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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of voltage-gated calcium channel activity
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Accession:GO:1901386 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated calcium channel activity.
Synonyms:exact_synonym: down regulation of depolarization-activated voltage gated calcium channel activity;   down regulation of depolarization-activated voltage-gated calcium channel;   down regulation of voltage gated calcium channel activity;   down regulation of voltage-dependent calcium channel activity;   down regulation of voltage-gated calcium ion channel activity;   down regulation of voltage-sensitive calcium channel;   downregulation of depolarization-activated voltage gated calcium channel activity;   downregulation of depolarization-activated voltage-gated calcium channel;   downregulation of voltage gated calcium channel activity;   downregulation of voltage-dependent calcium channel activity;   downregulation of voltage-gated calcium ion channel activity;   downregulation of voltage-sensitive calcium channel;   inhibition of depolarization-activated voltage gated calcium channel activity;   inhibition of depolarization-activated voltage-gated calcium channel;   inhibition of voltage-dependent calcium channel activity;   inhibition of voltage-gated calcium ion channel activity;   inhibition of voltage-sensitive calcium channel;   negative regulation of depolarization-activated voltage gated calcium channel activity;   negative regulation of depolarization-activated voltage-gated calcium channel;   negative regulation of voltage-dependent calcium channel activity;   negative regulation of voltage-gated calcium ion channel activity;   negative regulation of voltage-sensitive calcium channel
 narrow_synonym: down regulation of dihydropyridine-sensitive calcium channel activity;   downregulation of dihydropyridine-sensitive calcium channel activity;   inhibition of dihydropyridine-sensitive calcium channel activity;   inhibition of voltage-gated calcium channel activity;   negative regulation of dihydropyridine-sensitive calcium channel activity
 broad_synonym: down regulation of depolarization-activated calcium channel;   downregulation of depolarization-activated calcium channel;   inhibition of depolarization-activated calcium channel;   negative regulation of depolarization-activated calcium channel


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negative regulation of voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CABP1 calcium binding protein 1 ISO RGD PMID:17960496 RGD:7207144 NCBI chr12:120,640,552...120,680,869
Ensembl chr12:120,640,552...120,667,324
JBrowse link
G CACNA1F calcium voltage-gated channel subunit alpha1 F involved_in IDA (PMID:27226626) UniProt PMID:27226626 NCBI chr  X:49,205,063...49,233,404
Ensembl chr  X:49,205,063...49,233,371
JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 involved_in IEA
ISO
Ensembl
RGD
PMID:15024042 GO_REF:0000107 RGD:13514097 NCBI chr12:48,814,432...48,828,941
Ensembl chr12:48,813,794...48,828,941
JBrowse link
G CBARP CACN subunit beta associated regulatory protein involved_in IBA
ISO
IEA
ISS
(PMID:21873635) GO_Central
RGD
InterPro
UniProt
PMID:21873635 PMID:24751537 GO_REF:0000002 GO_REF:0000024 RGD:10047103 NCBI chr19:1,228,287...1,238,512
Ensembl chr19:1,228,287...1,238,027
JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 involved_in IDA (PMID:18292205) UniProt PMID:18292205 NCBI chr17:45,784,320...45,835,828
Ensembl chr17:45,784,280...45,835,828
JBrowse link
G DRD2 dopamine receptor D2 involved_in IBA
IDA
(PMID:21873635)
(PMID:7921596)
GO_Central
BHF-UCL
PMID:7921596 PMID:21873635 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
JBrowse link
G DRD3 dopamine receptor D3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407
JBrowse link
G DRD4 dopamine receptor D4 involved_in IDA (PMID:7921596) BHF-UCL PMID:7921596 NCBI chr11:637,269...640,706
Ensembl chr11:637,269...640,706
JBrowse link
G FMR1 FMRP translational regulator 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr  X:147,911,919...147,951,125
Ensembl chr  X:147,911,919...147,951,125
JBrowse link
G GNB5 G protein subunit beta 5 involved_in IDA (PMID:11007869), (PMID:12606627) UniProt PMID:11007869 PMID:12606627 NCBI chr15:52,115,100...52,191,392
Ensembl chr15:52,115,100...52,191,392
JBrowse link
G GPR35 G protein-coupled receptor 35 involved_in IMP (PMID:17940199) UniProt PMID:17940199 NCBI chr 2:240,605,430...240,633,159
Ensembl chr 2:240,605,430...240,631,259
JBrowse link
G LINC02210-CRHR1 LINC02210-CRHR1 readthrough involved_in IDA (PMID:18292205) UniProt PMID:18292205 NCBI chr17:45,620,346...45,835,828
Ensembl chr17:45,784,280...45,835,828
Ensembl chr17:45,784,280...45,835,828
JBrowse link
G OPRL1 opioid related nociceptin receptor 1 involved_in IEA
ISO
Ensembl
RGD
PMID:15937148 GO_REF:0000107 RGD:9835002 NCBI chr20:64,080,082...64,100,643
Ensembl chr20:64,080,082...64,100,643
JBrowse link
negative regulation of high voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALM1 calmodulin 1 involved_in IMP (PMID:31454269) UniProt PMID:31454269 NCBI chr14:90,396,502...90,408,268
Ensembl chr14:90,396,502...90,408,268
JBrowse link
G CALM2 calmodulin 2 involved_in IMP (PMID:31454269) UniProt PMID:31454269 NCBI chr 2:47,160,082...47,176,936
Ensembl chr 2:47,160,083...47,176,921
JBrowse link
G CALM3 calmodulin 3 involved_in IMP (PMID:31454269) UniProt PMID:31454269 NCBI chr19:46,601,074...46,610,782
Ensembl chr19:46,601,074...46,610,782
JBrowse link
G DYSF dysferlin acts_upstream_of_or_within ISO (MGI:5545678|PMID:24302765) MGI PMID:24302765 MGI:5545678 NCBI chr 2:71,453,154...71,686,763
Ensembl chr 2:71,453,561...71,686,763
JBrowse link
G GEM GTP binding protein overexpressed in skeletal muscle involved_in IEA InterPro GO_REF:0000002 NCBI chr 8:94,249,249...94,262,345
Ensembl chr 8:94,249,253...94,262,350
JBrowse link
G REM1 RRAD and GEM like GTPase 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr20:31,475,273...31,484,895
Ensembl chr20:31,475,288...31,484,895
JBrowse link
G RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator involved_in IEA InterPro GO_REF:0000002 NCBI chr16:66,921,685...66,925,535
Ensembl chr16:66,921,679...66,925,536
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18534
    negative regulation of biological process 5939
      negative regulation of transport 545
        negative regulation of transporter activity 98
          negative regulation of ion transmembrane transporter activity 89
            negative regulation of calcium ion transmembrane transporter activity 41
              negative regulation of voltage-gated calcium channel activity 20
                negative regulation of high voltage-gated calcium channel activity 7
Path 2
Term Annotations click to browse term
  biological_process 18534
    localization 6635
      establishment of localization 5028
        transport 4866
          ion transport 1694
            cation transport 1291
              metal ion transport 962
                calcium ion transport 480
                  regulation of calcium ion transport 315
                    regulation of calcium ion transmembrane transport 191
                      regulation of calcium ion transmembrane transporter activity 101
                        negative regulation of calcium ion transmembrane transporter activity 41
                          negative regulation of voltage-gated calcium channel activity 20
                            negative regulation of high voltage-gated calcium channel activity 7
paths to the root