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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
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Accession:GO:1901028 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.
Synonyms:exact_synonym: regulation of MOMP
 broad_synonym: regulation of mitochondrial outer membrane permeabilization


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regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO
IEA		 (PMID:18591963)
GO_REF:0000107		 RGD
Ensembl		 PMID:18591963 GO_REF:0000107 NCBI chr 5:155,936,112...155,945,163
Ensembl chr 5:150,652,812...150,661,863 		JBrowse link
G Tmem102 transmembrane protein 102 involved_in ISO
IEA		 (PMID:17828305)
GO_REF:0000107		 RGD
Ensembl		 PMID:17828305 GO_REF:0000107 NCBI chr10:55,022,625...55,025,676
Ensembl chr10:54,523,585...54,525,990 		JBrowse link
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa2 acetyl-CoA acyltransferase 2 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:18371312)		 Ensembl
UniProt
RGD		 PMID:18371312 GO_REF:0000024 GO_REF:0000107 NCBI chr18:70,620,310...70,648,417
Ensembl chr18:68,345,012...68,373,249 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in ISO
IEA		 (PMID:15901672)
GO_REF:0000107		 RGD
Ensembl		 PMID:15901672 GO_REF:0000107 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in ISO (PMID:15901672), (PMID:9393856)
GO_REF:0000114		 RGD
ComplexPortal		 PMID:9393856 PMID:15901672 GO_REF:0000114 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISO
IEA		 (PMID:27098698)
GO_REF:0000107		 RGD
Ensembl		 PMID:27098698 GO_REF:0000107 NCBI chr 9:101,670,729...101,681,834
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G ENSRNOG00000063076 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 7:88,803,047...88,804,403 JBrowse link
G ENSRNOG00000063289 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr10:100,153,638...100,154,558 JBrowse link
G ENSRNOG00000066174 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 1:201,787,072...201,792,824 JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within ISO
IEA		 MGI:104995 (PMID:15288121)
GO_REF:0000107		 RGD
Ensembl		 PMID:15288121 GO_REF:0000107 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:20625543) RGD PMID:20625543 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:20625543) RGD PMID:20625543 NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within ISO
IEA		 (PMID:19096392)
GO_REF:0000107		 RGD
Ensembl		 PMID:19096392 GO_REF:0000107 NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,928,378...2,929,583 		JBrowse link
G Mpv17l MPV17 mitochondrial inner membrane protein like involved_in ISO (PMID:22306510) RGD PMID:22306510 NCBI chr10:2,495,605...2,532,448
Ensembl chr10:1,988,136...2,007,649 		JBrowse link
G Slc25a31 solute carrier family 25 member 31 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:125,623,331...125,639,155
Ensembl chr 2:123,695,408...123,710,795 		JBrowse link
G Slc25a4 solute carrier family 25 member 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:52,805,521...52,809,316
Ensembl chr16:46,072,939...46,076,733 		JBrowse link
G Slc25a5 solute carrier family 25 member 5 involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:19154410)		 UniProt
GO_Central
RGD		 PMID:19154410 GO_REF:0000024 GO_REF:0000033 NCBI chr  X:120,897,616...120,900,683
Ensembl chr  X:116,031,803...116,034,967 		JBrowse link
G Slc25a5-ps9 solute carrier family 25 member 5, pseudogene 9 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:117,110,744...117,111,944
Ensembl chr 3:96,656,151...96,657,400 		JBrowse link
G Slc35f6 solute carrier family 35, member F6 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19154410)		 UniProt
Ensembl
RGD		 PMID:19154410 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:31,445,738...31,457,580
Ensembl chr 6:25,725,819...25,737,730 		JBrowse link
G Tmem14a transmembrane protein 14A involved_in ISO (PMID:21723035) RGD PMID:21723035 NCBI chr 9:31,137,011...31,148,794
Ensembl chr 9:23,733,039...23,734,463
Ensembl chr 9:23,733,039...23,734,463 		JBrowse link
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 acts_upstream_of_or_within ISO (PMID:19096392) RGD PMID:19096392 NCBI chr 5:150,022,960...150,026,677
Ensembl chr 5:144,738,950...144,742,668 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:26949185)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:26949185 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:101,670,729...101,681,834
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G Chchd10 coiled-coil-helix-coiled-coil-helix domain containing 10 involved_in ISO (PMID:26666268), (PMID:30092269) RGD PMID:26666268 PMID:30092269 NCBI chr20:12,725,274...12,730,295
Ensembl chr20:12,725,842...12,732,763 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISS
ISO		 GO_REF:0000024
(PMID:16543145)		 UniProt
RGD		 PMID:16543145 GO_REF:0000024 NCBI chr 1:89,943,669...89,953,514
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISS
ISO		 GO_REF:0000024
(PMID:16543145)		 UniProt
RGD		 PMID:16543145 GO_REF:0000024 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hip1r huntingtin interacting protein 1 related involved_in ISO
IEA		 UniProtKB:Q9HD36 (PMID:19255499)
GO_REF:0000107		 RGD
Ensembl		 PMID:19255499 GO_REF:0000107 NCBI chr12:38,251,085...38,279,756
Ensembl chr12:32,590,165...32,618,734 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:21370995) RGD PMID:21370995 NCBI chr 7:124,706,246...124,867,234
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor involved_in ISO (PMID:15034012) RGD PMID:15034012 NCBI chr 6:137,526,416...137,530,790
Ensembl chr 6:131,705,323...131,709,690 		JBrowse link
G Zfp13 zinc finger protein 13 involved_in ISO
IEA		 (PMID:22306510)
GO_REF:0000107		 RGD
Ensembl		 PMID:22306510 GO_REF:0000107 NCBI chr10:13,119,707...13,128,284
Ensembl chr10:12,615,190...12,623,615 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    localization 5728
      regulation of localization 2400
        regulation of transport 1970
          regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 28
            negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 18
            positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 9
Path 2
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      cellular component organization or biogenesis 7104
        cellular component organization 6817
          organelle organization 3713
            mitochondrion organization 483
              mitochondrial membrane organization 122
                regulation of mitochondrial membrane permeability 65
                  positive regulation of mitochondrial membrane permeability 49
                    mitochondrial outer membrane permeabilization involved in programmed cell death 45
                      positive regulation of mitochondrial membrane permeability involved in apoptotic process 43
                        mitochondrial outer membrane permeabilization 36
                          regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 28
                            negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 18
                            positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 9
paths to the root