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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of purine nucleotide metabolic process
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Accession:GO:1900543 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process.
Synonyms:exact_synonym: down regulation of purine nucleotide metabolic process;   down regulation of purine nucleotide metabolism;   downregulation of purine nucleotide metabolic process;   downregulation of purine nucleotide metabolism;   negative regulation of purine nucleotide metabolism
 narrow_synonym: down regulation of purine metabolic process;   down regulation of purine metabolism;   downregulation of purine metabolic process;   downregulation of purine metabolism;   inhibition of purine metabolic process;   inhibition of purine metabolism;   inhibition of purine nucleotide metabolic process;   inhibition of purine nucleotide metabolism;   negative regulation of purine metabolic process;   negative regulation of purine metabolism


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negative regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 IMP RGD PMID:21325440 RGD:9685453 NCBI chr 1:239,425,515...239,552,323
Ensembl chr 1:239,425,430...239,552,317 		JBrowse link
G Mir675 microRNA 675 acts_upstream_of ISO (PMID:31574452) RGD PMID:31574452 NCBI chr 1:197,732,275...197,732,358
Ensembl chr 1:197,732,275...197,732,358 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in ISO
IEA 		(PMID:24289924)
GO_REF:0000107 		RGD
Ensembl		 PMID:24289924 GO_REF:0000107 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 involved_in ISO
IEA 		(PMID:20165904)
GO_REF:0000107 		RGD
Ensembl		 PMID:20165904 GO_REF:0000107 NCBI chr 9:85,284,335...85,503,035
Ensembl chr 9:85,284,335...85,503,044 		JBrowse link
negative regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fis1 fission, mitochondrial 1 involved_in ISO
IEA 		(PMID:32521232)
GO_REF:0000107 		RGD
Ensembl		 PMID:32521232 GO_REF:0000107 NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377 		JBrowse link
G Tspo translocator protein involved_in ISO
IEA 		(PMID:25470454)
GO_REF:0000107 		RGD
Ensembl		 PMID:25470454 GO_REF:0000107 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450 		JBrowse link
negative regulation of glycolytic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in ISO
IEA 		(PMID:17828264)
GO_REF:0000107 		RGD
Ensembl		 PMID:17828264 GO_REF:0000107 NCBI chr 1:202,159,081...202,175,012
Ensembl chr 1:202,159,082...202,175,012 		JBrowse link
G Cbfa2t3 CBFA2/RUNX1 partner transcriptional co-repressor 3 involved_in ISO
IEA 		(PMID:23840896)
GO_REF:0000107 		RGD
Ensembl		 PMID:23840896 GO_REF:0000107 NCBI chr19:50,679,897...50,750,028
Ensembl chr19:50,680,729...50,749,610 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 acts_upstream_of_or_within ISO
IEA 		(PMID:20176937)
GO_REF:0000107 		RGD
Ensembl		 PMID:20176937 GO_REF:0000107 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Fbp1 fructose-bisphosphatase 1 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:19881551), (PMID:25043030) 		UniProt
Ensembl
RGD		 PMID:19881551 PMID:25043030 GO_REF:0000024 GO_REF:0000107 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071 		JBrowse link
G Flcn folliculin involved_in ISO
IEA 		(PMID:34381247)
GO_REF:0000107 		RGD
Ensembl		 PMID:34381247 GO_REF:0000107 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769 		JBrowse link
G Git1 GIT ArfGAP 1 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:32460388)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:32460388 GO_REF:0000024 GO_REF:0000107 NCBI chr10:62,342,082...62,356,379
Ensembl chr10:62,342,299...62,356,373 		JBrowse link
G Hdac4 histone deacetylase 4 involved_in IEA
ISO 		GO_REF:0000107
(PMID:19109424) 		Ensembl
RGD		 PMID:19109424 GO_REF:0000107 NCBI chr 9:99,950,972...100,200,994
Ensembl chr 9:92,507,611...92,750,164 		JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within ISO
IEA 		MGI:3773690 (PMID:19096392)
GO_REF:0000107 		RGD
Ensembl		 PMID:19096392 GO_REF:0000107 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583 		JBrowse link
G Mtch2 mitochondrial carrier 2 acts_upstream_of_or_within ISO MGI:2449949|MGI:5566664 (PMID:26219591) RGD PMID:26219591 NCBI chr 3:76,830,549...76,850,189
Ensembl chr 3:76,830,413...76,850,189 		JBrowse link
G Myog myogenin IDA RGD PMID:10225962 RGD:9686132 NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039 		JBrowse link
G Ncor1 nuclear receptor co-repressor 1 involved_in ISO (PMID:19955185) RGD PMID:19955185 NCBI chr10:47,498,852...47,641,612
Ensembl chr10:46,999,536...47,141,032 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator involved_in ISO
IEA
ISS 		(PMID:30451898)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:30451898 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha involved_in ISO
IEA 		(PMID:19955185)
GO_REF:0000107 		RGD
Ensembl		 PMID:19955185 GO_REF:0000107 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IMP RGD PMID:22343369 RGD:7242186 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Sik2 salt-inducible kinase 2 involved_in ISO (PMID:21084751) RGD PMID:21084751 NCBI chr 8:51,225,543...51,325,343
Ensembl chr 8:51,225,543...51,325,415 		JBrowse link
G Sirt6 sirtuin 6 involved_in ISO
IEA 		(PMID:26456828)
GO_REF:0000107
(PMID:20141841), (PMID:23217706) 		RGD
Ensembl		 PMID:20141841 PMID:23217706 PMID:26456828 GO_REF:0000107 NCBI chr 7:8,733,056...8,738,543
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 acts_upstream_of_or_within ISO
IEA 		(PMID:22891351)
GO_REF:0000107 		RGD
Ensembl		 PMID:22891351 GO_REF:0000107 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within
involved_in 		ISO
IEA
IBA 		(PMID:20935145)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:20935145 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:159,927,136...159,946,077
Ensembl chr 4:159,927,139...159,946,029
Ensembl chr 6:159,927,139...159,946,029 		JBrowse link
G Trim63 tripartite motif containing 63 involved_in ISO
IEA 		(PMID:34244144)
GO_REF:0000107 		RGD
Ensembl		 PMID:34244144 GO_REF:0000107 NCBI chr 5:151,817,209...151,831,026
Ensembl chr 5:146,533,507...146,547,322 		JBrowse link
negative regulation of glycolytic process through fructose-6-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpi glucose-6-phosphate isomerase acts_upstream_of_or_within ISO MGI:97592 (PMID:16155866) RGD PMID:16155866 NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086 		JBrowse link
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 involved_in ISO MGI:97592 (PMID:15331593), (PMID:16155866) RGD PMID:15331593 PMID:16155866 NCBI chr  X:19,508,522...19,562,165
Ensembl chr  X:19,508,546...19,562,182 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha involved_in ISO MGI:4950915 (PMID:32192773) RGD PMID:32192773 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in IEA
ISO 		GO_REF:0000107
MGI:3610390 (PMID:16155866), (PMID:23292513) 		Ensembl
RGD		 PMID:16155866 PMID:23292513 GO_REF:0000107 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) acts_upstream_of_or_within ISO
IEA 		(PMID:18698006)
GO_REF:0000107 		RGD
Ensembl		 PMID:18698006 GO_REF:0000107 NCBI chr10:87,306,865...87,323,132
Ensembl chr10:87,306,872...87,323,117 		JBrowse link
negative regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hpca hippocalcin IDA RGD PMID:15336960 RGD:9686438 NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841 		JBrowse link
G Rd3 RD3 regulator of GUCY2D involved_in ISO (PMID:21928830), (PMID:30559291)
(PMID:27471269) 		RGD PMID:21928830 PMID:27471269 PMID:30559291 NCBI chr13:103,551,823...103,562,925
Ensembl chr13:103,552,857...103,562,622 		JBrowse link
negative regulation of mitochondrial ATP synthesis coupled proton transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668 		JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldob aldolase, fructose-bisphosphate B involved_in IEA
ISO 		GO_REF:0000107
(PMID:35122041) 		Ensembl
RGD		 PMID:35122041 GO_REF:0000107 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116 		JBrowse link
G Tp53 tumor protein p53 involved_in ISO
IEA 		(PMID:21336310)
GO_REF:0000107 		RGD
Ensembl		 PMID:21336310 GO_REF:0000107 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        purine-containing compound metabolic process 617
          purine nucleotide metabolic process 480
            negative regulation of purine nucleotide metabolic process 35
              negative regulation of ATP metabolic process + 31
              negative regulation of NAD metabolic process + 0
              negative regulation of pentose-phosphate shunt 2
              negative regulation of purine nucleotide biosynthetic process + 7
              negative regulation of purine nucleotide catabolic process + 24
Path 2
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        primary metabolic process 10727
          nucleobase-containing compound metabolic process 5900
            nucleobase-containing small molecule metabolic process 730
              nucleoside phosphate metabolic process 699
                nucleotide metabolic process 540
                  purine nucleotide metabolic process 480
                    regulation of purine nucleotide metabolic process 103
                      negative regulation of purine nucleotide metabolic process 35
                        negative regulation of ATP metabolic process + 31
                        negative regulation of NAD metabolic process + 0
                        negative regulation of pentose-phosphate shunt 2
                        negative regulation of purine nucleotide biosynthetic process + 7
                        negative regulation of purine nucleotide catabolic process + 24
paths to the root