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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of mitochondrial membrane permeability involved in apoptotic process
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Accession:GO:1902110 term browser browse the term
Definition:Any positive regulation of mitochondrial membrane permeability that is involved in apoptotic process.
Comment:Individual components of the mitochondrial permeability transition pore complex, such as the voltage-dependent anion channel (VDAC), the adenine nucleotide translocase (ANT) and cyclophilin-D (CyP-D), are involved in this process.
Synonyms:exact_synonym: positive regulation of mitochondrial membrane permeability involved in apoptotic cell death;   positive regulation of mitochondrial membrane permeability involved in apoptotic programmed cell death;   positive regulation of mitochondrial membrane permeability involved in programmed cell death by apoptosis;   positive regulation of transport across mitochondrial membrane involved in apoptotic cell death;   positive regulation of transport across mitochondrial membrane involved in apoptotic process;   positive regulation of transport across mitochondrial membrane involved in apoptotic programmed cell death;   positive regulation of transport across mitochondrial membrane involved in programmed cell death by apoptosis
 narrow_synonym: mitochondrial membrane permeability transition involved in apoptosis;   mitochondrial membrane permeability transition involved in apoptotic cell death;   mitochondrial membrane permeability transition involved in apoptotic process;   mitochondrial membrane permeability transition involved in apoptotic program;   mitochondrial membrane permeability transition involved in apoptotic programmed cell death;   mitochondrial membrane permeability transition involved in programmed cell death by apoptosis;   mitochondrial membrane permeability transition involved in type I programmed cell death;   mitochondrial membrane permeabilization involved in apoptosis;   mitochondrial membrane permeabilization involved in apoptotic cell death;   mitochondrial membrane permeabilization involved in apoptotic process;   mitochondrial membrane permeabilization involved in apoptotic program;   mitochondrial membrane permeabilization involved in apoptotic programmed cell death;   mitochondrial membrane permeabilization involved in programmed cell death by apoptosis;   mitochondrial membrane permeabilization involved in type I programmed cell death;   mitochondrial permeability transition involved in apoptosis;   mitochondrial permeability transition involved in apoptotic cell death;   mitochondrial permeability transition involved in apoptotic process;   mitochondrial permeability transition involved in apoptotic program;   mitochondrial permeability transition involved in apoptotic programmed cell death;   mitochondrial permeability transition involved in programmed cell death by apoptosis;   mitochondrial permeability transition involved in type I programmed cell death;   positive regulation of mitochondrial membrane permeability involved in apoptosis;   positive regulation of mitochondrial membrane permeability involved in apoptotic program;   positive regulation of mitochondrial membrane permeability involved in type I programmed cell death;   positive regulation of transport across mitochondrial membrane involved in apoptosis;   positive regulation of transport across mitochondrial membrane involved in apoptotic program;   positive regulation of transport across mitochondrial membrane involved in type I programmed cell death
 related_synonym: mitochondrial membrane permeability transition involved in signaling (initiator) caspase activity;   mitochondrial membrane permeabilization involved in signaling (initiator) caspase activity;   mitochondrial permeability transition involved in signaling (initiator) caspase activity;   positive regulation of mitochondrial membrane permeability involved in signaling (initiator) caspase activity;   positive regulation of transport across mitochondrial membrane involved in signaling (initiator) caspase activity

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positive regulation of mitochondrial membrane permeability involved in apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936509:4,729,984...4,826,367
Ensembl chrNW_004936509:4,732,930...4,826,443 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15967824) Ensembl
MGI		 PMID:15967824 GO_REF:0000107 NCBI chrNW_004936664:2,968,103...2,973,652
Ensembl chrNW_004936664:2,967,865...2,973,820 		JBrowse link
G Bcl2l11 BCL2 like 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15967824) Ensembl
MGI		 PMID:15967824 GO_REF:0000107 NCBI chrNW_004936783:15,493...50,959
Ensembl chrNW_004936783:18,194...50,983 		JBrowse link
G Stpg1 sperm tail PG-rich repeat containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:9,358,114...9,398,379
Ensembl chrNW_004936474:9,358,116...9,398,271 		JBrowse link
mitochondrial outer membrane permeabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bid BH3 interacting domain death agonist involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20436477) Ensembl
MGI		 PMID:20436477 GO_REF:0000107 NCBI chrNW_004936807:708,340...750,127
Ensembl chrNW_004936807:708,276...750,093 		JBrowse link
G Bloc1s2 biogenesis of lysosomal organelles complex 1 subunit 2 involved_in ISO (PMID:18188704) UniProt PMID:18188704 NCBI chrNW_004939661:2,128...6,384 JBrowse link
G Bnip3 BCL2 interacting protein 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936486:18,449,371...18,460,435
Ensembl chrNW_004936486:18,448,494...18,455,927 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936757:499,485...523,494
Ensembl chrNW_004936757:499,147...523,541 		JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11700312) Ensembl
MGI		 PMID:11700312 GO_REF:0000107 NCBI chrNW_004936514:6,223,745...6,401,985
Ensembl chrNW_004936514:6,223,719...6,341,326 		JBrowse link
G Rhot1 ras homolog family member T1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936538:2,658,225...2,725,889
Ensembl chrNW_004936538:2,658,172...2,726,092 		JBrowse link
G Rhot2 ras homolog family member T2 involved_in ISO (PMID:12482879) UniProt PMID:12482879 NCBI chrNW_004936501:336,506...341,671 JBrowse link
G Rtl10 retrotransposon Gag like 10 involved_in ISO (PMID:23055042) UniProt PMID:23055042 NCBI chrNW_004936619:3,755,537...3,760,909 JBrowse link
G Vdac2 voltage dependent anion channel 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936521:4,122,447...4,136,228
Ensembl chrNW_004936521:4,122,270...4,136,380 		JBrowse link
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa2 acetyl-CoA acyltransferase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936497:13,242,644...13,269,007
Ensembl chrNW_004936497:13,242,644...13,269,532 		JBrowse link
G Bak1 BCL2 antagonist/killer 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:25,347,608...25,354,772
Ensembl chrNW_004936476:25,347,545...25,355,789 		JBrowse link
G Bcl2l1 BCL2 like 1 involved_in ISO (PMID:15901672), (PMID:9393856) ComplexPortal PMID:9393856 PMID:15901672 NCBI chrNW_004936485:18,654,046...18,707,324 JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936745:344,837...350,950
Ensembl chrNW_004936745:345,635...351,749 		JBrowse link
G Gclc glutamate-cysteine ligase catalytic subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15288121) Ensembl
MGI		 PMID:15288121 GO_REF:0000107 NCBI chrNW_004936476:7,371,270...7,418,756
Ensembl chrNW_004936476:7,371,149...7,418,958 		JBrowse link
G Ier3 immediate early response 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19096392) Ensembl
MGI		 PMID:19096392 GO_REF:0000107 NCBI chrNW_004936837:401,475...402,769
Ensembl chrNW_004936837:401,524...402,741 		JBrowse link
G LOC101955831 heat shock 70 kDa protein 1 involved_in ISO (PMID:20625543) ParkinsonsUK-UCL PMID:20625543 NCBI chrNW_004936727:1,718,952...1,721,691 JBrowse link
G LOC101956126 heat shock 70 kDa protein 1 involved_in ISO (PMID:20625543) ParkinsonsUK-UCL PMID:20625543 NCBI chrNW_004936727:1,732,323...1,735,128 JBrowse link
G Mpv17l MPV17 mitochondrial inner membrane protein like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936501:3,017,071...3,028,294
Ensembl chrNW_004936501:3,017,012...3,027,181 		JBrowse link
G Slc25a4 solute carrier family 25 member 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936554:4,130,461...4,135,046
Ensembl chrNW_004936554:4,130,459...4,135,044 		JBrowse link
G Slc25a5 solute carrier family 25 member 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936479:10,432,172...10,435,154 JBrowse link
G Slc25a6 solute carrier family 25 member 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936644:3,793,434...3,795,182 JBrowse link
G Slc35f6 solute carrier family 35 member F6 involved_in IEA UniProt
Ensembl		 GO_REF:0000104 GO_REF:0000107 NCBI chrNW_004936493:5,731,106...5,747,270
Ensembl chrNW_004936493:5,731,058...5,760,987 		JBrowse link
G Tmem14a transmembrane protein 14A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:8,179,949...8,198,204
Ensembl chrNW_004936476:8,180,141...8,185,884 		JBrowse link
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19096392) Ensembl
MGI		 PMID:19096392 GO_REF:0000107 NCBI chrNW_004936474:12,396,416...12,399,760
Ensembl chrNW_004936474:12,396,023...12,401,023 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936745:344,837...350,950
Ensembl chrNW_004936745:345,635...351,749 		JBrowse link
G Chchd10 coiled-coil-helix-coiled-coil-helix domain containing 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936619:1,323,247...1,325,520
Ensembl chrNW_004936619:1,323,246...1,325,522 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936706:266,462...277,256
Ensembl chrNW_004936706:269,126...277,256 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISO (MGI:5514334|PMID:16543145) UniProt PMID:16543145 MGI:5514334 NCBI chrNW_004936536:6,730,070...6,893,818
Ensembl chrNW_004936536:6,730,062...6,894,303 		JBrowse link
G Hip1r huntingtin interacting protein 1 related involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936558:1,778,862...1,804,071
Ensembl chrNW_004936558:1,778,888...1,791,610 		JBrowse link
G Siva1 SIVA1 apoptosis inducing factor involved_in ISO (PMID:15034012) BHF-UCL PMID:15034012 NCBI chrNW_004936621:641,456...650,067
Ensembl chrNW_004936621:644,852...650,132 		JBrowse link
G Znf205 zinc finger protein 205 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936694:1,072,633...1,084,923
Ensembl chrNW_004936694:1,072,653...1,081,755 		JBrowse link
regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:6,479,640...6,486,080
Ensembl chrNW_004936474:6,477,504...6,486,660 		JBrowse link
G Tmem102 transmembrane protein 102 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936595:718,513...720,553
Ensembl chrNW_004936595:718,923...720,553 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15871
    cellular process 15001
      cell death 1877
        programmed cell death 1877
          mitochondrial outer membrane permeabilization involved in programmed cell death 38
            positive regulation of mitochondrial membrane permeability involved in apoptotic process 36
              mitochondrial outer membrane permeabilization + 32
Path 2
Term Annotations click to browse term
  biological_process 15871
    cellular process 15001
      cellular component organization or biogenesis 6443
        cellular component organization 6231
          organelle organization 3482
            mitochondrion organization 503
              mitochondrial membrane organization 110
                regulation of mitochondrial membrane permeability 56
                  positive regulation of mitochondrial membrane permeability 41
                    mitochondrial outer membrane permeabilization involved in programmed cell death 38
                      positive regulation of mitochondrial membrane permeability involved in apoptotic process 36
                        mitochondrial outer membrane permeabilization + 32
paths to the root