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ONTOLOGY REPORT - ANNOTATIONS


Term:insulin metabolic process
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Accession:GO:1901142 term browser browse the term
Definition:The chemical reactions and pathways involving insulin.
Synonyms:exact_synonym: insulin metabolism
 never_in_taxon: NCBITaxon:2 ! Fungi or Bacteria or Archaea;   NCBITaxon:2157 ! Fungi or Bacteria or Archaea;   NCBITaxon:33090 ! Viridiplantae;   NCBITaxon:4751 ! Fungi or Bacteria or Archaea



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insulin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ern1 endoplasmic reticulum to nucleus signaling 1 involved_in ISO (PMID:20103773) RGD PMID:20103773 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Ide insulin degrading enzyme involved_in ISO (PMID:18448515) RGD PMID:18448515 NCBI chr 1:235,002,984...235,102,448
Ensembl chr 1:234,995,351...235,102,440
JBrowse link
G Nlgn2 neuroligin 2 IDA RGD PMID:22528485 RGD:9743981 NCBI chr10:54,544,588...54,557,854
Ensembl chr10:54,544,588...54,558,434
JBrowse link
G Nucb2 nucleobindin 2 IDA RGD PMID:21828181 RGD:9831189 NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353
JBrowse link
G Pax6 paired box 6 IMP RGD PMID:21069736 RGD:8552358 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014
JBrowse link
G Tcf7l2 transcription factor 7 like 2 acts_upstream_of_or_within ISO MGI:1926344 (MGI:5468191|PMID:23260145) RGD PMID:23260145 MGI:5468191 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967
JBrowse link
insulin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in IMP
ISS
ISO
PMID:11850617
GO_REF:0000024
(MGI:3819735|PMID:18544705)
UniProt
RGD
PMID:18544705 PMID:11850617 GO_REF:0000024 MGI:3819735, RGD:734645 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Cela2a chymotrypsin like elastase 2A involved_in ISO
ISS
(PMID:31358993)
GO_REF:0000024
RGD
UniProt
PMID:31358993 GO_REF:0000024 NCBI chr 5:154,126,879...154,136,630
Ensembl chr 5:154,126,878...154,136,632
JBrowse link
G Ctsd cathepsin D involved_in ISO
IEA
(MGI:5812606|PMID:27703010)
GO_REF:0000107
RGD
Ensembl
PMID:27703010 GO_REF:0000107 MGI:5812606 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Ide insulin degrading enzyme involved_in ISS
ISO
GO_REF:0000024
(PMID:19321446), (PMID:9231799), (PMID:9830016)
(MGI:5583899|PMID:24847884)
(MGI:5583899|PMID:24847884), (MGI:5812606|PMID:27703010)
UniProt
RGD
PMID:9231799 PMID:9830016 PMID:19321446 PMID:24847884 PMID:27703010 GO_REF:0000024 MGI:5583899 MGI:5812606 NCBI chr 1:235,002,984...235,102,448
Ensembl chr 1:234,995,351...235,102,440
JBrowse link
insulin processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpe carboxypeptidase E involved_in
acts_upstream_of_or_within
IDA
IEA
ISO
GO_REF:0000107
MGI:1856395 (MGI:73445|PMID:7663508)
MGI:1856395 (MGI:1099047|PMID:9348219)
Ensembl
RGD
PMID:7663508 PMID:9348219 PMID:2822027 GO_REF:0000107 MGI:1099047 MGI:73445, RGD:1626225 NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233
JBrowse link
G Ero1b endoplasmic reticulum oxidoreductase 1 beta acts_upstream_of_or_within
involved_in
ISO MGI:3864866 (MGI:4440670|PMID:20308425) RGD PMID:20308425 MGI:4440670 NCBI chr17:85,861,086...86,003,244
Ensembl chr17:85,929,618...86,003,398
JBrowse link
G Ins2 insulin 2 involved_in ISO MGI:2442682 (MGI:4818283|PMID:20424817) RGD PMID:20424817 MGI:4818283 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta involved_in ISO MGI:5504624 (MGI:6316718|PMID:31184304) RGD PMID:31184304 MGI:6316718 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 involved_in ISO MGI:2384741 (MGI:2384270|PMID:12136131) RGD PMID:12136131 MGI:2384270 NCBI chr 2:4,395,543...4,442,434
Ensembl chr 2:4,395,543...4,442,434
JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 involved_in ISO (PMID:7626024)
MGI:1857445 (MGI:1195872|PMID:9452465)
RGD PMID:7626024 PMID:9452465 MGI:1195872 NCBI chr 3:130,880,422...131,183,127
Ensembl chr 3:130,880,422...131,183,127
JBrowse link
G Slc30a8 solute carrier family 30 member 8 involved_in ISO
IEA
MGI:4362061 (MGI:4361792|PMID:19706465)
MGI:4362061 (MGI:4361792|PMID:19706465), (MGI:4367958|PMID:19542200)
GO_REF:0000107
RGD
Ensembl
PMID:19542200 PMID:19706465 GO_REF:0000107 MGI:4361792 MGI:4367958 NCBI chr 7:83,591,993...83,627,786
Ensembl chr 7:83,591,993...83,626,305
JBrowse link
G Yipf5 Yip1 domain family, member 5 involved_in ISO
ISS
(PMID:33164986)
GO_REF:0000024
RGD
UniProt
PMID:33164986 GO_REF:0000024 NCBI chr18:32,123,814...32,159,752
Ensembl chr18:32,123,842...32,157,642
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19903
    metabolic process 12212
      primary metabolic process 10968
        protein metabolic process 6116
          insulin metabolic process 17
            insulin catabolic process 4
            insulin processing 8
Path 2
Term Annotations click to browse term
  biological_process 19903
    metabolic process 12212
      organic substance metabolic process 11753
        macromolecule metabolic process 10095
          protein metabolic process 6116
            insulin metabolic process 17
              insulin catabolic process 4
              insulin processing 8
paths to the root