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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
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Accession:GO:1901030 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.
Comment:Caspase 8 may be annotated to this term when it is shown to stimulate MOMP by cleaving the BH3-only protein BID.
Synonyms:exact_synonym: positive regulation of MOMP;   up regulation of MOMP;   up regulation of mitochondrial outer membrane permeabilization;   upregulation of MOMP;   upregulation of mitochondrial outer membrane permeabilization
 narrow_synonym: activation of MOMP;   activation of mitochondrial outer membrane permeabilization
 broad_synonym: positive regulation of mitochondrial outer membrane permeabilization


show annotations for term's descendants           Sort by:
 
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 acts_upstream_of_or_within ISO (MGI:4437986|PMID:19096392) RGD PMID:19096392 MGI:4437986 NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
ISO		 GO_REF:0000024
(MGI:5796067|PMID:26949185)		 UniProt
RGD		 PMID:26949185 GO_REF:0000024 MGI:5796067 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G Chchd10 coiled-coil-helix-coiled-coil-helix domain containing 10 involved_in ISO (PMID:26666268), (PMID:30092269) RGD PMID:26666268 PMID:30092269 NCBI chr20:12,725,839...12,727,638
Ensembl chr20:12,725,842...12,732,763 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISS
ISO		 GO_REF:0000024
(MGI:5514334|PMID:16543145)		 UniProt
RGD		 PMID:16543145 GO_REF:0000024 MGI:5514334 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISS
ISO		 GO_REF:0000024
(MGI:5514334|PMID:16543145)		 UniProt
RGD		 PMID:16543145 GO_REF:0000024 MGI:5514334 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hip1r huntingtin interacting protein 1 related involved_in ISO UniProtKB:Q9HD36 (PMID:19255499) RGD PMID:19255499 NCBI chr12:32,590,164...32,618,841
Ensembl chr12:32,590,165...32,618,734 		JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor involved_in ISO (PMID:15034012) RGD PMID:15034012 NCBI chr 6:131,705,312...131,709,697
Ensembl chr 6:131,705,323...131,709,690 		JBrowse link
G Zfp13 zinc finger protein 13 involved_in ISO (PMID:22306510) RGD PMID:22306510 NCBI chr10:12,615,470...12,623,615
Ensembl chr10:12,615,190...12,623,615 		JBrowse link
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bbc3 Bcl-2 binding component 3 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:17024184)
MGI:2681654 (MGI:3804133|PMID:16705087)		 RGD PMID:16705087 PMID:17024184 PMID:21873635 MGI:3804133, RGD:13792537 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 acts_upstream_of_or_within ISO MGI:2678372 (MGI:2675761|PMID:12952892) RGD PMID:12952892 MGI:2675761 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 acts_upstream_of_or_within ISO (MGI:3607027|PMID:16227588) RGD PMID:16227588 MGI:3607027 NCBI chr 2:233,750,838...233,784,817
Ensembl chr 2:233,750,838...233,784,784 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    positive regulation of biological process 6662
      positive regulation of transport 1125
        positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 11
          positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 3
Path 2
Term Annotations click to browse term
  biological_process 18734
    cellular process 17431
      cellular component organization or biogenesis 6532
        cellular component organization 6307
          organelle organization 3900
            mitochondrion organization 576
              mitochondrial membrane organization 112
                regulation of mitochondrial membrane permeability 62
                  positive regulation of mitochondrial membrane permeability 48
                    mitochondrial outer membrane permeabilization involved in programmed cell death 45
                      positive regulation of mitochondrial membrane permeability involved in apoptotic process 43
                        mitochondrial outer membrane permeabilization 37
                          regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 26
                            positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 11
                              positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 3
paths to the root