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ONTOLOGY REPORT - ANNOTATIONS


Term:alpha-amino acid biosynthetic process
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Accession:GO:1901607 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of an alpha-amino acid.
Synonyms:exact_synonym: alpha-amino acid anabolism;   alpha-amino acid biosynthesis;   alpha-amino acid formation;   alpha-amino acid synthesis



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arginine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asl argininosuccinate lyase NAS RGD PMID:2789519 RGD:632221 NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662
JBrowse link
G Ass1 argininosuccinate synthase 1 involved_in IDA
IBA
IMP
ISO
IEA
PMID:21873635
PMID:19491403
(PMID:18473344), (PMID:27287393), (PMID:8792870)
GO_REF:0000041
RGD
UniProt
PMID:8792870 PMID:18473344 PMID:27287393 PMID:12470967 PMID:21873635 More... GO_REF:0000041, RGD:631755, RGD:13792537, RGD:12859071 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
JBrowse link
G Nags N-acetylglutamate synthase involved_in IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr10:87,098,330...87,102,465
Ensembl chr10:87,098,330...87,102,465
JBrowse link
arginine biosynthetic process via ornithine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asl argininosuccinate lyase involved_in IEA
IBA
GO_REF:0000002
PMID:21873635
InterPro PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662
JBrowse link
G Otc ornithine transcarbamylase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:12,453,834...12,529,954
Ensembl chr  X:12,453,834...12,566,918
JBrowse link
asparagine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asns asparagine synthetase (glutamine-hydrolyzing) acts_upstream_of_or_within
involved_in
IDA
ISO
IBA
(PMID:2573597)
PMID:21873635
RGD PMID:2573597 PMID:2887559 PMID:21873635 RGD:2316002, RGD:13792537 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Asnsd1 asparagine synthetase domain containing 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:48,126,802...48,139,073
Ensembl chr 9:48,126,808...48,139,073
JBrowse link
aspartate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:53641|PMID:4193185)
RGD PMID:4193185 PMID:21873635 MGI:53641, RGD:13792537 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Got1l1 glutamic-oxaloacetic transaminase 1-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:64,860,308...64,873,656
Ensembl chr16:64,860,704...64,866,162
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within ISO (MGI:53641|PMID:4193185) RGD PMID:4193185 MGI:53641 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
JBrowse link
citrulline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 involved_in ISO (PMID:11092761), (PMID:26297558) RGD PMID:11092761 PMID:26297558 NCBI chr 1:239,375,657...239,407,967
Ensembl chr 1:239,375,669...239,407,890
JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:7053379 PMID:21873635 RGD:10755426, RGD:13792537 NCBI chr 6:25,292,133...25,315,176
Ensembl chr 6:25,292,133...25,319,861
JBrowse link
G Otc ornithine transcarbamylase involved_in IDA
ISO
IBA
(PMID:2556444), (PMID:8112735)
PMID:21873635
RGD PMID:2556444 PMID:8112735 PMID:9472964 PMID:21873635 RGD:4144071, RGD:13792537 NCBI chr  X:12,453,834...12,529,954
Ensembl chr  X:12,453,834...12,566,918
JBrowse link
cysteine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:24416422)
PMID:21873635
MGI:1857139 (MGI:3044255|PMID:15030387)
RGD PMID:15030387 PMID:24416422 PMID:21873635 MGI:3044255, RGD:13792537 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
JBrowse link
G Cth cystathionine gamma-lyase involved_in IDA
ISS
ISO
IEA
GO_REF:0000024
(PMID:10212249)
GO_REF:0000041
UniProt
RGD
PMID:10212249 PMID:9359866 GO_REF:0000024 GO_REF:0000041, RGD:1359024 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 involved_in ISO
IEA
(MGI:5294309|PMID:12468440)
GO_REF:0000107
RGD
Ensembl
PMID:12468440 GO_REF:0000107 MGI:5294309 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
cysteine biosynthetic process from serine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase TAS RGD PMID:9359866 RGD:1359024 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
JBrowse link
cysteine biosynthetic process via cystathionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
JBrowse link
G Cth cystathionine gamma-lyase involved_in IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:19428278)
Ensembl
RGD
PMID:19428278 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
JBrowse link
D-serine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Srr serine racemase involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:11054547), (PMID:15193426)
(MGI:1347751|PMID:10557334), (MGI:1926659|PMID:11054547), (MGI:2183617|PMID:12021263), (MGI:3529732|PMID:15710237)
PMID:21873635
RGD PMID:10557334 PMID:11054547 PMID:12021263 PMID:15193426 PMID:15710237 More... MGI:1347751 MGI:1926659 MGI:2183617 MGI:3529732, RGD:13792537 NCBI chr10:59,769,563...59,786,688
Ensembl chr10:59,769,571...59,787,011
JBrowse link
glutamate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gls glutaminase involved_in IEA
ISO
IBA
ISS
GO_REF:0000107
(MGI:5320252|PMID:22228304)
PMID:21873635
GO_REF:0000024
(PMID:16899818), (PMID:22049910)
Ensembl
RGD
UniProt
PMID:16899818 PMID:22049910 PMID:22228304 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5320252, RGD:13792537 NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900
JBrowse link
G Gls2 glutaminase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:617,252...633,424
Ensembl chr 7:617,288...633,426
JBrowse link
G Glud1 glutamate dehydrogenase 1 involved_in ISO (PMID:11032875) RGD PMID:11032875 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
JBrowse link
G Slc25a12 solute carrier family 25 member 12 IMP RGD PMID:19764902 RGD:13628741 NCBI chr 3:56,098,080...56,192,188
Ensembl chr 3:56,097,269...56,192,100
JBrowse link
glutamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glul glutamate-ammonia ligase involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:4403443 PMID:21873635 PMID:28323 RGD:2301548, RGD:13792537, RGD:2301547 NCBI chr13:65,969,064...66,035,121
Ensembl chr13:66,025,630...66,035,108
JBrowse link
G Lgsn lengsin, lens protein with glutamine synthetase domain NOT|involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:33,416,362...33,447,919
Ensembl chr 9:33,420,484...33,447,907
JBrowse link
glycine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhfr dihydrofolate reductase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
JBrowse link
G LOC688286 similar to threonine aldolase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:103,094,681...103,100,169
Ensembl chr10:103,094,681...103,100,519
JBrowse link
G Sardh sarcosine dehydrogenase TAS RGD PMID:9839943 RGD:634034 NCBI chr 3:10,510,553...10,575,342
Ensembl chr 3:10,510,553...10,573,874
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 IDA from L-allothreonine in the absence of tetrahydrofolate RGD PMID:3110140 RGD:2300383 NCBI chr10:45,468,698...45,497,820
Ensembl chr10:45,468,700...45,497,820
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 IDA from L-allothreonine in the absence of tetrahydrofolate RGD PMID:3110140 RGD:2300383 NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236
JBrowse link
glycine biosynthetic process from serine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shmt1 serine hydroxymethyltransferase 1 involved_in IDA
IBA
in the presence of tetrahydrofolate
PMID:21873635
RGD
GO_Central
PMID:3110140 PMID:21873635 RGD:2300383, RGD:13792537 NCBI chr10:45,468,698...45,497,820
Ensembl chr10:45,468,700...45,497,820
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 involved_in IDA
IBA
in the presence of tetrahydrofolate
PMID:21873635
RGD
GO_Central
PMID:3110140 PMID:21873635 RGD:2300383, RGD:13792537 NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236
JBrowse link
glycine biosynthetic process, by transamination of glyoxylate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agxt alanine--glyoxylate and serine--pyruvate aminotransferase involved_in IDA
ISO
IBA
(PMID:22198249)
PMID:21873635
RGD PMID:22198249 PMID:12383475 PMID:21873635 RGD:1599457, RGD:13792537 NCBI chr 9:93,675,384...93,685,337
Ensembl chr 9:93,675,384...93,685,336
JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 involved_in ISO (PMID:20018850) RGD PMID:20018850 NCBI chr 2:59,336,252...59,377,664
Ensembl chr 2:59,336,283...59,377,926
JBrowse link
hydroxylysine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 involved_in ISO
IEA
(PMID:10934207)
GO_REF:0000107
RGD
Ensembl
PMID:10934207 GO_REF:0000107 NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255
JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 involved_in ISO (MGI:6202004|PMID:16447251) RGD PMID:16447251 MGI:6202004 NCBI chr12:19,676,384...19,686,945
Ensembl chr12:19,676,386...19,686,960
JBrowse link
isoleucine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ilvbl ilvB acetolactate synthase like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:11,039,870...11,049,924
Ensembl chr 7:11,039,871...11,049,924
JBrowse link
G Sds serine dehydratase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203
JBrowse link
G Sdsl serine dehydratase-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:36,099,693...36,109,914
Ensembl chr12:36,099,693...36,109,906
JBrowse link
L-asparagine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asns asparagine synthetase (glutamine-hydrolyzing) involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
L-methionine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase involved_in ISO
IEA
(PMID:18230605)
GO_REF:0000107
RGD
Ensembl
PMID:18230605 GO_REF:0000107 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:18230605)
Ensembl
RGD
PMID:18230605 GO_REF:0000107 NCBI chr 2:24,895,525...24,912,475
Ensembl chr 2:24,895,533...24,912,475
JBrowse link
L-methionine salvage from methylthioadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 involved_in IEA
ISS
ISO
GO_REF:0000041
GO_REF:0000024
(PMID:15938715)
UniProt
RGD
PMID:15938715 GO_REF:0000024 GO_REF:0000041 NCBI chr 6:45,306,885...45,313,847
Ensembl chr 6:45,306,841...45,313,842
JBrowse link
G Apip APAF1 interacting protein involved_in IEA
IBA
ISO
GO_REF:0000041
PMID:21873635
(PMID:22837397), (PMID:23285211)
UniProt
RGD
PMID:22837397 PMID:23285211 PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 3:89,431,973...89,457,999
Ensembl chr 3:89,432,037...89,458,340
JBrowse link
G Enoph1 enolase-phosphatase 1 involved_in IEA
ISO
IBA
ISS
GO_REF:0000041
(PMID:15843022)
PMID:21873635
GO_REF:0000024
UniProt
RGD
PMID:15843022 PMID:21873635 GO_REF:0000024 GO_REF:0000041, RGD:13792537 NCBI chr14:9,531,336...9,557,797
Ensembl chr14:9,531,339...9,569,273
JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 involved_in IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr19:23,907,335...23,913,320
Ensembl chr19:23,907,335...23,913,320
JBrowse link
G Mtap methylthioadenosine phosphorylase involved_in IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 5:103,873,020...103,939,406
Ensembl chr 5:103,873,020...103,939,406
JBrowse link
L-methionine salvage from S-adenosylmethionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apip APAF1 interacting protein involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:89,431,973...89,457,999
Ensembl chr 3:89,432,037...89,458,340
JBrowse link
G Enoph1 enolase-phosphatase 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr14:9,531,336...9,557,797
Ensembl chr14:9,531,339...9,569,273
JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr19:23,907,335...23,913,320
Ensembl chr19:23,907,335...23,913,320
JBrowse link
L-proline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:239,375,657...239,407,967
Ensembl chr 1:239,375,669...239,407,890
JBrowse link
G Noxred1 NADP-dependent oxidoreductase domain containing 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:106,862,350...106,888,113
Ensembl chr 6:106,862,343...106,884,712
JBrowse link
G Oat ornithine aminotransferase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 involved_in IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr10:105,917,732...105,922,658
Ensembl chr10:105,917,680...105,922,549
JBrowse link
G Pycr2 pyrroline-5-carboxylate reductase 2 involved_in IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr13:92,626,462...92,630,256
Ensembl chr13:92,626,471...92,634,184
JBrowse link
G Pycr3 pyrroline-5-carboxylate reductase 3 involved_in IBA
ISS
ISO
IEA
PMID:21873635
GO_REF:0000024
(PMID:23024808)
GO_REF:0000041
UniProt
RGD
PMID:23024808 PMID:21873635 GO_REF:0000024 GO_REF:0000041, RGD:13792537 NCBI chr 7:107,603,543...107,608,831 JBrowse link
L-serine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Phgdh phosphoglycerate dehydrogenase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:185,906,964...185,936,160
Ensembl chr 2:185,906,966...185,935,944
JBrowse link
G Psat1 phosphoserine aminotransferase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682
JBrowse link
G Psph phosphoserine phosphatase involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:14673469)
UniProt
RGD
PMID:14673469 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr12:26,882,524...26,905,084
Ensembl chr12:26,883,133...26,905,074
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 IDA RGD PMID:10457370 RGD:2300380 NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236
JBrowse link
leucine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcat1 branched chain amino acid transaminase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:11733007 PMID:21873635 RGD:1582175, RGD:13792537 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007
JBrowse link
lysine biosynthetic process via aminoadipic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aasdhppt aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:1,453,226...1,463,990
Ensembl chr 8:1,452,282...1,463,966
JBrowse link
G Aass aminoadipate-semialdehyde synthase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136
JBrowse link
methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase acts_upstream_of_or_within IDA
ISO
(MGI:3510291|PMID:15217352) RGD PMID:15217352 PMID:15845641 MGI:3510291, RGD:1359026 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:25633902) RGD PMID:25633902 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372
JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:17,089,947...17,170,036
Ensembl chr14:17,089,952...17,170,112
JBrowse link
G Mthfr methylenetetrahydrofolate reductase involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2385823 (MGI:3510291|PMID:15217352)
RGD PMID:15217352 PMID:21873635 MGI:3510291, RGD:13792537 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase acts_upstream_of_or_within
involved_in
IDA
ISO
IEA
MGI:2180496 (MGI:1930456|PMID:11158293)
GO_REF:0000107
(PMID:23825108)
RGD
Ensembl
PMID:11158293 PMID:23825108 PMID:15845641 PMID:11730351 GO_REF:0000107 MGI:1930456, RGD:1359026, RGD:1601423 NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822
JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISO
IBA
(PMID:11466310)
(MGI:3710265|PMID:17369066)
PMID:21873635
RGD PMID:11466310 PMID:17369066 PMID:21873635 MGI:3710265, RGD:13792537 NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425
JBrowse link
negative regulation of citrulline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 involved_in ISO (PMID:19278978) RGD PMID:19278978 NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246
JBrowse link
ornithine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 involved_in ISO (PMID:11092761), (PMID:26297558) RGD PMID:11092761 PMID:26297558 NCBI chr 1:239,375,657...239,407,967
Ensembl chr 1:239,375,669...239,407,890
JBrowse link
positive regulation of L-dopa biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:16731528)
Ensembl
ParkinsonsUK-UCL
RGD
PMID:16731528 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
proline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 involved_in ISO (PMID:11092761), (PMID:26297558) RGD PMID:11092761 PMID:26297558 NCBI chr 1:239,375,657...239,407,967
Ensembl chr 1:239,375,669...239,407,890
JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 involved_in ISO (PMID:16730026) RGD PMID:16730026 NCBI chr10:105,917,732...105,922,658
Ensembl chr10:105,917,680...105,922,549
JBrowse link
G Pycr2 pyrroline-5-carboxylate reductase 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:23024808)
UniProt
RGD
PMID:23024808 GO_REF:0000024 NCBI chr13:92,626,462...92,630,256
Ensembl chr13:92,626,471...92,634,184
JBrowse link
regulation of arginine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (MGI:4830440|PMID:19284480) RGD PMID:19284480 MGI:4830440 NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434
JBrowse link
selenocysteine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sephs1 selenophosphate synthetase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:73,354,435...73,382,803
Ensembl chr17:73,356,530...73,382,593
JBrowse link
G Sephs2 selenophosphate synthetase 2 acts_upstream_of_or_within ISO (MGI:3711593|PMID:17346238) RGD PMID:17346238 MGI:3711593 NCBI chr 1:181,893,146...181,895,464
Ensembl chr 1:181,892,599...181,895,497
JBrowse link
serine family amino acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:25633902) RGD PMID:25633902 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372
JBrowse link
G Phgdh phosphoglycerate dehydrogenase TAS RGD PMID:9163325 RGD:61693 NCBI chr 2:185,906,964...185,936,160
Ensembl chr 2:185,906,966...185,935,944
JBrowse link
threonine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Thnsl2 threonine synthase-like 2 NOT|acts_upstream_of_or_within ISO (MGI:3690523|PMID:17034760) RGD PMID:17034760 MGI:3690523 NCBI chr 4:103,112,974...103,132,122
Ensembl chr 4:103,112,963...103,132,017
JBrowse link
tyrosine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pah phenylalanine hydroxylase involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:16953590 PMID:21873635 RGD:1601531, RGD:13792537 NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130
JBrowse link
tyrosine biosynthetic process, by oxidation of phenylalanine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pah phenylalanine hydroxylase involved_in IDA
IEA
GO_REF:0000108 GOC
RGD
PMID:10839989 GO_REF:0000108, RGD:1601535 NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130
JBrowse link
G Pcbd1 pterin-4 alpha-carbinolamine dehydratase 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr20:29,037,545...29,044,322
Ensembl chr20:28,953,864...29,044,292
Ensembl chr20:28,953,864...29,044,292
JBrowse link
G Pcbd2 pterin-4 alpha-carbinolamine dehydratase 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr17:8,845,161...8,896,343 JBrowse link
valine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcat1 branched chain amino acid transaminase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007
JBrowse link
G Ilvbl ilvB acetolactate synthase like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:11,039,870...11,049,924
Ensembl chr 7:11,039,871...11,049,924
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      primary metabolic process 10535
        cellular amino acid metabolic process 277
          alpha-amino acid metabolic process 199
            alpha-amino acid biosynthetic process 66
              1-aminocyclopropane-1-carboxylate biosynthetic process 0
              3-cyano-L-alanine biosynthetic process 0
              4-hydroxyproline biosynthetic process 0
              D-amino acid biosynthetic process + 1
              L-beta-ethynylserine biosynthetic process 0
              L-dopa biosynthetic process + 1
              L-propargylglycine biosynthetic process 0
              N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthetic process + 0
              aspartate family amino acid biosynthetic process + 22
              citrulline biosynthetic process + 4
              discadenine biosynthetic process 0
              erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process + 0
              glutamine family amino acid biosynthetic process + 17
              homocysteine biosynthetic process + 0
              isoleucine biosynthetic process + 3
              leucine biosynthetic process + 2
              ornithine biosynthetic process 1
              phosphoarginine biosynthetic process 0
              pyruvate family amino acid biosynthetic process + 0
              sarcosine biosynthetic process 0
              serine family amino acid biosynthetic process + 17
              stachydrine biosynthetic process 0
              tryptophan biosynthetic process 0
              tyrosine biosynthetic process + 3
              valine biosynthetic process 3
Path 2
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      organic substance metabolic process 11355
        organic acid metabolic process 1013
          oxoacid metabolic process 982
            carboxylic acid metabolic process 961
              carboxylic acid biosynthetic process 295
                cellular amino acid biosynthetic process 72
                  alpha-amino acid biosynthetic process 66
                    1-aminocyclopropane-1-carboxylate biosynthetic process 0
                    3-cyano-L-alanine biosynthetic process 0
                    4-hydroxyproline biosynthetic process 0
                    D-amino acid biosynthetic process + 1
                    L-beta-ethynylserine biosynthetic process 0
                    L-dopa biosynthetic process + 1
                    L-propargylglycine biosynthetic process 0
                    N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthetic process + 0
                    aspartate family amino acid biosynthetic process + 22
                    citrulline biosynthetic process + 4
                    discadenine biosynthetic process 0
                    erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process + 0
                    glutamine family amino acid biosynthetic process + 17
                    homocysteine biosynthetic process + 0
                    isoleucine biosynthetic process + 3
                    leucine biosynthetic process + 2
                    ornithine biosynthetic process 1
                    phosphoarginine biosynthetic process 0
                    pyruvate family amino acid biosynthetic process + 0
                    sarcosine biosynthetic process 0
                    serine family amino acid biosynthetic process + 17
                    stachydrine biosynthetic process 0
                    tryptophan biosynthetic process 0
                    tyrosine biosynthetic process + 3
                    valine biosynthetic process 3
paths to the root