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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of purine nucleotide metabolic process
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Accession:GO:1900543 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process.
Synonyms:exact_synonym: down regulation of purine nucleotide metabolic process;   down regulation of purine nucleotide metabolism;   downregulation of purine nucleotide metabolic process;   downregulation of purine nucleotide metabolism;   negative regulation of purine nucleotide metabolism
 narrow_synonym: down regulation of purine metabolic process;   down regulation of purine metabolism;   downregulation of purine metabolic process;   downregulation of purine metabolism;   inhibition of purine metabolic process;   inhibition of purine metabolism;   inhibition of purine nucleotide metabolic process;   inhibition of purine nucleotide metabolism;   negative regulation of purine metabolic process;   negative regulation of purine metabolism



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negative regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 ISO RGD PMID:21325440 RGD:9685453 NCBI chr10:95,694,186...95,877,266
Ensembl chr10:95,711,779...95,877,266
JBrowse link
G MIR675 microRNA 675 acts_upstream_of IMP (PMID:31574452) ARUK-UCL PMID:31574452 NCBI chr11:1,996,759...1,996,831
Ensembl chr11:1,996,759...1,996,831
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in IMP (PMID:24289924) ParkinsonsUK-UCL PMID:24289924 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link
G PID1 phosphotyrosine interaction domain containing 1 involved_in IMP (PMID:20165904) BHF-UCL PMID:20165904 NCBI chr 2:229,023,973...229,271,287
Ensembl chr 2:228,850,526...229,271,287
JBrowse link
negative regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FIS1 fission, mitochondrial 1 involved_in IMP (PMID:32521232) ARUK-UCL PMID:32521232 NCBI chr 7:101,239,472...101,245,081
Ensembl chr 7:101,239,458...101,252,316
JBrowse link
G TSPO translocator protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:43,151,559...43,163,242
Ensembl chr22:43,151,547...43,163,242
JBrowse link
negative regulation of glycolytic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr11:66,546,395...66,563,334
Ensembl chr11:66,546,395...66,563,334
JBrowse link
G CBFA2T3 CBFA2/RUNX1 partner transcriptional co-repressor 3 involved_in IDA (PMID:23840896) UniProt PMID:23840896 NCBI chr16:88,874,858...88,977,207
Ensembl chr16:88,874,858...88,977,207
JBrowse link
G DDIT4 DNA damage inducible transcript 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:20176937) Ensembl
MGI
PMID:20176937 GO_REF:0000107 NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,919...72,276,036
JBrowse link
G FBP1 fructose-bisphosphatase 1 involved_in IMP
IDA
(PMID:25043030)
(PMID:19881551)
CAFA
UniProt
PMID:19881551 PMID:25043030 NCBI chr 9:94,603,133...94,640,263
Ensembl chr 9:94,603,133...94,640,249
JBrowse link
G FLCN folliculin involved_in IDA (PMID:34381247) UniProt PMID:34381247 NCBI chr17:17,212,212...17,237,330
Ensembl chr17:17,212,212...17,237,188
JBrowse link
G GIT1 GIT ArfGAP 1 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr17:29,573,475...29,589,648
Ensembl chr17:29,573,475...29,594,054
JBrowse link
G HDAC4 histone deacetylase 4 involved_in IEA
ISS
Ensembl
BHF-UCL
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:239,048,168...239,401,649
Ensembl chr 2:239,048,168...239,401,654
JBrowse link
G IER3 immediate early response 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19096392) Ensembl
MGI
PMID:19096392 GO_REF:0000107 NCBI chr 6:30,743,199...30,744,547
Ensembl chr 6:30,743,199...30,744,548
JBrowse link
G MTCH2 mitochondrial carrier 2 acts_upstream_of_or_within ISO (PMID:26219591) MGI PMID:26219591 NCBI chr11:47,604,317...47,642,559
Ensembl chr11:47,617,315...47,642,607
JBrowse link
G MYOG myogenin ISO RGD PMID:10225962 RGD:9686132 NCBI chr 1:203,083,129...203,086,012
Ensembl chr 1:203,083,129...203,086,012
JBrowse link
G NCOR1 nuclear receptor corepressor 1 involved_in IMP (PMID:19955185) BHF-UCL PMID:19955185 NCBI chr17:16,029,157...16,215,534
Ensembl chr17:16,029,065...16,218,185
JBrowse link
G NUPR1 nuclear protein 1, transcriptional regulator involved_in IMP (PMID:30451898) UniProt PMID:30451898 NCBI chr16:28,532,708...28,538,974
Ensembl chr16:28,532,708...28,539,008
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha involved_in IDA (PMID:19955185) BHF-UCL PMID:19955185 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO RGD PMID:22343369 RGD:7242186 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089
JBrowse link
G SIK2 salt inducible kinase 2 involved_in ISO (PMID:21084751) MGI PMID:21084751 NCBI chr11:111,602,449...111,730,855
Ensembl chr11:111,602,449...111,730,855
JBrowse link
G SIRT6 sirtuin 6 involved_in IEA
IDA
(PMID:26456828) Ensembl
UniProt
PMID:26456828 GO_REF:0000107 NCBI chr19:4,174,109...4,182,563
Ensembl chr19:4,174,109...4,182,566
JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22891351) Ensembl
MGI
PMID:22891351 GO_REF:0000107 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568
JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
(PMID:20935145) Ensembl
MGI
GO_Central
PMID:20935145 GO_REF:0000033 GO_REF:0000107 NCBI chr12:4,321,213...4,360,028
Ensembl chr12:4,307,763...4,360,028
JBrowse link
G TRIM63 tripartite motif containing 63 involved_in IMP (PMID:34244144) FlyBase PMID:34244144 NCBI chr 1:26,051,301...26,067,630
Ensembl chr 1:26,051,301...26,068,436
JBrowse link
negative regulation of glycolytic process through fructose-6-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:54,932,961...54,998,789
Ensembl chr  X:54,932,961...54,998,534
JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:134,194,332...134,226,073
Ensembl chr 5:134,194,035...134,226,073
JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:14,091,688...14,117,762
Ensembl chr19:14,091,688...14,118,084
JBrowse link
G SLC4A1 solute carrier family 4 member 1 (Diego blood group) involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:18698006) Ensembl
MGI
PMID:18698006 GO_REF:0000107 NCBI chr17:44,248,390...44,268,135
Ensembl chr17:44,248,390...44,268,141
JBrowse link
negative regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HPCA hippocalcin ISO RGD PMID:15336960 RGD:9686438 NCBI chr 1:32,885,996...32,894,646
Ensembl chr 1:32,885,994...32,898,441
JBrowse link
negative regulation of mitochondrial ATP synthesis coupled proton transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP5IF1 ATP synthase inhibitory factor subunit 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:28,236,124...28,238,100
Ensembl chr 1:28,236,109...28,246,906
JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDOB aldolase, fructose-bisphosphate B involved_in IMP (PMID:35122041) UniProt PMID:35122041 NCBI chr 9:101,420,560...101,435,774
Ensembl chr 9:101,420,560...101,449,664
JBrowse link
G TP53 tumor protein p53 involved_in IMP (PMID:21336310) CACAO PMID:21336310 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19654
    metabolic process 12453
      small molecule metabolic process 1982
        negative regulation of small molecule metabolic process 141
          negative regulation of nucleotide metabolic process 34
            negative regulation of purine nucleotide metabolic process 33
              negative regulation of ATP metabolic process + 30
              negative regulation of NAD metabolic process + 0
              negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
              negative regulation of pentose-phosphate shunt 2
              negative regulation of purine nucleotide biosynthetic process + 6
              negative regulation of purine nucleotide catabolic process + 23
              negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA 0
Path 2
Term Annotations click to browse term
  biological_process 19654
    metabolic process 12453
      cellular metabolic process 10633
        phosphorus metabolic process 1985
          phosphate-containing compound metabolic process 1953
            nucleoside phosphate metabolic process 669
              nucleotide metabolic process 663
                regulation of nucleotide metabolic process 109
                  negative regulation of nucleotide metabolic process 34
                    negative regulation of purine nucleotide metabolic process 33
                      negative regulation of ATP metabolic process + 30
                      negative regulation of NAD metabolic process + 0
                      negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
                      negative regulation of pentose-phosphate shunt 2
                      negative regulation of purine nucleotide biosynthetic process + 6
                      negative regulation of purine nucleotide catabolic process + 23
                      negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA 0
paths to the root