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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of purine nucleotide metabolic process
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Accession:GO:1900543 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process.
Synonyms:exact_synonym: down regulation of purine nucleotide metabolic process;   down regulation of purine nucleotide metabolism;   downregulation of purine nucleotide metabolic process;   downregulation of purine nucleotide metabolism;   negative regulation of purine nucleotide metabolism
 narrow_synonym: down regulation of purine metabolic process;   down regulation of purine metabolism;   downregulation of purine metabolic process;   downregulation of purine metabolism;   inhibition of purine metabolic process;   inhibition of purine metabolism;   inhibition of purine nucleotide metabolic process;   inhibition of purine nucleotide metabolism;   negative regulation of purine metabolic process;   negative regulation of purine metabolism



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negative regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 ISO RGD PMID:21325440 RGD:9685453 NCBI chr28:9,181,851...9,311,835
Ensembl chr28:9,211,050...9,323,939
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:38,503,072...38,542,556
Ensembl chr 7:38,503,067...38,542,127
JBrowse link
G PID1 phosphotyrosine interaction domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:41,424,307...41,649,736
Ensembl chr25:41,425,811...41,652,672
JBrowse link
negative regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FIS1 fission, mitochondrial 1 involved_in ISO (PMID:32521232) ARUK-UCL PMID:32521232 NCBI chr 6:8,642,014...8,645,812
Ensembl chr 6:8,642,039...8,648,851
JBrowse link
G TSPO translocator protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:22,388,498...22,399,329
Ensembl chr10:22,274,405...22,399,297
JBrowse link
negative regulation of glycolytic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:50,787,353...50,801,036
Ensembl chr18:50,787,353...50,801,197
JBrowse link
G CBFA2T3 CBFA2/RUNX1 partner transcriptional co-repressor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:64,432,291...64,518,905
Ensembl chr 5:64,431,843...64,519,528
JBrowse link
G DDIT4 DNA damage inducible transcript 4 acts_upstream_of_or_within ISO (PMID:20176937) MGI PMID:20176937 NCBI chr 4:22,916,718...22,918,893
Ensembl chr 4:22,916,096...22,964,035
JBrowse link
G FBP1 fructose-bisphosphatase 1 involved_in ISO (PMID:25043030)
(PMID:19881551)
CAFA
UniProt
PMID:19881551 PMID:25043030 NCBI chr 1:72,099,886...72,125,266
Ensembl chr 1:72,099,881...72,125,224
JBrowse link
G FLCN folliculin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:42,176,093...42,195,718
Ensembl chr 5:42,176,291...42,195,711
JBrowse link
G GIT1 GIT ArfGAP 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:43,676,707...43,686,566
Ensembl chr 9:43,677,899...43,693,177
JBrowse link
G HDAC4 histone deacetylase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:49,318,621...49,545,314
Ensembl chr25:49,317,349...49,453,478
JBrowse link
G IER3 immediate early response 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19096392) Ensembl
MGI
PMID:19096392 GO_REF:0000107 NCBI chr12:529,002...530,328
Ensembl chr12:529,339...530,232
JBrowse link
G MTCH2 mitochondrial carrier 2 acts_upstream_of_or_within ISO (PMID:26219591) MGI PMID:26219591 NCBI chr18:42,023,484...42,045,331
Ensembl chr18:42,023,511...42,044,060
JBrowse link
G MYOG myogenin ISO RGD PMID:10225962 RGD:9686132 NCBI chr 7:112,116...114,604
Ensembl chr 7:112,034...113,892
JBrowse link
G NCOR1 nuclear receptor corepressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:39,687,530...39,837,003
Ensembl chr 5:39,687,543...39,836,464
JBrowse link
G NUPR1 nuclear protein 1, transcriptional regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:18,222,367...18,224,015
Ensembl chr 6:18,222,515...18,224,014
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha involved_in ISO (PMID:19955185) BHF-UCL PMID:19955185 NCBI chr10:19,934,020...20,006,096
Ensembl chr10:19,934,165...20,006,146
JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO RGD PMID:22343369 RGD:7242186 NCBI chr 3:85,645,942...86,284,570
Ensembl chr 3:86,016,140...86,281,269
JBrowse link
G SIK2 salt inducible kinase 2 involved_in ISO (PMID:21084751) MGI PMID:21084751 NCBI chr 5:21,354,127...21,479,891
Ensembl chr 5:21,358,902...21,479,841
JBrowse link
G SIRT6 sirtuin 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:55,412,989...55,424,944
Ensembl chr20:55,412,646...55,424,944
JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22891351) Ensembl
MGI
PMID:22891351 GO_REF:0000107 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672
JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:20935145) Ensembl
MGI
PMID:20935145 GO_REF:0000107 NCBI chr27:40,521,751...40,549,304
Ensembl chr27:40,523,314...40,549,332
JBrowse link
G TRIM63 tripartite motif containing 63 involved_in ISO (PMID:34244144) FlyBase PMID:34244144 NCBI chr 2:73,841,868...73,918,371
Ensembl chr 2:73,888,689...73,909,414
JBrowse link
negative regulation of glycolytic process through fructose-6-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC119881800 serine/threonine-protein phosphatase 2A catalytic subunit involved_in IEA Ensembl GO_REF:0000107
G PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:46,617,522...46,691,375
Ensembl chr  X:46,613,847...46,691,038
JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:22,388,327...22,410,052
Ensembl chr11:22,385,257...22,410,052
JBrowse link
G PPP2CB protein phosphatase 2 catalytic subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:33,532,703...33,567,011
Ensembl chr16:33,532,958...33,566,640
JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:48,416,730...48,425,237
Ensembl chr20:48,409,045...48,426,669
JBrowse link
G SLC4A1 solute carrier family 4 member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:18698006) Ensembl
MGI
PMID:18698006 GO_REF:0000107 NCBI chr 9:19,142,884...19,159,449
Ensembl chr 9:19,146,480...19,157,915
JBrowse link
negative regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HPCA hippocalcin ISO RGD PMID:15336960 RGD:9686438 NCBI chr 2:68,464,631...68,473,661
Ensembl chr 2:68,465,280...68,473,310
JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDOB aldolase, fructose-bisphosphate B involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:58,150,621...58,166,266
Ensembl chr11:58,150,967...58,176,319
JBrowse link
G TP53 tumor protein p53 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17308
    metabolic process 10607
      small molecule metabolic process 1715
        negative regulation of small molecule metabolic process 120
          negative regulation of nucleotide metabolic process 34
            negative regulation of purine nucleotide metabolic process 33
              negative regulation of ATP metabolic process + 30
              negative regulation of NAD metabolic process + 0
              negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
              negative regulation of pentose-phosphate shunt 2
              negative regulation of purine nucleotide biosynthetic process + 4
              negative regulation of purine nucleotide catabolic process + 25
              negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA 0
Path 2
Term Annotations click to browse term
  biological_process 17308
    metabolic process 10607
      cellular metabolic process 8805
        phosphorus metabolic process 1816
          phosphate-containing compound metabolic process 1789
            nucleoside phosphate metabolic process 597
              nucleotide metabolic process 591
                regulation of nucleotide metabolic process 100
                  negative regulation of nucleotide metabolic process 34
                    negative regulation of purine nucleotide metabolic process 33
                      negative regulation of ATP metabolic process + 30
                      negative regulation of NAD metabolic process + 0
                      negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
                      negative regulation of pentose-phosphate shunt 2
                      negative regulation of purine nucleotide biosynthetic process + 4
                      negative regulation of purine nucleotide catabolic process + 25
                      negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA 0
paths to the root