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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of purine nucleotide metabolic process
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Accession:GO:1900543 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process.
Synonyms:exact_synonym: down regulation of purine nucleotide metabolic process;   down regulation of purine nucleotide metabolism;   downregulation of purine nucleotide metabolic process;   downregulation of purine nucleotide metabolism;   negative regulation of purine nucleotide metabolism
 narrow_synonym: down regulation of purine metabolic process;   down regulation of purine metabolism;   downregulation of purine metabolic process;   downregulation of purine metabolism;   inhibition of purine metabolic process;   inhibition of purine metabolism;   inhibition of purine nucleotide metabolic process;   inhibition of purine nucleotide metabolism;   negative regulation of purine metabolic process;   negative regulation of purine metabolism



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negative regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 IMP RGD PMID:21325440 RGD:9685453 NCBI chr 1:239,425,515...239,552,323
Ensembl chr 1:239,425,430...239,552,317
JBrowse link
G Mir675 microRNA 675 acts_upstream_of ISO (PMID:31574452) RGD PMID:31574452 NCBI chr 1:197,732,275...197,732,358
Ensembl chr 1:197,732,275...197,732,358
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in ISO (PMID:24289924) RGD PMID:24289924 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 involved_in ISO (PMID:20165904) RGD PMID:20165904 NCBI chr 9:85,284,335...85,503,035
Ensembl chr 9:85,284,335...85,503,044
JBrowse link
negative regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fis1 fission, mitochondrial 1 involved_in ISO
IEA
(PMID:32521232)
GO_REF:0000107
RGD
Ensembl
PMID:32521232 GO_REF:0000107 NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377
JBrowse link
G Tspo translocator protein involved_in ISO (MGI:5689082|PMID:25470454) RGD PMID:25470454 MGI:5689082 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
JBrowse link
negative regulation of glycolytic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in ISO (MGI:3759354|PMID:17828264) RGD PMID:17828264 MGI:3759354 NCBI chr 1:202,159,081...202,175,012
Ensembl chr 1:202,159,082...202,175,012
JBrowse link
G Cbfa2t3 CBFA2/RUNX1 partner transcriptional co-repressor 3 involved_in ISO (PMID:23840896) RGD PMID:23840896 NCBI chr19:50,679,897...50,750,028
Ensembl chr19:50,680,729...50,749,610
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:4440406|PMID:20176937)
Ensembl
RGD
PMID:20176937 GO_REF:0000107 MGI:4440406 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Fbp1 fructose-bisphosphatase 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:19881551), (PMID:25043030)
UniProt
Ensembl
RGD
PMID:19881551 PMID:25043030 GO_REF:0000024 GO_REF:0000107 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071
JBrowse link
G Flcn folliculin involved_in ISO (PMID:34381247) RGD PMID:34381247 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
G Git1 GIT ArfGAP 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:6478067|PMID:32460388)
UniProt
Ensembl
RGD
PMID:32460388 GO_REF:0000024 GO_REF:0000107 MGI:6478067 NCBI chr10:62,342,082...62,356,379
Ensembl chr10:62,342,299...62,356,373
JBrowse link
G Hdac4 histone deacetylase 4 involved_in ISO
IEA
(MGI:4365327|PMID:19109424)
GO_REF:0000107
RGD
Ensembl
PMID:19109424 GO_REF:0000107 MGI:4365327 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164
JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within ISO MGI:3773690 (MGI:4437986|PMID:19096392) RGD PMID:19096392 MGI:4437986 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Mtch2 mitochondrial carrier 2 acts_upstream_of_or_within ISO MGI:2449949|MGI:5566664 (MGI:5662300|PMID:26219591) RGD PMID:26219591 MGI:5662300 NCBI chr 3:76,830,549...76,850,189
Ensembl chr 3:76,830,413...76,850,189
JBrowse link
G Myog myogenin IDA RGD PMID:10225962 RGD:9686132 NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 involved_in ISO
IEA
(PMID:19955185)
GO_REF:0000107
RGD
Ensembl
PMID:19955185 GO_REF:0000107 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator involved_in ISO
ISS
(PMID:30451898)
GO_REF:0000024
RGD
UniProt
PMID:30451898 GO_REF:0000024 NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha involved_in ISO (PMID:19955185) RGD PMID:19955185 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IMP RGD PMID:22343369 RGD:7242186 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Sik2 salt-inducible kinase 2 involved_in ISO (MGI:5000207|PMID:21084751) RGD PMID:21084751 MGI:5000207 NCBI chr 8:51,225,543...51,325,343
Ensembl chr 8:51,225,543...51,325,415
JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (MGI:4881401|PMID:20141841), (MGI:5619441|PMID:23217706)
(PMID:26456828)
RGD PMID:20141841 PMID:23217706 PMID:26456828 MGI:4881401 MGI:5619441 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914
JBrowse link
G Stat3 signal transducer and activator of transcription 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5441121|PMID:22891351)
GO_REF:0000107
RGD
Ensembl
PMID:22891351 GO_REF:0000107 MGI:5441121 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within ISO (MGI:4867601|PMID:20935145) RGD PMID:20935145 MGI:4867601 NCBI chr 4:159,927,136...159,946,077
Ensembl chr 4:159,927,139...159,946,029
JBrowse link
G Trim63 tripartite motif containing 63 involved_in ISO (PMID:34244144) RGD PMID:34244144 NCBI chr 5:146,533,492...146,547,332
Ensembl chr 5:146,533,507...146,547,322
JBrowse link
negative regulation of glycolytic process through fructose-6-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 involved_in ISO MGI:97592 (MGI:3512852|PMID:15331593), (MGI:3609451|PMID:16155866) RGD PMID:15331593 PMID:16155866 MGI:3512852 MGI:3609451 NCBI chr  X:19,508,522...19,562,165
Ensembl chr  X:19,508,546...19,562,182
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha involved_in ISO MGI:4950915 (MGI:6447406|PMID:32192773) RGD PMID:32192773 MGI:6447406 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in ISO
IEA
MGI:3610390 (MGI:3609451|PMID:16155866), (MGI:6209935|PMID:23292513)
GO_REF:0000107
RGD
Ensembl
PMID:16155866 PMID:23292513 GO_REF:0000107 MGI:3609451 MGI:6209935 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3820439|PMID:18698006)
GO_REF:0000107
RGD
Ensembl
PMID:18698006 GO_REF:0000107 MGI:3820439 NCBI chr10:87,306,865...87,323,132
Ensembl chr10:87,306,872...87,323,117
JBrowse link
negative regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hpca hippocalcin IDA RGD PMID:15336960 RGD:9686438 NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841
JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldob aldolase, fructose-bisphosphate B involved_in IEA
ISO
GO_REF:0000107
(PMID:35122041)
Ensembl
RGD
PMID:35122041 GO_REF:0000107 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116
JBrowse link
G Tp53 tumor protein p53 involved_in ISO
IEA
(PMID:21336310)
GO_REF:0000107
RGD
Ensembl
PMID:21336310 GO_REF:0000107 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20328
    metabolic process 11732
      negative regulation of metabolic process 3069
        negative regulation of small molecule metabolic process 126
          negative regulation of nucleotide metabolic process 33
            negative regulation of purine nucleotide metabolic process 32
              negative regulation of ATP metabolic process + 29
              negative regulation of NAD metabolic process + 0
              negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
              negative regulation of pentose-phosphate shunt 2
              negative regulation of purine nucleotide biosynthetic process + 5
              negative regulation of purine nucleotide catabolic process + 23
              negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA 0
Path 2
Term Annotations click to browse term
  biological_process 20328
    metabolic process 11732
      cellular metabolic process 10286
        cellular aromatic compound metabolic process 5963
          nucleobase-containing compound metabolic process 5720
            nucleobase-containing small molecule metabolic process 710
              nucleoside phosphate metabolic process 636
                nucleotide metabolic process 626
                  regulation of nucleotide metabolic process 99
                    negative regulation of nucleotide metabolic process 33
                      negative regulation of purine nucleotide metabolic process 32
                        negative regulation of ATP metabolic process + 29
                        negative regulation of NAD metabolic process + 0
                        negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
                        negative regulation of pentose-phosphate shunt 2
                        negative regulation of purine nucleotide biosynthetic process + 5
                        negative regulation of purine nucleotide catabolic process + 23
                        negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA 0
paths to the root