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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of voltage-gated calcium channel activity
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Accession:GO:1901386 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated calcium channel activity.
Synonyms:exact_synonym: down regulation of depolarization-activated voltage gated calcium channel activity;   down regulation of depolarization-activated voltage-gated calcium channel;   down regulation of voltage gated calcium channel activity;   down regulation of voltage-dependent calcium channel activity;   down regulation of voltage-gated calcium ion channel activity;   down regulation of voltage-sensitive calcium channel;   downregulation of depolarization-activated voltage gated calcium channel activity;   downregulation of depolarization-activated voltage-gated calcium channel;   downregulation of voltage gated calcium channel activity;   downregulation of voltage-dependent calcium channel activity;   downregulation of voltage-gated calcium ion channel activity;   downregulation of voltage-sensitive calcium channel;   inhibition of depolarization-activated voltage gated calcium channel activity;   inhibition of depolarization-activated voltage-gated calcium channel;   inhibition of voltage-dependent calcium channel activity;   inhibition of voltage-gated calcium ion channel activity;   inhibition of voltage-sensitive calcium channel;   negative regulation of depolarization-activated voltage gated calcium channel activity;   negative regulation of depolarization-activated voltage-gated calcium channel;   negative regulation of voltage-dependent calcium channel activity;   negative regulation of voltage-gated calcium ion channel activity;   negative regulation of voltage-sensitive calcium channel
 narrow_synonym: down regulation of dihydropyridine-sensitive calcium channel activity;   downregulation of dihydropyridine-sensitive calcium channel activity;   inhibition of dihydropyridine-sensitive calcium channel activity;   inhibition of voltage-gated calcium channel activity;   negative regulation of dihydropyridine-sensitive calcium channel activity
 broad_synonym: down regulation of depolarization-activated calcium channel;   downregulation of depolarization-activated calcium channel;   inhibition of depolarization-activated calcium channel;   negative regulation of depolarization-activated calcium channel


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negative regulation of voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CABP1 calcium binding protein 1 ISO RGD PMID:17960496 RGD:7207144 NCBI chr26:16,492,484...16,523,265 JBrowse link
G CACNA1F calcium voltage-gated channel subunit alpha1 F involved_in ISO (PMID:27226626) UniProt PMID:27226626 NCBI chr  X:42,302,971...42,327,787
Ensembl chr  X:42,303,158...42,326,774
JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 ISO RGD PMID:15024042 RGD:13514097 NCBI chr27:5,705,587...5,714,620
Ensembl chr27:5,706,064...5,717,647
JBrowse link
G CBARP CACN subunit beta associated regulatory protein involved_in ISO (MGI:5607190|PMID:24751537) RGD
UniProt
PMID:24751537 MGI:5607190 RGD:10047103 NCBI chr20:57,554,162...57,559,126
Ensembl chr20:57,554,032...57,559,612
JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 involved_in ISO (PMID:18292205) UniProt PMID:18292205 NCBI chr 9:9,708,696...9,763,281
Ensembl chr 9:9,714,204...9,763,402
JBrowse link
G DRD2 dopamine receptor D2 involved_in ISO (PMID:7921596)
PMID:2162345
BHF-UCL PMID:2162345 PMID:7921596 RGD:8554169 NCBI chr 5:19,732,842...19,795,241
Ensembl chr 5:19,732,836...19,795,241
JBrowse link
G DRD4 dopamine receptor D4 involved_in ISO (PMID:7921596) BHF-UCL PMID:7921596
G FMR1 FMRP translational regulator 1 involved_in ISO PMID:24709664 UniProt PMID:24709664 RGD:11059581 NCBI chr  X:116,249,079...116,287,008
Ensembl chr  X:116,249,142...116,321,439
JBrowse link
G GNB5 G protein subunit beta 5 involved_in ISO (PMID:11007869), (PMID:12606627) UniProt PMID:11007869 PMID:12606627 NCBI chr30:17,835,051...17,876,443
Ensembl chr30:17,837,220...17,881,036
JBrowse link
G GPR35 G protein-coupled receptor 35 involved_in ISO (PMID:17940199) UniProt PMID:17940199 NCBI chr25:50,566,263...50,841,473 JBrowse link
G OPRL1 opioid related nociceptin receptor 1 ISO RGD PMID:15937148 RGD:9835002 NCBI chr24:47,530,039...47,537,477
Ensembl chr24:47,508,136...47,537,250
JBrowse link
negative regulation of high voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALM1 calmodulin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:61,398,231...61,408,874
Ensembl chr 8:61,398,244...61,406,195
JBrowse link
G CALM2 calmodulin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:49,299,698...49,314,533
Ensembl chr10:49,299,897...49,314,457
JBrowse link
G CALM3 calmodulin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:109,284,729...109,294,491
Ensembl chr 1:109,286,155...109,294,391
JBrowse link
G DYSF dysferlin acts_upstream_of_or_within ISO (MGI:5545678|PMID:24302765) MGI PMID:24302765 MGI:5545678 NCBI chr17:51,011,197...51,228,969
Ensembl chr17:51,011,197...51,228,876
JBrowse link
G GEM GTP binding protein overexpressed in skeletal muscle involved_in IEA UniProt GO_REF:0000104 NCBI chr29:39,016,543...39,037,761
Ensembl chr29:39,025,483...39,037,403
JBrowse link
G RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator involved_in IEA UniProt GO_REF:0000104 NCBI chr 5:82,392,608...82,395,574
Ensembl chr 5:82,392,557...82,395,561
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13872
    negative regulation of biological process 5056
      negative regulation of transport 503
        negative regulation of transporter activity 82
          negative regulation of ion transmembrane transporter activity 73
            negative regulation of calcium ion transmembrane transporter activity 34
              negative regulation of voltage-gated calcium channel activity 17
                negative regulation of high voltage-gated calcium channel activity 6
Path 2
Term Annotations click to browse term
  biological_process 13872
    localization 5406
      establishment of localization 3937
        transport 3774
          ion transport 1359
            cation transport 1042
              metal ion transport 772
                calcium ion transport 407
                  regulation of calcium ion transport 285
                    regulation of calcium ion transmembrane transport 172
                      regulation of calcium ion transmembrane transporter activity 86
                        negative regulation of calcium ion transmembrane transporter activity 34
                          negative regulation of voltage-gated calcium channel activity 17
                            negative regulation of high voltage-gated calcium channel activity 6
paths to the root