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ONTOLOGY REPORT - ANNOTATIONS

Term:organic hydroxy compound biosynthetic process
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Accession:GO:1901617 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of organic hydroxy compound.
Synonyms:exact_synonym: organic hydroxy compound anabolism;   organic hydroxy compound biosynthesis;   organic hydroxy compound formation;   organic hydroxy compound synthesis


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organic hydroxy compound biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP39A1 cytochrome P450 family 39 subfamily A member 1 involved_in IEA UniProt GO_REF:0000117 NCBI chr 6:46,132,584...46,235,578
Ensembl chr 6:47,404,969...47,507,600 		JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 involved_in IEA UniProt GO_REF:0000117 NCBI chr 7:84,110,130...84,132,870
Ensembl chr 7:97,708,806...97,729,824 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase involved_in IEA UniProt GO_REF:0000117 NCBI chr11:66,450,230...66,464,214
Ensembl chr11:69,721,741...69,735,715 		JBrowse link
aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1H calcium voltage-gated channel subunit alpha1 H involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:1,195,364...1,222,917 JBrowse link
G CYP11B1 cytochrome P450 family 11 subfamily B member 1 involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:11832364 GO_REF:0000107 GO_REF:0000118 RGD:727991 NCBI chr 8:139,584,976...139,592,466
Ensembl chr 8:142,629,127...142,634,654 		JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:1686470), (PMID:8645611) Ensembl
MGI
TreeGrafter		 PMID:1686470 PMID:8645611 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:139,622,632...139,630,014
Ensembl chr 8:142,666,534...142,672,575 		JBrowse link
bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCD3 ATP binding cassette subfamily D member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:97,079,326...97,179,886
Ensembl chr 1:95,808,027...95,907,864 		JBrowse link
G ACOX2 acyl-CoA oxidase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:58,442,532...58,474,601
Ensembl chr 3:59,852,771...59,884,548 		JBrowse link
G AKR1D1 aldo-keto reductase family 1 member D1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:7508385) MGI
InterPro
Ensembl		 PMID:7508385 GO_REF:0000002 GO_REF:0000107 NCBI chr 7:130,023,017...130,076,397
Ensembl chr 7:142,525,467...142,571,331 		JBrowse link
G AMACR alpha-methylacyl-CoA racemase ISO RGD PMID:11964182 RGD:704372 NCBI chr 5:76,336,631...76,358,724
Ensembl chr 5:81,687,891...81,742,003 		JBrowse link
G BAAT bile acid-CoA:amino acid N-acyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:72,568,002...72,593,179
Ensembl chr 9:100,563,040...100,586,189 		JBrowse link
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:106,042,235...106,076,840
Ensembl chr2B:224,637,238...224,671,474 		JBrowse link
G CYP39A1 cytochrome P450 family 39 subfamily A member 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:46,132,584...46,235,578
Ensembl chr 6:47,404,969...47,507,600 		JBrowse link
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:84,110,130...84,132,870
Ensembl chr 7:97,708,806...97,729,824 		JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in IEA Ensembl
TreeGrafter
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:54,942,509...54,952,500
Ensembl chr 8:56,593,799...56,604,037 		JBrowse link
G CYP7B1 cytochrome P450 family 7 subfamily B member 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:61,135,307...61,335,838
Ensembl chr 8:62,806,637...63,006,386 		JBrowse link
G CYP8B1 cytochrome P450 family 8 subfamily B member 1 involved_in ISO (PMID:14643796)
(MGI:3588413|PMID:12393855)		 UniProt PMID:12393855 PMID:14643796 MGI:3588413 NCBI chr 3:42,775,679...42,779,440
Ensembl chr 3:43,824,423...43,842,716 		JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22912762) Ensembl
MGI		 PMID:22912762 GO_REF:0000107 NCBI chr 1:6,771,619...6,786,217
Ensembl chr 1:8,011,848...8,033,674 		JBrowse link
G HNF1A HNF1 homeobox A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11279518) Ensembl
MGI		 PMID:11279518 GO_REF:0000107 NCBI chr12:118,562,308...118,584,596
Ensembl chr12:121,932,671...121,955,911 		JBrowse link
G HSD17B10 hydroxysteroid 17-beta dehydrogenase 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:45,645,849...45,649,039
Ensembl chr  X:53,754,164...53,757,643 		JBrowse link
G PEX2 peroxisomal biogenesis factor 2 acts_upstream_of_or_within ISO (PMID:14673138) MGI PMID:14673138 NCBI chr 8:73,508,349...73,526,560
Ensembl chr 8:75,146,255...75,147,172 		JBrowse link
G SLC27A2 solute carrier family 27 member 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr15:29,130,262...29,182,752
Ensembl chr15:47,452,227...47,505,066 		JBrowse link
G SLC27A5 solute carrier family 27 member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:55,507,455...55,520,448
Ensembl chr19:64,329,567...64,342,630 		JBrowse link
G STAR steroidogenic acute regulatory protein ISO RGD PMID:15382124 RGD:1600081 NCBI chr 8:37,446,334...37,454,102
Ensembl chr 8:34,623,201...34,629,544 		JBrowse link
brassinosteroid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHCR7 7-dehydrocholesterol reductase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:66,450,230...66,464,214
Ensembl chr11:69,721,741...69,735,715 		JBrowse link
G SRD5A2 steroid 5 alpha-reductase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2A:31,542,646...31,597,394
Ensembl chr2A:31,610,487...31,665,718 		JBrowse link
calcitriol biosynthetic process from calciol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 involved_in IEA Ensembl
UniProt		 GO_REF:0000107 GO_REF:0000117 NCBI chr2B:106,042,235...106,076,840
Ensembl chr2B:224,637,238...224,671,474 		JBrowse link
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 involved_in IEA Ensembl
UniProt		 GO_REF:0000107 GO_REF:0000117 NCBI chr12:31,158,814...31,164,462
Ensembl chr12:31,419,773...31,424,822 		JBrowse link
G CYP2R1 cytochrome P450 family 2 subfamily R member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:14,960,651...14,989,083
Ensembl chr11:14,656,939...14,671,584 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 involved_in IEA GOC GO_REF:0000108 NCBI chr 7:91,797,037...91,824,696
Ensembl chr 7:105,230,666...105,258,401 		JBrowse link
catecholamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRHR2 corticotropin releasing hormone receptor 2 ISO RGD PMID:17194738 RGD:5131263 NCBI chr 7:31,265,619...31,313,902
Ensembl chr 7:31,386,026...31,434,220 		JBrowse link
G DDC dopa decarboxylase involved_in IEA UniProt GO_REF:0000043 NCBI chr 7:51,101,169...51,206,031
Ensembl chr 7:51,345,228...51,449,710 		JBrowse link
G HDC histidine decarboxylase involved_in IEA UniProt GO_REF:0000043 NCBI chr15:29,188,296...29,212,327
Ensembl chr15:47,510,629...47,534,577 		JBrowse link
G PNMT phenylethanolamine N-methyltransferase involved_in IEA UniProt GO_REF:0000043 NCBI chr17:17,618,399...17,620,691
Ensembl chr17:17,835,277...17,837,180 		JBrowse link
G TH tyrosine hydroxylase involved_in ISO
IEA		 RGD
InterPro
UniProt		 PMID:20025246 GO_REF:0000002 GO_REF:0000043 RGD:4139888 NCBI chr11:2,204,820...2,212,750
Ensembl chr11:2,231,248...2,242,433 		JBrowse link
cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 acts_upstream_of_or_within ISO (PMID:8647961) MGI PMID:8647961 NCBI chr11:111,673,539...111,675,428
Ensembl chr11:115,606,136...115,608,122 		JBrowse link
G CFTR CF transmembrane conductance regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17085523) Ensembl
MGI		 PMID:17085523 GO_REF:0000107 NCBI chr 7:109,449,847...109,633,023
Ensembl chr 7:122,129,798...122,327,864 		JBrowse link
G DHCR24 24-dehydrocholesterol reductase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:11519011)
(PMID:14684813), (PMID:16321981), (PMID:16513830)		 MGI
Ensembl		 PMID:11519011 PMID:14684813 PMID:16321981 PMID:16513830 GO_REF:0000107 NCBI chr 1:54,126,170...54,163,713
Ensembl chr 1:55,714,693...55,754,698 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase involved_in ISO
IEA		 RGD
TreeGrafter
UniProt
Ensembl		 PMID:9831636 PMID:10329655 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 RGD:2316918 RGD:632010 NCBI chr11:66,450,230...66,464,214
Ensembl chr11:69,721,741...69,735,715 		JBrowse link
G EBP EBP cholestenol delta-isomerase involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:11171067 GO_REF:0000118 RGD:628445 NCBI chr  X:40,820,042...40,826,957 JBrowse link
G FDFT1 farnesyl-diphosphate farnesyltransferase 1 involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:16440058 GO_REF:0000118 RGD:1626611 NCBI chr 8:7,363,250...7,399,863 JBrowse link
G G6PD glucose-6-phosphate dehydrogenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:143,972,798...143,988,960
Ensembl chr  X:153,843,092...153,860,674 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15845870), (PMID:7798939), (PMID:8647961) Ensembl
MGI
UniProt		 PMID:7798939 PMID:8647961 PMID:15845870 GO_REF:0000043 GO_REF:0000107 NCBI chr 5:39,936,630...39,961,519
Ensembl chr 5:40,548,919...40,573,785 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 5:67,067,001...67,091,786
Ensembl chr 5:72,116,228...72,141,050 		JBrowse link
G HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:82,778,489...82,798,987
Ensembl chr 1:117,775,770...117,796,679 		JBrowse link
G HSD17B7 hydroxysteroid 17-beta dehydrogenase 7 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:138,204,544...138,226,689 JBrowse link
G IDI1 isopentenyl-diphosphate delta isomerase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr10:1,078,107...1,087,054
Ensembl chr10:1,124,920...1,133,234 		JBrowse link
G IDI2 isopentenyl-diphosphate delta isomerase 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr10:1,056,280...1,062,070
Ensembl chr10:1,102,655...1,108,246 		JBrowse link
G INSIG1 insulin induced gene 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16955138) Ensembl
MGI
TreeGrafter		 PMID:16955138 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:146,893,730...146,906,329
Ensembl chr 7:158,619,531...158,632,012 		JBrowse link
G INSIG2 insulin induced gene 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16955138) Ensembl
MGI
TreeGrafter		 PMID:16955138 GO_REF:0000107 GO_REF:0000118 NCBI chr2B:5,046,971...5,068,757
Ensembl chr2B:118,632,402...118,652,647 		JBrowse link
G LBR lamin B receptor involved_in IEA UniProt
TreeGrafter
Ensembl		 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:200,865,602...200,892,199
Ensembl chr 1:205,870,394...205,893,032 		JBrowse link
G LIPA lipase A, lysosomal acid type involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25147230), (PMID:29599133) Ensembl
MGI		 PMID:25147230 PMID:29599133 GO_REF:0000107 NCBI chr10:85,938,240...85,976,610
Ensembl chr10:89,477,082...89,516,874 		JBrowse link
G LOC100982559 NADH-cytochrome b5 reductase 3 involved_in IEA UniProt GO_REF:0000043 NCBI chr22:23,513,724...23,544,746
Ensembl chr22:41,666,548...41,694,104 		JBrowse link
G LOC100985156 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12829805) Ensembl
MGI
TreeGrafter		 PMID:12829805 GO_REF:0000107 GO_REF:0000118 NCBI chr10:38,424,713...38,447,193
Ensembl chr 1:142,001,162...142,022,865 		JBrowse link
G LSS lanosterol synthase involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:1429550 PMID:16440058 GO_REF:0000107 GO_REF:0000118 RGD:1626611 RGD:2316919 NCBI chr21:32,535,564...32,571,379
Ensembl chr21:45,787,252...45,822,181 		JBrowse link
G MVD mevalonate diphosphate decarboxylase involved_in IEA UniProt GO_REF:0000041 GO_REF:0000043 NCBI chr16:69,365,070...69,376,149
Ensembl chr16:89,025,572...89,036,964 		JBrowse link
G MVK mevalonate kinase involved_in IEA UniProt
TreeGrafter
Ensembl		 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr12:107,150,477...107,173,978
Ensembl chr12:110,544,991...110,568,524 		JBrowse link
G NPC1L1 NPC1 like intracellular cholesterol transporter 1 involved_in ISO (PMID:17140581) HGNC-UCL PMID:17140581 NCBI chr 7:45,227,289...45,256,094
Ensembl chr 7:45,297,271...45,324,692 		JBrowse link
G PMVK phosphomevalonate kinase involved_in IEA UniProt
TreeGrafter
Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:130,273,246...130,286,614
Ensembl chr 1:133,882,840...133,894,818 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 5:69,581,748...69,620,721
Ensembl chr 5:74,627,830...74,666,505 		JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:55,928,577...55,998,628
Ensembl chr 1:57,664,237...57,702,227 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:9329978) Ensembl
MGI		 PMID:9329978 GO_REF:0000107 NCBI chr17:33,458,196...33,484,643
Ensembl chr17:38,405,794...38,432,045 		JBrowse link
G TM7SF2 transmembrane 7 superfamily member 2 involved_in IEA UniProt
TreeGrafter
Ensembl		 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr11:60,473,934...60,478,579
Ensembl chr11:63,812,769...63,816,812 		JBrowse link
cholesterol biosynthetic process via 24,25-dihydrolanosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 ISO RGD PMID:7581240 RGD:2316902 NCBI chr 7:84,110,130...84,132,870
Ensembl chr 7:97,708,806...97,729,824 		JBrowse link
cholesterol biosynthetic process via desmosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHCR24 24-dehydrocholesterol reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:54,126,170...54,163,713
Ensembl chr 1:55,714,693...55,754,698 		JBrowse link
cholesterol biosynthetic process via lathosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MSMO1 methylsterol monooxygenase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:157,523,099...157,538,508
Ensembl chr 4:169,606,809...169,622,212 		JBrowse link
G SC5D sterol-C5-desaturase involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:7961720 GO_REF:0000118 RGD:2316911 NCBI chr11:116,139,979...116,160,745
Ensembl chr11:120,063,743...120,078,386 		JBrowse link
cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1H calcium voltage-gated channel subunit alpha1 H involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:1,195,364...1,222,917 JBrowse link
G CYP11B1 cytochrome P450 family 11 subfamily B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:139,584,976...139,592,466
Ensembl chr 8:142,629,127...142,634,654 		JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 involved_in
NOT|involved_in		 IEA
ISO		 (PMID:9703385) Ensembl
BHF-UCL		 PMID:9703385 GO_REF:0000107 NCBI chr 8:139,622,632...139,630,014
Ensembl chr 8:142,666,534...142,672,575 		JBrowse link
diol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPHX1 epoxide hydrolase 1 ISO RGD PMID:2507189 RGD:11252156 NCBI chr 1:201,271,366...201,306,635
Ensembl chr 1:206,272,866...206,307,581 		JBrowse link
dolichol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHDDS dehydrodolichyl diphosphate synthase subunit involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:25,696,229...25,735,319
Ensembl chr 1:26,760,535...26,799,049 		JBrowse link
G LOC129394211 dehydrodolichyl diphosphate synthase complex subunit NUS1-like involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr16:24,960,843...24,963,458 JBrowse link
G NUS1 NUS1 dehydrodolichyl diphosphate synthase subunit acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25066056) MGI
TreeGrafter
InterPro		 PMID:25066056 GO_REF:0000002 GO_REF:0000118 NCBI chr 6:115,486,422...115,521,317 JBrowse link
G SRD5A3 steroid 5 alpha-reductase 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:68,565,400...68,591,400
Ensembl chr 4:75,131,196...75,155,347 		JBrowse link
dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGTR1 angiotensin II receptor type 1 ISO RGD PMID:20097214 RGD:6903884 NCBI chr 3:145,722,475...145,767,550
Ensembl chr 3:153,341,947...153,345,380 		JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO RGD PMID:20097214 RGD:6903884 NCBI chr  X:105,252,903...105,257,171
Ensembl chr  X:115,671,594...115,672,685 		JBrowse link
G DAO D-amino acid oxidase involved_in ISO (PMID:17303072)
(MGI:7574172|PMID:17042912)		 UniProt PMID:17042912 PMID:17303072 MGI:7574172 NCBI chr12:106,453,807...106,475,409
Ensembl chr12:109,849,995...109,870,065 		JBrowse link
G DDC dopa decarboxylase ISO RGD PMID:12703659 RGD:4139893 NCBI chr 7:51,101,169...51,206,031
Ensembl chr 7:51,345,228...51,449,710 		JBrowse link
G GCH1 GTP cyclohydrolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:35,428,676...35,489,359
Ensembl chr14:53,706,723...53,767,393 		JBrowse link
G GPR37 G protein-coupled receptor 37 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15218106) Ensembl
MGI		 PMID:15218106 GO_REF:0000107 NCBI chr 7:116,727,912...116,751,647
Ensembl chr 7:129,410,458...129,430,292 		JBrowse link
G LOC100977072 neuronal acetylcholine receptor subunit alpha-7 ISO RGD PMID:12438507 RGD:704388 NCBI chr15:10,525,535...10,667,227
Ensembl chr15:29,565,885...29,705,194 		JBrowse link
G LOC100988273 cytochrome P450 2D6-like ISO RGD PMID:19818757 RGD:5143981 NCBI chr22:23,022,449...23,031,627 JBrowse link
G NR4A2 nuclear receptor subfamily 4 group A member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16782508), (PMID:9608532) Ensembl
MGI		 PMID:9608532 PMID:16782508 GO_REF:0000107 NCBI chr2B:43,584,835...43,593,118
Ensembl chr2B:160,826,091...160,837,162 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9520487) Ensembl
MGI		 PMID:9520487 GO_REF:0000107 Ensembl chr 5:1,437,567...1,488,829 JBrowse link
G SNCA synuclein alpha acts_upstream_of_or_within ISO (PMID:10707987) MGI PMID:10707987 NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600 		JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in ISO (MGI:3622848|PMID:16257223) UniProt PMID:16257223 MGI:3622848 NCBI chr 1:193,907,398...194,005,800
Ensembl chr 1:198,758,751...198,859,041 		JBrowse link
G TH tyrosine hydroxylase involved_in IEA Ensembl
UniProt		 GO_REF:0000041 GO_REF:0000107 NCBI chr11:2,204,820...2,212,750
Ensembl chr11:2,231,248...2,242,433 		JBrowse link
dopamine biosynthetic process from tyrosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TH tyrosine hydroxylase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:9520487)
(PMID:7592982), (PMID:7715703)		 RGD
MGI
TreeGrafter
Ensembl		 PMID:2427363 PMID:7592982 PMID:7715703 PMID:9520487 PMID:19584816 GO_REF:0000107 GO_REF:0000118 RGD:1580046 RGD:5130972 NCBI chr11:2,204,820...2,212,750
Ensembl chr11:2,231,248...2,242,433 		JBrowse link
epinephrine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PNMT phenylethanolamine N-methyltransferase ISO RGD PMID:7914070 RGD:4139902 NCBI chr17:17,618,399...17,620,691
Ensembl chr17:17,835,277...17,837,180 		JBrowse link
G TH tyrosine hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:2,204,820...2,212,750
Ensembl chr11:2,231,248...2,242,433 		JBrowse link
ergosterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT2 acetyl-CoA acetyltransferase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:157,644,894...157,661,965
Ensembl chr 6:162,656,497...162,673,606 		JBrowse link
G FDFT1 farnesyl-diphosphate farnesyltransferase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:7,363,250...7,399,863 JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:39,936,630...39,961,519
Ensembl chr 5:40,548,919...40,573,785 		JBrowse link
G LBR lamin B receptor involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:200,865,602...200,892,199
Ensembl chr 1:205,870,394...205,893,032 		JBrowse link
G LOC100977118 NADH-cytochrome b5 reductase-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:53,442,480...53,476,136
Ensembl chr 1:55,042,138...55,065,899 		JBrowse link
G LSS lanosterol synthase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr21:32,535,564...32,571,379
Ensembl chr21:45,787,252...45,822,181 		JBrowse link
G MSMO1 methylsterol monooxygenase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:157,523,099...157,538,508
Ensembl chr 4:169,606,809...169,622,212 		JBrowse link
G MVK mevalonate kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:107,150,477...107,173,978
Ensembl chr12:110,544,991...110,568,524 		JBrowse link
G SC5D sterol-C5-desaturase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:116,139,979...116,160,745
Ensembl chr11:120,063,743...120,078,386 		JBrowse link
G SQLE squalene epoxidase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:121,684,269...121,708,131
Ensembl chr 8:124,435,668...124,459,441 		JBrowse link
flavonol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TGDS TDP-glucose 4,6-dehydratase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:75,747,686...75,770,010
Ensembl chr13:94,903,511...94,925,637 		JBrowse link
glycerol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GOT1 glutamic-oxaloacetic transaminase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17545671) Ensembl
MGI		 PMID:17545671 GO_REF:0000107 NCBI chr10:96,012,345...96,046,266
Ensembl chr10:99,506,205...99,540,178 		JBrowse link
G LEP leptin ISO RGD PMID:21068181 RGD:5128556 NCBI chr 7:120,230,896...120,248,602
Ensembl chr 7:132,885,011...132,901,519 		JBrowse link
G PGP phosphoglycolate phosphatase involved_in ISO (PMID:26755581)
(MGI:5707518|PMID:26755581)		 UniProt PMID:26755581 MGI:5707518 RGD:10679995 NCBI chr16:1,070,291...1,073,123 JBrowse link
glycerol biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PCK1 phosphoenolpyruvate carboxykinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11792850) Ensembl
MGI
TreeGrafter		 PMID:11792850 GO_REF:0000107 GO_REF:0000118 NCBI chr20:53,901,738...53,907,090
Ensembl chr20:55,179,429...55,184,920 		JBrowse link
G PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:4,872,276...4,882,118
Ensembl chr14:22,996,813...23,006,775 		JBrowse link
glycolate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARK7 Parkinsonism associated deglycase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:6,722,260...6,745,915
Ensembl chr 1:7,969,280...7,993,271 		JBrowse link
inositol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IMPA1 inositol monophosphatase 1 involved_in IEA UniProt GO_REF:0000041 NCBI chr 8:78,177,200...78,209,901
Ensembl chr 8:79,800,257...79,829,935 		JBrowse link
G IMPA2 inositol monophosphatase 2 involved_in IEA UniProt GO_REF:0000041 NCBI chr18:2,293,788...2,344,422
Ensembl chr18:4,557,280...4,608,991 		JBrowse link
G ISYNA1 inositol-3-phosphate synthase 1 involved_in IEA InterPro
TreeGrafter
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr19:17,913,400...17,916,789
Ensembl chr19:18,884,412...18,887,931 		JBrowse link
inositol phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IP6K1 inositol hexakisphosphate kinase 1 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 3:49,656,438...49,718,423
Ensembl chr 3:50,892,279...50,954,149 		JBrowse link
G IP6K2 inositol hexakisphosphate kinase 2 involved_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:48,608,902...48,638,185
Ensembl chr 3:49,690,486...49,719,798 		JBrowse link
G IP6K3 inositol hexakisphosphate kinase 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:11502751) MGI
TreeGrafter
Ensembl
InterPro		 PMID:11502751 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:33,294,835...33,320,117
Ensembl chr 6:34,403,261...34,428,386 		JBrowse link
G IPMK inositol polyphosphate multikinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15939867) InterPro
MGI
TreeGrafter		 PMID:15939867 GO_REF:0000002 GO_REF:0000118 NCBI chr10:54,718,987...54,799,264
Ensembl chr10:56,939,012...57,019,101 		JBrowse link
G IPPK inositol-pentakisphosphate 2-kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:63,737,324...63,793,348
Ensembl chr 9:91,808,757...91,864,773 		JBrowse link
G ITPKA inositol-trisphosphate 3-kinase A involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr15:20,434,532...20,444,389
Ensembl chr15:38,675,600...38,684,779 		JBrowse link
G ITPKB inositol-trisphosphate 3-kinase B involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 1:202,091,263...202,198,880
Ensembl chr 1:207,084,883...207,191,678 		JBrowse link
G ITPKC inositol-trisphosphate 3-kinase C involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr19:37,761,221...37,785,118
Ensembl chr19:46,267,754...46,290,935 		JBrowse link
G PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:98,475,410...98,558,189
Ensembl chr 5:104,175,883...104,258,688 		JBrowse link
inositol trisphosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLCG1 phospholipase C gamma 1 ISO RGD PMID:16973916 RGD:2299886 NCBI chr20:37,477,077...37,515,854
Ensembl chr20:38,572,709...38,615,145 		JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9013981) Ensembl
MGI		 PMID:9013981 GO_REF:0000107 NCBI chr16:62,383,270...62,561,579
Ensembl chr16:81,812,565...81,984,064 		JBrowse link
G POU1F1 POU class 1 homeobox 1 acts_upstream_of ISO (PMID:11371619) MGI PMID:11371619 NCBI chr 3:87,390,157...87,407,611
Ensembl chr 3:89,501,298...89,521,168 		JBrowse link
G PTAFR platelet activating factor receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9013981) Ensembl
MGI		 PMID:9013981 GO_REF:0000107 NCBI chr 1:27,405,880...27,436,184
Ensembl chr 1:28,447,833...28,448,861 		JBrowse link
G SCP2 sterol carrier protein 2 involved_in ISO (PMID:12641450) UniProt PMID:12641450 NCBI chr 1:52,195,491...52,324,227
Ensembl chr 1:53,797,254...53,924,939 		JBrowse link
lactate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INS insulin involved_in ISO (PMID:8069456) AgBase PMID:8069456 NCBI chr11:2,200,785...2,202,579
Ensembl chr11:2,218,117...2,231,666 		JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:6,722,260...6,745,915
Ensembl chr 1:7,969,280...7,993,271 		JBrowse link
G PER2 period circadian regulator 2 involved_in ISO (MGI:5546525|PMID:23977055) UniProt PMID:23977055 MGI:5546525 NCBI chr2B:125,477,021...125,521,577
Ensembl chr2B:244,328,122...244,371,040 		JBrowse link
lactate biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HTT huntingtin acts_upstream_of_or_within ISO (PMID:17708681) MGI PMID:17708681 NCBI chr 4:3,215,081...3,388,587
Ensembl chr 4:3,128,718...3,283,730 		JBrowse link
G LDHC lactate dehydrogenase C involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18367675) Ensembl
MGI		 PMID:18367675 GO_REF:0000107 NCBI chr11:18,450,117...18,489,321
Ensembl chr11:18,132,829...18,172,055 		JBrowse link
lipoxin A4 biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:7,026,839...7,041,598
Ensembl chr17:7,014,591...7,029,602 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase involved_in ISO (MGI:3579746|PMID:15708862) UniProt PMID:15708862 MGI:3579746 NCBI chr17:4,686,339...4,696,877
Ensembl chr17:4,677,125...4,687,669 		JBrowse link
G LOC100971127 arachidonate 15-lipoxygenase type B involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:43,609,146...43,619,713
Ensembl chr17:48,340,777...48,350,808 		JBrowse link
lipoxin B4 biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:7,026,839...7,041,598
Ensembl chr17:7,014,591...7,029,602 		JBrowse link
melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASIP agouti signaling protein involved_in
acts_upstream_of_or_within		 ISS
ISO		 (PMID:7665913) UniProt
MGI		 PMID:7665913 GO_REF:0000024 NCBI chr20:30,583,038...30,592,726
Ensembl chr20:31,718,169...31,727,217 		JBrowse link
G CITED1 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:61,537,949...61,543,545
Ensembl chr  X:71,621,785...71,625,702 		JBrowse link
G DCT dopachrome tautomerase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7665913) Ensembl
MGI
UniProt		 PMID:7665913 GO_REF:0000043 GO_REF:0000107 NCBI chr13:75,590,366...75,730,956
Ensembl chr13:94,773,794...94,816,083 		JBrowse link
G LOC100995427 D-dopachrome tautomerase involved_in IEA UniProt GO_REF:0000043 NCBI chr22:4,722,289...4,725,651
Ensembl chr22:22,805,705...22,811,057 		JBrowse link
G MC1R melanocortin 1 receptor acts_upstream_of_or_within ISO (PMID:7665913) MGI PMID:7665913 NCBI chr16:70,676,447...70,697,636 JBrowse link
G MYO5A myosin VA acts_upstream_of_or_within ISO (PMID:7665913) MGI PMID:7665913 NCBI chr15:31,246,192...31,470,040
Ensembl chr15:49,578,491...49,704,319 		JBrowse link
G OCA2 OCA2 melanosomal transmembrane protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7665913), (PMID:9548375) Ensembl
MGI
TreeGrafter		 PMID:7665913 PMID:9548375 GO_REF:0000107 GO_REF:0000118 NCBI chr15:1,811,728...2,192,018
Ensembl chr15:25,181,386...25,523,774 		JBrowse link
G PMEL premelanosome protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7665913) Ensembl
MGI		 PMID:7665913 GO_REF:0000107 NCBI chr12:32,946,951...32,958,205
Ensembl chr12:33,196,040...33,207,610 		JBrowse link
G SLC24A5 solute carrier family 24 member 5 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18166528) Ensembl
MGI		 PMID:18166528 GO_REF:0000107 NCBI chr15:27,069,937...27,091,619
Ensembl chr15:45,394,090...45,415,823 		JBrowse link
G TRPC1 transient receptor potential cation channel subfamily C member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:139,757,408...139,841,006
Ensembl chr 3:147,349,056...147,432,332 		JBrowse link
G TYR tyrosinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9548375)
(PMID:7665913)		 UniProt
MGI
TreeGrafter
Ensembl		 PMID:7665913 PMID:9548375 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr11:84,188,557...84,306,686
Ensembl chr11:87,769,606...87,888,138 		JBrowse link
G TYRP1 tyrosinase related protein 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 9:12,502,610...12,550,203
Ensembl chr 9:12,950,831...12,996,799 		JBrowse link
melanin biosynthetic process from tyrosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DCT dopachrome tautomerase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr13:75,590,366...75,730,956
Ensembl chr13:94,773,794...94,816,083 		JBrowse link
G OCA2 OCA2 melanosomal transmembrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:1,811,728...2,192,018
Ensembl chr15:25,181,386...25,523,774 		JBrowse link
G SLC45A2 solute carrier family 45 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:76,357,549...76,398,571
Ensembl chr 5:81,743,254...81,784,565 		JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:55,302,721...55,425,248
Ensembl chr 6:56,936,850...57,059,519 		JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:12,131,306...12,177,906
Ensembl chr11:11,824,955...11,871,139 		JBrowse link
G REST RE1 silencing transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:66,984,466...67,012,301
Ensembl chr 4:73,526,085...73,582,242 		JBrowse link
negative regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF19 fibroblast growth factor 19 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23747249) Ensembl
MGI		 PMID:23747249 GO_REF:0000107 NCBI chr11:64,794,157...64,800,512
Ensembl chr11:68,085,306...68,090,028 		JBrowse link
G MALRD1 MAM and LDL receptor class A domain containing 1 acts_upstream_of_or_within ISO (PMID:23747249) MGI PMID:23747249 NCBI chr10:19,461,865...19,886,155 JBrowse link
G PROX1 prospero homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:189,556,124...189,609,297
Ensembl chr 1:194,412,980...194,460,763 		JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in ISO
IEA		 RGD
Ensembl		 PMID:9225228 GO_REF:0000107 RGD:10059686 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490 		JBrowse link
G ERLIN1 ER lipid raft associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:96,756,261...96,791,925
Ensembl chr10:100,238,320...100,273,942 		JBrowse link
G ERLIN2 ER lipid raft associated 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:37,034,391...37,057,164
Ensembl chr 8:34,212,704...34,233,583 		JBrowse link
G IDI2 isopentenyl-diphosphate delta isomerase 2 acts_upstream_of_or_within ISO (PMID:17202134) MGI PMID:17202134 NCBI chr10:1,056,280...1,062,070
Ensembl chr10:1,102,655...1,108,246 		JBrowse link
G SOD1 superoxide dismutase 1 involved_in ISO (PMID:15473258) UniProt PMID:15473258 NCBI chr21:18,029,831...18,037,526 JBrowse link
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:55,302,721...55,425,248
Ensembl chr 6:56,936,850...57,059,519 		JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:12,131,306...12,177,906
Ensembl chr11:11,824,955...11,871,139 		JBrowse link
G REST RE1 silencing transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:66,984,466...67,012,301
Ensembl chr 4:73,526,085...73,582,242 		JBrowse link
negative regulation of inositol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ISYNA1 inositol-3-phosphate synthase 1 involved_in ISO PMID:19188364 UniProt PMID:19188364 RGD:153298950 NCBI chr19:17,913,400...17,916,789
Ensembl chr19:18,884,412...18,887,931 		JBrowse link
negative regulation of inositol phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLEK pleckstrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:68,414,281...68,446,647
Ensembl chr2A:69,537,983...69,570,393 		JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 ISO RGD PMID:7535379 RGD:7777104 NCBI chr10:47,642,312...48,935,188
Ensembl chr10:49,779,211...51,064,882 		JBrowse link
negative regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MFSD12 major facilitator superfamily domain containing 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:2,570,068...2,583,505
Ensembl chr19:3,520,399...3,532,767 		JBrowse link
G OPN3 opsin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:217,155,765...217,202,577
Ensembl chr 1:222,136,422...222,184,598 		JBrowse link
G RAPGEF2 Rap guanine nucleotide exchange factor 2 involved_in ISO (MGI:5499726|PMID:16272156) UniProt PMID:16272156 MGI:5499726 NCBI chr 4:151,419,402...151,680,769
Ensembl chr 4:163,316,396...163,487,495 		JBrowse link
G SLC24A5 solute carrier family 24 member 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18166528) Ensembl
MGI		 PMID:18166528 GO_REF:0000107 NCBI chr15:27,069,937...27,091,619
Ensembl chr15:45,394,090...45,415,823 		JBrowse link
G WNT5A Wnt family member 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:55,396,279...55,418,579
Ensembl chr 3:56,621,380...56,638,051 		JBrowse link
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKKL1 dickkopf like acrosomal protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:46,375,301...46,389,822
Ensembl chr19:55,301,955...55,313,690 		JBrowse link
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:21,310,228...21,335,985
Ensembl chr 1:22,255,056...22,268,801 		JBrowse link
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SNAI1 snail family transcriptional repressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:46,321,075...46,328,865
Ensembl chr20:47,384,818...47,390,733 		JBrowse link
G SNAI2 snail family transcriptional repressor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:45,341,857...45,345,544
Ensembl chr 8:42,723,971...42,730,904 		JBrowse link
norepinephrine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha acts_upstream_of_or_within ISO (PMID:4405722)
(PMID:4858102)		 MGI PMID:4405722 PMID:4858102 NCBI chr  X:67,093,675...67,231,318
Ensembl chr  X:77,255,312...77,342,756 		JBrowse link
G DBH dopamine beta-hydroxylase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:10051631), (PMID:9603211) RGD
MGI
TreeGrafter
Ensembl
UniProt		 PMID:9603211 PMID:10051631 PMID:10573542 GO_REF:0000041 GO_REF:0000107 GO_REF:0000118 RGD:1625403 NCBI chr 9:104,761,504...104,784,445
Ensembl chr 9:133,371,821...133,393,697 		JBrowse link
G EPAS1 endothelial PAS domain protein 1 ISO RGD PMID:19457096 RGD:5128877 NCBI chr2A:46,403,411...46,492,734
Ensembl chr2A:47,332,308...47,421,560 		JBrowse link
G GATA3 GATA binding protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10835639) Ensembl
MGI		 PMID:10835639 GO_REF:0000107 NCBI chr10:8,075,951...8,105,573
Ensembl chr10:8,064,207...8,086,272 		JBrowse link
G HAND2 heart and neural crest derivatives expressed 2 acts_upstream_of_positive_effect ISO (MGI:4413411|PMID:19008477) BHF-UCL PMID:19008477 MGI:4413411 NCBI chr 4:165,755,000...165,758,735 JBrowse link
G INSM1 INSM transcriptional repressor 1 involved_in ISO (MGI:3772428|PMID:18094025) UniProt PMID:18094025 MGI:3772428 NCBI chr20:20,317,060...20,320,051 JBrowse link
G KL klotho ISO RGD PMID:20086041 RGD:10403068 NCBI chr13:14,272,463...14,321,122
Ensembl chr13:32,702,336...32,751,458 		JBrowse link
G MOXD1 monooxygenase DBH like 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:130,073,802...130,177,753
Ensembl chr 6:134,179,412...134,285,995 		JBrowse link
G TH tyrosine hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:2,204,820...2,212,750
Ensembl chr11:2,231,248...2,242,433 		JBrowse link
octopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DBH dopamine beta-hydroxylase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:104,761,504...104,784,445
Ensembl chr 9:133,371,821...133,393,697 		JBrowse link
G MOXD1 monooxygenase DBH like 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:130,073,802...130,177,753
Ensembl chr 6:134,179,412...134,285,995 		JBrowse link
phytosphingosine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACER3 alkaline ceramidase 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:71,911,204...72,077,528
Ensembl chr11:75,557,846...75,717,586 		JBrowse link
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:7,564,164...7,720,341
Ensembl chr 6:7,848,249...8,000,649 		JBrowse link
G DAB2 DAB adaptor protein 2 ISO RGD PMID:17303656 RGD:7243836 NCBI chr 5:70,951,198...71,004,836
Ensembl chr 5:76,022,143...76,041,443 		JBrowse link
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:21,310,228...21,335,985
Ensembl chr 1:22,255,056...22,268,801 		JBrowse link
positive regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR1D1 nuclear receptor subfamily 1 group D member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:17,188,390...17,196,315
Ensembl chr17:17,409,669...17,417,600 		JBrowse link
G STAR steroidogenic acute regulatory protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:37,446,334...37,454,102
Ensembl chr 8:34,623,201...34,629,544 		JBrowse link
G STARD4 StAR related lipid transfer domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:106,855,990...106,873,384
Ensembl chr 5:112,657,516...112,675,165 		JBrowse link
positive regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3768186|PMID:17916878) BHF-UCL PMID:17916878 MGI:3768186 NCBI chr21:28,534,697...28,619,590
Ensembl chr21:41,839,115...41,933,050 		JBrowse link
G ABCG4 ATP binding cassette subfamily G member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:113,987,709...114,001,354
Ensembl chr11:117,916,043...117,929,636 		JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in ISO PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr 8:54,942,509...54,952,500
Ensembl chr 8:56,593,799...56,604,037 		JBrowse link
G FDPS farnesyl diphosphate synthase ISO RGD PMID:18637708 RGD:2316295 NCBI chr 1:130,653,316...130,665,196
Ensembl chr 1:134,258,968...134,270,237 		JBrowse link
G FGF1 fibroblast growth factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:137,949,100...138,054,553
Ensembl chr 5:144,056,387...144,078,001 		JBrowse link
G LOC100990437 NADPH--cytochrome P450 reductase ISO RGD PMID:19264869 RGD:2316785 NCBI chr 7:68,035,021...68,105,934
Ensembl chr 7:82,364,418...82,437,530 		JBrowse link
G NPY1R neuropeptide Y receptor Y1 ISO RGD PMID:32976883 RGD:405096663 NCBI chr 4:155,583,870...155,604,336
Ensembl chr 4:167,372,310...167,381,597 		JBrowse link
G QKI QKI, KH domain containing RNA binding involved_in ISO (MGI:6712091|PMID:33942715) UniProt PMID:33942715 MGI:6712091 NCBI chr 6:161,361,413...161,523,414 JBrowse link
G SCAP SREBF chaperone involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:47,314,535...47,379,455
Ensembl chr 3:48,414,012...48,479,845 		JBrowse link
G SCP2 sterol carrier protein 2 ISO RGD PMID:2554812 RGD:9850260 NCBI chr 1:52,195,491...52,324,227
Ensembl chr 1:53,797,254...53,924,939 		JBrowse link
G SEC14L2 SEC14 like lipid binding 2 ISO RGD PMID:11226224 RGD:727312 NCBI chr22:11,432,608...11,460,973
Ensembl chr22:29,234,162...29,261,937 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9329978)
(PMID:16046411)		 Ensembl
MGI		 PMID:9329978 PMID:16046411 GO_REF:0000107 NCBI chr17:33,458,196...33,484,643
Ensembl chr17:38,405,794...38,432,045 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:22,725,790...22,799,749
Ensembl chr22:40,811,459...40,884,947 		JBrowse link
positive regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:21,310,228...21,335,985
Ensembl chr 1:22,255,056...22,268,801 		JBrowse link
positive regulation of dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPAS1 endothelial PAS domain protein 1 ISO RGD PMID:19457096 RGD:5128877 NCBI chr2A:46,403,411...46,492,734
Ensembl chr2A:47,332,308...47,421,560 		JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:6,722,260...6,745,915
Ensembl chr 1:7,969,280...7,993,271 		JBrowse link
G VPS35 VPS35 retromer complex component involved_in ISO (MGI:5694519|PMID:26203154) ParkinsonsUK-UCL PMID:26203154 MGI:5694519 NCBI chr16:26,924,901...26,954,443
Ensembl chr16:45,817,371...45,846,531 		JBrowse link
positive regulation of inositol phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCYAP1R1 ADCYAP receptor type I ISO RGD PMID:8943280 RGD:2315982 NCBI chr 7:31,597,251...31,724,299
Ensembl chr 7:31,784,622...31,843,381 		JBrowse link
G AVPR1B arginine vasopressin receptor 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:181,713,548...181,723,645
Ensembl chr 1:185,999,627...186,007,043 		JBrowse link
G CD244 CD244 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:136,186,906...136,219,669
Ensembl chr 1:140,110,808...140,123,065 		JBrowse link
G MAS1 MAS1 proto-oncogene, G protein-coupled receptor ISO RGD PMID:1332507 RGD:2316794 NCBI chr 6:157,774,098...157,799,983
Ensembl chr 6:162,801,416...162,802,393 		JBrowse link
G NTSR1 neurotensin receptor 1 ISO RGD PMID:11861328 RGD:9743897 NCBI chr20:59,100,110...59,151,563
Ensembl chr20:60,392,736...60,446,056 		JBrowse link
G PTAFR platelet activating factor receptor ISO RGD PMID:8798508 RGD:9999203 NCBI chr 1:27,405,880...27,436,184
Ensembl chr 1:28,447,833...28,448,861 		JBrowse link
G PTH parathyroid hormone involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:13,653,777...13,657,901
Ensembl chr11:13,347,838...13,351,802 		JBrowse link
G PTH1R parathyroid hormone 1 receptor involved_in ISO PMID:19608645 BHF-UCL PMID:19608645 RGD:8553376 NCBI chr 3:46,777,945...46,804,039
Ensembl chr 3:47,894,901...47,905,431 		JBrowse link
G SNCA synuclein alpha involved_in ISO (PMID:15641770) UniProt PMID:15641770 NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600 		JBrowse link
positive regulation of inositol trisphosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPER1 G protein-coupled estrogen receptor 1 involved_in ISO (PMID:15705806) UniProt PMID:15705806 NCBI chr 7:1,331,586...1,338,194 JBrowse link
G LHCGR luteinizing hormone/choriogonadotropin receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:48,808,822...48,879,021
Ensembl chr2A:49,729,002...49,798,780 		JBrowse link
G MYH9 myosin heavy chain 9 ISO RGD PMID:20068007 RGD:6902910 NCBI chr22:17,200,623...17,305,826
Ensembl chr22:35,039,101...35,121,618 		JBrowse link
G P2RY1 purinergic receptor P2Y1 involved_in ISO PMID:11390975 BHF-UCL PMID:11390975 RGD:8553380 NCBI chr 3:149,859,748...149,865,873
Ensembl chr 3:157,426,692...157,427,813 		JBrowse link
G P2RY6 pyrimidinergic receptor P2Y6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:68,341,722...68,375,923
Ensembl chr11:71,594,250...71,595,236 		JBrowse link
G PLCD1 phospholipase C delta 1 ISO RGD PMID:16709602 RGD:2300424 NCBI chr 3:37,906,359...37,928,564
Ensembl chr 3:38,189,496...38,206,886 		JBrowse link
G POU1F1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO (PMID:11371619) MGI PMID:11371619 NCBI chr 3:87,390,157...87,407,611
Ensembl chr 3:89,501,298...89,521,168 		JBrowse link
positive regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:57,161,299...57,206,672
Ensembl chr 3:58,370,430...58,415,258 		JBrowse link
G ASIP agouti signaling protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:30,583,038...30,592,726
Ensembl chr20:31,718,169...31,727,217 		JBrowse link
G ATP7A ATPase copper transporting alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:67,093,675...67,231,318
Ensembl chr  X:77,255,312...77,342,756 		JBrowse link
G CDH3 cadherin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:49,015,115...49,071,903
Ensembl chr16:68,407,625...68,465,287 		JBrowse link
G GIPC1 GIPC PDZ domain containing family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:14,041,192...14,059,402
Ensembl chr19:14,885,185...14,889,701 		JBrowse link
G OPN3 opsin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:217,155,765...217,202,577
Ensembl chr 1:222,136,422...222,184,598 		JBrowse link
G PMEL premelanosome protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:32,946,951...32,958,205
Ensembl chr12:33,196,040...33,207,610 		JBrowse link
G RAB38 RAB38, member RAS oncogene family ISO RGD PMID:17043139 RGD:152025192 NCBI chr11:83,121,858...83,183,698
Ensembl chr11:86,710,358...86,773,142 		JBrowse link
G TYRP1 tyrosinase related protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:12,502,610...12,550,203
Ensembl chr 9:12,950,831...12,996,799 		JBrowse link
positive regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829 		JBrowse link
G TNF tumor necrosis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381 		JBrowse link
pyridoxal 5'-phosphate salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDXK pyridoxal kinase involved_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr21:29,977,286...30,021,266
Ensembl chr21:43,273,237...43,313,637 		JBrowse link
pyridoxal phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDXK pyridoxal kinase ISO RGD PMID:2988502 RGD:2303018 NCBI chr21:29,977,286...30,021,266
Ensembl chr21:43,273,237...43,313,637 		JBrowse link
G PNPO pyridoxamine 5'-phosphate oxidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:7489789|PMID:9601034) Ensembl
GOC
GOC		 PMID:9601034 GO_REF:0000107 GO_REF:0000108 MGI:7489789 NCBI chr17:9,589,253...9,596,973
Ensembl chr17:9,773,052...9,778,922 		JBrowse link
pyridoxine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PNPO pyridoxamine 5'-phosphate oxidase involved_in IEA InterPro GO_REF:0000002 NCBI chr17:9,589,253...9,596,973
Ensembl chr17:9,773,052...9,778,922 		JBrowse link
regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLCN2 chloride voltage-gated channel 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:181,383,608...181,399,200
Ensembl chr 3:189,862,489...189,881,049 		JBrowse link
regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:54,942,509...54,952,500
Ensembl chr 8:56,593,799...56,604,037 		JBrowse link
G FGFR4 fibroblast growth factor receptor 4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:172,386,443...172,400,271
Ensembl chr 5:179,454,995...179,467,605 		JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069 		JBrowse link
regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 NOT|involved_in ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chr 9:108,067,633...108,089,742
Ensembl chr 9:137,036,696...137,057,776 		JBrowse link
G APOB apolipoprotein B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16455790) Ensembl
MGI		 PMID:16455790 GO_REF:0000107 NCBI chr2A:20,986,464...21,029,004
Ensembl chr2A:21,100,356...21,145,129 		JBrowse link
G AQP8 aquaporin 8 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:25,458,165...25,469,713 JBrowse link
G DHCR7 7-dehydrocholesterol reductase ISO RGD PMID:10329655 RGD:632010 NCBI chr11:66,450,230...66,464,214
Ensembl chr11:69,721,741...69,735,715 		JBrowse link
G ERLIN1 ER lipid raft associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:96,756,261...96,791,925
Ensembl chr10:100,238,320...100,273,942 		JBrowse link
G ERLIN2 ER lipid raft associated 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:37,034,391...37,057,164
Ensembl chr 8:34,212,704...34,233,583 		JBrowse link
G LPCAT3 lysophosphatidylcholine acyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:7,107,925...7,149,982
Ensembl chr12:7,024,015...7,065,945 		JBrowse link
G PEX2 peroxisomal biogenesis factor 2 acts_upstream_of_or_within ISO (PMID:14673138) MGI PMID:14673138 NCBI chr 8:73,508,349...73,526,560
Ensembl chr 8:75,146,255...75,147,172 		JBrowse link
G SCAP SREBF chaperone involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16054043) Ensembl
MGI
TreeGrafter		 PMID:16054043 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:47,314,535...47,379,455
Ensembl chr 3:48,414,012...48,479,845 		JBrowse link
regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DGKQ diacylglycerol kinase theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:1,075,133...1,090,081
Ensembl chr 4:994,985...1,007,724 		JBrowse link
G H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:7,996,315...8,031,987
Ensembl chr 1:9,232,666...9,256,631 		JBrowse link
regulation of dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH2 aldehyde dehydrogenase 2 family member involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:109,343,020...109,385,060
Ensembl chr12:112,734,243...112,776,471 		JBrowse link
regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTNS cystinosin, lysosomal cystine transporter involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:3,686,903...3,711,857
Ensembl chr17:3,683,575...3,708,253 		JBrowse link
G MFSD12 major facilitator superfamily domain containing 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:2,570,068...2,583,505
Ensembl chr19:3,520,399...3,532,767 		JBrowse link
G SLC7A11 solute carrier family 7 member 11 acts_upstream_of_or_within ISO (PMID:16037214) MGI PMID:16037214 NCBI chr 4:130,529,677...130,601,396
Ensembl chr 4:141,849,343...141,959,849 		JBrowse link
regulation of serotonin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH2 aldehyde dehydrogenase 2 family member involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:109,343,020...109,385,060
Ensembl chr12:112,734,243...112,776,471 		JBrowse link
regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C3 aldo-keto reductase family 1 member C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:5,079,580...5,157,572
Ensembl chr10:5,081,214...5,139,812 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein involved_in ISO (MGI:4947864|PMID:21333348)
(PMID:21333348)		 UniProt PMID:21333348 MGI:4947864 NCBI chr 1:131,583,789...131,586,459
Ensembl chr 1:135,413,871...135,416,432 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:94,762,796...94,836,304
Ensembl chr2B:212,891,261...212,958,130 		JBrowse link
G GPRC6A G protein-coupled receptor class C group 6 member A involved_in ISO (MGI:4947864|PMID:21333348)
(PMID:21333348)		 UniProt PMID:21333348 MGI:4947864 NCBI chr 6:114,601,360...114,638,286
Ensembl chr 6:118,744,929...118,781,099 		JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 ISO RGD PMID:22429315 RGD:7775068 NCBI chr10:47,642,312...48,935,188
Ensembl chr10:49,779,211...51,064,882 		JBrowse link
serotonin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDC dopa decarboxylase involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:10027744 GO_REF:0000118 RGD:5129182 NCBI chr 7:51,101,169...51,206,031
Ensembl chr 7:51,345,228...51,449,710 		JBrowse link
G TPH1 tryptophan hydroxylase 1 involved_in IEA UniProt
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 NCBI chr11:18,070,576...18,099,539
Ensembl chr11:17,754,893...17,778,076 		JBrowse link
G TPH2 tryptophan hydroxylase 2 involved_in IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000041 GO_REF:0000043 NCBI chr12:69,460,883...69,557,329
Ensembl chr12:72,318,908...72,412,557 		JBrowse link
serotonin biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100988273 cytochrome P450 2D6-like ISO RGD PMID:23098818 RGD:11353778 NCBI chr22:23,022,449...23,031,627 JBrowse link
sorbitol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1B1 aldo-keto reductase family 1 member B ISO RGD PMID:6690344 PMID:21376710 RGD:1626096 RGD:8548687 NCBI chr 7:126,400,861...126,417,756
Ensembl chr 7:138,912,953...138,924,095 		JBrowse link
sphinganine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPTLC1 serine palmitoyltransferase long chain base subunit 1 acts_upstream_of_or_within ISO (PMID:19416652) MGI PMID:19416652 NCBI chr 9:63,087,798...63,174,977 JBrowse link
G SPTLC2 serine palmitoyltransferase long chain base subunit 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9363775) Ensembl
MGI		 PMID:9363775 GO_REF:0000107 NCBI chr14:58,066,123...58,170,472
Ensembl chr14:77,266,545...77,370,663 		JBrowse link
sphingosine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of_positive_effect
involved_in		 ISO
IEA		 (PMID:26510981) ARUK-UCL
Ensembl		 PMID:26510981 GO_REF:0000107 NCBI chr 9:108,067,633...108,089,742
Ensembl chr 9:137,036,696...137,057,776 		JBrowse link
G ACER1 alkaline ceramidase 1 involved_in IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chr19:5,327,251...5,393,587
Ensembl chr19:6,252,300...6,281,016 		JBrowse link
G ACER2 alkaline ceramidase 2 involved_in IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chr 9:19,216,891...19,262,477
Ensembl chr 9:19,709,402...19,750,896 		JBrowse link
G ACER3 alkaline ceramidase 3 involved_in IEA Ensembl
UniProt		 GO_REF:0000107 GO_REF:0000117 NCBI chr11:71,911,204...72,077,528
Ensembl chr11:75,557,846...75,717,586 		JBrowse link
G AGK acylglycerol kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:133,438,436...133,580,423
Ensembl chr 7:145,948,154...146,050,512 		JBrowse link
G ASAH1 N-acylsphingosine amidohydrolase 1 involved_in ISO (PMID:12815059)
(MGI:1267186|PMID:9653654)
(PMID:10610716)		 UniProt PMID:9653654 PMID:10610716 PMID:12815059 MGI:1267186 NCBI chr 8:17,272,632...17,300,902 JBrowse link
G GBA1 glucosylceramidase beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:130,579,300...130,589,560
Ensembl chr 1:134,185,385...134,194,851 		JBrowse link
G LOC100985247 putative inactive neutral ceramidase B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:46,842,830...46,908,811
Ensembl chr10:48,969,434...49,025,336 		JBrowse link
G SPHK1 sphingosine kinase 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:70,331,370...70,336,043
Ensembl chr17:75,883,329...75,886,481 		JBrowse link
G SPHK2 sphingosine kinase 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr19:45,620,980...45,631,786
Ensembl chr19:54,213,166...54,224,767 		JBrowse link
G SPTLC1 serine palmitoyltransferase long chain base subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16216550) TreeGrafter
MGI		 PMID:16216550 GO_REF:0000118 NCBI chr 9:63,087,798...63,174,977 JBrowse link
G SPTLC2 serine palmitoyltransferase long chain base subunit 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16216550) Ensembl
MGI
TreeGrafter		 PMID:16216550 GO_REF:0000107 GO_REF:0000118 NCBI chr14:58,066,123...58,170,472
Ensembl chr14:77,266,545...77,370,663 		JBrowse link
G SPTLC3 serine palmitoyltransferase long chain base subunit 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:12,966,584...13,125,802
Ensembl chr20:12,952,524...13,111,347 		JBrowse link
G SPTSSA serine palmitoyltransferase small subunit A involved_in ISO (PMID:19416851), (PMID:33558761) ComplexPortal PMID:19416851 PMID:33558761 NCBI chr14:15,190,833...15,219,882 JBrowse link
G SPTSSB serine palmitoyltransferase small subunit B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:158,358,718...158,385,625
Ensembl chr 3:166,406,488...166,406,718 		JBrowse link
sterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CH25H cholesterol 25-hydroxylase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:85,930,638...85,932,065
Ensembl chr10:89,471,441...89,472,259 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15005800) UniProt
MGI
InterPro		 PMID:15005800 GO_REF:0000002 GO_REF:0000043 NCBI chr11:66,450,230...66,464,214
Ensembl chr11:69,721,741...69,735,715 		JBrowse link
G EBP EBP cholestenol delta-isomerase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10391218) UniProt
MGI		 PMID:10391218 GO_REF:0000043 NCBI chr  X:40,820,042...40,826,957 JBrowse link
G FAXDC2 fatty acid hydroxylase domain containing 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:150,222,289...150,255,055
Ensembl chr 5:156,217,594...156,249,567 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase involved_in IEA UniProt GO_REF:0000043 NCBI chr 5:39,936,630...39,961,519
Ensembl chr 5:40,548,919...40,573,785 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 5:67,067,001...67,091,786
Ensembl chr 5:72,116,228...72,141,050 		JBrowse link
G HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:82,778,489...82,798,987
Ensembl chr 1:117,775,770...117,796,679 		JBrowse link
G IDI1 isopentenyl-diphosphate delta isomerase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr10:1,078,107...1,087,054
Ensembl chr10:1,124,920...1,133,234 		JBrowse link
G IDI2 isopentenyl-diphosphate delta isomerase 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr10:1,056,280...1,062,070
Ensembl chr10:1,102,655...1,108,246 		JBrowse link
G INSIG1 insulin induced gene 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16955138) Ensembl
MGI		 PMID:16955138 GO_REF:0000107 NCBI chr 7:146,893,730...146,906,329
Ensembl chr 7:158,619,531...158,632,012 		JBrowse link
G INSIG2 insulin induced gene 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16955138) Ensembl
MGI		 PMID:16955138 GO_REF:0000107 NCBI chr2B:5,046,971...5,068,757
Ensembl chr2B:118,632,402...118,652,647 		JBrowse link
G LBR lamin B receptor involved_in IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr 1:200,865,602...200,892,199
Ensembl chr 1:205,870,394...205,893,032 		JBrowse link
G MSMO1 methylsterol monooxygenase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 4:157,523,099...157,538,508
Ensembl chr 4:169,606,809...169,622,212 		JBrowse link
G MVD mevalonate diphosphate decarboxylase involved_in IEA UniProt GO_REF:0000043 NCBI chr16:69,365,070...69,376,149
Ensembl chr16:89,025,572...89,036,964 		JBrowse link
G MVK mevalonate kinase involved_in IEA UniProt GO_REF:0000043 NCBI chr12:107,150,477...107,173,978
Ensembl chr12:110,544,991...110,568,524 		JBrowse link
G PMVK phosphomevalonate kinase involved_in IEA Ensembl
UniProt		 GO_REF:0000043 GO_REF:0000107 NCBI chr 1:130,273,246...130,286,614
Ensembl chr 1:133,882,840...133,894,818 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 5:69,581,748...69,620,721
Ensembl chr 5:74,627,830...74,666,505 		JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:55,928,577...55,998,628
Ensembl chr 1:57,664,237...57,702,227 		JBrowse link
G SC5D sterol-C5-desaturase involved_in IEA UniProt GO_REF:0000043 NCBI chr11:116,139,979...116,160,745
Ensembl chr11:120,063,743...120,078,386 		JBrowse link
G SQLE squalene epoxidase involved_in IEA UniProt
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 NCBI chr 8:121,684,269...121,708,131
Ensembl chr 8:124,435,668...124,459,441 		JBrowse link
G TM7SF2 transmembrane 7 superfamily member 2 involved_in IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr11:60,473,934...60,478,579
Ensembl chr11:63,812,769...63,816,812 		JBrowse link
testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C3 aldo-keto reductase family 1 member C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:5,079,580...5,157,572
Ensembl chr10:5,081,214...5,139,812 		JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 ISO RGD PMID:19883722 RGD:4145609 NCBI chr15:53,280,110...53,310,868
Ensembl chr15:72,901,286...72,931,164 		JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 acts_upstream_of_or_within ISO (PMID:9618522) MGI PMID:9618522 NCBI chr15:30,152,924...30,282,854
Ensembl chr15:48,486,688...48,521,554 		JBrowse link
G HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 involved_in ISO (MGI:1267145|PMID:9658408) RGD
UniProt		 PMID:8612487 PMID:9658408 MGI:1267145 RGD:728619 NCBI chr17:14,760,856...14,763,584
Ensembl chr17:14,986,814...14,988,820 		JBrowse link
G SRD5A2 steroid 5 alpha-reductase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:31,542,646...31,597,394
Ensembl chr2A:31,610,487...31,665,718 		JBrowse link
G STAR steroidogenic acute regulatory protein ISO RGD PMID:19883722 RGD:4145609 NCBI chr 8:37,446,334...37,454,102
Ensembl chr 8:34,623,201...34,629,544 		JBrowse link
tetrahydrobiopterin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHFR dihydrofolate reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:34,663,210...34,689,467
Ensembl chr 5:34,938,548...34,967,003 		JBrowse link
G GCH1 GTP cyclohydrolase 1 involved_in IEA UniProt
TreeGrafter
Ensembl		 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr14:35,428,676...35,489,359
Ensembl chr14:53,706,723...53,767,393 		JBrowse link
G PCBD1 pterin-4 alpha-carbinolamine dehydratase 1 involved_in IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr10:67,353,903...67,359,073
Ensembl chr10:69,878,773...69,881,174 		JBrowse link
G PCBD2 pterin-4 alpha-carbinolamine dehydratase 2 involved_in IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr 5:130,303,900...130,364,899
Ensembl chr 5:136,446,730...136,497,011 		JBrowse link
G PTS 6-pyruvoyltetrahydropterin synthase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9894812) Ensembl
MGI
UniProt
InterPro		 PMID:9894812 GO_REF:0000002 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 NCBI chr11:107,107,114...107,114,594
Ensembl chr11:110,949,708...110,957,599 		JBrowse link
G QDPR quinoid dihydropteridine reductase involved_in ISO
IEA		 RGD
TreeGrafter
UniProt		 PMID:660556 PMID:9235988 GO_REF:0000043 GO_REF:0000118 RGD:4139903 RGD:5128582 NCBI chr 4:11,906,439...11,932,311
Ensembl chr 4:17,199,772...17,225,667 		JBrowse link
G SPR sepiapterin reductase involved_in ISO
IEA		 RGD
TreeGrafter
InterPro		 PMID:2179471 GO_REF:0000002 GO_REF:0000118 RGD:1600056 NCBI chr2A:72,939,621...72,944,669
Ensembl chr2A:74,433,056...74,438,105 		JBrowse link
vitamin E biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLTP phospholipid transfer protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16467369) Ensembl
MGI		 PMID:16467369 GO_REF:0000107 NCBI chr20:42,237,434...42,251,189
Ensembl chr20:43,324,609...43,337,999 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16313
    metabolic process 10179
      biosynthetic process 7255
        organic substance biosynthetic process 7193
          organic hydroxy compound biosynthetic process 233
            (R)-2-hydroxy-alpha-linolenic acid biosynthetic process 0
            (R)-mevalonic acid biosynthetic process + 0
            (S)-reticuline biosynthetic process 0
            achromobactin biosynthetic process 0
            ajmaline biosynthetic process 0
            alcohol biosynthetic process + 139
            andrastin A biosynthetic process 0
            berbamunine biosynthetic process 0
            bile acid biosynthetic process + 25
            brexanolone biosynthetic process 0
            flavonol biosynthetic process + 1
            fumigermin biosynthetic process 0
            glycyrrhetinate biosynthetic process 0
            isopentenol biosynthetic process 0
            kaempferol O-glucoside biosynthetic process 0
            lactate biosynthetic process + 5
            leucoanthocyanidin biosynthetic process 0
            leukotriene B4 biosynthetic process 0
            lipoxin A4 biosynthetic process 3
            lipoxin B4 biosynthetic process 1
            luteolin biosynthetic process 0
            mandelate biosynthetic process 0
            phenol-containing compound biosynthetic process + 52
            phytosteroid biosynthetic process + 12
            pyridoxal biosynthetic process 0
            pyridoxal phosphate biosynthetic process + 2
            pyridoxine biosynthetic process 1
            quercetin biosynthetic process 0
            sterol biosynthetic process + 57
            terrequinone A biosynthetic process + 0
            testosterone biosynthetic process + 12
            vitamin D biosynthetic process + 8
            vitamin E biosynthetic process + 1
paths to the root