NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562 		JBrowse link
G Pah phenylalanine hydroxylase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130 		JBrowse link
G Qdpr quinoid dihydropteridine reductase involved_in IEP
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:4155291 GO_REF:0000033, RGD:5128604 NCBI chr14:65,670,251...65,683,853
Ensembl chr14:65,670,131...65,683,854 		JBrowse link
G Tat tyrosine aminotransferase involved_in IEA
IBA		 GO_REF:0000041
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000041 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031 		JBrowse link
L-phenylalanine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pah phenylalanine hydroxylase IDA RGD PMID:16953590 RGD:1601531 NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130 		JBrowse link
G Pcbd1 pterin-4 alpha-carbinolamine dehydratase 1 involved_in IDA PMID:1465414 CAFA PMID:1465414 RGD:12792994 NCBI chr20:29,037,545...29,044,322
Ensembl chr20:28,953,864...29,044,292
Ensembl chr20:28,953,864...29,044,292 		JBrowse link
G Spr sepiapterin reductase acts_upstream_of_or_within ISO MGI:3757641 (PMID:16532389) RGD PMID:16532389 NCBI chr 4:117,671,948...117,676,292
Ensembl chr 4:117,671,949...117,675,678 		JBrowse link
melanin biosynthetic process from tyrosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dct dopachrome tautomerase involved_in ISO (MGI:3690794|PMID:2169885), (MGI:6827472|PMID:33100333) RGD PMID:2169885 PMID:33100333 MGI:3690794 MGI:6827472 NCBI chr15:95,062,006...95,100,863
Ensembl chr15:95,062,003...95,100,836 		JBrowse link
G Oca2 OCA2 melanosomal transmembrane protein involved_in ISO (PMID:25513726), (PMID:32966160) RGD PMID:25513726 PMID:32966160 NCBI chr 1:107,116,278...107,446,093
Ensembl chr 1:107,116,278...107,446,074 		JBrowse link
G Slc45a2 solute carrier family 45, member 2 involved_in ISO (PMID:32966160)
(PMID:35469906)
(MGI:7338895|PMID:35469906)		 RGD PMID:32966160 PMID:35469906 MGI:7338895 NCBI chr 2:59,963,599...59,996,408
Ensembl chr 2:59,963,706...59,996,317 		JBrowse link
tryptophan metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856102 (PMID:4147174) RGD PMID:4147174 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase IDA RGD PMID:10719243 PMID:3899109 PMID:3400092 RGD:2290190, RGD:2291804, RGD:2290313 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511 		JBrowse link
tyrosine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pah phenylalanine hydroxylase involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:16953590 GO_REF:0000033, RGD:1601531 NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130 		JBrowse link
tyrosine biosynthetic process, by oxidation of phenylalanine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pah phenylalanine hydroxylase involved_in
acts_upstream_of_or_within		 IDA
IEA
ISO		 GO_REF:0000108
MGI:1857271 (MGI:58807|PMID:2308957)		 GOC
RGD		 PMID:2308957 PMID:10839989 GO_REF:0000108 MGI:58807, RGD:1601535 NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130 		JBrowse link
G Pcbd1 pterin-4 alpha-carbinolamine dehydratase 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr20:29,037,545...29,044,322
Ensembl chr20:28,953,864...29,044,292
Ensembl chr20:28,953,864...29,044,292 		JBrowse link
G Pcbd2 pterin-4 alpha-carbinolamine dehydratase 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr17:8,845,161...8,896,343
Ensembl chr17:8,845,084...8,910,539 		JBrowse link
G Txndc15 thioredoxin domain containing 15 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr17:8,898,074...8,910,538
Ensembl chr17:8,845,084...8,910,539 		JBrowse link
tyrosine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fah fumarylacetoacetate hydrolase involved_in IEA
IBA		 GO_REF:0000104
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000104 NCBI chr 1:138,548,830...138,571,599
Ensembl chr 1:138,548,834...138,571,505 		JBrowse link
G Gstz1 glutathione S-transferase zeta 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284 		JBrowse link
G Hpd 4-hydroxyphenylpyruvate dioxygenase involved_in
acts_upstream_of_or_within		 TAS
IBA
ISO
IDA		 GO_REF:0000033
(PMID:31537781)
PMID:8814303		 GO_Central
RGD		 PMID:31537781 PMID:12867153 PMID:8814303 GO_REF:0000033, RGD:632936, RGD:8554707 NCBI chr12:33,381,397...33,392,750
Ensembl chr12:33,381,231...33,392,766 		JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:17356132) RGD PMID:17356132 NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562 		JBrowse link
G Tat tyrosine aminotransferase involved_in ISO
IBA
ISS		 (PMID:7999802)
(PMID:21153519)
GO_REF:0000033
(MGI:5430853|PMID:21153519)
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:7999802 PMID:21153519 GO_REF:0000024 GO_REF:0000033 MGI:5430853 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031 		JBrowse link
tyrosine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856102 (PMID:4147174) RGD PMID:4147174 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Hgd homogentisate 1, 2-dioxygenase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr11:63,086,750...63,138,325
Ensembl chr11:63,086,752...63,138,323 		JBrowse link
G Iyd iodotyrosine deiodinase involved_in ISO
IBA
ISS		 (PMID:25395621)
(PMID:19777994)
GO_REF:0000033
(MGI:7260100|PMID:19777994)
(PMID:25395621), (PMID:28157283)
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:19777994 PMID:25395621 PMID:28157283 GO_REF:0000024 GO_REF:0000033 MGI:7260100 NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319 		JBrowse link
G Thap4 THAP domain containing 4 involved_in ISO
ISS		 (PMID:30524950)
GO_REF:0000024		 RGD
UniProt		 PMID:30524950 GO_REF:0000024 NCBI chr 9:94,242,581...94,282,312
Ensembl chr 9:94,242,581...94,282,306 		JBrowse link
G Ttc36 tetratricopeptide repeat domain 36 acts_upstream_of_or_within ISO MGI:5588394 (PMID:31537781) RGD PMID:31537781 NCBI chr 8:45,112,737...45,116,345 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20134
    cellular process 19326
      metabolic process 12309
        primary metabolic process 10935
          amino acid metabolic process 302
            proteinogenic amino acid metabolic process 174
              erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process 27
                L-phenylalanine metabolic process + 10
                erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process + 4
                erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process + 8
                tryptophan metabolic process + 8
                tyrosine metabolic process + 18
Path 2
Term Annotations click to browse term
  biological_process 20134
    cellular process 19326
      metabolic process 12309
        small molecule metabolic process 1899
          organic acid metabolic process 1034
            oxoacid metabolic process 1023
              carboxylic acid metabolic process 1008
                alpha-amino acid metabolic process 220
                  L-amino acid metabolic process 192
                    erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process 27
                      L-phenylalanine metabolic process + 10
                      erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process + 4
                      erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process + 8
                      tryptophan metabolic process + 8
                      tyrosine metabolic process + 18
paths to the root