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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
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Accession:GO:1901030 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.
Comment:Caspase 8 may be annotated to this term when it is shown to stimulate MOMP by cleaving the BH3-only protein BID.
Synonyms:exact_synonym: positive regulation of MOMP;   up regulation of MOMP;   up regulation of mitochondrial outer membrane permeabilization;   upregulation of MOMP;   upregulation of mitochondrial outer membrane permeabilization
 narrow_synonym: activation of MOMP;   activation of mitochondrial outer membrane permeabilization
 broad_synonym: positive regulation of mitochondrial outer membrane permeabilization


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positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 acts_upstream_of_or_within ISO (MGI:4437986|PMID:19096392) RGD PMID:19096392 MGI:4437986 NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668
JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
ISO
GO_REF:0000024
(MGI:5796067|PMID:26949185)
UniProt
RGD
PMID:26949185 GO_REF:0000024 MGI:5796067 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
JBrowse link
G Chchd10 coiled-coil-helix-coiled-coil-helix domain containing 10 involved_in ISO (PMID:26666268), (PMID:30092269) RGD PMID:26666268 PMID:30092269 NCBI chr20:12,725,839...12,727,638
Ensembl chr20:12,725,842...12,732,763
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISS
ISO
GO_REF:0000024
(MGI:5514334|PMID:16543145)
UniProt
RGD
PMID:16543145 GO_REF:0000024 MGI:5514334 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISS
ISO
GO_REF:0000024
(MGI:5514334|PMID:16543145)
UniProt
RGD
PMID:16543145 GO_REF:0000024 MGI:5514334 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Hip1r huntingtin interacting protein 1 related involved_in ISO UniProtKB:Q9HD36 (PMID:19255499) RGD PMID:19255499 NCBI chr12:32,590,164...32,618,841
Ensembl chr12:32,590,165...32,618,734
JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor involved_in ISO (PMID:15034012) RGD PMID:15034012 NCBI chr 6:131,705,312...131,709,697
Ensembl chr 6:131,705,323...131,709,690
JBrowse link
G Zfp13 zinc finger protein 13 involved_in ISO (PMID:22306510) RGD PMID:22306510 NCBI chr10:12,615,470...12,623,615
Ensembl chr10:12,615,190...12,623,615
JBrowse link
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bbc3 Bcl-2 binding component 3 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2681654 (MGI:3804133|PMID:16705087)
(PMID:17024184)
RGD PMID:16705087 PMID:17024184 PMID:21873635 MGI:3804133, RGD:13792537 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 acts_upstream_of_or_within ISO MGI:2678372 (MGI:2675761|PMID:12952892) RGD PMID:12952892 MGI:2675761 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 acts_upstream_of_or_within ISO (MGI:3607027|PMID:16227588) RGD PMID:16227588 MGI:3607027 NCBI chr 2:233,750,838...233,784,817
Ensembl chr 2:233,750,838...233,784,784
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    positive regulation of biological process 6575
      positive regulation of transport 1102
        positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 11
          positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 3
Path 2
Term Annotations click to browse term
  biological_process 19492
    cellular process 18340
      cellular component organization or biogenesis 6481
        cellular component organization 6235
          organelle organization 3752
            mitochondrion organization 551
              mitochondrial membrane organization 109
                regulation of mitochondrial membrane permeability 59
                  positive regulation of mitochondrial membrane permeability 41
                    mitochondrial outer membrane permeabilization involved in programmed cell death 38
                      positive regulation of mitochondrial membrane permeability involved in apoptotic process 36
                        mitochondrial outer membrane permeabilization 33
                          regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 22
                            positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 11
                              positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 3
paths to the root