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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of purine nucleotide metabolic process
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Accession:GO:1900544 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of purine nucleotide metabolic process.
Synonyms:exact_synonym: positive regulation of purine nucleotide metabolism;   up regulation of purine nucleotide metabolic process;   up regulation of purine nucleotide metabolism;   upregulation of purine nucleotide metabolic process;   upregulation of purine nucleotide metabolism
 narrow_synonym: activation of purine metabolic process;   activation of purine metabolism;   activation of purine nucleotide metabolic process;   activation of purine nucleotide metabolism;   positive regulation of purine metabolic process;   positive regulation of purine metabolism;   up regulation of purine metabolic process;   up regulation of purine metabolism;   upregulation of purine metabolic process;   upregulation of purine metabolism



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positive regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2L1 BCL2 like 1 involved_in ISO PMID:23792689 CAFA PMID:23792689 RGD:12793033 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G ENO1 enolase 1 involved_in IGI
IDA
(PMID:15459207) CAFA PMID:15459207 NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190
JBrowse link
G IL4 interleukin 4 involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 involved_in ISO PMID:15459207 CAFA PMID:15459207 RGD:12793039 NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,544
JBrowse link
G MT-CO2 mitochondrially encoded cytochrome c oxidase II involved_in IEA
ISO
Ensembl
RGD
PMID:19306371 GO_REF:0000107 RGD:13506652 NCBI chr MT:7,586...8,269
Ensembl chr MT:7,586...8,269
JBrowse link
G MTCO2P12 MT-CO2 pseudogene 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:632,757...633,438
Ensembl chr 1:632,757...633,438
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in ISO
IEA
RGD
Ensembl
PMID:22629444 GO_REF:0000107 RGD:7240532 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G NDUFC2 NADH:ubiquinone oxidoreductase subunit C2 ISO RGD PMID:26888427 RGD:11040458 NCBI chr11:78,068,297...78,079,862
Ensembl chr11:78,068,297...78,079,862
JBrowse link
G PID1 phosphotyrosine interaction domain containing 1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 2:229,023,973...229,271,287
Ensembl chr 2:228,850,526...229,271,287
JBrowse link
G PINK1 PTEN induced kinase 1 involved_in TAS (PMID:20871098) ParkinsonsUK-UCL PMID:20871098 NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha acts_upstream_of IMP (PMID:31574452) ARUK-UCL PMID:31574452 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,756
JBrowse link
G PPARGC1A PPARG coactivator 1 alpha involved_in ISS UniProt GO_REF:0000024 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:24096089 RGD:10413842 NCBI chr 6:161,347,417...162,727,802
Ensembl chr 6:161,347,417...162,727,775
JBrowse link
G SIRT1 sirtuin 1 involved_in ISO (PMID:24747689) AgBase PMID:24747689 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
JBrowse link
G SLC25A12 solute carrier family 25 member 12 involved_in IEA
ISO
Ensembl
RGD
PMID:19764902 GO_REF:0000107 RGD:13628741 NCBI chr 2:171,783,405...171,894,244
Ensembl chr 2:171,783,405...171,999,859
JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in ISO
IEA
RGD
Ensembl
PMID:23590160 GO_REF:0000107 RGD:8694322 NCBI chr17:42,313,324...42,388,502
Ensembl chr17:42,313,324...42,388,540
JBrowse link
G TAFAZZIN tafazzin, phospholipid-lysophospholipid transacylase involved_in IEA
ISO
Ensembl
RGD
PMID:20348225 GO_REF:0000107 RGD:13432160 NCBI chr  X:154,411,539...154,421,726
Ensembl chr  X:154,411,524...154,421,726
JBrowse link
G TMSB4X thymosin beta 4 X-linked involved_in IDA (PMID:21106936) CAFA PMID:21106936 NCBI chr  X:12,975,110...12,977,223
Ensembl chr  X:12,975,110...12,977,227
JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186
JBrowse link
G VCP valosin containing protein involved_in IMP (PMID:23498975) ParkinsonsUK-UCL PMID:23498975 NCBI chr 9:35,056,064...35,072,625
Ensembl chr 9:35,053,928...35,072,668
JBrowse link
positive regulation of glycolytic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APP amyloid beta precursor protein involved_in IGI (PMID:29061364) ARUK-UCL PMID:29061364 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,550...26,171,128
JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator involved_in IC (PMID:8089148) BHF-UCL PMID:8089148 NCBI chr 1:150,809,713...150,876,737
Ensembl chr 1:150,809,713...150,876,708
JBrowse link
G ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) involved_in ISS UniProt GO_REF:0000024 NCBI chr14:73,955,329...74,019,326
Ensembl chr14:73,958,010...74,019,399
JBrowse link
G ESRRB estrogen related receptor beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:76,371,271...76,501,839
Ensembl chr14:76,310,712...76,501,837
JBrowse link
G GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic involved_in TAS (PMID:10714828) UniProt PMID:10714828 NCBI chr19:35,533,456...35,545,319
Ensembl chr19:35,533,455...35,545,319
JBrowse link
G GCK glucokinase ISO RGD PMID:17553851 RGD:2301905 NCBI chr 7:44,143,213...44,189,439
Ensembl chr 7:44,143,213...44,198,170
JBrowse link
G GPD1 glycerol-3-phosphate dehydrogenase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1927687|PMID:11147825) Ensembl
MGI
PMID:11147825 GO_REF:0000107 MGI:1927687 NCBI chr12:50,104,008...50,111,313
Ensembl chr12:50,103,982...50,111,313
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in IC (PMID:8089148) BHF-UCL PMID:8089148 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3766710|PMID:17408640) Ensembl
MGI
PMID:17408640 GO_REF:0000107 MGI:3766710 NCBI chr13:46,831,546...46,898,082
Ensembl chr13:46,831,546...46,897,076
JBrowse link
G IFNG interferon gamma involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IGF1 insulin like growth factor 1 involved_in IDA (PMID:7688386) BHF-UCL PMID:7688386 NCBI chr12:102,395,860...102,481,839
Ensembl chr12:102,395,874...102,481,744
JBrowse link
G INS insulin involved_in IMP
IDA
(PMID:381941)
(PMID:7688386)
BHF-UCL PMID:381941 PMID:7688386 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
JBrowse link
G INSR insulin receptor involved_in IMP (PMID:7693131) BHF-UCL PMID:7693131 NCBI chr19:7,112,257...7,294,414
Ensembl chr19:7,112,255...7,294,414
JBrowse link
G MIF macrophage migration inhibitory factor ISO RGD PMID:11086030 RGD:1642010 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227
JBrowse link
G MLXIPL MLX interacting protein like involved_in IMP (PMID:19995986) BHF-UCL PMID:19995986 NCBI chr 7:73,593,201...73,624,522
Ensembl chr 7:73,593,194...73,624,543
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in ISO
IEA
RGD
Ensembl
PMID:22842522 GO_REF:0000107 RGD:7207891 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G P2RX7 purinergic receptor P2X 7 involved_in IMP (PMID:22898868) CACAO PMID:22898868 NCBI chr12:121,132,819...121,188,032
Ensembl chr12:121,132,819...121,188,032
JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,379...40,798,374
JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:56,645,314...56,715,335
Ensembl chr 1:56,645,314...56,715,335
JBrowse link
G PRXL2C peroxiredoxin like 2C involved_in IMP (PMID:29901208) UniProt PMID:29901208 NCBI chr 9:96,639,577...96,655,331
Ensembl chr 9:96,639,577...96,655,317
JBrowse link
G PSEN1 presenilin 1 involved_in IGI (PMID:29061364) ARUK-UCL PMID:29061364 NCBI chr14:73,136,436...73,223,691
Ensembl chr14:73,136,418...73,223,691
JBrowse link
G SLC4A4 solute carrier family 4 member 4 acts_upstream_of IGI
ISS
(PMID:21976511) ARUK-UCL PMID:21976511 NCBI chr 4:71,062,646...71,572,083
Ensembl chr 4:71,062,667...71,572,087
JBrowse link
G ZBTB20 zinc finger and BTB domain containing 20 involved_in ISS UniProt GO_REF:0000024 NCBI chr 3:114,314,500...115,147,288
Ensembl chr 3:114,314,500...115,147,288
JBrowse link
positive regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2B adenosine A2b receptor acts_upstream_of_or_within ISO (MGI:3794903|PMID:18340377) MGI PMID:18340377 MGI:3794903 NCBI chr17:15,927,782...15,975,746
Ensembl chr17:15,945,130...15,975,746
JBrowse link
G GUCA1A guanylate cyclase activator 1A involved_in ISS
IEA
ISO
UniProt
GOC
RGD
PMID:12545196 GO_REF:0000024 GO_REF:0000108 RGD:1599357 NCBI chr 6:42,173,364...42,180,056
Ensembl chr 6:42,155,406...42,181,338
JBrowse link
G GUCA1ANB GUCA1A neighbor involved_in IEA GOC GO_REF:0000108 NCBI chr 6:42,155,406...42,163,418
Ensembl chr 6:42,155,406...42,180,056
JBrowse link
G GUCA1B guanylate cyclase activator 1B involved_in IEA GOC GO_REF:0000108 NCBI chr 6:42,183,284...42,194,956
Ensembl chr 6:42,183,284...42,194,956
JBrowse link
G GUCA1C guanylate cyclase activator 1C involved_in IEA GOC GO_REF:0000108 NCBI chr 3:108,907,644...108,955,195
Ensembl chr 3:108,907,792...108,953,879
JBrowse link
G GUCA2A guanylate cyclase activator 2A involved_in IEA GOC GO_REF:0000108 NCBI chr 1:42,162,690...42,164,745
Ensembl chr 1:42,162,690...42,164,745
JBrowse link
G GUCA2B guanylate cyclase activator 2B involved_in IEA GOC GO_REF:0000108 NCBI chr 1:42,153,410...42,155,820
Ensembl chr 1:42,153,410...42,155,820
JBrowse link
G LOC118142757 GUCA1ANB-GUCA1A readthrough involved_in ISS UniProt GO_REF:0000024 NCBI chr 6:42,155,406...42,180,056
Ensembl chr 6:42,155,406...42,181,338
JBrowse link
G NOS1 nitric oxide synthase 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170
JBrowse link
G NOS2 nitric oxide synthase 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NOS3 nitric oxide synthase 3 involved_in IBA
ISS
IMP
(PMID:21873635)
(PMID:17502619)
GO_Central
BHF-UCL
PMID:17502619 PMID:21873635 GO_REF:0000024 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G RCVRN recoverin involved_in IEA GOC GO_REF:0000108 NCBI chr17:9,896,320...9,905,271
Ensembl chr17:9,896,320...9,905,271
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18539
    metabolic process 11872
      positive regulation of metabolic process 3999
        positive regulation of small molecule metabolic process 173
          positive regulation of nucleotide metabolic process 54
            positive regulation of purine nucleotide metabolic process 54
              positive regulation of glycolytic process + 23
              positive regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
              positive regulation of purine nucleotide biosynthetic process + 32
              positive regulation of purine nucleotide catabolic process + 0
              positive regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA 0
Path 2
Term Annotations click to browse term
  biological_process 18539
    metabolic process 11872
      cellular metabolic process 10812
        cellular aromatic compound metabolic process 6018
          nucleobase-containing compound metabolic process 5775
            nucleobase-containing small molecule metabolic process 616
              nucleoside phosphate metabolic process 537
                nucleotide metabolic process 528
                  regulation of nucleotide metabolic process 99
                    positive regulation of nucleotide metabolic process 54
                      positive regulation of purine nucleotide metabolic process 54
                        positive regulation of glycolytic process + 23
                        positive regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
                        positive regulation of purine nucleotide biosynthetic process + 32
                        positive regulation of purine nucleotide catabolic process + 0
                        positive regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA 0
paths to the root