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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of hypoxia-inducible factor-1alpha signaling pathway
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Accession:GO:1902072 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.
Synonyms:exact_synonym: down regulation of HIF1alpha pathway;   down regulation of hypoxia-inducible factor-1alpha signaling pathway;   down regulation of hypoxia-inducible factor-1alpha signalling pathway;   downregulation of HIF1alpha pathway;   downregulation of hypoxia-inducible factor-1alpha signaling pathway;   downregulation of hypoxia-inducible factor-1alpha signalling pathway;   inhibition of HIF1alpha pathway;   inhibition of hypoxia-inducible factor-1alpha signalling pathway;   negative regulation of HIF1alpha pathway;   negative regulation of hypoxia-inducible factor-1alpha signalling pathway
 narrow_synonym: inhibition of hypoxia-inducible factor-1alpha signaling pathway


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negative regulation of hypoxia-inducible factor-1alpha signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Commd1 copper metabolism domain containing 1 ISO MGI:MGI:3714157 (MGI:MGI:3713589|PMID:17371845) RGD PMID:17371845 MGI:MGI:3713589 NCBI chr14:107,664,321...107,759,974
Ensembl chr14:107,664,255...107,760,191
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor ISO MGI:MGI:2136645|MGI:MGI:3608931 (MGI:MGI:5618205|PMID:25186293) RGD PMID:25186293 MGI:MGI:5618205 NCBI chr 4:145,580,869...145,587,835
Ensembl chr 4:145,580,799...145,587,845
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    cellular process 18788
      signal transduction 7015
        negative regulation of signal transduction 1243
          negative regulation of hypoxia-inducible factor-1alpha signaling pathway 2
Path 2
Term Annotations click to browse term
  biological_process 20014
    response to stimulus 10568
      response to abiotic stimulus 1506
        response to oxygen levels 534
          response to decreased oxygen levels 468
            response to hypoxia 436
              cellular response to hypoxia 182
                regulation of cellular response to hypoxia 18
                  negative regulation of cellular response to hypoxia 11
                    negative regulation of hypoxia-inducible factor-1alpha signaling pathway 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.