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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of purine nucleotide metabolic process
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Accession:GO:1900543 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process.
Synonyms:exact_synonym: down regulation of purine nucleotide metabolic process;   down regulation of purine nucleotide metabolism;   downregulation of purine nucleotide metabolic process;   downregulation of purine nucleotide metabolism;   negative regulation of purine nucleotide metabolism
 narrow_synonym: down regulation of purine metabolic process;   down regulation of purine metabolism;   downregulation of purine metabolic process;   downregulation of purine metabolism;   inhibition of purine metabolic process;   inhibition of purine metabolism;   inhibition of purine nucleotide metabolic process;   inhibition of purine nucleotide metabolism;   negative regulation of purine metabolic process;   negative regulation of purine metabolism


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negative regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 ISO RGD PMID:21325440 RGD:9685453 NCBI chr 9:88,921,826...89,034,418
Ensembl chr 9:88,922,007...89,032,880
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in ISO (PMID:24289924) ParkinsonsUK-UCL PMID:24289924 NCBI chr25:3,350,798...3,405,040 JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr25:3,350,821...3,388,826 JBrowse link
G PID1 phosphotyrosine interaction domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:115,012,225...115,268,843
Ensembl chr10:115,012,168...115,268,884
JBrowse link
negative regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FIS1 fission, mitochondrial 1 involved_in ISO (PMID:32521232) ARUK-UCL PMID:32521232 NCBI chr28:11,934,848...11,940,230
Ensembl chr28:11,934,821...11,941,901
JBrowse link
G TSPO translocator protein involved_in ISO (MGI:5689082|PMID:25470454) ParkinsonsUK-UCL PMID:25470454 MGI:5689082 NCBI chr19:25,678,602...25,690,556
Ensembl chr19:25,686,981...25,690,768
JBrowse link
negative regulation of glycolytic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 involved_in ISO (MGI:3759354|PMID:17828264) UniProt PMID:17828264 MGI:3759354 NCBI chr 1:7,708,595...7,724,634
Ensembl chr 1:7,705,725...7,724,589
JBrowse link
G CBFA2T3 CBFA2/RUNX1 partner transcriptional co-repressor 3 involved_in ISO (PMID:23840896) UniProt PMID:23840896 NCBI chr 5:74,260,516...74,361,268
Ensembl chr 5:74,263,375...74,289,875
JBrowse link
G DDIT4 DNA damage inducible transcript 4 acts_upstream_of_or_within ISO (PMID:20176937) MGI PMID:20176937 NCBI chr 9:59,033,058...59,035,157
Ensembl chr 9:59,032,755...59,035,241
JBrowse link
G FBP1 fructose-bisphosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:108,452,856...108,484,052
Ensembl chr12:108,453,156...108,483,775
JBrowse link
G FLCN folliculin involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:16,245,840...16,271,465
Ensembl chr16:16,245,715...16,267,698
JBrowse link
G GIT1 GIT ArfGAP 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:23,313,629...23,329,665
Ensembl chr16:23,315,439...23,329,469
JBrowse link
G HDAC4 histone deacetylase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:125,098,375...125,450,524
Ensembl chr10:125,098,366...125,403,227
JBrowse link
G IER3 immediate early response 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19096392) Ensembl
MGI
PMID:19096392 GO_REF:0000107 NCBI chr17:41,712,539...41,713,895
Ensembl chr17:41,712,528...41,714,126
JBrowse link
G LOC103223491 peroxisome proliferator-activated receptor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:28,614,892...28,709,272
Ensembl chr19:28,615,413...28,708,763
JBrowse link
G MYOG myogenin ISO RGD PMID:10225962 RGD:9686132 NCBI chr25:26,264,872...26,269,652
Ensembl chr25:26,266,717...26,268,867
JBrowse link
G NCOR1 nuclear receptor corepressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:15,442,315...15,629,411
Ensembl chr16:15,462,640...15,628,512
JBrowse link
G NUPR1 nuclear protein 1, transcriptional regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:26,382,125...26,385,605
Ensembl chr 5:26,382,132...26,385,348
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha involved_in ISO (PMID:19955185) BHF-UCL PMID:19955185
G PPARGC1A PPARG coactivator 1 alpha ISO RGD PMID:22343369 RGD:7242186 NCBI chr27:25,882,385...26,563,530
Ensembl chr27:26,465,499...26,564,582
JBrowse link
G SIK2 salt inducible kinase 2 involved_in ISO (PMID:21084751) MGI PMID:21084751 NCBI chr 1:102,944,171...103,070,973
Ensembl chr 1:102,944,281...103,068,823
JBrowse link
G SIRT6 sirtuin 6 involved_in ISO (MGI:4881401|PMID:20141841), (MGI:5619441|PMID:23217706)
(PMID:26456828)
CACAO
UniProt
PMID:20141841 PMID:23217706 PMID:26456828 MGI:4881401 MGI:5619441 NCBI chr 6:3,924,230...3,932,583
Ensembl chr 6:3,924,230...3,932,590
JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22891351) Ensembl
MGI
PMID:22891351 GO_REF:0000107 NCBI chr16:63,877,884...63,957,894
Ensembl chr16:63,922,862...63,957,984
JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:20935145) Ensembl
MGI
PMID:20935145 GO_REF:0000107 NCBI chr11:4,354,911...4,381,762
Ensembl chr11:4,355,053...4,381,273
JBrowse link
G TRIM63 tripartite motif containing 63 involved_in ISO (PMID:34244144) FlyBase PMID:34244144 NCBI chr20:106,676,299...106,714,394
Ensembl chr20:106,703,949...106,716,656
JBrowse link
negative regulation of glycolytic process through fructose-6-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:51,015,810...51,077,444
Ensembl chr  X:51,016,318...51,071,977
JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha involved_in ISO (PMID:32192773) MGI PMID:32192773 NCBI chr23:36,999,110...37,028,916
Ensembl chr23:36,997,078...37,029,280
JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in ISO (PMID:16155866)
(PMID:23292513)
MGI PMID:16155866 PMID:23292513 NCBI chr 6:12,743,752...12,759,155 JBrowse link
G SLC4A1 solute carrier family 4 member 1 (Diego blood group) acts_upstream_of_or_within ISO (PMID:18698006) MGI PMID:18698006 NCBI chr16:62,126,370...62,146,192
Ensembl chr16:62,131,709...62,146,182
JBrowse link
negative regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HPCA hippocalcin ISO RGD PMID:15336960 RGD:9686438 NCBI chr20:99,974,952...99,983,194
Ensembl chr20:99,975,742...99,980,728
JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDOB aldolase, fructose-bisphosphate B involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:37,993,367...38,021,693
Ensembl chr12:38,007,265...38,021,258
JBrowse link
G TP53 tumor protein p53 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16523
    metabolic process 10278
      small molecule metabolic process 1635
        negative regulation of small molecule metabolic process 109
          negative regulation of nucleotide metabolic process 33
            negative regulation of purine nucleotide metabolic process 32
              negative regulation of ATP metabolic process + 29
              negative regulation of NAD metabolic process + 0
              negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
              negative regulation of pentose-phosphate shunt 2
              negative regulation of purine nucleotide biosynthetic process + 5
              negative regulation of purine nucleotide catabolic process + 23
              negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA 0
Path 2
Term Annotations click to browse term
  biological_process 16523
    metabolic process 10278
      cellular metabolic process 8506
        phosphorus metabolic process 1742
          phosphate-containing compound metabolic process 1714
            nucleoside phosphate metabolic process 542
              nucleotide metabolic process 534
                regulation of nucleotide metabolic process 100
                  negative regulation of nucleotide metabolic process 33
                    negative regulation of purine nucleotide metabolic process 32
                      negative regulation of ATP metabolic process + 29
                      negative regulation of NAD metabolic process + 0
                      negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
                      negative regulation of pentose-phosphate shunt 2
                      negative regulation of purine nucleotide biosynthetic process + 5
                      negative regulation of purine nucleotide catabolic process + 23
                      negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA 0
paths to the root