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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of protein depolymerization
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Accession:GO:1901880 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization.
Synonyms:exact_synonym: down regulation of protein depolymerization;   down regulation of protein polymer breakdown;   down regulation of protein polymer catabolic process;   down regulation of protein polymer catabolism;   down regulation of protein polymer degradation;   downregulation of protein depolymerization;   downregulation of protein polymer breakdown;   downregulation of protein polymer catabolic process;   downregulation of protein polymer catabolism;   downregulation of protein polymer degradation;   inhibition of protein polymer breakdown;   inhibition of protein polymer catabolic process;   inhibition of protein polymer catabolism;   inhibition of protein polymer degradation;   negative regulation of protein polymer breakdown;   negative regulation of protein polymer catabolic process;   negative regulation of protein polymer catabolism;   negative regulation of protein polymer degradation
 narrow_synonym: inhibition of protein depolymerization

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actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsn gelsolin involved_in ISO (PMID:19666531)
(MGI:5619440|PMID:23325791)		 UniProt PMID:19666531 PMID:23325791 MGI:5619440 NCBI chrNW_004955419:6,682,202...6,733,361
Ensembl chrNW_004955419:6,682,058...6,733,361 		JBrowse link
G Myh9 myosin heavy chain 9 NOT|involved_in ISO (MGI:5619440|PMID:23325791) UniProt PMID:23325791 MGI:5619440 NCBI chrNW_004955413:22,881,759...22,972,182
Ensembl chrNW_004955413:22,881,045...22,972,450 		JBrowse link
G Scin scinderin involved_in ISO (PMID:19666531) UniProt PMID:19666531 NCBI chrNW_004955410:16,286,131...16,358,286
Ensembl chrNW_004955410:16,285,217...16,358,280 		JBrowse link
G Tpm1 tropomyosin 1 ISO RGD PMID:15779917 RGD:1600523 NCBI chrNW_004955450:12,197,241...12,223,372
Ensembl chrNW_004955450:12,194,755...12,224,011 		JBrowse link
G Vil1 villin 1 involved_in ISO (PMID:16921170), (PMID:17182858), (PMID:19808673) UniProt PMID:16921170 PMID:17182858 PMID:19808673 NCBI chrNW_004955453:14,935,450...14,961,011
Ensembl chrNW_004955453:14,935,456...14,961,011 		JBrowse link
barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Add1 adducin 1 involved_in ISO (PMID:8626479) BHF-UCL PMID:8626479 NCBI chrNW_004955514:1,784,302...1,812,845
Ensembl chrNW_004955514:1,783,814...1,815,917 		JBrowse link
G Add2 adducin 2 involved_in ISO (PMID:8626479) BHF-UCL PMID:8626479 NCBI chrNW_004955424:14,411,279...14,517,813
Ensembl chrNW_004955424:14,411,124...14,517,813 		JBrowse link
G Capza1 capping actin protein of muscle Z-line subunit alpha 1 acts_upstream_of_or_within ISO (PMID:17656356) MGI PMID:17656356 NCBI chrNW_004955435:16,048,213...16,087,814
Ensembl chrNW_004955435:16,048,213...16,087,814 		JBrowse link
G Dbnl drebrin like NOT|acts_upstream_of_or_within ISO (PMID:10637315) MGI PMID:10637315 NCBI chrNW_004955456:7,912,827...7,924,373
Ensembl chrNW_004955456:7,912,827...7,924,787 		JBrowse link
G Eps8 EGFR pathway substrate 8, signaling adaptor involved_in ISO (MGI:4460022|PMID:20532239), (MGI:5486559|PMID:15558031)
(MGI:5476881|PMID:23314863)		 UniProt PMID:15558031 PMID:20532239 PMID:23314863 MGI:4460022 MGI:5476881 MGI:5486559 NCBI chrNW_004955413:12,267,701...12,386,088
Ensembl chrNW_004955413:12,266,371...12,386,088 		JBrowse link
G Rdx radixin ISO RGD PMID:2500445 RGD:8693627 NCBI chrNW_004955412:12,100,436...12,184,444
Ensembl chrNW_004955412:12,100,359...12,172,545 		JBrowse link
G Twf1 twinfilin actin binding protein 1 involved_in ISO (MGI:3840765|PMID:18837697) BHF-UCL PMID:18837697 MGI:3840765 NCBI chrNW_004955500:3,050,028...3,070,799 JBrowse link
G Twf2 twinfilin actin binding protein 2 involved_in ISO (MGI:3840765|PMID:18837697) BHF-UCL PMID:18837697 MGI:3840765 NCBI chrNW_004955532:3,835,620...3,844,760
Ensembl chrNW_004955532:3,834,579...3,844,760 		JBrowse link
G Vil1 villin 1 involved_in ISO (PMID:15272027) UniProt PMID:15272027 NCBI chrNW_004955453:14,935,450...14,961,011
Ensembl chrNW_004955453:14,935,456...14,961,011 		JBrowse link
negative regulation of actin filament depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfl1 cofilin 1 ISO RGD PMID:15252126 RGD:2306210 NCBI chrNW_004955422:19,479,181...19,482,571
Ensembl chrNW_004955422:19,479,181...19,482,571 		JBrowse link
G Lima1 LIM domain and actin binding 1 involved_in ISO (PMID:12566430) UniProt PMID:12566430 NCBI chrNW_004955547:730,152...827,644
Ensembl chrNW_004955547:730,073...827,783 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha involved_in ISO (MGI:6450443|PMID:30568254) BHF-UCL PMID:30568254 MGI:6450443 NCBI chrNW_004955420:8,355,415...8,427,024
Ensembl chrNW_004955420:8,356,353...8,427,024 		JBrowse link
G Plekhh2 pleckstrin homology, MyTH4 and FERM domain containing H2 involved_in ISO (MGI:5487756|PMID:22832517) UniProt PMID:22832517 MGI:5487756 NCBI chrNW_004955441:10,818,982...10,921,224
Ensembl chrNW_004955441:10,825,499...10,919,901 		JBrowse link
G Shroom2 shroom family member 2 acts_upstream_of_or_within ISO (PMID:17666436) MGI PMID:17666436 NCBI chrNW_004955499:8,031,961...8,103,307
Ensembl chrNW_004955499:8,031,615...8,100,952 		JBrowse link
G Specc1l sperm antigen with calponin homology and coiled-coil domains 1 like acts_upstream_of_or_within ISO (PMID:21703590) MGI PMID:21703590 NCBI chrNW_004955455:7,739,105...7,879,489
Ensembl chrNW_004955455:7,739,463...7,882,427 		JBrowse link
G Swap70 switching B cell complex subunit SWAP70 involved_in ISO (MGI:5554982|PMID:23921380) CACAO PMID:23921380 MGI:5554982 NCBI chrNW_004955414:25,385,648...25,444,743
Ensembl chrNW_004955414:25,385,007...25,444,913 		JBrowse link
negative regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil1 capping protein regulator and myosin 1 linker 1 involved_in ISO (MGI:3588909|PMID:16054028) UniProt PMID:16054028 MGI:3588909 NCBI chrNW_004955483:1,463,856...1,770,798
Ensembl chrNW_004955483:1,463,805...1,770,520 		JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 involved_in ISO (PMID:26466680) UniProt PMID:26466680 NCBI chrNW_004955484:9,025,409...9,037,942
Ensembl chrNW_004955484:9,025,460...9,037,580 		JBrowse link
G Cracd capping protein inhibiting regulator of actin dynamics involved_in ISO (PMID:30361697) UniProt PMID:30361697 NCBI chrNW_004955447:14,650,035...14,672,593 JBrowse link
G Washc2c WASH complex subunit 2C involved_in ISO (PMID:20498093) UniProt PMID:20498093 NCBI chrNW_004955546:2,718,758...2,764,277 JBrowse link
negative regulation of microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway involved_in
acts_upstream_of_or_within		 ISO (PMID:11166179)
(PMID:16525027)
(PMID:17192415)		 UniProt
MGI		 PMID:11166179 PMID:16525027 PMID:17192415 NCBI chrNW_004955418:2,567,804...2,675,062
Ensembl chrNW_004955418:2,566,975...2,674,832 		JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:11912491) UniProt PMID:11912491 NCBI chrNW_004955545:2,149,107...2,192,986
Ensembl chrNW_004955545:2,149,107...2,197,153 		JBrowse link
G Atxn7 ataxin 7 involved_in ISO (PMID:22100762) CACAO PMID:22100762 NCBI chrNW_004955517:1,897,050...1,980,428
Ensembl chrNW_004955517:1,892,757...1,980,524 		JBrowse link
G Bmerb1 bMERB domain containing 1 acts_upstream_of_or_within ISO (PMID:25099998) MGI PMID:25099998 NCBI chrNW_004955442:317,334...442,514
Ensembl chrNW_004955442:314,486...442,088 		JBrowse link
G Cib1 calcium and integrin binding 1 involved_in ISO (PMID:21215777) UniProt PMID:21215777 NCBI chrNW_004955416:15,102,632...15,106,372
Ensembl chrNW_004955416:15,102,632...15,106,372 		JBrowse link
G Ckap2 cytoskeleton associated protein 2 acts_upstream_of_or_within ISO (PMID:16061649) MGI PMID:16061649 NCBI chrNW_004955431:5,416,596...5,429,465
Ensembl chrNW_004955431:5,418,103...5,427,463 		JBrowse link
G Clasp1 cytoplasmic linker associated protein 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:15631994)
(PMID:11290329)
(PMID:16866869)		 UniProt
MGI		 PMID:11290329 PMID:15631994 PMID:16866869 NCBI chrNW_004955459:8,382,671...8,628,048
Ensembl chrNW_004955459:8,408,160...8,629,344 		JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 acts_upstream_of_or_within ISO (PMID:11290329)
(PMID:17113391)		 RGD
MGI		 PMID:11290329 PMID:17113391 RGD:68300 NCBI chrNW_004955421:767,648...957,160
Ensembl chrNW_004955421:767,210...897,457 		JBrowse link
G Diaph3 diaphanous related formin 3 acts_upstream_of_or_within ISO (PMID:18458159) MGI PMID:18458159 NCBI chrNW_004955404:44,653,308...45,106,943
Ensembl chrNW_004955404:44,653,501...45,105,966 		JBrowse link
G Eml4 EMAP like 4 acts_upstream_of_or_within ISO (PMID:17196341) MGI PMID:17196341 NCBI chrNW_004955441:9,633,906...9,715,866
Ensembl chrNW_004955441:9,640,899...9,713,596 		JBrowse link
G Fgf13 fibroblast growth factor 13 involved_in ISO (MGI:5431268|PMID:22726441) UniProt PMID:22726441 MGI:5431268 NCBI chrNW_004955489:6,122,707...6,621,624
Ensembl chrNW_004955489:6,123,633...6,621,692 		JBrowse link
G Gas2l1 growth arrest specific 2 like 1 involved_in ISO (PMID:12584248) UniProt PMID:12584248 NCBI chrNW_004955455:3,613,092...3,618,476
Ensembl chrNW_004955455:3,613,092...3,621,306 		JBrowse link
G Gas2l2 growth arrest specific 2 like 2 involved_in ISO (PMID:12584248) UniProt PMID:12584248 NCBI chrNW_004955481:10,190,738...10,202,298
Ensembl chrNW_004955481:10,193,077...10,200,959 		JBrowse link
G Hdac6 histone deacetylase 6 acts_upstream_of_or_within ISO (PMID:12486003) MGI PMID:12486003 NCBI chrNW_004955543:348,314...378,391
Ensembl chrNW_004955543:348,019...378,071 		JBrowse link
G Hdgfl3 HDGF like 3 involved_in ISO (MGI:3849122|PMID:19237540) UniProt PMID:19237540 MGI:3849122 NCBI chrNW_004955416:13,501,132...13,561,095
Ensembl chrNW_004955416:13,538,387...13,561,095 		JBrowse link
G Katnb1 katanin regulatory subunit B1 involved_in ISO (PMID:10751153) UniProt PMID:10751153 NCBI chrNW_004955433:15,345,246...15,365,986
Ensembl chrNW_004955433:15,345,246...15,366,039 		JBrowse link
G Map1a microtubule associated protein 1A ISO RGD PMID:11896150 RGD:71122 NCBI chrNW_004955416:10,052,964...10,073,318
Ensembl chrNW_004955416:10,053,010...10,071,421 		JBrowse link
G Map1b microtubule associated protein 1B ISO RGD PMID:11896150 RGD:71122 NCBI chrNW_004955575:914,607...1,020,971
Ensembl chrNW_004955575:913,723...1,021,028 		JBrowse link
G Map2 microtubule associated protein 2 involved_in ISO PMID:11029056 CAFA PMID:11029056 RGD:12793013 NCBI chrNW_004955457:5,678,826...5,816,114
Ensembl chrNW_004955457:5,678,436...5,875,024 		JBrowse link
G Mid1 midline 1 acts_upstream_of_or_within ISO (PMID:15070402) MGI PMID:15070402 NCBI chrNW_004955544:2,379,766...2,718,282
Ensembl chrNW_004955544:2,484,854...2,719,112 		JBrowse link
G Mid1ip1 MID1 interacting protein 1 acts_upstream_of_or_within ISO (PMID:15070402) MGI PMID:15070402 NCBI chrNW_004955566:287,578...289,803
Ensembl chrNW_004955566:287,578...289,803 		JBrowse link
G Nav3 neuron navigator 3 involved_in ISO (PMID:25678558) UniProt PMID:25678558 NCBI chrNW_004955405:16,428,643...17,213,253
Ensembl chrNW_004955405:16,869,441...17,213,325 		JBrowse link
G Specc1l sperm antigen with calponin homology and coiled-coil domains 1 like acts_upstream_of_or_within ISO (PMID:21703590) MGI PMID:21703590 NCBI chrNW_004955455:7,739,105...7,879,489
Ensembl chrNW_004955455:7,739,463...7,882,427 		JBrowse link
G Spef1 sperm flagellar 1 involved_in ISO (MGI:5908342|PMID:16206169) UniProt PMID:16206169 MGI:5908342 NCBI chrNW_004955415:14,620,593...14,626,049
Ensembl chrNW_004955415:14,620,593...14,626,049 		JBrowse link
G Stmn2 stathmin 2 involved_in ISO (PMID:18452648) UniProt PMID:18452648 NCBI chrNW_004955444:1,585,042...1,646,812 JBrowse link
G Taok1 TAO kinase 1 involved_in ISO (PMID:12639963) ARUK-UCL PMID:12639963 NCBI chrNW_004955481:3,698,686...3,836,209
Ensembl chrNW_004955481:3,705,202...3,772,116 		JBrowse link
G Tpx2 TPX2 microtubule nucleation factor involved_in ISO (PMID:26414402) CACAO PMID:26414402 NCBI chrNW_004955422:29,170,695...29,233,924
Ensembl chrNW_004955422:29,171,329...29,232,891 		JBrowse link
G Trim54 tripartite motif containing 54 acts_upstream_of_or_within ISO (PMID:10953002) MGI PMID:10953002 NCBI chrNW_004955469:9,258,946...9,277,275
Ensembl chrNW_004955469:9,258,946...9,277,275 		JBrowse link
G Ttbk2 tau tubulin kinase 2 involved_in ISO (PMID:26323690) ARUK-UCL PMID:26323690 NCBI chrNW_004955416:9,412,297...9,518,561
Ensembl chrNW_004955416:9,412,297...9,559,655 		JBrowse link
G Wdr47 WD repeat domain 47 acts_upstream_of_or_within ISO (PMID:29078390) MGI PMID:29078390 NCBI chrNW_004955435:12,414,964...12,479,883
Ensembl chrNW_004955435:12,414,600...12,466,040 		JBrowse link
positive regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arpc2 actin related protein 2/3 complex subunit 2 ISO RGD PMID:15252126 RGD:2306210 NCBI chrNW_004955453:15,117,978...15,145,895
Ensembl chrNW_004955453:15,116,093...15,146,041 		JBrowse link
G Cfl1 cofilin 1 ISO RGD PMID:23704350 RGD:11570555 NCBI chrNW_004955422:19,479,181...19,482,571
Ensembl chrNW_004955422:19,479,181...19,482,571 		JBrowse link
regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtpn myotrophin involved_in ISO (PMID:16895918) UniProt PMID:16895918 NCBI chrNW_004955494:6,805,518...6,844,454
Ensembl chrNW_004955494:6,805,262...6,845,394 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12321
    negative regulation of biological process 4690
      negative regulation of cellular process 4380
        negative regulation of cellular component organization 693
          negative regulation of protein-containing complex disassembly 65
            negative regulation of protein depolymerization 55
              negative regulation of actin filament depolymerization + 26
              negative regulation of intermediate filament depolymerization 0
              negative regulation of microtubule depolymerization + 30
              negative regulation of synaptic vesicle uncoating 0
Path 2
Term Annotations click to browse term
  biological_process 12321
    cellular process 11505
      cellular component organization or biogenesis 5341
        cellular component organization 5212
          cellular component disassembly 435
            protein-containing complex disassembly 212
              regulation of protein-containing complex disassembly 103
                regulation of protein depolymerization 68
                  negative regulation of protein depolymerization 55
                    negative regulation of actin filament depolymerization + 26
                    negative regulation of intermediate filament depolymerization 0
                    negative regulation of microtubule depolymerization + 30
                    negative regulation of synaptic vesicle uncoating 0
paths to the root