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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of purine nucleotide metabolic process
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Accession:GO:1900543 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process.
Synonyms:exact_synonym: down regulation of purine nucleotide metabolic process;   down regulation of purine nucleotide metabolism;   downregulation of purine nucleotide metabolic process;   downregulation of purine nucleotide metabolism;   negative regulation of purine nucleotide metabolism
 narrow_synonym: down regulation of purine metabolic process;   down regulation of purine metabolism;   downregulation of purine metabolic process;   downregulation of purine metabolism;   inhibition of purine metabolic process;   inhibition of purine metabolism;   inhibition of purine nucleotide metabolic process;   inhibition of purine nucleotide metabolism;   negative regulation of purine metabolic process;   negative regulation of purine metabolism



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negative regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 involved_in ISO RGD
MGI
PMID:21325440 GO_REF:0000096 MGI:4417868 RGD:9685453 NCBI chr19:40,600,810...40,730,046
Ensembl chr19:40,600,810...40,730,046
JBrowse link
G Mir675 microRNA 675 acts_upstream_of ISO (PMID:31574452) ARUK-UCL PMID:31574452 NCBI chr 7:142,130,801...142,130,884
Ensembl chr 7:142,130,801...142,130,884
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:84,014,014...84,317,550
Ensembl chr 1:84,014,017...84,341,901
JBrowse link
negative regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fis1 fission, mitochondrial 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:136,982,129...136,995,088
Ensembl chr 5:136,982,129...136,995,088
JBrowse link
G Tspo translocator protein involved_in IMP (MGI:5689082|PMID:25470454) ParkinsonsUK-UCL PMID:25470454 MGI:5689082 NCBI chr15:83,447,774...83,458,404
Ensembl chr15:83,447,793...83,458,404
JBrowse link
negative regulation of glycolytic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in IMP (MGI:3759354|PMID:17828264) UniProt PMID:17828264 MGI:3759354 NCBI chr19:4,911,244...4,927,937
Ensembl chr19:4,911,244...4,927,937
JBrowse link
G Cbfa2t3 CBFA2/RUNX1 translocation partner 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:123,351,875...123,426,069
Ensembl chr 8:123,351,880...123,425,848
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 acts_upstream_of_or_within IMP (PMID:20176937) MGI PMID:20176937 NCBI chr10:59,785,497...59,787,592
Ensembl chr10:59,785,491...59,787,656
JBrowse link
G Fbp1 fructose bisphosphatase 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr13:63,012,567...63,036,112
Ensembl chr13:63,012,567...63,036,096
JBrowse link
G Flcn folliculin involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:59,682,234...59,706,138
Ensembl chr11:59,682,234...59,700,842
JBrowse link
G Git1 GIT ArfGAP 1 involved_in IMP (MGI:6478067|PMID:32460388) UniProt PMID:32460388 MGI:6478067 NCBI chr11:77,384,114...77,398,600
Ensembl chr11:77,384,388...77,398,612
JBrowse link
G Hdac4 histone deacetylase 4 involved_in IMP (MGI:4365327|PMID:19109424) BHF-UCL PMID:19109424 MGI:4365327 NCBI chr 1:91,856,501...92,123,424
Ensembl chr 1:91,856,501...92,123,421
JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within IMP (PMID:19096392) MGI PMID:19096392 NCBI chr17:36,132,605...36,133,803
Ensembl chr17:36,132,576...36,133,815
JBrowse link
G Mtch2 mitochondrial carrier 2 acts_upstream_of_or_within IMP (PMID:26219591) MGI PMID:26219591 NCBI chr 2:90,677,434...90,697,154
Ensembl chr 2:90,677,499...90,697,154
JBrowse link
G Myog myogenin involved_in ISO RGD
MGI
PMID:10225962 GO_REF:0000096 MGI:4417868 RGD:9686132 NCBI chr 1:134,217,742...134,220,286
Ensembl chr 1:134,217,727...134,220,286
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:62,207,132...62,348,200
Ensembl chr11:62,207,252...62,349,367
JBrowse link
G Nupr1 nuclear protein transcription regulator 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:126,222,418...126,224,642
Ensembl chr 7:126,222,421...126,230,033
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha involved_in ISO RGD
MGI
PMID:22343369 GO_REF:0000096 MGI:4417868 RGD:7242186 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
JBrowse link
G Sik2 salt inducible kinase 2 involved_in IMP (PMID:21084751) MGI PMID:21084751 NCBI chr 9:50,800,944...50,920,432
Ensembl chr 9:50,804,101...50,920,373
JBrowse link
G Sirt6 sirtuin 6 involved_in IMP
ISO
(MGI:4881401|PMID:20141841), (MGI:5619441|PMID:23217706) CACAO
MGI
PMID:20141841 PMID:23217706 GO_REF:0000119 MGI:4834177 MGI:4881401 MGI:5619441 NCBI chr10:81,457,621...81,463,631
Ensembl chr10:81,457,619...81,463,631
JBrowse link
G Stat3 signal transducer and activator of transcription 3 acts_upstream_of_or_within IMP (PMID:22891351) MGI PMID:22891351 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
JBrowse link
G Tigar Trp53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within
involved_in
IDA
IBA
(PMID:20935145) MGI
GO_Central
PMID:20935145 GO_REF:0000033 NCBI chr 6:127,062,079...127,086,564
Ensembl chr 6:127,062,079...127,086,520
JBrowse link
G Trim63 tripartite motif-containing 63 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:134,042,431...134,056,940
Ensembl chr 4:134,042,431...134,056,940
JBrowse link
negative regulation of glycolytic process through fructose-6-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 involved_in IMP
IGI
(PMID:15331593)
(PMID:16155866)
MGI PMID:15331593 PMID:16155866 NCBI chr  X:149,370,441...149,426,874
Ensembl chr  X:149,371,225...149,426,874
JBrowse link
G Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform involved_in IMP (PMID:32192773) MGI PMID:32192773 NCBI chr11:51,989,651...52,013,576
Ensembl chr11:51,989,508...52,018,605
JBrowse link
G Prkaca protein kinase, cAMP dependent, catalytic, alpha involved_in IMP
IDA
(PMID:16155866)
(PMID:23292513)
MGI PMID:16155866 PMID:23292513 NCBI chr 8:84,699,607...84,723,073
Ensembl chr 8:84,699,622...84,723,072
JBrowse link
G Slc4a1 solute carrier family 4 (anion exchanger), member 1 acts_upstream_of_or_within IMP (PMID:18698006) MGI PMID:18698006 NCBI chr11:102,239,646...102,256,107
Ensembl chr11:102,239,650...102,257,029
JBrowse link
negative regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hpca hippocalcin ISO RGD PMID:15336960 RGD:9686438 NCBI chr 4:129,005,363...129,019,712
Ensembl chr 4:129,005,363...129,015,829
JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldob aldolase B, fructose-bisphosphate involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:49,535,993...49,549,546
Ensembl chr 4:49,535,995...49,549,546
JBrowse link
G Trp53 transformation related protein 53 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28580
    metabolic process 11029
      small molecule metabolic process 1868
        negative regulation of small molecule metabolic process 133
          negative regulation of nucleotide metabolic process 33
            negative regulation of purine nucleotide metabolic process 32
              negative regulation of ATP metabolic process + 29
              negative regulation of NAD metabolic process + 0
              negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
              negative regulation of pentose-phosphate shunt 2
              negative regulation of purine nucleotide biosynthetic process + 5
              negative regulation of purine nucleotide catabolic process + 23
              negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA 0
Path 2
Term Annotations click to browse term
  biological_process 28580
    metabolic process 11029
      cellular metabolic process 9228
        phosphorus metabolic process 1894
          phosphate-containing compound metabolic process 1864
            nucleoside phosphate metabolic process 611
              nucleotide metabolic process 603
                regulation of nucleotide metabolic process 107
                  negative regulation of nucleotide metabolic process 33
                    negative regulation of purine nucleotide metabolic process 32
                      negative regulation of ATP metabolic process + 29
                      negative regulation of NAD metabolic process + 0
                      negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
                      negative regulation of pentose-phosphate shunt 2
                      negative regulation of purine nucleotide biosynthetic process + 5
                      negative regulation of purine nucleotide catabolic process + 23
                      negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA 0
paths to the root