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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of voltage-gated calcium channel activity
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Accession:GO:1901386 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated calcium channel activity.
Synonyms:exact_synonym: down regulation of depolarization-activated voltage gated calcium channel activity;   down regulation of depolarization-activated voltage-gated calcium channel;   down regulation of voltage gated calcium channel activity;   down regulation of voltage-dependent calcium channel activity;   down regulation of voltage-gated calcium ion channel activity;   down regulation of voltage-sensitive calcium channel;   downregulation of depolarization-activated voltage gated calcium channel activity;   downregulation of depolarization-activated voltage-gated calcium channel;   downregulation of voltage gated calcium channel activity;   downregulation of voltage-dependent calcium channel activity;   downregulation of voltage-gated calcium ion channel activity;   downregulation of voltage-sensitive calcium channel;   inhibition of depolarization-activated voltage gated calcium channel activity;   inhibition of depolarization-activated voltage-gated calcium channel;   inhibition of voltage-dependent calcium channel activity;   inhibition of voltage-gated calcium ion channel activity;   inhibition of voltage-sensitive calcium channel;   negative regulation of depolarization-activated voltage gated calcium channel activity;   negative regulation of depolarization-activated voltage-gated calcium channel;   negative regulation of voltage-dependent calcium channel activity;   negative regulation of voltage-gated calcium ion channel activity;   negative regulation of voltage-sensitive calcium channel
 narrow_synonym: down regulation of dihydropyridine-sensitive calcium channel activity;   downregulation of dihydropyridine-sensitive calcium channel activity;   inhibition of dihydropyridine-sensitive calcium channel activity;   inhibition of voltage-gated calcium channel activity;   negative regulation of dihydropyridine-sensitive calcium channel activity
 broad_synonym: down regulation of depolarization-activated calcium channel;   downregulation of depolarization-activated calcium channel;   inhibition of depolarization-activated calcium channel;   negative regulation of depolarization-activated calcium channel


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negative regulation of voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CABP1 calcium binding protein 1 ISO RGD PMID:17960496 RGD:7207144 NCBI chr12:118,224,046...118,250,696 JBrowse link
G CACNA1F calcium voltage-gated channel subunit alpha1 F involved_in ISO (PMID:27226626) UniProt PMID:27226626 NCBI chr  X:41,504,804...41,533,501
Ensembl chr  X:49,356,994...49,385,678
JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 ISO RGD PMID:15024042 RGD:13514097 NCBI chr12:39,918,022...39,931,386
Ensembl chr12:40,797,293...40,811,409
JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 involved_in ISO (PMID:18292205) UniProt PMID:18292205 NCBI chr17:11,261,435...11,313,630
Ensembl chr17:11,650,057...11,701,208
JBrowse link
G DRD2 dopamine receptor D2 involved_in ISO PMID:2162345
(PMID:7921596)
BHF-UCL PMID:2162345 PMID:7921596 RGD:8554169 NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935
JBrowse link
G DRD4 dopamine receptor D4 involved_in ISO (PMID:7921596) BHF-UCL PMID:7921596 NCBI chr11:640,401...646,775 JBrowse link
G FMR1 FMRP translational regulator 1 involved_in ISO PMID:24709664 UniProt PMID:24709664 RGD:11059581 NCBI chr  X:136,937,889...136,976,828
Ensembl chr  X:147,365,748...147,405,321
JBrowse link
G GNB5 G protein subunit beta 5 involved_in ISO (PMID:11007869), (PMID:12606627) UniProt PMID:11007869 PMID:12606627 NCBI chr15:31,061,310...31,122,427
Ensembl chr15:49,388,026...49,452,123
JBrowse link
G GPR35 G protein-coupled receptor 35 involved_in ISO (PMID:17940199) UniProt PMID:17940199 NCBI chr2B:127,853,660...127,887,204
Ensembl chr2B:246,680,998...246,692,090
JBrowse link
G LOC100989336 CACN subunit beta associated regulatory protein involved_in ISO (MGI:5607190|PMID:24751537) RGD
UniProt
PMID:24751537 MGI:5607190 RGD:10047103 Ensembl chr19:1,212,854...1,220,104 JBrowse link
G OPRL1 opioid related nociceptin receptor 1 ISO RGD PMID:15937148 RGD:9835002 Ensembl chr20:62,004,176...62,017,866 JBrowse link
negative regulation of high voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALM1 calmodulin 1 involved_in ISO (PMID:31454269) UniProt PMID:31454269 NCBI chr14:71,015,099...71,026,322
Ensembl chr19:52,121,687...52,131,135
JBrowse link
G CALM2 calmodulin 2 involved_in ISO (PMID:31454269) UniProt PMID:31454269 NCBI chr2A:47,274,722...47,290,861
Ensembl chr2A:48,204,518...48,220,697
JBrowse link
G CALM3 calmodulin 3 involved_in ISO (PMID:31454269) UniProt PMID:31454269 NCBI chr19:43,593,069...43,602,550
Ensembl chr19:52,121,687...52,131,135
JBrowse link
G DYSF dysferlin acts_upstream_of_or_within ISO (MGI:5545678|PMID:24302765) MGI PMID:24302765 MGI:5545678 NCBI chr2A:71,495,573...71,730,073
Ensembl chr2A:72,994,888...73,228,846
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12652
    negative regulation of biological process 4831
      negative regulation of transport 504
        negative regulation of transporter activity 80
          negative regulation of ion transmembrane transporter activity 71
            negative regulation of calcium ion transmembrane transporter activity 33
              negative regulation of voltage-gated calcium channel activity 15
                negative regulation of high voltage-gated calcium channel activity 4
Path 2
Term Annotations click to browse term
  biological_process 12652
    localization 5012
      establishment of localization 3572
        transport 3406
          ion transport 1218
            cation transport 936
              metal ion transport 709
                calcium ion transport 396
                  regulation of calcium ion transport 284
                    regulation of calcium ion transmembrane transport 174
                      regulation of calcium ion transmembrane transporter activity 85
                        negative regulation of calcium ion transmembrane transporter activity 33
                          negative regulation of voltage-gated calcium channel activity 15
                            negative regulation of high voltage-gated calcium channel activity 4
paths to the root