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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of hypoxia-inducible factor-1alpha signaling pathway
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Accession:GO:1902071 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.
Synonyms:exact_synonym: regulation of HIF1alpha pathway;   regulation of hypoxia-inducible factor-1alpha signalling pathway


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negative regulation of hypoxia-inducible factor-1alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Commd1 copper metabolism domain containing 1 acts_upstream_of_or_within ISO MGI:3714157 (MGI:3713589|PMID:17371845) RGD PMID:17371845 MGI:3713589 NCBI chr14:107,664,321...107,759,974
Ensembl chr14:107,664,255...107,760,191
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor acts_upstream_of_or_within ISO MGI:2136645|MGI:3608931 (MGI:5618205|PMID:25186293) RGD PMID:25186293 MGI:5618205 NCBI chr 4:145,580,869...145,587,835
Ensembl chr 4:145,580,799...145,587,845
JBrowse link
positive regulation of hypoxia-inducible factor-1alpha signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rwdd3 RWD domain containing 3 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:23469069)
(MGI:5569907|PMID:22009797)
UniProt
RGD
PMID:22009797 PMID:23469069 GO_REF:0000024 MGI:5569907 NCBI chr 2:224,710,351...224,723,136
Ensembl chr 2:224,710,348...224,723,112
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    cellular process 18457
      signal transduction 6956
        regulation of signal transduction 2964
          regulation of hypoxia-inducible factor-1alpha signaling pathway 3
            negative regulation of hypoxia-inducible factor-1alpha signaling pathway 2
            positive regulation of hypoxia-inducible factor-1alpha signaling pathway 1
Path 2
Term Annotations click to browse term
  biological_process 19612
    response to stimulus 10435
      cellular response to stimulus 8799
        cellular response to chemical stimulus 3521
          cellular response to oxygen levels 230
            cellular response to decreased oxygen levels 208
              cellular response to hypoxia 180
                hypoxia-inducible factor-1alpha signaling pathway 7
                  regulation of hypoxia-inducible factor-1alpha signaling pathway 3
                    negative regulation of hypoxia-inducible factor-1alpha signaling pathway 2
                    positive regulation of hypoxia-inducible factor-1alpha signaling pathway 1
paths to the root