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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of purine nucleotide metabolic process
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Accession:GO:1900543 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process.
Synonyms:exact_synonym: down regulation of purine nucleotide metabolic process;   down regulation of purine nucleotide metabolism;   downregulation of purine nucleotide metabolic process;   downregulation of purine nucleotide metabolism;   negative regulation of purine nucleotide metabolism
 narrow_synonym: down regulation of purine metabolic process;   down regulation of purine metabolism;   downregulation of purine metabolic process;   downregulation of purine metabolism;   inhibition of purine metabolic process;   inhibition of purine metabolism;   inhibition of purine nucleotide metabolic process;   inhibition of purine nucleotide metabolism;   negative regulation of purine metabolic process;   negative regulation of purine metabolism


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negative regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 ISO RGD PMID:21325440 RGD:9685453 NCBI chrNW_004955507:2,035,918...2,141,327
Ensembl chrNW_004955507:2,036,050...2,137,377
JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 involved_in ISO (PMID:24289924) ParkinsonsUK-UCL PMID:24289924 NCBI chrNW_004955489:520,875...557,609
Ensembl chrNW_004955489:520,875...557,615
JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 involved_in ISO (PMID:20165904) BHF-UCL PMID:20165904 NCBI chrNW_004955453:5,680,418...5,913,236
Ensembl chrNW_004955453:5,680,211...5,911,589
JBrowse link
negative regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fis1 fission, mitochondrial 1 involved_in ISO (PMID:32521232) ARUK-UCL PMID:32521232 NCBI chrNW_004955456:16,057,158...16,060,623
Ensembl chrNW_004955456:16,038,221...16,060,623
JBrowse link
G Tspo translocator protein involved_in ISO (MGI:5689082|PMID:25470454) ParkinsonsUK-UCL PMID:25470454 MGI:5689082 NCBI chrNW_004955413:28,309,105...28,315,075
Ensembl chrNW_004955413:28,308,658...28,315,075
JBrowse link
negative regulation of glycolytic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in ISO (MGI:3759354|PMID:17828264) UniProt PMID:17828264 MGI:3759354 NCBI chrNW_004955422:18,799,372...18,812,458
Ensembl chrNW_004955422:18,799,372...18,812,711
JBrowse link
G Cbfa2t3 CBFA2/RUNX1 partner transcriptional co-repressor 3 involved_in ISO (PMID:23840896) UniProt PMID:23840896 NCBI chrNW_004955541:2,724,369...2,777,540
Ensembl chrNW_004955541:2,724,312...2,777,592
JBrowse link
G Ddit4 DNA damage inducible transcript 4 acts_upstream_of_or_within ISO (PMID:20176937) MGI PMID:20176937 NCBI chrNW_004955437:19,322,407...19,324,562
Ensembl chrNW_004955437:19,322,407...19,324,562
JBrowse link
G Fbp1 fructose-bisphosphatase 1 involved_in ISO (PMID:19881551)
(PMID:25043030)
UniProt
CAFA
PMID:19881551 PMID:25043030 NCBI chrNW_004955422:21,537,337...21,569,174
Ensembl chrNW_004955422:21,536,667...21,569,433
JBrowse link
G Flcn folliculin involved_in ISO (PMID:34381247) UniProt PMID:34381247 NCBI chrNW_004955577:672,774...694,140
Ensembl chrNW_004955577:672,410...694,140
JBrowse link
G Git1 GIT ArfGAP 1 involved_in ISO (MGI:6478067|PMID:32460388) UniProt PMID:32460388 MGI:6478067 NCBI chrNW_004955481:3,671,728...3,681,279
Ensembl chrNW_004955481:3,670,111...3,685,051
JBrowse link
G Hdac4 histone deacetylase 4 involved_in ISO (MGI:4365327|PMID:19109424) BHF-UCL PMID:19109424 MGI:4365327 NCBI chrNW_004955542:1,629,691...1,886,160
Ensembl chrNW_004955542:1,629,691...1,886,210
JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within ISO (PMID:19096392) MGI PMID:19096392 NCBI chrNW_004955583:730,353...731,301
Ensembl chrNW_004955583:730,289...731,260
JBrowse link
G Mtch2 mitochondrial carrier 2 acts_upstream_of_or_within ISO (PMID:26219591) MGI PMID:26219591 NCBI chrNW_004955422:672,301...690,989
Ensembl chrNW_004955422:672,301...690,989
JBrowse link
G Myog myogenin ISO RGD PMID:10225962 RGD:9686132 NCBI chrNW_004955406:39,099,044...39,102,479
Ensembl chrNW_004955406:39,099,716...39,102,501
JBrowse link
G Ncor1 nuclear receptor corepressor 1 involved_in ISO (PMID:19955185) BHF-UCL PMID:19955185 NCBI chrNW_004955467:1,408,292...1,568,539
Ensembl chrNW_004955467:1,409,281...1,546,842
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator involved_in ISO (PMID:30451898) UniProt PMID:30451898 NCBI chrNW_004955493:6,746,380...6,747,763
Ensembl chrNW_004955493:6,746,380...6,747,763
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha involved_in ISO (PMID:19955185) BHF-UCL PMID:19955185 NCBI chrNW_004955413:30,306,563...30,366,245
Ensembl chrNW_004955413:30,307,219...30,359,500
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha ISO RGD PMID:22343369 RGD:7242186 NCBI chrNW_004955480:543,397...1,188,376
Ensembl chrNW_004955480:1,078,322...1,188,435
JBrowse link
G Sik2 salt inducible kinase 2 involved_in ISO (PMID:21084751) MGI PMID:21084751 NCBI chrNW_004955412:13,342,032...13,458,076
Ensembl chrNW_004955412:13,342,032...13,457,563
JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (MGI:4881401|PMID:20141841), (MGI:5619441|PMID:23217706)
(PMID:26456828)
CACAO
UniProt
PMID:20141841 PMID:23217706 PMID:26456828 MGI:4881401 MGI:5619441 NCBI chrNW_004955495:4,641,883...4,650,518
Ensembl chrNW_004955495:4,644,023...4,650,083
JBrowse link
G Stat3 signal transducer and activator of transcription 3 acts_upstream_of_or_within ISO (PMID:22891351) MGI PMID:22891351 NCBI chrNW_004955451:16,320,326...16,348,505
Ensembl chrNW_004955451:16,319,904...16,357,687
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within ISO (PMID:20935145) MGI PMID:20935145 NCBI chrNW_004955413:2,129,719...2,153,873
Ensembl chrNW_004955413:2,129,678...2,154,380
JBrowse link
G Trim63 tripartite motif containing 63 involved_in ISO (PMID:34244144) FlyBase PMID:34244144 NCBI chrNW_004955452:5,517,969...5,531,490
Ensembl chrNW_004955452:5,520,269...5,531,975
JBrowse link
negative regulation of glycolytic process through fructose-6-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 involved_in ISO (PMID:16155866)
(PMID:15331593)
MGI PMID:15331593 PMID:16155866 NCBI chrNW_004955475:2,279,390...2,343,881
Ensembl chrNW_004955475:2,279,390...2,342,750
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha involved_in ISO (PMID:32192773) MGI PMID:32192773 NCBI chrNW_004955408:5,435,117...5,460,361
Ensembl chrNW_004955408:5,433,268...5,460,361
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in ISO (PMID:16155866)
(PMID:23292513)
MGI PMID:16155866 PMID:23292513 NCBI chrNW_004955415:32,794,172...32,807,944
Ensembl chrNW_004955415:32,793,718...32,812,930
JBrowse link
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) acts_upstream_of_or_within ISO (PMID:18698006) MGI PMID:18698006 NCBI chrNW_004955451:17,318,600...17,330,943
Ensembl chrNW_004955451:17,315,024...17,328,103
JBrowse link
negative regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hpca hippocalcin ISO RGD PMID:15336960 RGD:9686438 NCBI chrNW_004955452:11,142,282...11,150,798
Ensembl chrNW_004955452:11,140,373...11,154,261
JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldob aldolase, fructose-bisphosphate B involved_in ISO (PMID:35122041) UniProt PMID:35122041 NCBI chrNW_004955419:24,377,427...24,389,909
Ensembl chrNW_004955419:24,377,427...24,389,909
JBrowse link
G Tp53 tumor protein p53 involved_in ISO (PMID:21336310) CACAO PMID:21336310 NCBI chrNW_004955467:9,241,391...9,256,716
Ensembl chrNW_004955467:9,252,130...9,255,928
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12383
    metabolic process 7507
      small molecule metabolic process 1290
        negative regulation of small molecule metabolic process 107
          negative regulation of nucleotide metabolic process 32
            negative regulation of purine nucleotide metabolic process 31
              negative regulation of ATP metabolic process + 28
              negative regulation of NAD metabolic process + 0
              negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
              negative regulation of pentose-phosphate shunt 2
              negative regulation of purine nucleotide biosynthetic process + 4
              negative regulation of purine nucleotide catabolic process + 23
              negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA 0
Path 2
Term Annotations click to browse term
  biological_process 12383
    metabolic process 7507
      cellular metabolic process 6314
        phosphorus metabolic process 1484
          phosphate-containing compound metabolic process 1461
            nucleoside phosphate metabolic process 417
              nucleotide metabolic process 412
                regulation of nucleotide metabolic process 97
                  negative regulation of nucleotide metabolic process 32
                    negative regulation of purine nucleotide metabolic process 31
                      negative regulation of ATP metabolic process + 28
                      negative regulation of NAD metabolic process + 0
                      negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
                      negative regulation of pentose-phosphate shunt 2
                      negative regulation of purine nucleotide biosynthetic process + 4
                      negative regulation of purine nucleotide catabolic process + 23
                      negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA 0
paths to the root