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ONTOLOGY REPORT - ANNOTATIONS


Term:alpha-amino acid biosynthetic process
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Accession:GO:1901607 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of an alpha-amino acid.
Synonyms:exact_synonym: alpha-amino acid anabolism;   alpha-amino acid biosynthesis;   alpha-amino acid formation;   alpha-amino acid synthesis


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1-aminocyclopropane-1-carboxylate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Accs 1-aminocyclopropane-1-carboxylate synthase IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:82,742,830...82,757,273
Ensembl chr 3:82,742,831...82,757,204
JBrowse link
arginine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asl argininosuccinate lyase NAS RGD PMID:2789519 RGD:632221 NCBI chr12:30,160,922...30,178,348
Ensembl chr12:30,165,694...30,178,341
JBrowse link
G Ass1 argininosuccinate synthase 1 IDA
IBA
ISO
IMP
IEA
PMID:21873635
(PMID:18473344), (PMID:27287393), (PMID:8792870)
PMID:19491403
GO_REF:0000041
RGD
UniProt
PMID:8792870, PMID:18473344, PMID:27287393, PMID:12470967, PMID:21873635, PMID:19491403 GO_REF:0000041, RGD:631755, RGD:13792537, RGD:12859071 NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
JBrowse link
G Nags N-acetylglutamate synthase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:90,084,607...90,089,693
Ensembl chr10:90,085,559...90,089,693
JBrowse link
arginine biosynthetic process via ornithine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asl argininosuccinate lyase IEA
IBA
GO_REF:0000002
PMID:21873635
InterPro PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr12:30,160,922...30,178,348
Ensembl chr12:30,165,694...30,178,341
JBrowse link
G Otc ornithine carbamoyltransferase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:13,524,804...13,601,074
Ensembl chr  X:13,524,607...13,601,069
JBrowse link
asparagine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asns asparagine synthetase (glutamine-hydrolyzing) IDA
IBA
ISO
PMID:21873635
(PMID:2573597)
RGD PMID:2573597, PMID:2887559, PMID:21873635 RGD:2316002, RGD:13792537 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Asnsd1 asparagine synthetase domain containing 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:52,988,042...53,009,054
Ensembl chr 9:53,004,499...53,009,054
JBrowse link
aspartate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 ISO
IBA
(MGI:MGI:53641|PMID:4193185)
PMID:21873635
RGD PMID:4193185, PMID:21873635 MGI:MGI:53641, RGD:13792537 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Got1l1 glutamic-oxaloacetic transaminase 1-like 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:69,022,756...69,035,507
Ensembl chr16:69,022,784...69,028,179
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 ISO (MGI:MGI:53641|PMID:4193185) RGD PMID:4193185 MGI:MGI:53641 NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340
JBrowse link
citrulline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 ISO (PMID:11092761), (PMID:26297558) RGD PMID:11092761, PMID:26297558 NCBI chr 1:259,641,673...259,674,521
Ensembl chr 1:259,641,676...259,674,425
Ensembl chr 1:259,641,676...259,674,425
JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:7053379, PMID:21873635 RGD:10755426, RGD:13792537 NCBI chr 6:26,657,507...26,680,459
Ensembl chr 6:26,657,780...26,680,284
JBrowse link
G Otc ornithine carbamoyltransferase IDA
IBA
ISO
PMID:21873635
(PMID:2556444), (PMID:8112735)
RGD PMID:2556444, PMID:8112735, PMID:9472964, PMID:21873635 RGD:4144071, RGD:13792537 NCBI chr  X:13,524,804...13,601,074
Ensembl chr  X:13,524,607...13,601,069
JBrowse link
cysteine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase ISO MGI:MGI:1857139 (MGI:MGI:3044255|PMID:15030387)
(PMID:24416422)
RGD PMID:15030387, PMID:24416422 MGI:MGI:3044255 NCBI chr20:10,361,987...10,386,663
Ensembl chr20:10,361,988...10,386,751
JBrowse link
G Cth cystathionine gamma-lyase IDA
IEA
ISS
ISO
GO_REF:0000041
GO_REF:0000024
(PMID:10212249)
UniProt
RGD
PMID:10212249, PMID:9359866 GO_REF:0000024, GO_REF:0000041, RGD:1359024 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 ISO (MGI:MGI:5294309|PMID:12468440) RGD PMID:12468440 MGI:MGI:5294309 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
G LOC103691744 cystathionine gamma-lyase IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 2:264,747,068...264,765,112
Ensembl chr 2:264,746,485...264,765,085
JBrowse link
cysteine biosynthetic process from serine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase TAS RGD PMID:9359866 RGD:1359024 NCBI chr20:10,361,987...10,386,663
Ensembl chr20:10,361,988...10,386,751
JBrowse link
cysteine biosynthetic process via cystathionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr20:10,361,987...10,386,663
Ensembl chr20:10,361,988...10,386,751
JBrowse link
G Cth cystathionine gamma-lyase ISO
IBA
(PMID:19428278)
PMID:21873635
RGD PMID:19428278, PMID:21873635 RGD:13792537 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
D-serine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Srr serine racemase ISO
IBA
(PMID:11054547), (PMID:15193426)
PMID:21873635
(MGI:MGI:1347751|PMID:10557334), (MGI:MGI:1926659|PMID:11054547), (MGI:MGI:2183617|PMID:12021263), (MGI:MGI:3529732|PMID:15710237)
RGD PMID:10557334, PMID:11054547, PMID:12021263, PMID:15193426, PMID:15710237, PMID:21873635 MGI:MGI:1347751, MGI:MGI:1926659, MGI:MGI:2183617, MGI:MGI:3529732, RGD:13792537 NCBI chr10:61,756,138...61,772,327
Ensembl chr10:61,756,138...61,772,293
JBrowse link
glutamate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gls glutaminase IEA
IBA
ISO
ISS
GO_REF:0000107
PMID:21873635
(PMID:16899818), (PMID:22049910)
GO_REF:0000024
(MGI:MGI:5320252|PMID:22228304)
Ensembl
RGD
UniProt
PMID:16899818, PMID:22049910, PMID:22228304, PMID:21873635 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5320252, RGD:13792537 NCBI chr 9:54,212,622...54,284,879
Ensembl chr 9:54,212,767...54,284,872
JBrowse link
G Gls2 glutaminase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:2,605,679...2,621,853
Ensembl chr 7:2,605,719...2,621,852
JBrowse link
G Glud1 glutamate dehydrogenase 1 ISO (PMID:11032875) RGD PMID:11032875 NCBI chr16:10,661,486...10,695,557
Ensembl chr16:10,662,021...10,695,557
JBrowse link
G Slc25a12 solute carrier family 25 member 12 IMP RGD PMID:19764902 RGD:13628741 NCBI chr 3:57,881,951...57,998,214
Ensembl chr 3:57,882,370...57,957,346
JBrowse link
glutamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glul glutamate-ammonia ligase IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:4403443, PMID:21873635, PMID:28323 RGD:2301548, RGD:13792537, RGD:2301547 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
G Lgsn lengsin, lens protein with glutamine synthetase domain NOT IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:37,458,603...37,490,117
Ensembl chr 9:37,462,693...37,490,108
JBrowse link
glycine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC688286 similar to threonine aldolase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:106,877,585...106,883,706
Ensembl chr10:106,878,085...106,883,423
JBrowse link
G Sardh sarcosine dehydrogenase TAS RGD PMID:9839943 RGD:634034 NCBI chr 3:5,737,203...5,802,153
Ensembl chr 3:5,737,200...5,802,129
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 IDA from L-allothreonine in the absence of tetrahydrofolate RGD PMID:3110140 RGD:2300383 NCBI chr10:47,030,813...47,059,216
Ensembl chr10:47,031,050...47,059,216
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 IDA from L-allothreonine in the absence of tetrahydrofolate RGD PMID:3110140 RGD:2300383 NCBI chr 7:70,824,718...70,829,822
Ensembl chr 7:70,824,715...70,829,815
JBrowse link
glycine biosynthetic process from serine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shmt1 serine hydroxymethyltransferase 1 IDA
IBA
in the presence of tetrahydrofolate
PMID:21873635
RGD
GO_Central
PMID:3110140, PMID:21873635 RGD:2300383, RGD:13792537 NCBI chr10:47,030,813...47,059,216
Ensembl chr10:47,031,050...47,059,216
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 IDA
IBA
in the presence of tetrahydrofolate
PMID:21873635
RGD
GO_Central
PMID:3110140, PMID:21873635 RGD:2300383, RGD:13792537 NCBI chr 7:70,824,718...70,829,822
Ensembl chr 7:70,824,715...70,829,815
JBrowse link
glycine biosynthetic process, by transamination of glyoxylate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agxt alanine--glyoxylate and serine--pyruvate aminotransferase IDA
IBA
ISO
PMID:21873635
(PMID:22198249)
RGD PMID:22198249, PMID:12383475, PMID:21873635 RGD:1599457, RGD:13792537 NCBI chr 9:100,281,339...100,291,292
Ensembl chr 9:100,281,339...100,291,291
JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 ISO (PMID:20018850) RGD PMID:20018850 NCBI chr 2:60,337,667...60,379,144
Ensembl chr 2:60,337,667...60,379,420
JBrowse link
histidine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 6:99,282,850...99,350,367
Ensembl chr 6:99,282,850...99,350,340
JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:18,640,274...18,721,298
Ensembl chr14:18,640,277...18,720,357
JBrowse link
hydroxylysine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 IEA
ISO
GO_REF:0000107
(PMID:10934207)
Ensembl
RGD
PMID:10934207 GO_REF:0000107 NCBI chr 8:99,977,334...100,059,736
Ensembl chr 8:99,977,334...100,059,736
JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 ISO (MGI:MGI:6202004|PMID:16447251) RGD PMID:16447251 MGI:MGI:6202004 NCBI chr12:22,716,421...22,726,982
Ensembl chr12:22,716,423...22,726,982
JBrowse link
isoleucine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ilvbl ilvB acetolactate synthase like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:14,044,586...14,054,639
Ensembl chr 7:14,044,586...14,054,639
JBrowse link
G Sds serine dehydratase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:41,620,429...41,627,741
Ensembl chr12:41,620,393...41,627,741
JBrowse link
G Sdsl serine dehydratase-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:41,636,994...41,647,205
Ensembl chr12:41,636,994...41,647,205
JBrowse link
L-asparagine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asns asparagine synthetase (glutamine-hydrolyzing) IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
L-methionine salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase ISO
IEA
(PMID:18230605)
GO_REF:0000107
RGD
Ensembl
PMID:18230605 GO_REF:0000107 NCBI chr 2:23,236,573...23,256,158
Ensembl chr 2:23,236,575...23,256,158
JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 ISO
IEA
(PMID:18230605)
GO_REF:0000107
RGD
Ensembl
PMID:18230605 GO_REF:0000107 NCBI chr 2:23,272,320...23,289,266
Ensembl chr 2:23,272,328...23,289,266
JBrowse link
L-methionine salvage from methylthioadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adi1 acireductone dioxygenase 1 IEA
ISS
ISO
GO_REF:0000041
GO_REF:0000024
(PMID:15938715)
UniProt
RGD
PMID:15938715 GO_REF:0000024, GO_REF:0000041 NCBI chr 6:47,940,211...47,947,173
Ensembl chr 6:47,940,183...47,947,230
JBrowse link
G Apip APAF1 interacting protein IEA
IBA
ISO
GO_REF:0000041
PMID:21873635
(PMID:22837397), (PMID:23285211)
UniProt
RGD
PMID:22837397, PMID:23285211, PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 3:92,969,128...92,998,104
Ensembl chr 3:92,969,141...92,995,483
JBrowse link
G Enoph1 enolase-phosphatase 1 IEA
IBA
ISS
ISO
GO_REF:0000041
PMID:21873635
GO_REF:0000024
(PMID:15843022)
UniProt
RGD
PMID:15843022, PMID:21873635 GO_REF:0000024, GO_REF:0000041, RGD:13792537 NCBI chr14:11,172,359...11,198,799
Ensembl chr14:11,172,362...11,198,194
JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 IEA
IBA
GO_REF:0000041
PMID:21873635
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr19:25,360,299...25,366,283
Ensembl chr19:25,360,164...25,366,806
JBrowse link
G Mtap methylthioadenosine phosphorylase IEA
IBA
GO_REF:0000041
PMID:21873635
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 5:107,711,077...107,777,530
Ensembl chr 5:107,711,077...107,777,530
JBrowse link
L-methionine salvage from S-adenosylmethionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apip APAF1 interacting protein IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:92,969,128...92,998,104
Ensembl chr 3:92,969,141...92,995,483
JBrowse link
G Enoph1 enolase-phosphatase 1 IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr14:11,172,359...11,198,799
Ensembl chr14:11,172,362...11,198,194
JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr19:25,360,299...25,366,283
Ensembl chr19:25,360,164...25,366,806
JBrowse link
L-proline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:259,641,673...259,674,521
Ensembl chr 1:259,641,676...259,674,425
Ensembl chr 1:259,641,676...259,674,425
JBrowse link
G LOC108348083 delta-1-pyrroline-5-carboxylate synthase IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:259,057,407...259,089,727
Ensembl chr 1:259,057,402...259,089,642
JBrowse link
G Noxred1 NADP-dependent oxidoreductase domain containing 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:111,243,232...111,271,107
Ensembl chr 6:111,243,228...111,267,734
JBrowse link
G Oat ornithine aminotransferase IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:204,562,289...204,582,070
Ensembl chr 1:204,562,289...204,582,070
JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 IEA
IBA
GO_REF:0000041
PMID:21873635
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr10:109,817,300...109,822,218
Ensembl chr10:109,818,177...109,821,807
JBrowse link
G Pycr2 pyrroline-5-carboxylate reductase 2 IEA
IBA
GO_REF:0000041
PMID:21873635
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr13:99,184,624...99,188,418
Ensembl chr13:99,184,564...99,188,431
JBrowse link
G Pycr3 pyrroline-5-carboxylate reductase 3 IEA
IBA
ISS
ISO
GO_REF:0000041
PMID:21873635
GO_REF:0000024
(PMID:23024808)
UniProt
RGD
PMID:23024808, PMID:21873635 GO_REF:0000024, GO_REF:0000041, RGD:13792537 NCBI chr 7:116,949,882...116,955,150
Ensembl chr 7:116,949,879...116,955,148
JBrowse link
L-serine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Phgdh phosphoglycerate dehydrogenase IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:200,484,245...200,513,564
Ensembl chr 2:200,484,246...200,513,564
JBrowse link
G Psat1 phosphoserine aminotransferase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:233,124,089...233,145,941
Ensembl chr 1:233,124,092...233,145,941
JBrowse link
G Psph phosphoserine phosphatase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:30,514,128...30,526,551
Ensembl chr12:30,514,112...30,526,557
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 IDA RGD PMID:10457370 RGD:2300380 NCBI chr 7:70,824,718...70,829,822
Ensembl chr 7:70,824,715...70,829,815
JBrowse link
leucine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcat1 branched chain amino acid transaminase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:179,259,305...179,340,021
Ensembl chr 4:179,259,308...179,339,795
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:11733007, PMID:21873635 RGD:1582175, RGD:13792537 NCBI chr 1:101,553,900...101,572,103
Ensembl chr 1:101,554,642...101,572,080
JBrowse link
lysine biosynthetic process via aminoadipic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aasdhppt aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:1,432,757...1,450,175
Ensembl chr 8:1,439,340...1,450,138
JBrowse link
G Aass aminoadipate-semialdehyde synthase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:50,152,005...50,208,935
Ensembl chr 4:50,152,452...50,200,328
JBrowse link
methionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase IDA
ISO
(MGI:MGI:3510291|PMID:15217352) RGD PMID:15217352, PMID:15845641 MGI:MGI:3510291, RGD:1359026 NCBI chr 2:23,236,573...23,256,158
Ensembl chr 2:23,236,575...23,256,158
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 ISO (PMID:25633902) RGD PMID:25633902 NCBI chr 6:99,282,850...99,350,367
Ensembl chr 6:99,282,850...99,350,340
JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:18,640,274...18,721,298
Ensembl chr14:18,640,277...18,720,357
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO
IBA
MGI:MGI:2385823 (MGI:MGI:3510291|PMID:15217352)
PMID:21873635
RGD PMID:15217352, PMID:21873635 MGI:MGI:3510291, RGD:13792537 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase IDA
IEA
ISO
GO_REF:0000107
(PMID:23825108)
MGI:MGI:2180496 (MGI:MGI:1930456|PMID:11158293)
Ensembl
RGD
PMID:11158293, PMID:23825108, PMID:15845641, PMID:11730351 GO_REF:0000107, MGI:MGI:1930456, RGD:1359026, RGD:1601423 NCBI chr17:66,210,444...66,295,014
Ensembl chr17:66,210,461...66,295,014
JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase ISO
IBA
(PMID:11466310)
PMID:21873635
(MGI:MGI:3710265|PMID:17369066)
RGD PMID:11466310, PMID:17369066, PMID:21873635 MGI:MGI:3710265, RGD:13792537 NCBI chr 1:37,743,089...37,774,485
Ensembl chr 1:37,743,147...37,774,015
JBrowse link
negative regulation of citrulline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 ISO (PMID:19278978) RGD PMID:19278978 NCBI chr13:50,091,644...50,153,808
Ensembl chr13:50,091,430...50,153,823
JBrowse link
ornithine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 ISO (PMID:11092761), (PMID:26297558) RGD PMID:11092761, PMID:26297558 NCBI chr 1:259,641,673...259,674,521
Ensembl chr 1:259,641,676...259,674,425
Ensembl chr 1:259,641,676...259,674,425
JBrowse link
positive regulation of L-dopa biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase ISO
IEA
ISS
(PMID:16731528)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
ParkinsonsUK-UCL
PMID:16731528 GO_REF:0000024, GO_REF:0000107 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
proline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 ISO (PMID:11092761), (PMID:26297558) RGD PMID:11092761, PMID:26297558 NCBI chr 1:259,641,673...259,674,521
Ensembl chr 1:259,641,676...259,674,425
Ensembl chr 1:259,641,676...259,674,425
JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 ISO (PMID:16730026) RGD PMID:16730026 NCBI chr10:109,817,300...109,822,218
Ensembl chr10:109,818,177...109,821,807
JBrowse link
G Pycr2 pyrroline-5-carboxylate reductase 2 ISO
ISS
(PMID:23024808)
GO_REF:0000024
RGD
UniProt
PMID:23024808 GO_REF:0000024 NCBI chr13:99,184,624...99,188,418
Ensembl chr13:99,184,564...99,188,431
JBrowse link
regulation of arginine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO (MGI:MGI:4830440|PMID:19284480) RGD PMID:19284480 MGI:MGI:4830440 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
selenocysteine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sephs1 selenophosphate synthetase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:77,312,562...77,340,934
Ensembl chr17:77,312,562...77,340,934
JBrowse link
G Sephs2 selenophosphate synthetase 2 ISO (MGI:MGI:3711593|PMID:17346238) RGD PMID:17346238 MGI:MGI:3711593 NCBI chr 1:198,719,158...198,721,476
Ensembl chr 1:198,719,162...198,721,476
JBrowse link
serine family amino acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 ISO (PMID:25633902) RGD PMID:25633902 NCBI chr 6:99,282,850...99,350,367
Ensembl chr 6:99,282,850...99,350,340
JBrowse link
G Phgdh phosphoglycerate dehydrogenase TAS RGD PMID:9163325 RGD:61693 NCBI chr 2:200,484,245...200,513,564
Ensembl chr 2:200,484,246...200,513,564
JBrowse link
threonine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Thnsl2 threonine synthase-like 2 NOT ISO (MGI:MGI:3690523|PMID:17034760) RGD PMID:17034760 MGI:MGI:3690523 NCBI chr 4:98,976,559...98,997,187
Ensembl chr 4:98,976,550...98,995,590
JBrowse link
tyrosine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pah phenylalanine hydroxylase IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:16953590, PMID:21873635 RGD:1601531, RGD:13792537 NCBI chr 7:28,066,639...28,129,772
Ensembl chr 7:28,066,635...28,129,769
JBrowse link
tyrosine biosynthetic process, by oxidation of phenylalanine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pah phenylalanine hydroxylase IDA RGD PMID:10839989 RGD:1601535 NCBI chr 7:28,066,639...28,129,772
Ensembl chr 7:28,066,635...28,129,769
JBrowse link
valine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcat1 branched chain amino acid transaminase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:179,259,305...179,340,021
Ensembl chr 4:179,259,308...179,339,795
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:101,553,900...101,572,103
Ensembl chr 1:101,554,642...101,572,080
JBrowse link
G Ilvbl ilvB acetolactate synthase like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:14,044,586...14,054,639
Ensembl chr 7:14,044,586...14,054,639
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      primary metabolic process 10941
        cellular amino acid metabolic process 276
          alpha-amino acid metabolic process 201
            alpha-amino acid biosynthetic process 66
              1-aminocyclopropane-1-carboxylate biosynthetic process 1
              3-cyano-L-alanine biosynthetic process 0
              4-hydroxyproline biosynthetic process 0
              D-amino acid biosynthetic process + 1
              L-dopa biosynthetic process + 1
              N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthetic process + 0
              aspartate family amino acid biosynthetic process + 22
              citrulline biosynthetic process + 4
              discadenine biosynthetic process 0
              erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process + 0
              glutamine family amino acid biosynthetic process + 18
              histidine biosynthetic process + 2
              homocysteine biosynthetic process + 0
              homomethionine biosynthetic process 0
              isoleucine biosynthetic process + 3
              leucine biosynthetic process + 2
              ornithine biosynthetic process 1
              phosphoarginine biosynthetic process 0
              pyruvate family amino acid biosynthetic process + 0
              sarcosine biosynthetic process 0
              serine family amino acid biosynthetic process + 17
              stachydrine biosynthetic process 0
              tryptophan biosynthetic process 0
              tyrosine biosynthetic process + 1
              valine biosynthetic process 3
Path 2
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      organic substance metabolic process 11660
        organic acid metabolic process 1095
          oxoacid metabolic process 1066
            carboxylic acid metabolic process 1009
              carboxylic acid biosynthetic process 318
                cellular amino acid biosynthetic process 71
                  alpha-amino acid biosynthetic process 66
                    1-aminocyclopropane-1-carboxylate biosynthetic process 1
                    3-cyano-L-alanine biosynthetic process 0
                    4-hydroxyproline biosynthetic process 0
                    D-amino acid biosynthetic process + 1
                    L-dopa biosynthetic process + 1
                    N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthetic process + 0
                    aspartate family amino acid biosynthetic process + 22
                    citrulline biosynthetic process + 4
                    discadenine biosynthetic process 0
                    erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process + 0
                    glutamine family amino acid biosynthetic process + 18
                    histidine biosynthetic process + 2
                    homocysteine biosynthetic process + 0
                    homomethionine biosynthetic process 0
                    isoleucine biosynthetic process + 3
                    leucine biosynthetic process + 2
                    ornithine biosynthetic process 1
                    phosphoarginine biosynthetic process 0
                    pyruvate family amino acid biosynthetic process + 0
                    sarcosine biosynthetic process 0
                    serine family amino acid biosynthetic process + 17
                    stachydrine biosynthetic process 0
                    tryptophan biosynthetic process 0
                    tyrosine biosynthetic process + 1
                    valine biosynthetic process 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.