Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of metaphase/anaphase transition of cell cycle
go back to main search page
Accession:GO:1902100 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of cell cycle.
Synonyms:exact_synonym: down regulation of metaphase/anaphase transition of cell cycle;   downregulation of metaphase/anaphase transition of cell cycle
 narrow_synonym: inhibition of metaphase/anaphase transition of cell cycle



show annotations for term's descendants           Sort by:
deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mad1l1 mitotic arrest deficient 1 like 1 involved_in ISO (PMID:19010891) RGD PMID:19010891 NCBI chr12:14,320,892...14,630,750
Ensembl chr12:14,320,892...14,630,703
JBrowse link
G Mad2l1bp MAD2L1 binding protein involved_in ISO (PMID:18022368) RGD PMID:18022368 NCBI chr 9:14,832,133...14,836,458
Ensembl chr 9:14,832,132...14,837,447
JBrowse link
G Prap1 proline-rich acidic protein 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:24374861)
UniProt
RGD
PMID:24374861 GO_REF:0000024 NCBI chr 1:194,883,078...194,886,874
Ensembl chr 1:194,883,078...194,886,872
JBrowse link
meiotic spindle assembly checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ttk Ttk protein kinase involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:5056148 (PMID:21558374)
GO_Central
RGD
PMID:21558374 GO_REF:0000033 NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651
JBrowse link
meiotic spindle checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chfr checkpoint with forkhead and ring finger domains involved_in ISO (PMID:10935642) RGD PMID:10935642 NCBI chr12:46,504,497...46,538,104
Ensembl chr12:46,504,497...46,538,014
JBrowse link
mitotic spindle assembly checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:17227893)
GO_REF:0000107
RGD
Ensembl
PMID:17227893 GO_REF:0000107 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G Atm ATM serine/threonine kinase involved_in ISO (PMID:11943150) RGD PMID:11943150 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 involved_in ISO
ISS
(PMID:12805209)
GO_REF:0000024
RGD
UniProt
PMID:12805209 GO_REF:0000024 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase involved_in ISO
IBA
(PMID:18995837)
GO_REF:0000033
RGD
GO_Central
PMID:18995837 GO_REF:0000033 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B involved_in ISO
IBA
(PMID:10477750), (PMID:20220147)
GO_REF:0000033
RGD
GO_Central
PMID:10477750 PMID:20220147 GO_REF:0000033 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
JBrowse link
G Bub3 BUB3 mitotic checkpoint protein involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 1:186,330,358...186,340,969
Ensembl chr 1:186,327,931...186,395,036
JBrowse link
G Cenpe centromere protein E involved_in ISO (MGI:2673075|PMID:12925705) RGD PMID:12925705 MGI:2673075 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
JBrowse link
G Haspin histone H3 associated protein kinase involved_in ISO (PMID:23071153) RGD PMID:23071153 NCBI chr10:57,747,731...57,750,518
Ensembl chr10:57,747,573...57,750,512
JBrowse link
G Ik IK cytokine involved_in ISS
ISO
GO_REF:0000024
(PMID:22351768)
UniProt
RGD
PMID:22351768 GO_REF:0000024 NCBI chr18:28,358,004...28,372,809
Ensembl chr18:28,357,977...28,378,832
JBrowse link
G Khdc3 KH domain containing 3, subcortical maternal complex member acts_upstream_of_or_within ISO MGI:3844604 (PMID:19376971) RGD PMID:19376971 NCBI chr 8:73,842,344...73,844,248
Ensembl chr 8:73,842,344...73,844,248
JBrowse link
G Klhl22 kelch-like family member 22 involved_in ISS
ISO
GO_REF:0000024
(PMID:23455478)
UniProt
RGD
PMID:23455478 GO_REF:0000024 NCBI chr11:83,190,891...83,231,746
Ensembl chr11:83,190,891...83,231,770
JBrowse link
G Kntc1 kinetochore associated 1 involved_in ISO
IBA
(PMID:11146660)
GO_REF:0000033
RGD
GO_Central
PMID:11146660 GO_REF:0000033 NCBI chr12:32,769,020...32,839,617
Ensembl chr12:32,769,020...32,839,561
JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 involved_in ISO
IBA
(PMID:18981471), (PMID:36322655), (PMID:9546394)
GO_REF:0000033
RGD
GO_Central
PMID:9546394 PMID:18981471 PMID:36322655 GO_REF:0000033 NCBI chr12:14,320,892...14,630,750
Ensembl chr12:14,320,892...14,630,703
JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:18981471)
MGI:2178781 (PMID:11201745)
GO_REF:0000033
RGD
GO_Central
PMID:11201745 PMID:18981471 GO_REF:0000033 NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470
JBrowse link
G Plk1 polo-like kinase 1 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:23455478)
Ensembl
UniProt
RGD
PMID:23455478 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
JBrowse link
G Psmg2 proteasome assembly chaperone 2 acts_upstream_of_or_within ISO (PMID:12147697) RGD PMID:12147697 NCBI chr18:61,208,669...61,227,671
Ensembl chr18:61,208,678...61,259,816
JBrowse link
G Spdl1 spindle apparatus coiled-coil protein 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:19,269,125...19,294,213
Ensembl chr10:19,269,127...19,294,127
JBrowse link
G Tex14 testis expressed 14, intercellular bridge forming factor involved_in IEA
IBA
ISO
ISS
GO_REF:0000107
GO_REF:0000033
GO_REF:0000118
GO_REF:0000002
(MGI:5318128|PMID:22405274)
GO_REF:0000024
Ensembl
GO_Central
TreeGrafter
InterPro
RGD
UniProt
PMID:22405274 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:5318128 NCBI chr10:72,231,766...72,356,938
Ensembl chr10:72,231,801...72,355,805
JBrowse link
G Tpr translocated promoter region, nuclear basket protein involved_in ISO
IEA
ISS
(PMID:20133940)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:20133940 GO_REF:0000024 GO_REF:0000107 NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496
JBrowse link
G Trip13 thyroid hormone receptor interactor 13 involved_in ISO
ISS
(PMID:28553959)
GO_REF:0000024
RGD
UniProt
PMID:28553959 GO_REF:0000024 NCBI chr 1:29,357,093...29,402,078
Ensembl chr 1:29,357,130...29,402,074
JBrowse link
G Ttk Ttk protein kinase involved_in IBA
ISO
GO_REF:0000033
MGI:5056148 (PMID:25197064)
GO_Central
RGD
PMID:25197064 GO_REF:0000033 NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651
JBrowse link
G Zfp207 zinc finger protein 207 involved_in ISO (PMID:24462186), (PMID:24462187) RGD PMID:24462186 PMID:24462187 NCBI chr10:65,385,807...65,398,086
Ensembl chr10:65,385,740...65,397,386
JBrowse link
G Zw10 zw10 kinetochore protein involved_in ISS
IBA
ISO
GO_REF:0000024
GO_REF:0000033
(PMID:11146660), (PMID:15824131)
HGNC-UCL
GO_Central
RGD
PMID:11146660 PMID:15824131 GO_REF:0000024 GO_REF:0000033 NCBI chr 8:49,396,541...49,424,743
Ensembl chr 8:49,396,545...49,421,805
JBrowse link
G Zwilch zwilch kinetochore protein involved_in ISO
IBA
(PMID:15824131)
GO_REF:0000033
RGD
GO_Central
PMID:15824131 GO_REF:0000033 NCBI chr 8:64,638,401...64,670,911
Ensembl chr 8:64,637,672...64,675,916
JBrowse link
G Zwint ZW10 interacting kinetochore protein involved_in ISO
IBA
(PMID:15485811)
GO_REF:0000033
RGD
GO_Central
PMID:15485811 GO_REF:0000033 NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957
JBrowse link
negative regulation of metaphase/anaphase transition of meiotic cell cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mos MOS proto-oncogene, serine/threonine kinase involved_in ISS
IEA
ISO
IBA
GO_REF:0000024
GO_REF:0000107
(PMID:12533425)
(MGI:67285|PMID:8015610), (MGI:67286|PMID:8015609)
GO_REF:0000033
UniProt
Ensembl
RGD
GO_Central
PMID:8015609 PMID:8015610 PMID:12533425 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:67285 MGI:67286 NCBI chr 5:16,859,957...16,861,264
Ensembl chr 5:16,859,957...16,861,264
JBrowse link
negative regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo5 F-box protein 5 involved_in ISO (PMID:11988738), (PMID:16921029) RGD PMID:11988738 PMID:16921029 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437
JBrowse link
G Rad21 RAD21 cohesin complex component involved_in ISO (MGI:1340883|PMID:10375619) RGD PMID:10375619 MGI:1340883 NCBI chr 7:83,287,867...83,314,810
Ensembl chr 7:83,287,870...83,314,817
JBrowse link
G Usp44 ubiquitin specific peptidase 44 involved_in ISO (PMID:17443180) RGD PMID:17443180 NCBI chr 7:28,364,169...28,412,039
Ensembl chr 7:28,364,033...28,410,053
JBrowse link
positive regulation of meiosis I spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Knl1 kinetochore scaffold 1 involved_in ISO (MGI:7356173|PMID:35167144) RGD PMID:35167144 MGI:7356173 NCBI chr 3:106,029,627...106,091,915
Ensembl chr 3:106,029,661...106,091,915
JBrowse link
positive regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:19229290)
UniProt
Ensembl
RGD
PMID:19229290 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:114,376,649...114,410,297
Ensembl chr 8:114,376,662...114,410,934
JBrowse link
G Gen1 GEN1 Holliday junction 5' flap endonuclease involved_in ISO (PMID:23108668) RGD PMID:23108668 NCBI chr 6:33,947,599...33,978,461
Ensembl chr 6:33,948,206...33,978,401
JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 involved_in ISO (PMID:22898774), (PMID:36322655) RGD PMID:22898774 PMID:36322655 NCBI chr12:14,320,892...14,630,750
Ensembl chr12:14,320,892...14,630,703
JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 involved_in ISO (MGI:4839685|PMID:20870947)
(PMID:20870947), (PMID:22898774), (PMID:8824189)
RGD PMID:8824189 PMID:20870947 PMID:22898774 MGI:4839685 NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470
JBrowse link
G Ndc80 NDC80 kinetochore complex component involved_in ISO (PMID:25743205) RGD PMID:25743205 NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924
JBrowse link
G Pcid2 PCI domain containing 2 involved_in ISO (PMID:20870947)
(MGI:4839685|PMID:20870947)
RGD PMID:20870947 MGI:4839685 NCBI chr16:76,423,245...76,448,712
Ensembl chr16:76,423,245...76,448,712
JBrowse link
G Tpr translocated promoter region, nuclear basket protein involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:18981471), (PMID:19273613)
UniProt
Ensembl
RGD
PMID:18981471 PMID:19273613 GO_REF:0000024 GO_REF:0000107 NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 involved_in ISO (PMID:23108668) RGD PMID:23108668 NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444
JBrowse link
regulation of meiosis I spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zwint ZW10 interacting kinetochore protein involved_in ISS
ISO
GO_REF:0000024
(MGI:6215447|PMID:26486467)
UniProt
RGD
PMID:26486467 GO_REF:0000024 MGI:6215447 NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957
JBrowse link
regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anapc15 anaphase promoting complex subunit 15 involved_in ISO
IEA
IBA
ISS
(PMID:21926987)
GO_REF:0000118
GO_REF:0000033
GO_REF:0000002
GO_REF:0000024
RGD
TreeGrafter
GO_Central
InterPro
UniProt
PMID:21926987 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:156,238,640...156,266,005
Ensembl chr 1:156,262,841...156,268,145
JBrowse link
G Ccnb1 cyclin B1 involved_in ISO
IEA
(PMID:18195732)
GO_REF:0000107
RGD
Ensembl
PMID:18195732 GO_REF:0000107 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 involved_in ISS
IBA
IEA
ISO
GO_REF:0000024
GO_REF:0000033
GO_REF:0000118
(PMID:19282672)
GO_REF:0000107
UniProt
GO_Central
TreeGrafter
RGD
Ensembl
PMID:19282672 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:83,792,282...83,961,129
Ensembl chr 5:83,792,284...83,960,782
JBrowse link
G Dusp1 dual specificity phosphatase 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Knl1 kinetochore scaffold 1 involved_in ISO (PMID:19893618) RGD PMID:19893618 NCBI chr 3:106,029,627...106,091,915
Ensembl chr 3:106,029,661...106,091,915
JBrowse link
G Lcmt1 leucine carboxyl methyltransferase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:17724024)
GO_REF:0000107
RGD
Ensembl
PMID:17724024 GO_REF:0000107 NCBI chr 1:177,904,119...177,960,111
Ensembl chr 1:177,904,139...177,960,112
JBrowse link
G Prpf4b pre-mRNA processing factor 4B involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:17998396)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:17998396 GO_REF:0000024 GO_REF:0000107 NCBI chr17:29,985,343...30,020,285
Ensembl chr17:29,985,343...30,019,625
JBrowse link
G Usp44 ubiquitin specific peptidase 44 involved_in ISO (MGI:5448515|PMID:21853124) RGD PMID:21853124 MGI:5448515 NCBI chr 7:28,364,169...28,412,039
Ensembl chr 7:28,364,033...28,410,053
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    cellular process 18769
      cell cycle process 1343
        negative regulation of cell cycle process 316
          negative regulation of cell cycle phase transition 266
            negative regulation of metaphase/anaphase transition of cell cycle 44
              negative regulation of metaphase/anaphase transition of meiotic cell cycle + 5
              negative regulation of mitotic metaphase/anaphase transition + 42
Path 2
Term Annotations click to browse term
  biological_process 20292
    cellular process 18769
      cell cycle 1679
        cell cycle process 1343
          chromosome segregation 406
            nuclear chromosome segregation 306
              sister chromatid segregation 201
                regulation of sister chromatid segregation 74
                  metaphase/anaphase transition of cell cycle 65
                    regulation of metaphase/anaphase transition of cell cycle 60
                      negative regulation of metaphase/anaphase transition of cell cycle 44
                        negative regulation of metaphase/anaphase transition of meiotic cell cycle + 5
                        negative regulation of mitotic metaphase/anaphase transition + 42
paths to the root