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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of purine nucleotide metabolic process
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Accession:GO:1900543 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process.
Synonyms:exact_synonym: down regulation of purine nucleotide metabolic process;   down regulation of purine nucleotide metabolism;   downregulation of purine nucleotide metabolic process;   downregulation of purine nucleotide metabolism;   negative regulation of purine nucleotide metabolism
 narrow_synonym: down regulation of purine metabolic process;   down regulation of purine metabolism;   downregulation of purine metabolic process;   downregulation of purine metabolism;   inhibition of purine metabolic process;   inhibition of purine metabolism;   inhibition of purine nucleotide metabolic process;   inhibition of purine nucleotide metabolism;   negative regulation of purine metabolic process;   negative regulation of purine metabolism


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negative regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 ISO RGD PMID:21325440 RGD:9685453 NCBI chrNW_004624737:7,011,792...7,193,903
Ensembl chrNW_004624737:7,084,818...7,191,918
JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 involved_in ISO (PMID:24289924) ParkinsonsUK-UCL PMID:24289924 NCBI chrNW_004624807:446,662...478,571
Ensembl chrNW_004624807:446,647...479,069
JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 involved_in ISO (PMID:20165904) BHF-UCL PMID:20165904 NCBI chrNW_004624843:2,926,116...3,165,325
Ensembl chrNW_004624843:2,931,282...3,186,615
JBrowse link
negative regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fis1 fission, mitochondrial 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624740:16,052,777...16,056,438
Ensembl chrNW_004624740:16,052,820...16,057,098
JBrowse link
G Tspo translocator protein involved_in ISO (MGI:5689082|PMID:25470454) ParkinsonsUK-UCL PMID:25470454 MGI:5689082 NCBI chrNW_004624752:5,814,784...5,820,250
Ensembl chrNW_004624752:5,814,784...5,820,141
JBrowse link
negative regulation of glycolytic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in ISO (MGI:3759354|PMID:17828264) UniProt PMID:17828264 MGI:3759354 NCBI chrNW_004624767:19,844,996...19,859,274
Ensembl chrNW_004624767:19,844,884...19,858,950
JBrowse link
G Cbfa2t3 CBFA2/RUNX1 partner transcriptional co-repressor 3 involved_in ISO (PMID:23840896) UniProt PMID:23840896 NCBI chrNW_004624746:716,848...773,169
Ensembl chrNW_004624746:716,836...773,169
JBrowse link
G Ddit4 DNA damage inducible transcript 4 acts_upstream_of_or_within ISO (PMID:20176937) MGI PMID:20176937 NCBI chrNW_004624754:6,091,914...6,094,035
Ensembl chrNW_004624754:6,091,809...6,094,525
JBrowse link
G Fbp1 fructose-bisphosphatase 1 involved_in ISO (PMID:25043030)
(PMID:19881551)
CAFA
UniProt
PMID:19881551 PMID:25043030 NCBI chrNW_004624753:16,019,546...16,048,096
Ensembl chrNW_004624753:16,016,022...16,048,104
JBrowse link
G Flcn folliculin involved_in ISO (PMID:34381247) UniProt PMID:34381247 NCBI chrNW_004624849:4,157,683...4,179,724 JBrowse link
G Git1 GIT ArfGAP 1 involved_in ISO (MGI:6478067|PMID:32460388) UniProt PMID:32460388 MGI:6478067 NCBI chrNW_004624786:2,071,376...2,086,929
Ensembl chrNW_004624786:2,071,382...2,086,910
JBrowse link
G Hdac4 histone deacetylase 4 involved_in ISO (MGI:4365327|PMID:19109424) BHF-UCL PMID:19109424 MGI:4365327 NCBI chrNW_004624847:3,846,196...4,101,537
Ensembl chrNW_004624847:3,845,858...4,101,487
JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within ISO (PMID:19096392) MGI PMID:19096392 NCBI chrNW_004624754:24,991,650...24,992,645
Ensembl chrNW_004624754:24,991,690...24,992,643
JBrowse link
G Mtch2 mitochondrial carrier 2 acts_upstream_of_or_within ISO (PMID:26219591) MGI PMID:26219591 NCBI chrNW_004624767:1,199,367...1,218,425
Ensembl chrNW_004624767:1,199,291...1,221,123
JBrowse link
G Myog myogenin ISO RGD PMID:10225962 RGD:9686132 NCBI chrNW_004624807:7,742,926...7,753,149
Ensembl chrNW_004624807:7,749,852...7,753,336
JBrowse link
G Ncor1 nuclear receptor corepressor 1 involved_in ISO (PMID:19955185) BHF-UCL PMID:19955185 NCBI chrNW_004624877:4,203,125...4,379,891
Ensembl chrNW_004624877:4,233,282...4,377,211
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator involved_in ISO (PMID:30451898) UniProt PMID:30451898 NCBI chrNW_004624782:13,042,938...13,044,298
Ensembl chrNW_004624782:13,042,939...13,044,267
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624752:3,646,499...3,702,553
Ensembl chrNW_004624752:3,650,922...3,701,672
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha ISO RGD PMID:22343369 RGD:7242186 NCBI chrNW_004624755:7,826,219...8,460,746
Ensembl chrNW_004624755:8,375,596...8,465,297
JBrowse link
G Sik2 salt inducible kinase 2 involved_in ISO (PMID:21084751) MGI PMID:21084751 NCBI chrNW_004624784:6,728,504...6,900,557
Ensembl chrNW_004624784:6,745,595...6,895,747
JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (PMID:26456828)
(MGI:4881401|PMID:20141841), (MGI:5619441|PMID:23217706)
UniProt
CACAO
PMID:20141841 PMID:23217706 PMID:26456828 MGI:4881401 MGI:5619441 NCBI chrNW_004624828:5,441,973...5,449,549
Ensembl chrNW_004624828:5,442,057...5,451,520
JBrowse link
G Stat3 signal transducer and activator of transcription 3 acts_upstream_of_or_within ISO (PMID:22891351) MGI PMID:22891351 NCBI chrNW_004624795:1,648,235...1,680,788
Ensembl chrNW_004624795:1,648,080...1,681,200
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:20935145) TreeGrafter
MGI
PMID:20935145 GO_REF:0000118 NCBI chrNW_004624860:1,416,419...1,455,953
Ensembl chrNW_004624860:1,417,131...1,457,717
JBrowse link
G Trim63 tripartite motif containing 63 involved_in ISO (PMID:34244144) FlyBase PMID:34244144 NCBI chrNW_004624764:10,126,345...10,139,829
Ensembl chrNW_004624764:10,128,751...10,139,687
JBrowse link
negative regulation of glycolytic process through fructose-6-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 involved_in ISO (PMID:15331593)
(PMID:16155866)
MGI PMID:15331593 PMID:16155866 NCBI chrNW_004624910:303,697...380,491
Ensembl chrNW_004624910:305,068...380,188
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624733:38,012,694...38,033,745
Ensembl chrNW_004624733:38,012,392...38,036,914
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in ISO (PMID:16155866)
(PMID:23292513)
MGI PMID:16155866 PMID:23292513 NCBI chrNW_004624901:1,319,426...1,336,848
Ensembl chrNW_004624901:1,319,062...1,336,744
JBrowse link
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) acts_upstream_of_or_within ISO (PMID:18698006) MGI PMID:18698006 NCBI chrNW_004624795:739,821...752,773
Ensembl chrNW_004624795:743,646...752,103
JBrowse link
negative regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hpca hippocalcin ISO RGD PMID:15336960 RGD:9686438 NCBI chrNW_004624764:15,990,910...15,999,617
Ensembl chrNW_004624764:15,990,729...15,999,615
JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldob aldolase, fructose-bisphosphate B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624758:9,868,223...9,880,205
Ensembl chrNW_004624758:9,868,260...9,880,205
JBrowse link
G Tp53 tumor protein p53 involved_in ISO (PMID:21336310) CACAO PMID:21336310 NCBI chrNW_004624786:10,266,316...10,282,664
Ensembl chrNW_004624786:10,263,518...10,271,218
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15053
    metabolic process 9053
      small molecule metabolic process 1508
        negative regulation of small molecule metabolic process 105
          negative regulation of nucleotide metabolic process 32
            negative regulation of purine nucleotide metabolic process 31
              negative regulation of ATP metabolic process + 28
              negative regulation of NAD metabolic process + 0
              negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
              negative regulation of pentose-phosphate shunt 2
              negative regulation of purine nucleotide biosynthetic process + 4
              negative regulation of purine nucleotide catabolic process + 23
              negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA 0
Path 2
Term Annotations click to browse term
  biological_process 15053
    metabolic process 9053
      cellular metabolic process 7502
        phosphorus metabolic process 1640
          phosphate-containing compound metabolic process 1616
            nucleoside phosphate metabolic process 492
              nucleotide metabolic process 488
                regulation of nucleotide metabolic process 98
                  negative regulation of nucleotide metabolic process 32
                    negative regulation of purine nucleotide metabolic process 31
                      negative regulation of ATP metabolic process + 28
                      negative regulation of NAD metabolic process + 0
                      negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
                      negative regulation of pentose-phosphate shunt 2
                      negative regulation of purine nucleotide biosynthetic process + 4
                      negative regulation of purine nucleotide catabolic process + 23
                      negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA 0
paths to the root