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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cell cycle checkpoint
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Accession:GO:1901977 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle checkpoint.
Comment:Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of checkpoint (i.e mitotic spindle or DNA damage etc).
Synonyms:exact_synonym: down regulation of cell cycle checkpoint;   downregulation of cell cycle checkpoint
 narrow_synonym: inhibition of cell cycle checkpoint
 related_synonym: negative regulation of G1/S checkpoint;   negative regulation of G1/S transition checkpoint
 alt_id: GO:2001048



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deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:22581055) RGD PMID:22581055 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 involved_in ISO (PMID:19010891) RGD PMID:19010891 NCBI chr12:14,320,892...14,630,750
Ensembl chr12:14,320,892...14,630,703
JBrowse link
G Mad2l1bp MAD2L1 binding protein involved_in ISO (PMID:18022368) RGD PMID:18022368 NCBI chr 9:14,832,133...14,836,458
Ensembl chr 9:14,832,132...14,837,447
JBrowse link
G Prap1 proline-rich acidic protein 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:24374861)
UniProt
RGD
PMID:24374861 GO_REF:0000024 NCBI chr 1:194,883,078...194,886,874
Ensembl chr 1:194,883,078...194,886,872
JBrowse link
negative regulation of DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brd4 bromodomain containing 4 involved_in ISO (PMID:23728299) RGD PMID:23728299 NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539
JBrowse link
G Chek2 checkpoint kinase 2 IMP RGD PMID:20637979 RGD:10401658 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Da2-19 uncharacterized LOC302729 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr  X:44,820,693...44,837,935
Ensembl chr  X:44,820,820...44,837,934
JBrowse link
G Ddx39b DExD-box helicase 39B involved_in ISS
ISO
GO_REF:0000024
(PMID:22144908)
UniProt
RGD
PMID:22144908 GO_REF:0000024 NCBI chr20:3,547,702...3,585,064
Ensembl chr20:3,572,056...3,584,996
JBrowse link
G Thoc1 THO complex 1 involved_in ISO (PMID:22144908) RGD PMID:22144908 NCBI chr18:983,606...1,020,379
Ensembl chr18:983,824...1,019,114
JBrowse link
G Thoc5 THO complex 5 involved_in ISS
ISO
GO_REF:0000024
(PMID:22144908)
UniProt
RGD
PMID:22144908 GO_REF:0000024 NCBI chr14:79,758,805...79,792,718
Ensembl chr14:79,758,917...79,792,718
JBrowse link
negative regulation of mitotic DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 involved_in ISO UniProtKB:Q15554 (PMID:23426265) RGD PMID:23426265 NCBI chr20:2,822,995...2,838,125
Ensembl chr20:2,822,995...2,837,611
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19512
    cellular process 18319
      signal transduction 6952
        intracellular signal transduction 2643
          cell cycle checkpoint signaling 174
            negative regulation of cell cycle checkpoint 11
              negative regulation of DNA damage checkpoint + 7
              negative regulation of spindle checkpoint + 4
Path 2
Term Annotations click to browse term
  biological_process 19512
    biological regulation 13616
      regulation of biological process 12887
        regulation of cellular process 12364
          regulation of cell cycle 1066
            regulation of cell cycle process 702
              negative regulation of cell cycle process 290
                negative regulation of cell cycle phase transition 242
                  cell cycle checkpoint signaling 174
                    regulation of cell cycle checkpoint 37
                      negative regulation of cell cycle checkpoint 11
                        negative regulation of DNA damage checkpoint + 7
                        negative regulation of spindle checkpoint + 4
paths to the root