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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of purine nucleotide metabolic process
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Accession:GO:1900543 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process.
Synonyms:exact_synonym: down regulation of purine nucleotide metabolic process;   down regulation of purine nucleotide metabolism;   downregulation of purine nucleotide metabolic process;   downregulation of purine nucleotide metabolism;   negative regulation of purine nucleotide metabolism
 narrow_synonym: down regulation of purine metabolic process;   down regulation of purine metabolism;   downregulation of purine metabolic process;   downregulation of purine metabolism;   inhibition of purine metabolic process;   inhibition of purine metabolism;   inhibition of purine nucleotide metabolic process;   inhibition of purine nucleotide metabolism;   negative regulation of purine metabolic process;   negative regulation of purine metabolism


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negative regulation of ATP biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 IMP RGD PMID:21325440 RGD:9685453 NCBI chr 1:259,692,020...259,818,922
Ensembl chr 1:259,739,955...259,819,494
JBrowse link
G Flcn folliculin ISO
ISS
(MGI:MGI:5463828|PMID:23150719)
GO_REF:0000024
RGD
UniProt
PMID:23150719 GO_REF:0000024, MGI:MGI:5463828 NCBI chr10:46,153,185...46,172,331
Ensembl chr10:46,153,188...46,172,309
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO (PMID:24289924) RGD PMID:24289924 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 ISO (PMID:20165904) RGD PMID:20165904 NCBI chr 9:91,667,748...91,683,468
Ensembl chr 9:91,665,986...91,882,927
JBrowse link
negative regulation of glycolytic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 ISO (MGI:MGI:3759354|PMID:17828264) RGD PMID:17828264 MGI:MGI:3759354 NCBI chr 1:220,120,532...220,136,460
Ensembl chr 1:220,120,533...220,136,470
JBrowse link
G Cbfa2t3 CBFA2/RUNX1 partner transcriptional co-repressor 3 ISO (PMID:23840896) RGD PMID:23840896 NCBI chr19:55,438,409...55,510,652
Ensembl chr19:55,441,572...55,510,460
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 ISO
IEA
(MGI:MGI:4440406|PMID:20176937)
GO_REF:0000107
RGD
Ensembl
PMID:20176937 GO_REF:0000107, MGI:MGI:4440406 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Fbp1 fructose-bisphosphatase 1 IEA
ISO
ISS
GO_REF:0000107
(PMID:19881551), (PMID:25043030)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:19881551, PMID:25043030 GO_REF:0000024, GO_REF:0000107 NCBI chr17:396,175...417,480
Ensembl chr17:396,180...417,480
JBrowse link
G Hdac4 histone deacetylase 4 ISO (MGI:MGI:4365327|PMID:19109424) RGD PMID:19109424 MGI:MGI:4365327 NCBI chr 9:99,052,945...99,299,715
Ensembl chr 9:99,057,089...99,299,715
JBrowse link
G Ier3 immediate early response 3 ISO MGI:MGI:3773690 (MGI:MGI:4437986|PMID:19096392) RGD PMID:19096392 MGI:MGI:4437986 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
JBrowse link
G Mtch2 mitochondrial carrier 2 ISO MGI:MGI:2449949|MGI:MGI:5566664 (MGI:MGI:5662300|PMID:26219591) RGD PMID:26219591 MGI:MGI:5662300 NCBI chr 3:79,678,141...79,695,356
Ensembl chr 3:79,678,201...79,694,006
JBrowse link
G Myog myogenin IDA RGD PMID:10225962 RGD:9686132 NCBI chr13:51,126,459...51,129,048
Ensembl chr13:51,126,459...51,129,048
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 ISO
IEA
(PMID:19955185)
GO_REF:0000107
RGD
Ensembl
PMID:19955185 GO_REF:0000107 NCBI chr10:48,629,121...48,772,890
Ensembl chr10:48,629,121...48,772,890
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator ISS
ISO
GO_REF:0000024
(PMID:30451898)
UniProt
RGD
PMID:30451898 GO_REF:0000024 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO (PMID:19955185) RGD PMID:19955185 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IMP RGD PMID:22343369 RGD:7242186 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Sirt6 sirtuin 6 ISO (MGI:MGI:4881401|PMID:20141841), (MGI:MGI:5619441|PMID:23217706) RGD PMID:20141841, PMID:23217706 MGI:MGI:4881401, MGI:MGI:5619441 NCBI chr 7:10,937,622...10,943,048
Ensembl chr 7:10,937,599...10,943,063
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO (MGI:MGI:5441121|PMID:22891351) RGD PMID:22891351 MGI:MGI:5441121 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase ISO
IBA
(MGI:MGI:4867601|PMID:20935145)
PMID:21873635
RGD PMID:20935145, PMID:21873635 MGI:MGI:4867601, RGD:13792537 NCBI chr 4:159,635,145...159,654,108
Ensembl chr 4:159,635,153...159,654,063
JBrowse link
negative regulation of glycolytic process through fructose-6-phosphate term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) ISO
IEA
(MGI:MGI:3820439|PMID:18698006)
GO_REF:0000107
RGD
Ensembl
PMID:18698006 GO_REF:0000107, MGI:MGI:3820439 NCBI chr10:90,296,144...90,312,401
Ensembl chr10:90,296,141...90,312,386
JBrowse link
negative regulation of guanylate cyclase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hpca hippocalcin IDA RGD PMID:15336960 RGD:9686438 NCBI chr 5:147,295,124...147,305,757
Ensembl chr 5:147,294,820...147,303,346
JBrowse link
G Pdzd3 PDZ domain containing 3 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:48,577,905...48,582,353
Ensembl chr 8:48,577,952...48,582,353
JBrowse link
G Rd3 retinal degeneration 3, GUCY2D regulator ISO (PMID:21928830), (PMID:30559291)
(MGI:MGI:5810226|PMID:27471269)
RGD PMID:21928830, PMID:27471269, PMID:30559291 MGI:MGI:5810226 NCBI chr13:110,739,645...110,749,167
Ensembl chr13:110,743,098...110,748,365
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    metabolic process 12256
      negative regulation of metabolic process 3315
        negative regulation of small molecule metabolic process 106
          negative regulation of nucleotide metabolic process 24
            negative regulation of purine nucleotide metabolic process 23
              negative regulation of glycolytic process + 16
              negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
              negative regulation of purine nucleotide biosynthetic process + 7
              negative regulation of purine nucleotide catabolic process + 0
              negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA 0
Path 2
Term Annotations click to browse term
  biological_process 20017
    metabolic process 12256
      cellular metabolic process 11064
        cellular aromatic compound metabolic process 5708
          nucleobase-containing compound metabolic process 5483
            nucleobase-containing small molecule metabolic process 590
              nucleoside phosphate metabolic process 510
                nucleotide metabolic process 503
                  regulation of nucleotide metabolic process 88
                    negative regulation of nucleotide metabolic process 24
                      negative regulation of purine nucleotide metabolic process 23
                        negative regulation of glycolytic process + 16
                        negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway 0
                        negative regulation of purine nucleotide biosynthetic process + 7
                        negative regulation of purine nucleotide catabolic process + 0
                        negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.