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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of voltage-gated calcium channel activity
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Accession:GO:1901386 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated calcium channel activity.
Synonyms:exact_synonym: down regulation of depolarization-activated voltage gated calcium channel activity;   down regulation of depolarization-activated voltage-gated calcium channel;   down regulation of voltage gated calcium channel activity;   down regulation of voltage-dependent calcium channel activity;   down regulation of voltage-gated calcium ion channel activity;   down regulation of voltage-sensitive calcium channel;   downregulation of depolarization-activated voltage gated calcium channel activity;   downregulation of depolarization-activated voltage-gated calcium channel;   downregulation of voltage gated calcium channel activity;   downregulation of voltage-dependent calcium channel activity;   downregulation of voltage-gated calcium ion channel activity;   downregulation of voltage-sensitive calcium channel;   inhibition of depolarization-activated voltage gated calcium channel activity;   inhibition of depolarization-activated voltage-gated calcium channel;   inhibition of voltage-dependent calcium channel activity;   inhibition of voltage-gated calcium ion channel activity;   inhibition of voltage-sensitive calcium channel;   negative regulation of depolarization-activated voltage gated calcium channel activity;   negative regulation of depolarization-activated voltage-gated calcium channel;   negative regulation of voltage-dependent calcium channel activity;   negative regulation of voltage-gated calcium ion channel activity;   negative regulation of voltage-sensitive calcium channel
 narrow_synonym: down regulation of dihydropyridine-sensitive calcium channel activity;   downregulation of dihydropyridine-sensitive calcium channel activity;   inhibition of dihydropyridine-sensitive calcium channel activity;   inhibition of voltage-gated calcium channel activity;   negative regulation of dihydropyridine-sensitive calcium channel activity
 broad_synonym: down regulation of depolarization-activated calcium channel;   downregulation of depolarization-activated calcium channel;   inhibition of depolarization-activated calcium channel;   negative regulation of depolarization-activated calcium channel


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negative regulation of voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CABP1 calcium binding protein 1 ISO RGD PMID:17960496 RGD:7207144 NCBI chr14:40,563,302...40,587,975 JBrowse link
G CACNA1F calcium voltage-gated channel subunit alpha1 F involved_in ISO (PMID:27226626) UniProt PMID:27226626 NCBI chr  X:43,250,449...43,284,458
Ensembl chr  X:43,246,786...43,283,990
JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 ISO RGD PMID:15024042 RGD:13514097 NCBI chr 5:14,875,524...14,888,224
Ensembl chr 5:14,874,238...14,888,224
JBrowse link
G CBARP CACN subunit beta associated regulatory protein involved_in IBA
ISO
(PMID:21873635) GO_Central
RGD
PMID:21873635 PMID:24751537 RGD:10047103 NCBI chr 2:77,220,790...77,230,418
Ensembl chr 2:77,221,171...77,230,056
JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 involved_in ISO (PMID:18292205) UniProt PMID:18292205 NCBI chr12:17,251,361...17,306,308
Ensembl chr12:17,252,018...17,306,319
JBrowse link
G DRD2 dopamine receptor D2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:41,068,618...41,135,262
Ensembl chr 9:41,068,779...41,133,599
JBrowse link
G DRD3 dopamine receptor D3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr13:145,769,294...145,817,997
Ensembl chr13:145,771,510...145,819,173
JBrowse link
G DRD4 dopamine receptor D4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:398,766...401,539
Ensembl chr 2:398,766...401,432
JBrowse link
G FMR1 FMRP translational regulator 1 involved_in ISO PMID:24709664 UniProt PMID:24709664 RGD:11059581 NCBI chr  X:120,361,232...120,400,282
Ensembl chr  X:120,361,229...120,399,835
JBrowse link
G GNB5 G protein subunit beta 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:119,545,382...119,589,860
Ensembl chr 1:119,484,397...119,589,868
JBrowse link
G GPR35 G protein-coupled receptor 35 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:139,571,093...139,591,638
Ensembl chr15:139,571,086...139,591,632
JBrowse link
G OPRL1 opioid related nociceptin receptor 1 ISO RGD PMID:15937148 RGD:9835002 NCBI chr17:62,905,700...62,913,018
Ensembl chr17:62,897,727...62,913,754
JBrowse link
negative regulation of high voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALM1 calmodulin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:112,160,823...112,171,754
Ensembl chr 7:112,154,880...112,171,744
JBrowse link
G CALM2 calmodulin 2 involved_in ISO (PMID:31454269) UniProt PMID:31454269 NCBI chr 3:93,371,765...93,386,378
Ensembl chr 3:93,372,045...93,438,068
JBrowse link
G CALM3 calmodulin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:52,506,979...52,516,704
Ensembl chr 6:52,506,674...52,516,703
JBrowse link
G DYSF dysferlin acts_upstream_of_or_within ISO (MGI:5545678|PMID:24302765) MGI PMID:24302765 MGI:5545678 NCBI chr 3:71,020,143...71,237,658
Ensembl chr 3:71,020,141...71,246,967
JBrowse link
G GEM GTP binding protein overexpressed in skeletal muscle involved_in IEA UniProt GO_REF:0000104 NCBI chr 4:42,458,591...42,471,941
Ensembl chr 4:42,249,479...42,471,937
JBrowse link
G REM1 RRAD and GEM like GTPase 1 involved_in IEA UniProt GO_REF:0000104 NCBI chr17:35,208,344...35,218,771
Ensembl chr17:35,208,363...35,218,768
JBrowse link
G RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator involved_in IEA UniProt GO_REF:0000104 NCBI chr 6:27,601,692...27,605,127
Ensembl chr 6:27,601,692...27,605,083
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16574
    negative regulation of biological process 5320
      negative regulation of transport 512
        negative regulation of transporter activity 86
          negative regulation of ion transmembrane transporter activity 77
            negative regulation of calcium ion transmembrane transporter activity 36
              negative regulation of voltage-gated calcium channel activity 19
                negative regulation of high voltage-gated calcium channel activity 7
Path 2
Term Annotations click to browse term
  biological_process 16574
    localization 5969
      establishment of localization 4443
        transport 4279
          ion transport 1544
            cation transport 1168
              metal ion transport 869
                calcium ion transport 436
                  regulation of calcium ion transport 290
                    regulation of calcium ion transmembrane transport 176
                      regulation of calcium ion transmembrane transporter activity 90
                        negative regulation of calcium ion transmembrane transporter activity 36
                          negative regulation of voltage-gated calcium channel activity 19
                            negative regulation of high voltage-gated calcium channel activity 7
paths to the root