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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of protein depolymerization
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Accession:GO:1901881 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of protein depolymerization.
Synonyms:exact_synonym: activation of protein polymer breakdown;   activation of protein polymer catabolic process;   activation of protein polymer catabolism;   activation of protein polymer degradation;   positive regulation of protein polymer breakdown;   positive regulation of protein polymer catabolic process;   positive regulation of protein polymer catabolism;   positive regulation of protein polymer degradation;   up regulation of protein depolymerization;   up regulation of protein polymer breakdown;   up regulation of protein polymer catabolic process;   up regulation of protein polymer catabolism;   up regulation of protein polymer degradation;   upregulation of protein depolymerization;   upregulation of protein polymer breakdown;   upregulation of protein polymer catabolic process;   upregulation of protein polymer catabolism;   upregulation of protein polymer degradation
 narrow_synonym: activation of protein depolymerization



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actin filament uncapping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn2 actinin alpha 2 involved_in ISO (PMID:25433700) RGD PMID:25433700 NCBI chr17:58,143,334...58,210,622
Ensembl chr17:58,142,625...58,210,622
JBrowse link
barbed-end actin filament uncapping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil1 capping protein regulator and myosin 1 linker 1 involved_in ISO (MGI:3588909|PMID:16054028) RGD PMID:16054028 MGI:3588909 NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326
JBrowse link
negative regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil1 capping protein regulator and myosin 1 linker 1 involved_in ISO (MGI:3588909|PMID:16054028) RGD PMID:16054028 MGI:3588909 NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326
JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 involved_in ISO (PMID:26466680) RGD PMID:26466680 NCBI chr19:33,571,255...33,586,783
Ensembl chr19:33,574,257...33,586,965
JBrowse link
G Cracd capping protein inhibiting regulator of actin dynamics involved_in ISO
IBA
(PMID:30361697)
PMID:21873635
RGD PMID:30361697 PMID:21873635 RGD:13792537 NCBI chr14:31,284,066...31,520,103
Ensembl chr14:31,284,184...31,522,431
JBrowse link
G Washc2c WASH complex subunit 2C involved_in ISO (PMID:20498093) RGD PMID:20498093 NCBI chr 4:149,267,851...149,325,850
Ensembl chr 4:149,267,924...149,325,851
JBrowse link
positive regulation of actin filament depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfl1 cofilin 1 involved_in
acts_upstream_of_or_within
ISO (MGI:5554982|PMID:23921380)
(MGI:3575233|PMID:15548599)
RGD PMID:15548599 PMID:23921380 MGI:3575233 MGI:5554982 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
JBrowse link
G Cfl2 cofilin 2 involved_in ISO (PMID:17160903) RGD PMID:17160903 NCBI chr 6:72,355,664...72,359,709
Ensembl chr 6:72,355,664...72,359,674
JBrowse link
G Dstn destrin, actin depolymerizing factor acts_upstream_of_or_within ISO (MGI:3575233|PMID:15548599) RGD PMID:15548599 MGI:3575233 NCBI chr 3:131,284,647...131,311,361
Ensembl chr 3:131,284,648...131,311,379
JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:17500066) RGD PMID:17500066 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
JBrowse link
G Pdxp pyridoxal phosphatase involved_in ISO
ISS
IEA
(PMID:15580268)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:15580268 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:110,472,515...110,477,963
Ensembl chr 7:110,472,515...110,477,963
JBrowse link
G Plek pleckstrin involved_in ISO
IEA
(PMID:10497244)
GO_REF:0000107
(MGI:3844782|PMID:19190246)
RGD
Ensembl
PMID:10497244 PMID:19190246 GO_REF:0000107 MGI:3844782 NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131
JBrowse link
G Sema5a semaphorin 5A involved_in ISS
ISO
GO_REF:0000024
(MGI:5526935|PMID:19850054)
UniProt
RGD
PMID:19850054 GO_REF:0000024 MGI:5526935 NCBI chr 2:83,309,843...83,741,084
Ensembl chr 2:83,309,843...83,741,084
JBrowse link
G Vil1 villin 1 involved_in ISO (PMID:15272027) RGD PMID:15272027 NCBI chr 9:75,991,141...76,018,860
Ensembl chr 9:75,991,141...76,018,858
JBrowse link
G Wdr1 WD repeat domain 1 acts_upstream_of_or_within ISO MGI:101763 (MGI:5574550|PMID:24840128) RGD PMID:24840128 MGI:5574550 NCBI chr14:72,258,032...72,291,768
Ensembl chr14:72,257,956...72,291,766
JBrowse link
positive regulation of intermediate filament depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nes nestin involved_in IDA
IBA
PMID:12686602
PMID:21873635
UniProt
GO_Central
PMID:12686602 PMID:21873635 RGD:633505, RGD:13792537 NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777
JBrowse link
positive regulation of microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1a 5-hydroxytryptamine receptor 1A IDA RGD PMID:18442977 RGD:7241017 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442
JBrowse link
G Katnb1 katanin regulatory subunit B1 involved_in ISO (PMID:10751153) RGD PMID:10751153 NCBI chr19:9,921,216...9,940,853
Ensembl chr19:9,921,219...9,940,650
JBrowse link
G Spast spastin involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 6:21,055,349...21,106,586
Ensembl chr 6:21,055,349...21,107,954
JBrowse link
G Stmn2 stathmin 2 involved_in ISO
IEA
(PMID:18452648)
GO_REF:0000107
RGD
Ensembl
PMID:18452648 GO_REF:0000107 NCBI chr 2:93,204,690...93,252,011
Ensembl chr 2:93,204,692...93,252,011
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 involved_in IDA PMID:20657843 BHF-UCL PMID:20657843 RGD:8553293 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19553
    positive regulation of biological process 6613
      positive regulation of cellular process 6122
        positive regulation of cellular component organization 1303
          positive regulation of protein-containing complex disassembly 39
            positive regulation of protein depolymerization 20
              positive regulation of actin filament depolymerization + 14
              positive regulation of intermediate filament depolymerization 1
              positive regulation of microtubule depolymerization 5
              positive regulation of synaptic vesicle uncoating 0
Path 2
Term Annotations click to browse term
  biological_process 19553
    cellular process 18233
      cellular component organization or biogenesis 6802
        cellular component organization 6536
          cellular component disassembly 501
            protein-containing complex disassembly 266
              regulation of protein-containing complex disassembly 138
                regulation of protein depolymerization 100
                  positive regulation of protein depolymerization 20
                    positive regulation of actin filament depolymerization + 14
                    positive regulation of intermediate filament depolymerization 1
                    positive regulation of microtubule depolymerization 5
                    positive regulation of synaptic vesicle uncoating 0
paths to the root