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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of voltage-gated calcium channel activity
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Accession:GO:1901385 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of voltage-gated calcium channel activity.
Synonyms:exact_synonym: regulation of depolarization-activated voltage gated calcium channel activity;   regulation of depolarization-activated voltage-gated calcium channel;   regulation of voltage-dependent calcium channel activity;   regulation of voltage-gated calcium ion channel activity;   regulation of voltage-sensitive calcium channel
 narrow_synonym: regulation of dihydropyridine-sensitive calcium channel activity
 broad_synonym: regulation of depolarization-activated calcium channel


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regulation of voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahnak AHNAK nucleoprotein involved_in ISO (PMID:22038483) RGD PMID:22038483 NCBI chr 1:205,882,223...205,970,934 JBrowse link
G Cabp1 calcium binding protein 1 IDA RGD PMID:17224447 RGD:7207146 NCBI chr12:41,385,234...41,448,930 JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A IMP RGD PMID:17196942 RGD:1598976 NCBI chr19:23,520,741...23,819,971 JBrowse link
G Cacnb1 calcium voltage-gated channel auxiliary subunit beta 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:82,998,182...83,018,838 JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:12042350, PMID:21873635 RGD:632406, RGD:13792537 NCBI chr17:77,564,630...77,910,000 JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:129,784,799...129,797,074 JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 involved_in ISO
IBA
(PMID:11880487)
PMID:21873635
RGD PMID:11880487, PMID:21873635 RGD:13792537 NCBI chr 3:36,906,771...37,169,191 JBrowse link
G Dmd dystrophin involved_in ISO (MGI:5487517|PMID:21677768) RGD PMID:21677768 MGI:5487517 NCBI chr  X:47,272,324...49,504,219 JBrowse link
G Hpca hippocalcin involved_in ISS
ISO
GO_REF:0000024
(PMID:28398555)
UniProt
RGD
PMID:28398555 GO_REF:0000024 NCBI chr 5:141,455,616...141,466,252 JBrowse link
G Stac SH3 and cysteine rich domain acts_upstream_of_or_within ISO MGI:4365152 (MGI:5643852|PMID:23818578) RGD PMID:23818578 MGI:5643852 NCBI chr 8:111,530,800...111,653,228 JBrowse link
negative regulation of high voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calm1 calmodulin 1 involved_in ISO
ISS
(PMID:31454269)
GO_REF:0000024
RGD
UniProt
PMID:31454269 GO_REF:0000024 NCBI chr 6:119,487,691...119,495,759 JBrowse link
G Calm2 calmodulin 2 involved_in ISO
ISS
(PMID:31454269)
GO_REF:0000024
RGD
UniProt
PMID:31454269 GO_REF:0000024 NCBI chr 6:7,091,624...7,104,284 JBrowse link
G Calm3 calmodulin 3 involved_in ISO
ISS
(PMID:31454269)
GO_REF:0000024
RGD
UniProt
PMID:31454269 GO_REF:0000024 NCBI chr 1:77,590,668...77,597,776 JBrowse link
G Dysf dysferlin acts_upstream_of_or_within ISO MGI:3055150 (MGI:5545678|PMID:24302765) RGD PMID:24302765 MGI:5545678 NCBI chr 4:116,490,877...116,690,709 JBrowse link
G Rem1 RRAD and GEM like GTPase 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:141,103,722...141,112,206 JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator involved_in IEA GO_REF:0000104
GO_REF:0000002
UniProt
InterPro
GO_REF:0000002 GO_REF:0000104 NCBI chr19:354,184...357,424 JBrowse link
negative regulation of voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cabp1 calcium binding protein 1 IDA RGD PMID:17960496 RGD:7207144 NCBI chr12:41,385,234...41,448,930 JBrowse link
G Cacna1f calcium voltage-gated channel subunit alpha1 F involved_in ISO (PMID:27226626) RGD PMID:27226626 NCBI chr  X:14,868,096...14,896,413 JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 IDA RGD PMID:15024042 RGD:13514097 NCBI chr 7:129,784,799...129,797,074 JBrowse link
G Cbarp CACN subunit beta associated regulatory protein involved_in IMP
ISO
IBA
(MGI:5607190|PMID:24751537)
PMID:21873635
RGD PMID:24751537, PMID:24751537, PMID:21873635 MGI:5607190, RGD:10047103, RGD:13792537 NCBI chr 7:9,566,637...9,575,204 JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 involved_in ISO (PMID:18292205) RGD PMID:18292205 NCBI chr10:89,040,203...89,083,481 JBrowse link
G Drd2 dopamine receptor D2 involved_in IDA
IBA
ISO
PMID:2162345
PMID:21873635
(PMID:7921596)
RGD PMID:7921596, PMID:2162345, PMID:21873635 RGD:8554169, RGD:13792537 NCBI chr 8:49,708,903...49,772,888 JBrowse link
G Drd3 dopamine receptor D3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:56,879,689...56,931,901 JBrowse link
G Drd4 dopamine receptor D4 involved_in ISO
IEA
(PMID:7921596)
GO_REF:0000107
RGD
Ensembl
PMID:7921596 GO_REF:0000107 NCBI chr 1:196,396,366...196,400,824 JBrowse link
G Fmr1 FMRP translational regulator 1 involved_in IMP PMID:24709664 UniProt PMID:24709664 RGD:11059581 NCBI chr  X:147,240,239...147,278,057 JBrowse link
G Gnb5 G protein subunit beta 5 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:11007869), (PMID:12606627)
CAFA
Ensembl
RGD
PMID:11007869 PMID:12606627 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:76,076,227...76,104,151 JBrowse link
G Gpr35 G protein-coupled receptor 35 involved_in ISO (PMID:17940199) RGD PMID:17940199 NCBI chr 9:93,526,691...93,539,302 JBrowse link
G Oprl1 opioid related nociceptin receptor 1 IMP RGD PMID:15937148 RGD:9835002 NCBI chr 3:168,831,934...168,839,920 JBrowse link
positive regulation of high voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 involved_in IDA PMID:25527503 BHF-UCL PMID:25527503 RGD:11059598 NCBI chr 4:18,950,611...19,374,969 JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 involved_in IDA PMID:25533460 BHF-UCL PMID:25533460 RGD:11059570 NCBI chr17:77,564,630...77,910,000 JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 involved_in IMP PMID:10666413 RGD
UniProt
PMID:22187436, PMID:10666413 RGD:13514092, RGD:13673808 NCBI chr 7:129,784,799...129,797,074 JBrowse link
G Fgf14 fibroblast growth factor 14 acts_upstream_of_or_within ISO
IMP
(MGI:5510622|PMID:23831029) RGD PMID:23831029, PMID:23831029 MGI:5510622, RGD:10047342 NCBI chr15:101,045,038...101,679,888 JBrowse link
G Nipsnap2 nipsnap homolog 2 involved_in ISO (MGI:5897549|PMID:22627147) RGD PMID:22627147 MGI:5897549 NCBI chr12:26,906,068...26,944,238 JBrowse link
positive regulation of voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 IDA RGD PMID:20478999 RGD:13514093 NCBI chr 4:18,950,611...19,374,969 JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 IDA RGD PMID:15024042 RGD:13514097 NCBI chr 7:129,784,799...129,797,074 JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 IDA RGD PMID:12821675 RGD:737839 NCBI chr 3:36,906,771...37,169,191 JBrowse link
G Cdk5 cyclin-dependent kinase 5 involved_in IMP PMID:23699505 ARUK-UCL PMID:23699505 RGD:13792535 NCBI chr 4:10,754,682...10,760,110 JBrowse link
G Ehd3 EH-domain containing 3 involved_in IEA
ISO
GO_REF:0000107
(MGI:5770033|PMID:25825486)
Ensembl
RGD
PMID:25825486 GO_REF:0000107 MGI:5770033 NCBI chr 6:21,640,861...21,665,601 JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 IDA RGD PMID:14679187 RGD:7243967 NCBI chr11:31,580,951...31,594,116 JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 IDA RGD PMID:14679187 RGD:7243967 NCBI chr11:31,517,176...31,530,026 JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 IDA RGD PMID:14679187 RGD:7243967 NCBI chr 1:154,523,903...154,530,865 JBrowse link
G S100a1 S100 calcium binding protein A1 IDA RGD PMID:19657060 RGD:7205633 NCBI chr 2:175,993,922...175,998,765 JBrowse link
G Stac SH3 and cysteine rich domain involved_in IBA
ISO
PMID:21873635
(MGI:6159321|PMID:29467163)
RGD PMID:29467163, PMID:21873635 MGI:6159321, RGD:13792537 NCBI chr 8:111,530,800...111,653,228 JBrowse link
G Stac2 SH3 and cysteine rich domain 2 involved_in IBA
ISO
PMID:21873635
(MGI:6159321|PMID:29467163)
RGD PMID:29467163, PMID:21873635 MGI:6159321, RGD:13792537 NCBI chr10:83,032,417...83,048,260 JBrowse link
G Stac3 SH3 and cysteine rich domain 3 involved_in IBA
ISO
PMID:21873635
(MGI:5819142|PMID:27621462), (MGI:6159321|PMID:29467163)
RGD PMID:27621462 PMID:29467163, PMID:21873635 MGI:5819142 MGI:6159321, RGD:13792537 NCBI chr 7:63,343,078...63,350,590 JBrowse link
regulation of high voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calm1 calmodulin 1 IMP RGD PMID:18322004 RGD:7207845 NCBI chr 6:119,487,691...119,495,759 JBrowse link
G Calm2 calmodulin 2 IMP RGD PMID:18322004 RGD:7207845 NCBI chr 6:7,091,624...7,104,284 JBrowse link
G Calm3 calmodulin 3 IMP RGD PMID:18322004 RGD:7207845 NCBI chr 1:77,590,668...77,597,776 JBrowse link
G Nos1ap nitric oxide synthase 1 adaptor protein involved_in IDA PMID:24665357 BHF-UCL PMID:24665357 RGD:10047296 NCBI chr13:82,549,786...82,820,949 JBrowse link
G Nppa natriuretic peptide A involved_in IDA PMID:8301666 BHF-UCL PMID:8301666 RGD:10047161 NCBI chr 5:158,429,042...158,430,351 JBrowse link
G Pde4b phosphodiesterase 4B involved_in IEA
ISO
GO_REF:0000107
(MGI:5286798|PMID:21670503)
Ensembl
RGD
PMID:21670503 GO_REF:0000107 MGI:5286798 NCBI chr 5:116,799,827...117,367,707 JBrowse link
G Sri sorcin involved_in ISO (PMID:12754254) RGD PMID:12754254 NCBI chr 4:25,973,493...25,997,879 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of molecular function 3070
        regulation of transporter activity 303
          regulation of transmembrane transporter activity 289
            regulation of ion transmembrane transporter activity 278
              regulation of calcium ion transmembrane transporter activity 93
                regulation of voltage-gated calcium channel activity 41
                  negative regulation of voltage-gated calcium channel activity + 18
                  positive regulation of voltage-gated calcium channel activity + 15
                  regulation of high voltage-gated calcium channel activity + 15
                  regulation of light-activated voltage-gated calcium channel activity 0
Path 2
Term Annotations click to browse term
  biological_process 19492
    localization 6444
      establishment of localization 4863
        transport 4699
          ion transport 1638
            cation transport 1259
              metal ion transport 942
                calcium ion transport 456
                  regulation of calcium ion transport 297
                    regulation of calcium ion transmembrane transport 181
                      regulation of calcium ion transmembrane transporter activity 93
                        regulation of voltage-gated calcium channel activity 41
                          negative regulation of voltage-gated calcium channel activity + 18
                          positive regulation of voltage-gated calcium channel activity + 15
                          regulation of high voltage-gated calcium channel activity + 15
                          regulation of light-activated voltage-gated calcium channel activity 0
paths to the root