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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of signal transduction by p53 class mediator
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Accession:GO:1901798 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of signal transduction by p53 class mediator.
Synonyms:exact_synonym: up-regulation of signal transduction by p53 class mediator;   upregulation of signal transduction by p53 class mediator
 narrow_synonym: activation of signal transduction by p53 class mediator



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positive regulation of signal transduction by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:16173922)
UniProt
Ensembl
RGD
PMID:16173922 GO_REF:0000024 GO_REF:0000107 NCBI chr10:82,390,845...82,402,814
Ensembl chr10:81,894,393...81,903,590
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in ISO (PMID:16173922) RGD PMID:16173922 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Chd5 chromodomain helicase DNA binding protein 5 involved_in ISS
ISO
GO_REF:0000024
(PMID:17289567)
UniProt
RGD
PMID:17289567 GO_REF:0000024 NCBI chr 5:168,130,851...168,181,705
Ensembl chr 5:162,848,394...162,896,291
JBrowse link
G Dvl2 dishevelled segment polarity protein 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:17593335)
Ensembl
RGD
PMID:17593335 GO_REF:0000107 NCBI chr10:55,222,245...55,231,506
Ensembl chr10:54,723,411...54,732,820
JBrowse link
G Hexim1 HEXIM P-TEFb complex subunit 1 involved_in ISO (PMID:22948151) RGD PMID:22948151 NCBI chr10:88,562,889...88,565,001
Ensembl chr10:88,062,803...88,066,189
JBrowse link
G Pml PML nuclear body scaffold involved_in ISO
IEA
(PMID:10910364)
GO_REF:0000107
RGD
Ensembl
PMID:10910364 GO_REF:0000107 NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A involved_in ISO (PMID:14635196) RGD PMID:14635196 NCBI chr 1:105,136,521...105,139,596
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Rpl11 ribosomal protein L11 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:21804542)
UniProt
Ensembl
RGD
PMID:21804542 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:153,557,592...153,561,230
Ensembl chr 5:148,274,069...148,277,599
JBrowse link
G Rpl23 ribosomal protein L23 involved_in ISO (PMID:15314173) RGD PMID:15314173 NCBI chr10:83,268,223...83,272,184
Ensembl chr10:82,771,538...82,775,870
JBrowse link
G Rpl37 ribosomal protein L37 involved_in ISO (PMID:23874713) RGD PMID:23874713 NCBI chr 2:55,942,827...55,944,905
Ensembl chr 2:54,215,469...54,217,442
JBrowse link
G Rps15 ribosomal protein S15 involved_in ISO
IEA
(PMID:23874713)
GO_REF:0000107
RGD
Ensembl
PMID:23874713 GO_REF:0000107 NCBI chr 7:10,066,572...10,068,167
Ensembl chr 7:9,416,004...9,417,450
Ensembl chr 7:9,416,004...9,417,450
JBrowse link
G Rps20 ribosomal protein S20 involved_in ISO (PMID:23874713) RGD PMID:23874713 NCBI chr 5:21,616,687...21,618,068
Ensembl chr 5:16,819,304...16,820,475
Ensembl chr 9:16,819,304...16,820,475
Ensembl chr 3:16,819,304...16,820,475
Ensembl chr 5:16,819,304...16,820,475
JBrowse link
G Smarca4 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4 involved_in ISO (PMID:17938176) RGD PMID:17938176 NCBI chr 8:28,438,370...28,535,071
Ensembl chr 8:20,167,717...20,258,975
JBrowse link
positive regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd1 ankyrin repeat domain 1 involved_in ISO
IEA
(PMID:20599664)
GO_REF:0000107
RGD
Ensembl
PMID:20599664 GO_REF:0000107 NCBI chr 1:243,228,460...243,237,014
Ensembl chr 1:233,815,851...233,834,919
JBrowse link
G Atm ATM serine/threonine kinase involved_in ISO (PMID:9733515) RGD PMID:9733515 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atr ATR serine/threonine kinase involved_in IEA
ISO
GO_REF:0000107
(PMID:9733515), (PMID:9925639)
Ensembl
RGD
PMID:9733515 PMID:9925639 GO_REF:0000107 NCBI chr 8:105,306,299...105,403,742
Ensembl chr 8:96,426,724...96,524,136
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in ISO (PMID:9529249) RGD PMID:9529249 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Ddx5 DEAD-box helicase 5 involved_in ISO
IEA
(PMID:15660129)
GO_REF:0000107
RGD
Ensembl
PMID:15660129 GO_REF:0000107 NCBI chr10:92,224,393...92,231,928
Ensembl chr10:91,723,508...91,732,283
JBrowse link
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:3574590 (PMID:15680327)
GO_REF:0000002
RGD
InterPro
PMID:15680327 GO_REF:0000002 NCBI chr17:26,354,247...26,364,953
Ensembl chr17:26,148,633...26,215,720
JBrowse link
G Hic1 HIC ZBTB transcriptional repressor 1 involved_in ISO (PMID:16269335) RGD PMID:16269335 NCBI chr10:60,512,855...60,517,812
Ensembl chr10:60,011,528...60,019,475
JBrowse link
G Ing4 inhibitor of growth family, member 4 involved_in ISO
IEA
(PMID:15251430)
GO_REF:0000107
RGD
Ensembl
PMID:15251430 GO_REF:0000107 NCBI chr 4:159,528,183...159,536,762
Ensembl chr 4:157,841,951...157,850,265
JBrowse link
G Pla2r1 phospholipase A2 receptor 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:19197340)
UniProt
Ensembl
RGD
PMID:19197340 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:65,292,629...65,422,462
Ensembl chr 3:44,883,943...45,013,660
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:15102863)
(PMID:14500851)
RGD PMID:14500851 PMID:15102863 NCBI chr18:62,255,970...62,262,384
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Rpl26 ribosomal protein L26 involved_in ISO (PMID:16213212) RGD PMID:16213212 NCBI chr10:54,109,692...54,112,822
Ensembl chr10:53,610,421...53,613,966
JBrowse link
G Spred1 sprouty-related, EVH1 domain containing 1 involved_in ISO
IEA
(PMID:20736167)
GO_REF:0000107
RGD
Ensembl
PMID:20736167 GO_REF:0000107 NCBI chr 3:124,437,230...124,504,358
Ensembl chr 3:103,983,072...104,049,718
JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 involved_in ISO (PMID:20736167) RGD PMID:20736167 NCBI chr14:98,350,577...98,452,143
Ensembl chr14:94,148,837...94,249,162
JBrowse link
G Zfp385a zinc finger protein 385A involved_in ISO
IEA
(PMID:17719541)
GO_REF:0000107
RGD
Ensembl
PMID:17719541 GO_REF:0000107 NCBI chr 7:136,327,393...136,354,017
Ensembl chr 7:134,448,921...134,475,548
JBrowse link
G Znhit1 zinc finger, HIT-type containing 1 involved_in ISO
IEA
(PMID:17700068)
GO_REF:0000107
RGD
Ensembl
PMID:17700068 GO_REF:0000107 NCBI chr12:25,323,292...25,329,566
Ensembl chr12:19,686,148...19,692,880
JBrowse link
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif5a eukaryotic translation initiation factor 5A involved_in ISO (PMID:15371445) RGD PMID:15371445 NCBI chr10:55,138,821...55,143,272
Ensembl chr10:54,640,024...54,644,656
JBrowse link
G Mir186 microRNA 186 acts_upstream_of ISO (PMID:27714074) RGD PMID:27714074 NCBI chr 2:249,241,650...249,241,735
Ensembl chr 2:246,582,806...246,582,891
JBrowse link
G Msx1 msh homeobox 1 involved_in ISO (PMID:15705871) RGD PMID:15705871 NCBI chr14:77,185,802...77,189,735
Ensembl chr14:72,961,148...72,964,966
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO (PMID:10962037) RGD PMID:10962037 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Rps7 ribosomal protein S7 involved_in ISO (PMID:17310983) RGD PMID:17310983 NCBI chr 6:50,994,581...50,999,447
Ensembl chr 6:45,223,980...45,271,145
Ensembl chr 5:45,223,980...45,271,145
JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 involved_in ISO (PMID:24523556) RGD PMID:24523556 NCBI chr 2:236,411,194...236,445,225
Ensembl chr 2:233,750,838...233,784,784
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 involved_in ISO (PMID:17805299) RGD PMID:17805299 NCBI chr 3:128,620,320...128,724,716
Ensembl chr 3:108,169,980...108,269,822
JBrowse link
G Ubb ubiquitin B acts_upstream_of_or_within ISO
IEA
(PMID:17571083)
GO_REF:0000107
RGD
Ensembl
PMID:17571083 GO_REF:0000107 NCBI chr10:47,746,923...47,748,628
Ensembl chr10:47,245,637...47,249,333
JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Knl1 kinetochore scaffold 1 acts_upstream_of_or_within ISO (PMID:31197172) RGD PMID:31197172 NCBI chr 3:126,483,498...126,545,774
Ensembl chr 3:106,029,661...106,091,915
JBrowse link
G Rpl26 ribosomal protein L26 involved_in ISO (PMID:16213212) RGD PMID:16213212 NCBI chr10:54,109,692...54,112,822
Ensembl chr10:53,610,421...53,613,966
JBrowse link
G Steap3 STEAP3 metalloreductase acts_upstream_of_or_within ISO MGI:4398911 (PMID:18617898) RGD PMID:18617898 NCBI chr13:33,904,710...33,950,100
Ensembl chr13:31,351,954...31,396,519
JBrowse link
G Tp73 tumor protein p73 acts_upstream_of_or_within ISO
IEA
MGI:2442925|MGI:98834 (PMID:15983387)
GO_REF:0000107
RGD
Ensembl
PMID:15983387 GO_REF:0000107 NCBI chr 5:169,903,801...169,988,075
Ensembl chr 5:164,621,377...164,681,128
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      signal transduction 7301
        intracellular signal transduction 3189
          signal transduction by p53 class mediator 175
            positive regulation of signal transduction by p53 class mediator 38
              positive regulation of DNA damage response, signal transduction by p53 class mediator 15
              positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator + 12
Path 2
Term Annotations click to browse term
  biological_process 20558
    biological regulation 13833
      regulation of biological process 13394
        signaling 7862
          signal transduction 7301
            intracellular signal transduction 3189
              signal transduction by p53 class mediator 175
                regulation of signal transduction by p53 class mediator 105
                  positive regulation of signal transduction by p53 class mediator 38
                    positive regulation of DNA damage response, signal transduction by p53 class mediator 15
                    positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator + 12
paths to the root