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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of purine nucleotide metabolic process
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Accession:GO:1900542 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of purine nucleotide metabolic process.
Synonyms:exact_synonym: regulation of purine nucleotide metabolism
 narrow_synonym: regulation of purine metabolic process;   regulation of purine metabolism


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regulation of purine nucleotide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lacc1 laccase domain containing 1 involved_in ISO (MGI:6436442|PMID:31978345) RGD PMID:31978345 MGI:6436442 NCBI chr15:52,390,267...52,407,630
Ensembl chr15:52,395,183...52,407,545 		JBrowse link
negative regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 IMP RGD PMID:21325440 RGD:9685453 NCBI chr 1:239,425,515...239,552,323
Ensembl chr 1:239,425,430...239,552,317 		JBrowse link
G Flcn folliculin involved_in ISO
ISS		 (MGI:5463828|PMID:23150719)
GO_REF:0000024		 RGD
UniProt		 PMID:23150719 GO_REF:0000024 MGI:5463828 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769 		JBrowse link
G H19 H19 imprinted maternally expressed transcript acts_upstream_of ISO (PMID:31574452) RGD PMID:31574452 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134 		JBrowse link
G Mir675 microRNA 675 acts_upstream_of ISO (PMID:31574452) RGD PMID:31574452 NCBI chr 1:197,732,275...197,732,358
Ensembl chr 1:197,732,275...197,732,358 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in ISO (PMID:24289924) RGD PMID:24289924 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 involved_in ISO (PMID:20165904) RGD PMID:20165904 NCBI chr 9:85,284,335...85,503,035
Ensembl chr 9:85,284,335...85,503,044 		JBrowse link
negative regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fis1 fission, mitochondrial 1 involved_in ISO (PMID:32521232) RGD PMID:32521232 NCBI chr12:19,708,558...19,723,392
Ensembl chr12:19,708,558...19,723,377 		JBrowse link
G Tspo translocator protein involved_in ISO (MGI:5689082|PMID:25470454) RGD PMID:25470454 MGI:5689082 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450 		JBrowse link
negative regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hpca hippocalcin IDA RGD PMID:15336960 RGD:9686438 NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841 		JBrowse link
G Rd3 RD3 regulator of GUCY2D involved_in ISO (PMID:21928830), (PMID:30559291)
(MGI:5810226|PMID:27471269)		 RGD PMID:21928830 PMID:27471269 PMID:30559291 MGI:5810226 NCBI chr13:103,551,823...103,562,925
Ensembl chr13:103,552,857...103,562,622 		JBrowse link
negative regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tp53 tumor protein p53 involved_in ISO (PMID:21336310) RGD PMID:21336310 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
positive regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 IMP RGD PMID:31172217 RGD:329403053 NCBI chr13:77,747,752...77,833,952
Ensembl chr13:77,768,468...77,833,951 		JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in IMP PMID:23792689 CAFA PMID:23792689 RGD:12793033 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Eno1 enolase 1 involved_in ISO UniProtKB:Q01986 (PMID:15459207) RGD PMID:15459207 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336 		JBrowse link
G Hnf1a HNF1 homeobox A IMP RGD PMID:20841353 RGD:150540305 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104 		JBrowse link
G Il4 interleukin 4 involved_in ISO (MGI:6304699|PMID:29061364) RGD PMID:29061364 MGI:6304699 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 involved_in IMP
IGI		 PMID:15459207 CAFA PMID:15459207 PMID:15459207 RGD:12793039, RGD:12793039 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor IMP RGD PMID:22629444 RGD:7240532 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 IMP RGD PMID:26888427 RGD:11040458 NCBI chr 1:151,711,965...151,718,188
Ensembl chr 1:151,711,901...151,718,189 		JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 involved_in ISO (MGI:5306739|PMID:21080215) RGD PMID:21080215 MGI:5306739 NCBI chr 9:85,284,335...85,503,035
Ensembl chr 9:85,284,335...85,503,044 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha acts_upstream_of ISO (PMID:31574452) RGD PMID:31574452 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha involved_in ISS
ISO		 GO_REF:0000024
(MGI:5463828|PMID:23150719)		 UniProt
RGD		 PMID:23150719 GO_REF:0000024 MGI:5463828 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IMP RGD PMID:24096089 RGD:10413842 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:24747689) RGD PMID:24747689 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Slc25a12 solute carrier family 25 member 12 IMP RGD PMID:19764902 RGD:13628741 NCBI chr 3:56,098,080...56,192,188
Ensembl chr 3:56,097,269...56,192,100 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 IMP RGD PMID:23590160 RGD:8694322 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tafazzin tafazzin, phospholipid-lysophospholipid transacylase IMP RGD PMID:20348225 RGD:13432160 NCBI chr  X:152,065,539...152,076,178
Ensembl chr  X:152,065,609...152,074,001 		JBrowse link
G Tmsb4x thymosin beta 4, X-linked involved_in ISO (PMID:21106936) RGD PMID:21106936 NCBI chr  X:27,144,677...27,146,667
Ensembl chr  X:27,128,610...27,146,667 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:5906931|PMID:28802038) RGD PMID:28802038 MGI:5906931 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Vcp valosin-containing protein involved_in ISO (PMID:23498975) RGD PMID:23498975 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571 		JBrowse link
positive regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bend3 BEN domain containing 3 involved_in ISO (PMID:28977671) RGD PMID:28977671 NCBI chr20:46,980,246...47,017,059
Ensembl chr20:46,979,831...47,014,671 		JBrowse link
positive regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2B receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3773754 (MGI:3794903|PMID:18340377)		 Ensembl
RGD		 PMID:18340377 GO_REF:0000107 MGI:3794903 NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772 		JBrowse link
G Guca1a guanylate cyclase activator 1A involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:12545196 PMID:21873635 RGD:1599357, RGD:13792537 NCBI chr 9:13,587,695...13,598,566
Ensembl chr 9:13,588,525...13,598,565 		JBrowse link
G Nos1 nitric oxide synthase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Nos2 nitric oxide synthase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nos3 nitric oxide synthase 3 involved_in ISO
IBA
IEA		 (PMID:17502619)
PMID:21873635
GO_REF:0000107		 RGD
Ensembl		 PMID:17502619 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
positive regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tigar TP53 induced glycolysis regulatory phosphatase involved_in ISO (MGI:5574521|PMID:24872551) RGD PMID:24872551 MGI:5574521 NCBI chr 4:159,927,138...159,946,094
Ensembl chr 4:159,927,139...159,946,029 		JBrowse link
regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdk1 pyruvate dehydrogenase kinase 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5487511|PMID:22195962)		 Ensembl
RGD		 PMID:22195962 GO_REF:0000107 MGI:5487511 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038 		JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 involved_in ISO
ISS		 (MGI:5428826|PMID:22360721)
GO_REF:0000024		 RGD
UniProt		 PMID:22360721 GO_REF:0000024 MGI:5428826 NCBI chr10:79,972,550...79,987,074
Ensembl chr10:79,972,556...79,987,085 		JBrowse link
G Pdk3 pyruvate dehydrogenase kinase 3 involved_in ISO (PMID:22865452) RGD PMID:22865452 NCBI chr  X:58,477,471...58,553,932
Ensembl chr  X:58,486,554...58,553,557 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 involved_in ISO
ISS		 (PMID:21852536)
(MGI:3692363|PMID:16606348)
GO_REF:0000024		 RGD
UniProt		 PMID:16606348 PMID:21852536 GO_REF:0000024 MGI:3692363 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850 		JBrowse link
regulation of acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snca synuclein alpha acts_upstream_of_or_within ISO MGI:2389489 (MGI:3628986|PMID:16636270), (MGI:3629421|PMID:16734431) RGD PMID:16636270 PMID:16734431 MGI:3628986 MGI:3629421 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sphk2 sphingosine kinase 2 involved_in ISO (MGI:5641585|PMID:25637806) RGD PMID:25637806 MGI:5641585 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391 		JBrowse link
regulation of ATP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 involved_in ISO (PMID:24005319) RGD PMID:24005319 NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668 		JBrowse link
G Dnm1l dynamin 1-like involved_in ISO (MGI:4459561|PMID:20585624) RGD PMID:20585624 MGI:4459561 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482 		JBrowse link
regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Guca1a guanylate cyclase activator 1A acts_upstream_of_or_within ISO MGI:1194489 (MGI:3052899|PMID:15336959) RGD PMID:15336959 MGI:3052899 NCBI chr 9:13,587,695...13,598,566
Ensembl chr 9:13,588,525...13,598,565 		JBrowse link
G Guca1b guanylate cyclase activator 1B acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:102770 (MGI:3052899|PMID:15336959)
PMID:21873635		 RGD PMID:15336959 PMID:21873635 MGI:3052899, RGD:13792537 NCBI chr 9:13,599,619...13,607,455
Ensembl chr 9:13,599,619...13,607,455 		JBrowse link
regulation of mitochondrial ATP synthesis coupled proton transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Antkmt adenine nucleotide translocase lysine methyltransferase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:14,812,274...14,814,798
Ensembl chr10:14,812,269...14,814,193 		JBrowse link
G Atpsckmt ATP synthase c subunit lysine N-methyltransferase involved_in ISO
IBA
ISS		 (PMID:30530489)
(MGI:6277238|PMID:30530489)
PMID:21873635
GO_REF:0000024		 RGD
UniProt		 PMID:30530489 PMID:21873635 GO_REF:0000024 MGI:6277238, RGD:13792537 NCBI chr 2:82,603,086...82,618,325
Ensembl chr 2:82,603,009...82,618,308 		JBrowse link
G Dnajc30 DnaJ heat shock protein family (Hsp40) member C30 involved_in ISO (MGI:6245118|PMID:30318146) RGD PMID:30318146 MGI:6245118 NCBI chr12:21,628,323...21,629,389
Ensembl chr12:21,626,450...21,629,408 		JBrowse link
regulation of NAD metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Macroh2a1 macroH2A.1 histone involved_in ISS
ISO		 GO_REF:0000024
(MGI:6863428|PMID:28991266)		 UniProt
RGD		 PMID:28991266 GO_REF:0000024 MGI:6863428 NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072 		JBrowse link
regulation of NADP metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnf1a HNF1 homeobox A IMP RGD PMID:20841353 RGD:150540305 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104 		JBrowse link
G Me1 malic enzyme 1 involved_in ISO
IEA		 (PMID:23334421)
GO_REF:0000107		 RGD
Ensembl		 PMID:23334421 GO_REF:0000107 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304 		JBrowse link
G Me2 malic enzyme 2 involved_in ISO (PMID:23334421) RGD PMID:23334421 NCBI chr18:67,350,833...67,400,987
Ensembl chr18:67,355,795...67,400,987 		JBrowse link
regulation of pentose-phosphate shunt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 IDA RGD PMID:16234247 RGD:1625062 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687 		JBrowse link
G Pgam1 phosphoglycerate mutase 1 involved_in ISO (PMID:12189148) RGD PMID:12189148 NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452 		JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase involved_in ISO (PMID:25928429) RGD PMID:25928429 NCBI chr 4:159,927,138...159,946,094
Ensembl chr 4:159,927,139...159,946,029 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19738
    metabolic process 12010
      small molecule metabolic process 1898
        regulation of small molecule metabolic process 389
          regulation of nucleotide metabolic process 55
            regulation of purine nucleotide metabolic process 54
              negative regulation of purine nucleotide metabolic process + 11
              positive regulation of purine nucleotide metabolic process + 26
              regulation of ATP metabolic process + 33
              regulation of NAD metabolic process + 1
              regulation of NADP metabolic process + 7
              regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway + 0
              regulation of purine nucleotide biosynthetic process + 41
              regulation of purine nucleotide catabolic process + 0
              regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA + 0
Path 2
Term Annotations click to browse term
  biological_process 19738
    cellular process 17330
      cellular metabolic process 7444
        heterocycle metabolic process 2950
          nucleobase-containing compound metabolic process 2783
            nucleobase-containing small molecule metabolic process 570
              nucleoside phosphate metabolic process 498
                nucleotide metabolic process 487
                  purine nucleotide metabolic process 431
                    regulation of purine nucleotide metabolic process 54
                      negative regulation of purine nucleotide metabolic process + 11
                      positive regulation of purine nucleotide metabolic process + 26
                      regulation of ATP metabolic process + 33
                      regulation of NAD metabolic process + 1
                      regulation of NADP metabolic process + 7
                      regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway + 0
                      regulation of purine nucleotide biosynthetic process + 41
                      regulation of purine nucleotide catabolic process + 0
                      regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA + 0
paths to the root